Clinical trials: Exercise Training Adaptation
Healthy Participants
The UBC Long-distance Triathlon Adaptation Study
The purpose of this study is to investigate the effect of 12-months of individualized endurance-training (swimming, cycling and running) on physiological and psychological adaptations in exercise naïve individuals.
- Trial name
- ULTRA (NCT06467656)
- Testing
- Individualized, periodized endurance training for ultra-endurance triathlon., Time-Aligned Control
- Where
- Canada
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Exercise
Protein Supplementation and Endurance Exercise Adaptations
Participants will perform three endurance training sessions weekly for 12 weeks. All participants will be randomly assigned to the protein supplementation group or the placebo (iso-caloric carbohydrate) group.
- Trial name
- NCT03462381
- Testing
- Protein
- Where
- Netherlands
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Exercise Adaptation, Aerobic Capacity
AEROBIC ADAPTATION AND BIOMARKER RESPONSES IN COMBAT ATHLETES
This randomized controlled study investigates the effects of sport-specific training on aerobic adaptation and circulating biomarker responses in trained combat athletes.
- Conditions
- Exercise Adaptation, Aerobic Capacity, Athletic Performance, Combat Sports Training
- Trial name
- AERO-BIO (NCT07473440)
- Testing
- SPORT-SPECIFIC CONDITIONING PROGRAM
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Adiyaman University
Alzheimer's Disease
Alzheimer's Disease and Physiological, Cognitive Function and BDNF Levels of Plasma Adaptation After Exercise Training
Alzheimer's disease (AD) is a neurodegenerative disease leading to one of the most common forms of dementia in humans and memory disorder is one of the first symptoms that lead to diagnosis.
- Trial name
- MARAE (NCT02968875)
- Testing
- Endurance Training, therapeutic education meetings
- Where
- Martinique
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University Hospital Center of Martinique
Exercise Training, Skeletal Muscle
Resistance Training, Detraining, and Retraining Study 2022
The research project is aiming to examine the muscular adaptations to resistance training (RT), detraining (DT) and repeated RT (i.e. retraining).
- Conditions
- Exercise Training, Skeletal Muscle, Skeletal Muscle Atrophy
- Trial name
- TraDeRe2022 (NCT05553769)
- Testing
- Resistance training, detraining, retraining
- Where
- Finland
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Jyvaskyla
Athletic Performance, Physical Fitness
Effects of 8-Week Plyometric Training on Basketball Performance and Isokinetic Strength
This study aims to evaluate the effects of an 8-week plyometric training program on the physical performance of male basketball players.
- Conditions
- Athletic Performance, Physical Fitness, Muscle Strength, Plyometric Exercise Adaptations
- Trial name
- PT-BASKET (NCT07399548)
- Testing
- 8-Week Progressive Plyometric Training Program
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Kastamonu University
Heat Exposure, Exercise Training
Mechanisms Underlying Hypoxic, Heat and Cross-tolerance Adaptation in Women
This study will consist of a parallel-groups design, with 30 healthy active female participants randomly assigned to either an experimental heat acclimation and exercise intervention, or a thermo-neutral exercise intervention…
- Trial name
- FemAdapt_HOT (NCT06575985)
- Testing
- Heat acclimation and exercise training, Thermo-neutral exercise training group
- Where
- 2 sites in Slovenia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Jozef Stefan Institute
Frail Elderly Syndrome, Frailty
Keeping Active in Residential Elderly
This trial will take the form of a feasibility study; designed to assess the feasibility of a proposed future clinical trial in this setting.
- Conditions
- Frail Elderly Syndrome, Frailty, Physical Activity
- Trial name
- KARE (NCT03141879)
- Testing
- HUR equipment resistance training intervention
- Where
- United Kingdom
- Volunteers
- 48 people
- Sponsor
- University of Birmingham
Biological Aging
Sex-specific Adaptation to Resistance Training in Older Adults
In general, men and women experience differing degrees of age-related decreases in physical function, with women having a greater prevalence of functional limitations and disability.
- Trial name
- NCT03440099
- Testing
- Resistance exercise training
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Amherst
Athletic Performance, Soccer
The Effect of a Training Programme in the Variation of Fitness Parameters, Physiological, Hematological and Biochemical Indicators of Soccer Players During the Preseason Period
The goal of this study is to investigate the effects of varying friendly match-play exposure during the late pre-season on physiological, biochemical, and performance adaptations in soccer players.
