Clinical trials: Exercise-Induced Muscle Damage
Muscle Damage, Muscle Soreness
The Effects of Restriction Pressure on Muscle Damage Responses to Blood Flow Restriction Exercise
Blood flow restriction (BFR) exercise involves the application of a constriction device to the limbs to restrict muscle blood flow during exercise.
- Conditions
- Muscle Damage, Muscle Soreness, Muscle Strength
- Trial name
- NCT05037942
- Testing
- Blood flow restriction at 40% limb occlusion pressure, Blood flow restriction at 80% limb occlusion pressure
- Where
- United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Exercise Induced Muscle Damage
Exercise Induced Muscle Damage Post Dance and Sprint Specific Exercise in Females
There is a paucity of studies investigating exercise-induced muscle damage (EIMD) in females and only one in response to dance-type exercise.
- Trial name
- NCT03284450
- Testing
- DPFT, SSRS
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Iron-deficiency, Inflammation
Iron and Muscular Damage: FEmale Metabolism and Menstrual Cycle During Exercise
This project is an observational controlled randomized counterbalance study. One hundred and three physically active and healthy women were selected to participate in the IronFEMME Study, of which 57 were eumenorrheic, 30 were…
- Conditions
- Iron-deficiency, Inflammation, Exercise Induced Iron-deficiency, Exercise Induced Muscle Damage
- Trial name
- IronFEMME (NCT04458662)
- Testing
- Interval running protocol / eccentric-based resistance exercise protocol
- Where
- Spain
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Universidad Politecnica de Madrid
Exercise Induced Muscle Damage
Muscle Health and Recovery in Older Adults
This is a prospective, randomized, placebo controlled, double-blinded study to evaluate the efficacy of a combination of nutritional ingredients on muscle health and recovery from a short bout of exhaustive exercise in healthy…
- Trial name
- NCT06205537
- Testing
- Control Liquid Supplement, Experimental Liquid Supplement
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Abbott Nutrition
Exercise-induced Muscle Damage
Effect of Total Cold Water Immersion Vs Ice Massage Modalities
Evidence regarding the effect of the therapeutic modalities on muscle recovery after exercise-induced muscle damage (EIMD) was lacking.
- Trial name
- NCT04183816
- Testing
- Total cold-water immersion, Ice massage
- Where
- Lebanon
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Lebanese German University
Skeletal Muscle Damage, Exercise-induced Aseptic Inflammation
Protein Supplementation and Skeletal Muscle Healing Process
In this study the investigators utilized protein supplementation over an 8-day period following eccentric exercise-induced muscle damage in order to test the initial hypotheses : i) protein supplementation after exercise-induced…
- Conditions
- Skeletal Muscle Damage, Exercise-induced Aseptic Inflammation, Skeletal Muscle Performance, Intracellular Signaling in Skeletal Muscle
- Trial name
- NCT02816411
- Testing
- Milk protein isolate
- Where
- Greece
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Cold-water Immersion, Protein-carbohydrates Supplementation
Effects on CK, RPE, VAS Scale and Physical Performance of Three Recovery Methods in Elite Basketball Players
The aim of this study was to compare the effects of cold water intermittent ion (CWI), carbohydrate and protein supplementation (SUPPL), and active recovery (ACT) on creatine kinase (CK), perceptual and performance markers of…
- Conditions
- Cold-water Immersion, Protein-carbohydrates Supplementation, Active Recovery, Placebo
- Trial name
- NCT05805540
- Testing
- Cold-water immersion, Protein-carbohydrates supplementation, Active recovery
- Where
- Spain
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Cadiz
Oxidative Stress, Healthy
A Randomized, Double-Blind Study to Assess the Effect of a Postbiotic on Oxidative Stress and Exercise Performance
This is a prospective, randomized, placebo controlled, double-blind study to assess the effects of a postbiotic blend on exercise induced oxidative stress markers and exercise performance in healthy adult.
- Conditions
- Oxidative Stress, Healthy, Exercise-induced Muscle Damage, Exercise-induced Muscle Soreness
- Trial name
- PBE (NCT06795425)
- Testing
- Postbiotic Active Lifestyle Blend
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Lindenwood University
Healthy
Genetic Determinants of Exercise-Induced Muscle Damage (POLYGENDOMUS)
The objective of this study is to evaluate the association between the evolution of plasma CPK levels and genetic polymorphisms, both before the muscle-damaging exercise and at three post-exercise time points.
- Trial name
- POLYGENDOMUS (NCT06740136)
- Testing
- Exercise
- Where
- France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Lille University
Post-Exercise Recovery
Effect of Chickpea Protein Hydrolysate Supplementation on Muscle Damage and Inflammatory Plasma Markers During a Football Tournament: A Randomized, Placebo-Controlled Crossover Trial
This randomized, placebo-controlled crossover study evaluated the safety and potential beneficial effects of a beverage containing chickpea protein hydrolysate in football players.
