Clinical trials: Exercise-Induced Inflammation
Exercised Induced Asthma, Asthma
The Effects of Prebiotics on Gut Bacterial Parameters, Immune Function & Exercise-Induced Airway Inflammation.
The current study aims to explore the role of prebiotic supplementation in adults with and without Asthma/Exercise-Induced Bronchoconstriction (A/EIB).
- Trial name
- NCT02872675
- Testing
- HOST-DM059, Maltodextrin
- Where
- United Kingdom
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Nottingham Trent University
Athletic Performance, Physical Endurance
Event-Specific Adaptations to CrossFit and Running-Based HIIT in Elite Distance Runners at Moderate Altitude
The goal of this clinical trial is to compare the effects of two high-intensity training programs on physical performance and physiological adaptations in elite male middle- and long-distance runners aged 25 to 35 years who live…
- Conditions
- Athletic Performance, Physical Endurance, Altitude Training Adaptation, Aerobic Capacity
- Trial name
- NCT07675577
- Testing
- Running-Based High-Intensity Interval Training (HIIT), CrossFit-Based High-Intensity Training (CF)
- Where
- Iran
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Sistan and Baluchestan
Muscular Injury
Turmeric and Exercise-Induced Muscle Damage and Oxinflammation
The purpose of this study is to measure the effect of using a turmeric-based supplement for 2-weeks on muscle damage and soreness that occur in the body after 90-minutes of exercise.
- Trial name
- NCT04765527
- Testing
- Turmeric Strength for Joint
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
Performance Recovery, Exercise-induced Inflammation
S-Acetyl Glutathione and Performance Recovery in Soccer
Soccer players display elevated inflammatory and oxidative stress markers combined with reduced soccer specific performance over a 72-hour period.
- Conditions
- Performance Recovery, Exercise-induced Inflammation, Exercise-induced Oxidative Stress
- Trial name
- NCT07690124
- Testing
- 200 mg S-Acetyl Glutathione, 500 mg S-Acetyl Glutathione
- Where
- Greece
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Skeletal Muscle Damage, Skeletal Muscle Performance
NAC Supplementation and Skeletal Muscle Performance
In this investigation the investigators utilized NAC administration to foster GSH availability during an 8-day period following eccentric exercise-induced muscle damage in order to test our hypotheses: i) antioxidant…
- Conditions
- Skeletal Muscle Damage, Skeletal Muscle Performance, Intgracellular Signaling in Skeletal Muscle, Inflammatory Status
- Trial name
- NCT01778309
- Testing
- n-acetylcysteine supplementation
- Where
- Greece
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Democritus University of Thrace
Muscle Damage, Muscle Soreness
The Effects of Whey Protein Supplements on Markers of Exercise-induced Muscle Damage in Resistance-trained Individuals
Intense exercise can bring about various side effects to one's body. Less range of motion, increased pain sensitivity, increased muscle swelling, and decreased muscle strength can occur immediately after exercise.
- Trial name
- WheyProtein (NCT05100459)
- Testing
- Pasture-raised whey protein, Conventional whey protein
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Indiana University
Exercise-induced Inflammation
Effect of Combined Fatty Acid Supplementation and Eccentric Exercise Training on Exercise Performance
The aim of the study is to determine whether fish oil (specifically omega-3 long chain polyunsaturated fatty acids [EPA-DHA]) supplementation can enhance eccentric resistance exercise performance when combined with a resistance…
- Trial name
- FAT (NCT03259412)
- Testing
- Fish Oil
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Oxidative Stress, Healthy
A Randomized, Double-Blind Study to Assess the Effect of a Postbiotic on Oxidative Stress and Exercise Performance
This is a prospective, randomized, placebo controlled, double-blind study to assess the effects of a postbiotic blend on exercise induced oxidative stress markers and exercise performance in healthy adult.
- Conditions
- Oxidative Stress, Healthy, Exercise-induced Muscle Damage, Exercise-induced Muscle Soreness
- Trial name
- PBE (NCT06795425)
- Testing
- Postbiotic Active Lifestyle Blend
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Lindenwood University
Oxidative Stress, Inflammation
Probiotic Sport Study
We investigate the impact of a probiotic-based dietary supplement on oxidative stress and endotoxemia before and after strenuous exercise.
- Conditions
- Oxidative Stress, Inflammation, Endotoxemia
- Trial name
- NCT01474629
- Testing
- probiotic-based dietary supplement
- Where
- Austria
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Green Beat
Exercise-induced Bronchospasm
Mechanisms of Exercise-induced Bronchospasm
The term exercise-induced bronchospasm (EIB) describes acute, transient airway narrowing that occurs during, and most often after, exercise.
- Trial name
- NCT00701025
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Skeletal Muscle Damage, Exercise-induced Aseptic Inflammation
Aloe Vera Ointment Application and Skeletal Muscle Recovery
Aloe vera, sometimes described as pharmaceutical aloe, is a flowering succulent plant with many therapeutic properties such as wound and burn wound healing, treatment of diabetes and reduction of blood lipid profile.
