Clinical trials: Exercise Tolerance, active
Chronic Pain
Cultivating Activity, Commitment, Tolerance & Uplift Study - for Children With Chronic Pain
The goal of this clinical trial is to learn if the addition of physical exercise and mindfulness training, delivered by a mobile application, to multimodal pain rehabilitation could lead to a mor effective rehabilitation process…
- Trial name
- CACTUS (NCT07485426)
- Testing
- Mobile-based physical exercise and mindfulness training, Pain rehabilitation as usual (PRAU)
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Linkoeping University
Inflammatory Myopathies
Inspiratory Muscle Training in Patients With Inflammatory Myopathy
Inflammatory myopathies are rare autoimmune diseases leading to progressive muscle weakness, often including the respiratory muscles.
- Trial name
- NCT07274267
- Testing
- Inspiratory Muscle Training (IMT)
- Where
- Poland
- Volunteers
- 33 people
- Sponsor
- Józef Piłsudski University of Physical Education
Type 2 Diabetes Mellitus, Obesity
The TRIABETES - ARMMS-T2D Study: A Randomized Trial to Compare Surgical and Medical Treatments for Type 2 Diabetes
This research study is being performed to begin to determine the effectiveness of two dominant bariatric surgery procedures versus an intensive lifestyle intervention to induce weight loss in patients and promote improvements in…
- Trial name
- TRIABETES (NCT01047735)
- Testing
- Roux-en-Y Gastric Bypass Surgery, Laparoscopic Adjustable Gastric Banding, Lifestyle Weight Loss Intervention
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- University of Pittsburgh
Healthy Adults, Mechanical Ventilation Dependence
Effects of Breathing Training and Nitrate on Exercise at Simulated Altitude
This study investigates whether respiratory muscle training (RMT) and dietary nitrate supplementation can improve exercise tolerance under simulated moderate altitude conditions.
- Conditions
- Healthy Adults, Mechanical Ventilation Dependence, Hypoxia, Exercise Training
- Trial name
- NCT07216755
- Testing
- Respiratory Muscle Training (RMT), Dietary Supplement: Beetroot Juice Concentrate
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Embry-Riddle Aeronautical University
Exercise Sensitivity, Introceptive Exposure
Behavioral Exposure for Introceptive Tolerance RCT
Behavioral Exposure for Interoceptive Tolerance (BE-FIT) is a mechanism-informed behavioral intervention to target exercise anxiety.
- Conditions
- Exercise Sensitivity, Introceptive Exposure, Anxiety, Cardiac Rehabilitation
- Trial name
- BE-FIT (NCT05398276)
- Testing
- Behavioral Exposure For Introceptive Tolerance, Health Education Control
- Where
- 3 sites in United States
- Volunteers
- 146 people
- Sponsor
- Rutgers, The State University of New Jersey
Heart Failure With Reduced Ejection Fraction (HFrEF)
Olive Oil Supplementation for Heart Failure With Reduced Ejection Fraction
The OLEA-HF study aims to explore whether daily supplementation of extra-virgin olive oil (EVOO) for 12 weeks during participation in a cardiac rehabilitation program (standard of care) is feasible in patients with heart failure…
- Trial name
- OLEA-HF (NCT07644806)
- Testing
- Extra-virgin olive oil
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Old Dominion University
Heart Failure, Systolic
Paced Heart Rate Acceleration for Cardiac Conditioning
A clinical trial of exercise-similar heart rate acceleration delivered via cardiac pacing vs. sham intervention in subjects at rest will be performed.
- Trial name
- HeartExcel (NCT06332391)
- Testing
- Exercise-similar cardiac pacing
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Denice Hodgson-Zingman, MD
COPD
Physiologic Effects of Nasal High Flow on Exercise Tolerance in COPD
This study aims to assess whether to describe the effects of the administration of nasal high flow (NHF) at 70 liters per minute (L/min) in a 6-Minute Walk Test (6-MWT) among Chronic Obstructive Pulmonary Disease (COPD) patients…
- Trial name
- NCT06578156
- Testing
- Nasal High Flow Cannula, Nasal Low Flow Cannula
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Miami
Intermittent Hypoxia, Exercise Recovery
CPOD Patient's Tolerance of Intermittent Exercise With Inter-exercise Recovery Under Normoxic Hypoxia
Exercise retraining improves the prognosis and quality of life of patients with chronic lung or circulatory diseases. However, exercise intolerance may be caused by excessive ventilatory.
- Conditions
- Intermittent Hypoxia, Exercise Recovery, Intermittent Exercise, Rating Exertion Perception
- Trial name
- HypoChronoPerf (NCT07072975)
- Testing
- Normobaric hypoxia, normoxic condition
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
COPD (Chronic Obstructive Pulmonary Disease)
Inhaled Treprostinil for Dyspnea and Exercise Intolerance in Mild COPD
The goal of this clinical trial is to evaluate the impact of inhaled Treprostinil on breathlessness and low exercise capacity in patients living with mild chronic obstructive pulmonary disease.
- Trial name
- NCT06969573
- Testing
- Treprostinil Inhalation Solution 36 mcg, Treprostinil Inhalation Solution 78 mcg
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Alberta
Heart Failure, Heart Failure, Diastolic
Data-Driven Phenotyping in Heart Failure With Preserved Ejection Fraction
The goal of this observational study is to learn how people with Heart Failure with Preserved Ejection Fraction (HFpEF) can be grouped into different "phenotypes" based on their clinical information.