- Trial name
- PROVERDE (NCT07765719)
- Testing
- Chickpea Protein Hydrolysate Beverage
- Where
- Spain
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Instituto de la Grasa
Eccentric Hypertrophy, Muscle Damage
Comparing Two Eccentric Protocols on Muscle Damage
The purpose of this study will be to test whether a new way of weight training is more effective than typical weight training. The investigators expect that this new way will cause more exercise-induced muscle damage, which helps…
- Trial name
- NCT06992271
- Testing
- Fast Eccentric, Slow Eccentric
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- New York Institute of Technology
Exercise-induced Muscle Damage, Oxidative Stress
New Zealand Blackcurrant and Recovery in Elite Taekwondo
This randomized, double-blind, placebo-controlled trial evaluated the effects of short-term supplementation with anthocyanin-rich New Zealand blackcurrant (NZBC) extract on exercise-induced muscle damage, oxidative stress…
- Conditions
- Exercise-induced Muscle Damage, Oxidative Stress, Inflammation, Recovery After Exercise
- Trial name
- NZBC-TAE (NCT07828444)
- Testing
- New Zealand Blackcurrant Extract (CurraNZ®)
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Exercise Induced Muscle Damage
The Effect of Curcumin Supplementation on Recovery From Exercise-induced Muscle Damage
Recent evidence suggests that curcumin supplementation may reduce muscle inflammation, oxidative markers, and muscle damage. The most favourable dosage to elicit these ergogenic effects are yet to be established; both 750mg \&…
- Trial name
- NCT05346211
- Testing
- Curcumin
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- St Mary's University College
Exercise-Induced Muscle Damage, Rhabdomyolysis
DOES LOWER BODY PLYOMETRICS CAUSE RHABDOMYOLYSIS IN FEMALE VOLLEYBALL PLAYERS-AN EXPERIMENTAL STUDY
Eight-week interventional study to evaluate whether lower-body plyometric training alters serum creatine phosphokinase (CPK) and creatinine levels in female collegiate volleyball players.
- Conditions
- Exercise-Induced Muscle Damage, Rhabdomyolysis, Athletes
- Trial name
- NCT07352319
- Testing
- plyometric program
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Recovery, Muscle Damage
Recovery From 50 Eccentric Biceps Curls in Young, Untrained Men and Women
The purpose of the study is to investigate muscle stiffness in relation to muscle damaging work and to investigate how well the change in muscle stiffness correlates with the degree of muscle damage (myofibrillar disruption and…
- Conditions
- Recovery, Muscle Damage, Muscle Stiffness, Cell Structure Alteration
- Trial name
- NCT05036239
- Testing
- Eccentric biceps curls
- Where
- Norway
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Norwegian School of Sport Sciences
Muscle Weakness, Muscle Damage
Acute Physiological Responses to Twice Daily Blood Flow Restriction Training
The Academic Department of Military Rehabilitation (ADMR) is currently conducting a pan-defence, randomised control trial (RCT) investigating the utility of twice daily blood flow restriction training in UK military personnel…
- Trial name
- NCT06334224
- Testing
- Low load resistance training with blood flow restriction, Low load resistance training
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Defence Medical Rehabilitation Centre, UK
Muscle Damage, Inflammation
Branched-chain Amino Acids Supplementation and Resistance Exercise-induced Muscle Damage and Inflammation
This study aims to evaluate the effects of branched-chain amino acids (BCAA) supplementation on resistance exercise-induced muscle damage and inflammation.
- Trial name
- NCT01305018
- Testing
- BCAA, Leucine
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Muscle Damage
The Effect of New Zealand Blackcurrant (NZBC) Supplementation on Recovery Following Strenuous Exercise
The study aims to examine the effect of a New Zealand blackcurrant (NZBC) supplement on markers of muscle damage and recovery following strenuous resistance exercise.
- Trial name
- CurraNZ_MD (NCT05010057)
- Testing
- New Zealand blackcurrants (NZBC)
- Where
- United Kingdom
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Exercise-Induced Muscle Damage, Delayed Onset Muscle Soreness (DOMS)
Curcumin Versus Ibuprofen for Exercise-Induced Muscle Damage in Physically Active Women
xercise-induced muscle damage (EIMD) is a common consequence of unaccustomed or high-intensity exercise and is characterized by muscle soreness, impaired physical performance, inflammation, oxidative stress, and increased…
- Conditions
- Exercise-Induced Muscle Damage, Delayed Onset Muscle Soreness (DOMS), Sports Recovery, Exercise-Induced Oxidative Stress
- Trial name
- CURACTIVE (NCT07785986)
- Testing
- Curcumin, Ibuprofen
- Where
- Spain
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Valladolid
Young Athletes
Effects of Manual Lymphatic Drainage and Pressotherapy on Muscle Recovery After Eccentric Exercise in Physically Active Young Adults
This randomized controlled trial aims to compare the effects of manual lymphatic drainage (MLD), intermittent pneumatic compression (IPC), and passive rest on recovery following exercise-induced muscle damage (EIMD) induced by a…
- Trial name
- LYMPH-REC (NCT07892105)
- Testing
- Manual Lymphatic Drainage, Intermittent Pheumatic Compression
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Camilo Jose Cela University