Clinical trials: Exposure
Glucose Metabolism, Glucagon
Investigating the Acute Effects of Increasing Alanine Exposure in Healthy Participants
In this study the investigators will investigate the acute effects of increasing alanine exposure on metabolic parameters in healthy participants. Participants will participate in one study day.
- Trial name
- NCT07350512
- Testing
- alanine
- Where
- Denmark
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Nicolai Jacob Wewer Albrechtsen
Non Communicable Diseases, Microbiome
Mapping the Health Status of the Population of French Polynesia: the MATAEA Project
This is a cross-sectional study carried out on a sample of the adult population aged 18 to 69, distributed over the five archipelagos of French Polynesia.
- Conditions
- Non Communicable Diseases, Microbiome, Communicable Diseases, Pesticide Exposure
- Trial name
- MATAEA (NCT06133400)
- Testing
- Questionnaire, Physical measurements, Biological samples
- Where
- French Polynesia
- Volunteers
- 1,942 people, healthy volunteers welcome
- Sponsor
- Institut Louis Malardé
Asthma, Incentives
Financial Incentives to Reduce Pediatric Tobacco Smoke Exposures
Secondhand smoke exposure (SHSe) is one of the most common and potentially modifiable environmental triggers for asthma. Financial incentivization may serve as an effective modality to reduce SHSe among pediatric asthmatics with…
- Conditions
- Asthma, Incentives, Tobacco Smoking
- Trial name
- NCT03099811
- Testing
- Incentive plan, Smoking cessation
- Where
- United States
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Depressive Disorder, Anxiety Disorders
Transdiagnostic Behavioral Activation Therapy for Youth Anxiety and Depression
Psychological therapies for depression have demonstrated efficacy, but outcomes are still unsatisfactory, especially in cases with high comorbidity.
- Trial name
- NCT01829100
- Testing
- Group Behavioral Activation Therapy (GBAT)
- Where
- United States
- Volunteers
- 895 people, healthy volunteers welcome
- Sponsor
- Rutgers University
Second Hand Smoke Exposure
The Protective Role of the Nose During Acute Exposure to Passive Smoking.
The aim of this study was to compare the acute effects of second hand smoke exposure between nasal and oral breathing and to assess the potential protective role of the nose during acute exposure, in exposure conditions similar…
- Trial name
- NCT01988467
- Testing
- exposure to second hand smoking
- Where
- Greece
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Hellenic Anticancer Society
Tobacco Use Disorder
Low Nicotine Content Cigarettes in Vulnerable Populations: Opioid Use Disorder
Prevalence of smoking among individuals with opioid use disorder (OUD) is six-fold that of the general US adult population. The mortality rate of opioid-dependent smokers is four times that of opioid-dependent nonsmokers, and…
- Trial name
- NCT04092101
- Testing
- Cigarettes with varying nicotine content, E-Cigarettes
- Where
- 2 sites in United States
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Sexually Transmitted Diseases, Safe Sex
P3 (Prepared, Protected, emPowered)
P3 (Prepared, Protected, emPowered) is an interactive smartphone app for HIV-uninfected YMSM and YTW that utilizes social networking and game-based mechanics as well as a comprehensive understanding of what constitutes "best…
- Conditions
- Sexually Transmitted Diseases, Safe Sex, Adherence, Medication
- Trial name
- P3 (NCT03320512)
- Testing
- P3, P3+, Control
- Where
- 9 sites in United States
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Measles, Varicella
Safety and Immunogenicity of Measles Vaccine, Varicella Vaccine and Hepatitis-A Vaccine
This trial will evaluate the safety and immunogenicity of: i) measles vaccine (CAM-70) after primary dose at 6 months (MV1) and booster vaccination at 12 months (MV2); ii) a single dose of varicella vaccination at 18 months; and…
- Conditions
- Measles, Varicella, Hepatitis A
- Trial name
- MV/VV/Hep-AV (NCT03330171)
- Testing
- Measles vaccine, Hepatitis-A vaccine, Varicella vaccine
- Where
- South Africa
- Volunteers
- 278 people, healthy volunteers welcome
- Sponsor
- University of Witwatersrand, South Africa
Human Immunodeficiency Virus (HIV)
Phase II Safety and Acceptability of an Investigational Injectable Product, TMC278LA, for Pre-Exposure Prophylaxis
This is a multi-site, double-blinded, two-arm, two:one, randomized, trial comparing the safety of an intramuscular (IM) injection of TMC278 LA to a placebo given once every eight weeks over a 40 week period among sexually active…
- Trial name
- TMC278LA (NCT02165202)
- Testing
- Rilpivirine
- Where
- 4 sites in United States, South Africa and 1 more
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- PATH
Effect of High Altitude
Effect of High Altitude Exposure, Acclimatization and Re-exposure on Psychomotor Performance in Lowlanders
Prospective interventional trial in lowlanders evaluating the effect of acute exposure, acclimatization and re-exposure to high altitude on psychomotor vigilance to measure sustained attention.