- Conditions
- Heart Failure, Heart Failure, Diastolic, Heart Failure With Preserved Ejection Fraction (HFPEF)
- Trial name
- NCT07429396
- Where
- 2 sites in Portugal
- Volunteers
- 200 people
- Sponsor
- Instituto Politécnico de Leiria
Multiple Sclerosis, Heat Tolerance
Cooling During Inpatient Rehabilitation in Persons With MS
The goal of this clinical trial is to shed light on the use of cooling during intensive active training sessions during a three-week multidisciplinary inpatient rehabilitation stay in persons with Multiple Sclerosis.
- Conditions
- Multiple Sclerosis, Heat Tolerance, Fatigue Symptom
- Trial name
- CoolEx (NCT07852156)
- Testing
- Wearing a cooling vest during intensive, active training sessions, Control
- Where
- Switzerland
- Volunteers
- 42 people
- Sponsor
- Klinik Valens
Chronic Obstructive Pulmonary Disease (COPD)
Urolithin A Supplementation During Pulmonary Rehabilitation in Patients With COPD
SUPRA-COPD is a multicenter triple-blind, parallel arm, placebo-controlled randomized controlled trial investigating the efficacy and safety of Urolithin A supplementation during pulmonary rehabilitation in patients with COPD.
- Trial name
- SUPRA-COPD (NCT07871357)
- Testing
- Urolithin A
- Volunteers
- 198 people
- Sponsor
- Bryan A. Ross
Chronic Obstructive Pulmonary Disease
Oral Sildenafil for Exercise Capacity, Dyspnea and Cardiopulmonary Function in COPD
Chronic obstructive pulmonary disease (COPD) is a condition characterized by airway obstruction. Patients with COPD experience significant shortness of breath on exertion.
- Trial name
- NCT05061368
- Testing
- Sildenafil Citrate
- Where
- Canada
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Heart Failure, Exercise Tolerance (Measured in Minutes)
High-Flow Nasal Cannula on Exercise Tolerance in Heart Failure Patients Undergoing Cardiac Rehabilitation
The goal of this clinical trial is to learn if a high-flow nasal cannula (HFNC) - a device that delivers warm, humidified air through a small tube placed in the nostrils - can improve exercise tolerance in adults with heart…
- Conditions
- Heart Failure, Exercise Tolerance (Measured in Minutes), Cardiac Rehabilitation
- Trial name
- NCT07613762
- Testing
- High-Flow Nasal Cannula (HFNC)
- Where
- Chile
- Volunteers
- 28 people
- Sponsor
- Universidad de Santiago de Chile
Anaemia, Asthma Exacerbations
Study on Effect of Papworth Technique in Anemic Asthmatic Pediatrics
As asthma is chronic condition which interferes with quality of life and exercise tolerance, so it is important to find out cost-effective alternative for the management of asthma due to increased prevalence and rising health…
- Trial name
- NCT06750354
- Testing
- papworth technique, aerobic training
- Volunteers
- 40 people
- Sponsor
- Cairo University
Parkinson Disease
Effectiveness of Virtual Reality in Parkinson's Disease: Effects on Balance, Fall Risk, and Exercise Capacity.
The goal of this clinical trial is to evaluate whether immersive virtual reality (VR)-based physiotherapy is effective in improving balance, reducing fall risk, and enhancing cardiorespiratory exercise capacity in individuals…
- Trial name
- Parkinson (NCT07251231)
- Testing
- Virtual Reality, Conventional Rehabilitation
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- University of Valencia
Iron Deficiency Anemia, Coronary Artery Disease
Non-Interventional Study of Ferretab® Comp. (Ferrous Fumarate + Folic Acid Prolonged-Release Capsules) Effects in Adult Patients With Iron Deficiency Anemia and Cardiovascular Disease
The goal of this observational study is to learn how well Ferretab® comp. works and how safe it is for adults with iron deficiency anemia and cardiovascular disease who are receiving treatment as part of their usual medical care.
- Conditions
- Iron Deficiency Anemia, Coronary Artery Disease, Heart Failure With Preserved Ejection Fraction (HFPEF)
- Trial name
- PROMETHEUS (NCT07753031)
- Where
- 5 sites in Russia
- Volunteers
- 389 people
- Sponsor
- Alcea
Postural Tachycardia Syndrome
Intravenous (IV) Saline and Exercise in Postural Tachycardia Syndrome (POTS)
The investigators will test whether an intravenous infusion of saline (salt water) will improve the exercise capacity in patients with postural tachycardia syndrome (POTS).
- Trial name
- NCT01000350
- Testing
- Saline
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Vanderbilt University Medical Center
Chronic Lung Diseases
Enhanced External Counterpulsation for Patients With Ventilation Disorders
This study evaluates enhanced external counterpulsation as a non-pharmacological therapy for patients with severe and moderate ventilation disorders due to chronic lung diseases (chronic obstructive pulmonary disease, bronchial…
- Trial name
- NCT07075835
- Testing
- Enhanced external counterpulsation
- Where
- Russia
- Volunteers
- 80 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University