Clinical trials: Extremity
Lymphedema of Upper Limb
Novel MRI Techniques on Evaluation of Lymphedema
In this project, the investigators aim to investigate the imaging approaches for breast cancer-related secondary lymphedema. The clinical study aims to optimize the conventional MRI methods for mapping lymphedema and assess the…
- Trial name
- NCT05804643
- Testing
- Diffusion magnetic resonance imaging
- Where
- Taiwan
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Athletic Injuries, Sports Injury Prevention
Evaluation of Injury Risk Factors and Effects of Individualized Exercise Program in Basketball and Volleyball Athletes
This study aims to identify injury risk factors using a clinical/functional test battery in university basketball and volleyball athletes, to develop individualized exercise prescriptions for athletes scoring below established…
- Conditions
- Athletic Injuries, Sports Injury Prevention, Musculoskeletal Injury
- Trial name
- IRISPORT (NCT07521215)
- Testing
- Test-Specific Individualized Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Upper Extremity Impairments, Cerebral Palsy (CP)
Obi Medical Robot: Evaluating Effectiveness Related to Usability
This mixed-methods usability study evaluates the effectiveness of the Obi Gen 3 robotic feeding device in meeting user needs among providers, caregivers, and patients.
- Conditions
- Upper Extremity Impairments, Cerebral Palsy (CP), ALS - Amyotrophic Lateral Sclerosis, Rett Syndrome
- Trial name
- NCT07151950
- Testing
- One-week trial of Obi Medical device, which provides robotic assistance with feeding to persons with upper extremity impairments who are unable to self-feed in the traditional manner using utensils
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Desin LLC
Soft Tissue Sarcoma of the Lower Extremity, Bone Tumor of the Lower Extremity
Prehabilitation in Childhood Soft Tissue or Bone Sarcomas
This study aims to investigate the feasibility of a prehabilitative training intervention. The intervention includes specific strength and balance exercises during neoadjuvant chemotherapy with children and adolescents diagnosed…
- Conditions
- Soft Tissue Sarcoma of the Lower Extremity, Bone Tumor of the Lower Extremity, Childhood and Adolescent Cancer
- Trial name
- Prehab4Kids (NCT06743958)
- Testing
- Exercise intervention
- Where
- 2 sites in Germany
- Volunteers
- 16 people
- Sponsor
- Technical University of Munich
Upper Extremity Dysfunction, Lower Extremity Problem
Decision Aids Upper and Lower Extremity
This study aims to assess differences in choice of treatment (and the rationale behind it), physical function, pain intensity, satisfaction, and decision regret between orthopedic patients who review a decision aid during their…
- Trial name
- NCT03643978
- Testing
- Decision aid
- Where
- 6 sites in United States
- Volunteers
- 168 people
- Sponsor
- University of Texas at Austin
Stroke
New Tool to Enhance Post-stroke Upper Extremity Disability
Individuals with low socioeconomic status (SES) are more likely to have a stroke, more disabled at 3 months, and less likely to be independently ambulatory.
- Trial name
- NCT05277389
- Testing
- START - Startle Adjuvant Rehabilitation Therapy
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Arizona State University
Diabetes Mellitus
Assessing Diabetic Foot Ulcer Microcirculation With High-frequency Contrast Enhanced Ultrasound
The objective of this observational study is to investigate and validate the utility of high-frame-rate ultrasound imaging technology for dynamic observation of the blood perfusion process at the site of ulcer wounds in…
- Trial name
- NCT06309082
- Testing
- Amputation, Debridement
- Where
- China
- Volunteers
- 100 people
- Sponsor
- First Affiliated Hospital of Wenzhou Medical University
Infection
"Domino" Therapy Treat the Infection Around the Prosthesis After the Limb Salvage Surgery of Bone Tumor
Tumor resection and prosthetic replacement have become the treatments of choice for malignant bone tumors. Infections are the main cause of failure of limb salvage surgeries.
- Trial name
- NCT05255185
- Testing
- domino therapy
- Where
- China
- Volunteers
- 14 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Stroke
Enhanced Treadmill Gait Training With Lower Limb Support After Stroke
This series of single case studies aims to test the feasibility and acceptability of an enhanced treadmill system for the recovery of gait function in stroke survivors.
- Trial name
- ENTRES (NCT03348215)
- Testing
- Enhanced Treadmill Training
- Where
- United Kingdom
- Volunteers
- 21 people
- Sponsor
- University of Strathclyde
Orthopaedic Surgery, Upper Extremity
The Effect of Pain Neuroscience Education on Preoperative Anxiety and Postoperative Recovery in Patients Scheduled for Orthopedic Surgery
This study aimed to investigate the effects of preoperative PNE on preoperative anxiety, pain-related beliefs, and postoperative functional outcomes in patients undergoing upper extremity orthopedic surgery.