- Trial name
- NCT02731456
- Testing
- altitude exposure
- Where
- Canada
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Marc Poulin
Cardiovascular Effects
Diesel Exhaust and Vascular Function
Double-blind, sham- and placebo-controlled randomized study of effects of freshly-generated diluted diesel exhaust inhalation on vascular function.
- Trial name
- CVDTRAP4 (NCT01508637)
- Testing
- Diesel Exhaust, Filtered Air, Terazosin
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Washington
Dietary Carcinogenesis
Phase 2 Reduction of Dietary Mycotoxin Exposure by ACCS100"
The primary purpose of the study is to evaluate the effectiveness of a naturally occurring clay substance (ACCS100) in reducing harmful effects of aflatoxin exposure (a carcinogen) and fumonisin (a cancer promoter).
- Trial name
- RDMEACCS100 (NCT01677195)
- Testing
- ACCS100
- Where
- United States
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- Texas Enterosorbents Incorporated
Bone Regeneration
Comparative Study of Three Collagen Membranes: 1 Non-cross-linked and 2 Cross-linked
This study is being done to compare how quickly three different types of collagen membranes break down when they are exposed to the mouth.
- Trial name
- NCT06944639
- Testing
- Membrane Jason MB GmbH Non-cross-linked (NCL), Membrane BioMend Extend Glutaraldehyde cross-linked, Membrane OSSIX Agile Ribose cross-linked (RCL)
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Andrea Ravida
Myopia, Light; Therapy, Complications
Optimizing Light Exposure for Myopia Prevention and Control (LightSPAN)
The goal of this clinical trial is to evaluate whether the optimization of daily exposure to light in primary school children can lead to better myopia prevention and control.
- Conditions
- Myopia, Light; Therapy, Complications, Myopia Progression, Short-Sighted
- Trial name
- LightSPAN (NCT06631339)
- Testing
- Light Intervention, Digital Intervention, Control Group
- Where
- 5 sites in Singapore
- Volunteers
- 396 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Aflatoxicosis
Evaluation of ACCS100 to Reduce Aflatoxin Exposure in Kenya
The purpose of this study is to pilot test the effectiveness, acceptability, and palatability of ACCS100 in a high-risk Kenyan population.
- Trial name
- ACCS100 (NCT02188953)
- Testing
- ACCS100
- Where
- Kenya
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Kenya Medical Research Institute
Passive Smoking, Tobacco Smoke Pollution
Educational Models for Tobacco Exposure Awareness
This is a randomized controlled trial comparing the effects of peer education and traditional education on increasing knowledge and awareness of secondhand and thirdhand tobacco smoke exposure among geriatric care program…
- Conditions
- Passive Smoking, Tobacco Smoke Pollution, Health Education, Peer Group Guidance
- Trial name
- NCT07473245
- Testing
- Peer Education, traditional education
- Where
- Turkey (Türkiye)
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Dietary Exposure, Metabolic Disturbance
Influence of Tart Cherry Juice Intervention on Vascular Function
Diets containing fruit rich in anthocyanins have been shown (in meta-analyses) to be beneficial for health, but intervention trials have shown inconsistent results.
- Trial name
- NCT04840160
- Testing
- Cherry juice
- Where
- United Kingdom
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Sound Exposure, Exercise Performance
Effect of High-Level Headphone Sound Exposure on Exercise Responses in Young Healthy Individuals
This study will investigate the effect of high-level headphone sound exposure on cardiorespiratory responses and perceived exertion during a submaximal treadmill exercise test in young healthy individuals.
- Trial name
- NCT07556666
- Testing
- High-Level Headphone Sound Exposure, No-Sound Headphone Condition
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Radiation Exposure
A Prospective Study of Radiation Exposure to Surgeons
The purpose of this study is to measure the amount of radiation over a specific period of time that Orthopaedic Surgeons are exposed to while using the mini c-arm fluoroscopy machine.
- Trial name
- NCT00378053
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Psychological Well Being, Healthy Volunteers
REVI Pilot Feasibility Trial in Long-Term Care
This pilot study evaluates the feasibility, safety, and acceptability of an immersive virtual reality (VR) intervention designed to promote psychological well-being in older adults living in a long-term care facility.
- Conditions
- Psychological Well Being, Healthy Volunteers, Aging, Long-Term Care
- Trial name
- REVI (NCT07742137)
- Testing
- Active IVR, Passive IVR
- Where
- Spain
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Universidad de Almeria
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