Clinical trials: Exercise-induced Muscle Soreness
Delayed Onset Muscle Soreness (DOMS), Exercise-Induced Muscle Soreness
A Study of Mitragynine Formulations for Exercise-Induced Muscle Soreness in Healthy Adults
This Phase II randomized, double-blind, placebo-controlled study will evaluate the safety, tolerability, and physical dependence potential of mitragynine-containing formulations after 28 days of use and assess their effects on…
- Trial name
- NCT07809282
- Testing
- SpecioTea, MitraPlex
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Traditional Naturals Research Inc.
Myalgic Encephalomyelitis, Chronic Fatigue Syndrome
Cardiopulmonary Testing in ME/CFS to Improve Diagnostic Accuracy
Circumstantial evidence suggests that patients diagnosed with myalgic encephalopathy/chronic fatigue syndrome (ME/CFS) perform worse on day 2 in a 2-day consecutive cardiopulmonary exercise test (CPET).
- Trial name
- NCT02970240
- Testing
- Cardiopulmonary testing
- Where
- Norway
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Insomnia, Healthy Adult
The Impact of Insomnia on Pain Sensitivity and the Trajectory of Exercise-induced Muscular Pain
Sleep is a critical determinant of physiological recovery and pain regulation. Growing evidence suggests that sleep disruption directly heightens central and peripheral pain sensitivity to sensory stimuli (e.g., mechanical…
- Conditions
- Insomnia, Healthy Adult, Musculoskeletal Pain, Pain Sensitivity
- Trial name
- NCT07827664
- Testing
- Eccentric exercise
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Muscle Pain
Study of Etoricoxib for the Treatment of Muscle Pain and Inflammation Induced by Eccentric Exercise
Comparison of the effect of etoricoxib to placebo on muscle pain caused by eccentric contractions
- Trial name
- NCT01271348
- Testing
- Etoricoxib
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- X-pert Med GmbH
Muscular Regeneration, Repeated Bout Effect of WB-EMS
Effects of Compression Wear on Muscle Soreness
The study address two main topics: 1. The effect of compression garment on whole-body electromyostimulation (WB-EMS) induced muscle soreness in young adults 2.
- Trial name
- COMDOME (NCT03417323)
- Testing
- Compression
- Where
- 2 sites in Germany
- Volunteers
- 23 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Exercise-Induced Fatigue, Football Performance
Effects of Hydrogen-rich Water Consumption on Transient Fatigue During an Official Football Match.
The purpose of this study is to determine whether drinking hydrogen-rich water can reduce fatigue and help football players maintain high-intensity physical activity during an official football match.
- Trial name
- HRW-FOOTBALL (NCT07855120)
- Testing
- Hydrogen-Rich Water (HRW)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Palacky University
Insomnia, Healthy Adult
The Effect of Different rTMS Interventions on Acute Experimental Muscular Pain in Individuals Comorbid With Insomnia
Insomnia exacerbates pain sensitivity and impairs physiological recovery from acute musculoskeletal pain. Repetitive transcranial magnetic stimulation (rTMS) has emerged as a promising non-invasive neuromodulation intervention to…
- Conditions
- Insomnia, Healthy Adult, Exercise Induced Muscle Damage, Pain Sensitivity
- Trial name
- NCT07827677
- Testing
- Repetitive transcranial magnetic stimulation (rTMS) on L M1, Repetitive transcranial magnetic stimulation (rTMS) on R DLPFC
- Where
- Hong Kong
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Delayed Onset Muscle Soreness
Comparison of Dry Needle and Massotherapy on Tolerance Effort and Soreness
Introduction: Delayed onset muscle soreness (DOMS) is a common myogenic condition considered to be a muscle tension injury frequently observed in recreational or experienced athletes, induced in the majority of cases by eccentric…
- Trial name
- NCT03619928
- Testing
- Dry needling, Massotherapy
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Musculoskeletal Pain, Healthy
Multivariable Recovery After Exercise-induced Muscle Pain in the Forearm Muscles
This study investigates the evolution of sensory, motor and tissue variables following exercise-induced pain in wrist extensor muscles in healthy subjects.
- Conditions
- Musculoskeletal Pain, Healthy, Delayed Onset Muscle Soreness
- Trial name
- NCT04012203
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad San Jorge
Encephalomyelitis, Myalgic, Chronic Fatigue Syndrome
Effect of Stellate Ganglion Block on ME/CFS
The goal of this clinical trial is to study the effects of stellate ganglion block (SGB) in participants with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).
- Conditions
- Encephalomyelitis, Myalgic, Chronic Fatigue Syndrome, Chronic Fatigue Disorder, Chronic Fatigue and Immune Dysfunction Syndrome
- Trial name
- SGB_ME (NCT05664711)
- Testing
- Bupivacaine Injection
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Neuroversion, Inc.
Exercise-induced Muscle Soreness
Effects of Traumeel®S Tablets on Exercise Induced Muscle Damage and Muscle Soreness
To investigate and compare the effects of Traumeel®S tablets versus placebo on exercise induced muscle damage and muscle soreness for 72 hours after strenuous eccentric exercise test on downhill treadmill.