- Trial name
- NCT07107360
- Testing
- Pain Neuroscience Education, Conventional preoperative education
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people
- Sponsor
- Atlas University
Bone Fracture
IN Sub-Dissociative Ketamine vs IN Fentanyl
This single center, randomized control, double blind trial will prospectively examine the feasibility of intranasal, sub-dissociative (IN) ketamine versus intranasal fentanyl for pain control in the pediatric emergency department…
- Trial name
- NCT02521415
- Testing
- ketamine, fentanyl, ibuprofen or acetaminophen
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Wake Forest University Health Sciences
Spinal Cord Injuries
Clinical Investigation on Feasibility and Usability of the ABLE Exoskeleton Device for Individuals With Spinal Cord Injury to Perform Skills for Home and Community Environments
The loss of the ability to walk and the associated restriction of mobility presents a major challenge to people with spinal cord injury in an everyday environment designed for pedestrians.
- Trial name
- NCT05643313
- Testing
- ABLE Exoskeleton
- Where
- 2 sites in Germany, Spain
- Volunteers
- 10 people
- Sponsor
- ABLE Human Motion S.L.
Knee Osteoarthritis
Effects of Gait Retraining on Lower Extremity Biomechanics
The purpose of this proposed study is to investigate both the acute and chronic response of frontal plane knee moment after gait retraining and to assess the effects on the biomechanics of the contralateral side.
- Trial name
- NCT03663790
- Testing
- Foot Progression, Trunk Lean
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- George Mason University
Critical Limb Ischemia
Efficacy and Safety of AMG0001 in Subjects With Critical Limb Ischemia
Study to Evaluate the Efficacy and Safety of AMG0001 in Subjects with Critical Limb Ischemia.
- Trial name
- AGILITY (NCT02144610)
- Testing
- HGF Plasmid (AMG0001)
- Where
- 60 sites in United States, Belgium and 9 more
- Volunteers
- 46 people
- Sponsor
- AnGes USA, Inc.
Chronic Limb-Threatening Ischemia
Peripheral Bypass Trial for Completion Control
The goal of the study is to identify and validate flow measurement and ultrasound images in patients undergoing vein bypass surgery below-knee and above ankle
- Trial name
- PATENT (NCT06264843)
- Testing
- MiraQ with Transit-Time Flow Measurement (TTFM) and L15 High Frequency Ultrasound (HFUS) probes
- Where
- United States
- Volunteers
- 450 people
- Sponsor
- Medistim ASA
Leg Length Inequality, Cerebral Palsy
Spine Biomechanics During Gait Following Lower Extremity Treatment in Different Patient Groups
Measuring spine dynamics is a necessity in order to better understand gait deviations throughout the whole body and to evaluate treatment effects on spinal movement during gait.
- Trial name
- NCT01803243
- Testing
- Ankle foot orthosis, Shoe insole, Modified shoe with sole lift
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- University Children's Hospital Basel
Bone Fracture
Enhancement of Bone Regeneration and Healing in the Extremities by the Use of Autologous BonoFill-II
The purpose of this clinical study is to evaluate the safety and the efficacy of BonoFill-II as an autologous bone-regenerating graft in the reconstruction of deficient bone in two clinical indications: 1.
- Trial name
- NCT03024008
- Testing
- BonoFill-II
- Where
- 6 sites in Israel
- Volunteers
- 40 people
- Sponsor
- BonusBio Group Ltd
Cervical Radiculopathy
Does Low-does Cervical Epidural Lidocaine Cause Transient Weakness?
"Does low-does cervical epidural lidocaine cause transient weakness?"
- Trial name
- NCT03382925
- Testing
- cervical interlaminar with lidocaine, cervical interlaminar with normal saline, Lidocaine
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Utah
Post Mastectomy Lymphedema
Kinesiology Taping Technique in Post-mastectomy Breast Cancer Related Lymphedema
Generally, Breast cancer related to lymphedema is commonly found in the female population after mastectomy. It has many complications which affects the normal functions of an individual and quality of life.
- Trial name
- NCT05178797
- Testing
- Kinesiology taping technique with exercise therapy, Compression decongestive therapy
- Where
- 2 sites in Pakistan
- Volunteers
- 50 people
- Sponsor
- Dow University of Health Sciences
Metastatic Urothelial Carcinoma, Unresectable Urothelial Carcinoma
Pemigatinib + Pembrolizumab vs Pemigatinib Alone vs Standard of Care for Urothelial Carcinoma (FIGHT-205)
The purpose of this study is to evaluate the safety and efficacy of pemigatinib plus pembrolizumab or pemigatinib alone versus the standard of care for participants with metastatic or unresectable urothelial carcinoma who are not…
- Trial name
- NCT04003610
- Testing
- Pemigatinib, Pembrolizumab, Gemcitabine
- Where
- 79 sites in United States, Austria and 14 more
- Volunteers
- 7 people
- Sponsor
- Incyte Corporation