- Conditions
- Athletic Performance, Soccer, Muscle Damage, Inflammation
- Trial name
- NCT07170930
- Testing
- Friendly Match-Play Exposure: extended vs. limited
- Where
- Greece
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Emmanouil D. Zacharakis
Overweight (BMI > 25), Males and Females
IMPACT: Immune and Musculoskeletal Physiological Adaptations to Combined Exercise Training & Nutrition
The purpose of this study is to determine whether 12 weeks of exercise training combined with dairy consumption influences inflammation and immune responses in adults with overweight, compared to exercise training alone.
- Trial name
- NCT07513987
- Testing
- Milk, Greek Yogurt, Exercise training
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- York University
Exercise
Interference of Endurance Training on Strength Development and Neuromuscular Adaptations
This study aims to find out if performing combined strength and endurance exercise in the same program (called concurrent training-CT) leads to similar long-term improvements in neuromuscular function as doing each type of…
- Trial name
- NCT06378762
- Testing
- Endurance Exercise, Strength Exercise, Concurrent Exercise
- Where
- Portugal
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Lisbon
Type2diabetes
Exercise Training and Type 2 Diabetes
Objective: This study investigates the effects of hybrid training in the form of small-sided football games on health status, blood glucose regulation, muscle metabolism, and well-being in patients with type 2 diabetes mellitus…
- Trial name
- NCT06478173
- Testing
- Exercise training
- Where
- Faroe Islands
- Volunteers
- 126 people
- Sponsor
- University of the Faroe Islands
Altitude Training, Race Walking
Effects of Alternating Altitude Training Versus Fixed-Altitude Training on Exercise Capacity and Physiological Adaptations in Elite Race Walkers: A Randomized Controlled Trial
This randomized controlled trial aims to compare the effects of alternating altitude training and fixed-altitude training on physical performance and physiological adaptations in elite race walkers living at altitude.
- Trial name
- NCT07718009
- Testing
- Alternating Altitude Training, Fixed-Altitude Training
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Macao Polytechnic University
Cardiovascular Fitness
Adaptations to 4-s Sprint Interval Training at Different Intensities
The purpose of this study is to investigate the chronic effects (i.e., 8 weeks, 3 times per week) of training at 50% and 75% of maximal power with 4-s sprint interval training on physiological adaptations.
- Trial name
- NCT06906393
- Testing
- Preventive treatment
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Healthy, Healthy Participants
Acute Effects of Structured Exercise and Static Stretching on Vascular Function, Neuromuscular Performance, and Metabolic Regulation in Adults
This experimental study investigates the acute cardiovascular and vascular responses to a single session of resistance training, with and without additional static stretching, compared with a resting control condition.
- Conditions
- Healthy, Healthy Participants, Healthy Subjects (HS), Resistance Training Adaptation
- Trial name
- NCT07364149
- Testing
- Resistance Training, Resistance training + Static Stretching
- Where
- Italy
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Palermo
Supportive Care, Exercise Adaptations
Intradialytic Exercise and Cognitive Function
Exercise training may improve global and domain-specific cognitive function, mental health, psychological well-being, dialysis efficacy, and health-related quality of life in people with end-stage kidney disease receiving…
- Conditions
- Supportive Care, Exercise Adaptations, Exercise Training Therapy, Clinical Exercise
- Trial name
- EXCOG-HD (NCT07780175)
- Testing
- Resistance Training, Aerobic training, Combination Training
- Where
- Cyprus
- Volunteers
- 60 people
- Sponsor
- University of Thessaly
Hypertrophy, Strength Training Adaptations
Dileucine and Resistance Training Adaptations
This study seeks to compare the observed changes in resistance training adaptations after supplementation of isomolar amounts of leucine or dileucine in healthy resistance-trained men.
- Conditions
- Hypertrophy, Strength Training Adaptations, Weight-Bearing Strengthening Program
- Trial name
- DTS (NCT06121869)
- Testing
- Leucine, Dileucine
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Lindenwood University
Obesity
Progressive Metabolic Adaptations to Low Intensity Exercise Training and Weight Loss
the investigators first aim is to determine the effect of low intensity exercise (without weight loss) on insulin sensitivity, muscle lipid metabolism, and factors regulating these processes in skeletal muscle after 1 day, 2 wks…
- Trial name
- NCT01452074
- Testing
- Exercise Training, Weight Loss with continued Exercise Training
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Cardiovascular Diseases, Coronary Artery Disease
The Effect Of An Expanded Long Term Periodization Exercise Training In Patients With Cardiovascular Disease
Benefits from cardiac rehabilitation (CR) programs are evidence based and widely recognized. Less than 50% of people who participate in hospital-based CR programs maintain an exercise regimen for as long as six months after…
- Trial name
- NCT03335319
- Testing
- Periodized Exercise Training Regime, Non Periodized Exercise Training Regime
- Where
- Portugal
- Volunteers
- 50 people
- Sponsor
- University of Lisbon