- Trial name
- NCT01912469
- Testing
- Traumeel
- Where
- Germany
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. med. Frank Christoph Mooren
Muscle Recovery
Investigating the Efficacy of Low or High Dose Tart Cherry on Recovery From Exercise Induced Muscle Damage and Establishing Its Molecular Mechanisms of Action
To determine the dose-response effects of 10-day tart cherry product consumption (0, 30 ml, and 60 ml) on knee extensor isometric strength 24-h and 48-h after muscle damaging exercise and to elucidate the mechanisms of action for…
- Trial name
- NCT04725149
- Testing
- 500 ml base solution, 500 ml containing 30 ml tart cherry concentrate diluted with water and base solution, 500 ml containing 60 ml tart cherry concentrate diluted with water only
- Where
- United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Fatigue Syndrome, Chronic, Cardiovascular Diseases
Is Post-exertional Symptom Exacerbation Specific to Patients With Myalgic Encephalomyelitis / Chronic Fatigue Syndrome? A Study Comparing Patients With Myalgic Encephalomyelitis / Chronic Fatigue Syndrome and Patients With Cardiac Diseases Who Underwent an Exercise Test.
Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME/CFS) is a disease characterized by persistent and unexplained fatigue associated with diffuse pain, sleep disorders, neurocognitive and autonomic symptoms, musculoskeletal…
- Trial name
- MAPEMCAR (NCT07491315)
- Testing
- Exercise test on ergocycle, Near Infrared Spectroscopy (NIRS)
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Hôpital Européen Marseille
Delayed Onset Muscle Soreness
The Preventive Effects of Neurodynamic Mobilisation
In the study, 34 healthy sedentary male volunteers were randomly divided into two groups as NM (n = 17) and SHAM-NM (n = 17). After the initial evaluation of the individuals, femoral nerve NM and placebo NM techniques were…
- Trial name
- NCT05326893
- Testing
- Femoral nerve neurodynamic mobilization
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Uğur Sözlü
Myalgia [C05.651.542]
Cryotherapy and Laser Therapy on Muscle Damage
This study propose investigate the effect of cryotherapy and laser therapy in response to strenuous exercise-induced muscle damage on the biceps brachii muscle (muscle of the arms).
- Trial name
- CLMD (NCT02327988)
- Testing
- Cryotherapy, Laser therapy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio Grande do Norte
Exercise Induced Muscle Damage
Indirect Biomarkers and Exercise Induced Muscle Damage
The purpose of this study is to investigate the magnitude of changes in biomarkers of exercise-induced muscle damage following an acute bout of eccentric exercise of the knee extensors performed on an isokinetic dynamometer.
- Trial name
- NCT07503860
- Testing
- Eccentric Exercise
- Where
- Greece
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Vassilis Paschalis
Muscle Damage, Inflammation
Protein and Recovery From Exercise-induced Muscle Damage
Intense, eccentric resistance exercise causes muscle damage, soreness, inflammation, and a loss of muscle function. Protein-amino acid supplementation before, during, and following damaging resistance exercise may reduce muscle…
- Trial name
- NCT02034721
- Testing
- Protein supplement
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
Old Age; Atrophy, Inflammatory Response
Effects of Parmigiano Reggiano on Skeletal Muscle Damage in Older Adults
Aging is associated with the loss of muscle mass and function (sarcopenia) and reduced tissue regenerative capacity. Eccentric exercise (ECC) is a model of RET that can be used with the elderly, due to the ability of the muscle…
- Conditions
- Old Age; Atrophy, Inflammatory Response, Muscle Soreness
- Trial name
- NCT04872374
- Testing
- Parmigiano Reggiano, Whey Protein
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Padova
Post-Acute COVID-19 Syndrome, ME/CFS
Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research
The unhide® Project is a non-interventional, longitudinal research study designed to establish a secure data repository of demographic, health, and lifestyle information from individuals with brain inflammation and related…
- Conditions
- Post-Acute COVID-19 Syndrome, ME/CFS, Rheumatic Arthritis, Juvenile Rheumatoid Arthritis (JRA)
- Trial name
- NCT04806620
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Brain Inflammation Collaborative
Exercise-Induced Muscle Damage, Delayed Onset Muscle Soreness (DOMS)
Curcumin Versus Ibuprofen for Exercise-Induced Muscle Damage in Physically Active Women
xercise-induced muscle damage (EIMD) is a common consequence of unaccustomed or high-intensity exercise and is characterized by muscle soreness, impaired physical performance, inflammation, oxidative stress, and increased…
- Conditions
- Exercise-Induced Muscle Damage, Delayed Onset Muscle Soreness (DOMS), Sports Recovery, Exercise-Induced Oxidative Stress
- Trial name
- CURACTIVE (NCT07785986)
- Testing
- Curcumin, Ibuprofen
- Where
- Spain
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Valladolid