- Conditions
- Skeletal Muscle Damage, Exercise-induced Aseptic Inflammation, Performance
- Trial name
- NCT03934762
- Testing
- Natural Aloe Vera, Aloe vera soup
- Where
- Greece
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Exercise-induced Muscle Damage, Oxidative Stress
New Zealand Blackcurrant and Recovery in Elite Taekwondo
This randomized, double-blind, placebo-controlled trial evaluated the effects of short-term supplementation with anthocyanin-rich New Zealand blackcurrant (NZBC) extract on exercise-induced muscle damage, oxidative stress…
- Conditions
- Exercise-induced Muscle Damage, Oxidative Stress, Inflammation, Recovery After Exercise
- Trial name
- NZBC-TAE (NCT07828444)
- Testing
- New Zealand Blackcurrant Extract (CurraNZ®)
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Skeletal Muscle Damage, Exercise-induced Aseptic Inflammation
Protein Supplementation and Skeletal Muscle Healing Process
In this study the investigators utilized protein supplementation over an 8-day period following eccentric exercise-induced muscle damage in order to test the initial hypotheses : i) protein supplementation after exercise-induced…
- Conditions
- Skeletal Muscle Damage, Exercise-induced Aseptic Inflammation, Skeletal Muscle Performance, Intracellular Signaling in Skeletal Muscle
- Trial name
- NCT02816411
- Testing
- Milk protein isolate
- Where
- Greece
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Inflammation; Muscle
Effectiveness of Two Different Forms of Marine Oil on Indirect Markers of Muscle Damage and Soreness in Untrained Men
To evaluate the effects of PCSO-524®, and a blend of PCSO-24® (75%) and krill oil (25%) (ESPO-572®), on indirect markers of muscle damage, inflammation and soreness during recovery from muscle damaging exercise in untrained men.
- Trial name
- NCT03760757
- Testing
- ESPO-572®, PCSO-524®
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Indiana University
Exercise Induced Muscle Damage, Physical Activity
Walk It Off! the Influence of Physical Activity Level on the Recovery from Damaging Resistance Exercise
After completing novel activity or exercise we may experience exercise-induced muscle damage (EIMD), resulting in a period of reduced muscle function and delayed onset muscle soreness (DOMS).
- Conditions
- Exercise Induced Muscle Damage, Physical Activity, Inflammation, Exercise Recovery
- Trial name
- WIO (NCT06810271)
- Testing
- Eccentric resistance exercise
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Exercise Induced Muscle Damage, Cryotherapy
Acute Cryotherapy on Musculoskeletal Function and Biomarkers
In 2020, Dubois and Esculier proposed a paradigm shift in the acute management of musculoskeletal injuries, advocating for the transition from the traditional PRICE protocol- Protect, Rest, Ice, Compression, Elevation-to the more…
- Trial name
- NCT07211412
- Testing
- Cryotherapy, Eccentric exercise-induced muscle damage
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Texas, El Paso
Athletic Performance, Soccer
The Effect of a Training Programme in the Variation of Fitness Parameters, Physiological, Hematological and Biochemical Indicators of Soccer Players During the Preseason Period
The goal of this study is to investigate the effects of varying friendly match-play exposure during the late pre-season on physiological, biochemical, and performance adaptations in soccer players.
- Conditions
- Athletic Performance, Soccer, Muscle Damage, Inflammation
- Trial name
- NCT07170930
- Testing
- Friendly Match-Play Exposure: extended vs. limited
- Where
- Greece
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Emmanouil D. Zacharakis
Muscle Injury, Muscle Soreness
Effects of Wobenzym® Plus in Healthy, Sportive People After Eccentric Exercise
The aim of the current study is to investigate the therapeutic effect and especially the mode of action of Wobenzym® plus, an anti-inflammatory drug containing proteolytic enzymes, on exercise induced muscle damage (eiMD) and…
- Conditions
- Muscle Injury, Muscle Soreness, Exercise Induced Muscle Damage
- Trial name
- 2012-005003-40 (NCT01845558)
- Testing
- Wobenzym® plus
- Where
- Germany
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Mucos Pharma GmbH & Co. KG
Inflammatory Response
Blueberry-protein Supplementation and Exercise
This study is the human clinical trial component of an SBIR grant with Sinnovatek (funded). Cyclists (n=20) will consume a blueberry-protein, blueberry, or placebo supplement for 2 weeks prior to cycling for 2.5 h at high…
- Trial name
- NCT05596500
- Testing
- Blueberry-protein gel, Blueberry gel
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
Myalgic Encephalomyelitis, Chronic Fatigue Syndrome
Cardiopulmonary Testing in ME/CFS to Improve Diagnostic Accuracy
Circumstantial evidence suggests that patients diagnosed with myalgic encephalopathy/chronic fatigue syndrome (ME/CFS) perform worse on day 2 in a 2-day consecutive cardiopulmonary exercise test (CPET).
- Trial name
- NCT02970240
- Testing
- Cardiopulmonary testing
- Where
- Norway
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Oslo