Clinical trials: Extremity Injury
Spinal Cord Injuries
Technology Development for Physical Rehabilitation of Patients With Upper Extremity Motor Deficits (RePlay)
Injuries and disease processes that produce upper extremity deficits are devastating to patients and their families. One potential avenue to treat these neurological disorders is through the enhancement of neural plasticity…
- Trial name
- RePlay (NCT03621969)
- Testing
- Physical exam and medical history, Assessments, Patient Instruction and use of Device (RePlay)
- Where
- 2 sites in United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Dallas
Diabetes, Wound Infection
Tebipenem (SPR994) Tissue Penetration in Diabetic Patients With Wound Infections and Healthy Volunteers Via In Vivo Microdialysis
This study will determine the tissue penetration of a broad-spectrum orally bioavailable carbapenem, tebipenem pivoxil hydrobromide (SPR994) (Spero Therapeutics, Inc.), into the extracellular, interstitial fluid of soft tissue in…
- Conditions
- Diabetes, Wound Infection, ABSSSI, Healthy Volunteers
- Trial name
- NCT04919954
- Testing
- Tebipenem Pivoxil Hydrobromide
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Hartford Hospital
Patellofemoral Pain Syndrome, Exertional Lower Leg Pain
Prevention of Injuries by an Exercise Program - a RCT
Overuse injuries are a major concern for physical active individuals. Study hypothesis is that an exercise programme based on known intrinsic risk factors can prevent overuse injuries in soldiers undergoing basic military…
- Trial name
- NCT00348647
- Testing
- physical training program to prevent injuries
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Amager Hospital
Lower Extremity Problem
Injury Prevention for Female Lacrosse Athletes
In this pilot study the investigators are testing whether an injury prevention program will help improve quality of movement and decrease number of injuries in collegiate women's lacrosse athletes.
- Trial name
- NCT06255899
- Testing
- Education Program on Injury Prevention, Individualized Feedback + Education Program on Injury Prevention
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Bone Fracture
A Comparative Study Between Intrathecal Dexmedetomidine VS Ketamine With Intrathecal Bupivacaine in Orthopedic Lower Limb Surgeries.
Orthopedic anaesthesia and acute postoperative pain management, two anesthesiology subspecialties,are getting more credit for reducing hospital stays, promoting functional recovery and improving patient satisfaction.
- Trial name
- NCT05751304
- Testing
- Dexmedetomidine, Ketamine
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
for Upper Limb Soft Tissue Coverage
The Radial Forearm Flap In Reconstruction Of Upper Limb Injuries
The radial forearm flap is a very useful and versatile flap with a long vascular pedicle and a thin, pliable skin. It's used in reconstruction of the mutilated hand as a reverse pedicled flap.
- Trial name
- NCT06319586
- Testing
- Radial Forearm Flap
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sohag University
Upper Extremity Fractures, Analgesia Post Fracture
Oral Morphine Versus Ibuprofen
Children 5-17 years of age who have sustained a non-operative distal forearm (radius and/or ulna) or clavicular fracture will be randomized to receive either ibuprofen or oral morphine as needed for pain relief for the first 24…
- Trial name
- NCT01690780
- Testing
- Oral morphine, Ibuprofen
- Where
- Canada
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Naveen Poonai
Hand Injuries, Wrist Injuries
Study of A Long Lasting Local Anesthestic for Hand, Wrist or Finger Surgery
The purpose of this study is to compare Exparel, a new, long-lasting numbing medication and a shorter-acting nerve block to a traditional single-shot nerve block in patients having hand, wrist or finger surgery.
- Conditions
- Hand Injuries, Wrist Injuries, Finger Injuries
- Trial name
- NCT02058303
- Testing
- Exparel Forearm block, Bupivacaine supraclavicular block
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Jose Soberon, MD
Fractures, Bone
Cast Art for Kids With Extremity Fractures
The goal of this clinical trial is to compare casts with cast art versus those without art in children who sustain a fracture of the extremity.
- Trial name
- CAKE POP (NCT06990555)
- Testing
- Neutral White Cast, Color Wrapped Cast, Cast with Cast Art
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, Portsmouth
Stroke, Ischemic, Stroke Hemorrhagic
Exploring Accessible Beauty for Individuals With Upper Extremity Deficits
The purpose of this study is to investigate the accessibility of beauty products for individuals with upper extremity disabilities.
- Conditions
- Stroke, Ischemic, Stroke Hemorrhagic, Stroke (CVA) or TIA, Stroke, Acute
- Trial name
- NCT05945784
- Testing
- Use of Rare Beauty makeup products
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Casa Colina Hospital and Centers for Healthcare
Sports Injury, Injury Prevention in Sports
Role of Stepping and BOSU Ball Training in Enhancing Postural Balance and Performance of Badminton Players
Influence of Square Stepping and BOSU Ball Exercise on Lower Extremity Balance and Strength in Badminton Players: An Expanded Explanation for Patients, Families, and Health Care Providers Badminton is a dynamic and physically…
- Trial name
- NCT07353866
- Testing
- Square stepping + BOSU ball exercise, BOSU ball and Shadow training, Conventional Training
- Where
- Malaysia
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- INTI International University
Amputation, Amputation; Traumatic, Leg, Lower
Clinical Outcomes With Passive MPKs vs. Powered Prosthetic Knees
The goal of this proposed project is to gather community-based data from the K4-level Transfemoral Amputee (TFA) population to aid in evidence-based prescription of powered prosthetic knees (i.e., choosing the right device to…
- Conditions
- Amputation, Amputation; Traumatic, Leg, Lower, Limb; Absence, Congenital, Lower, Prosthesis User
- Trial name
- NCT05267639
- Testing
- Power Knee
- Where
- 2 sites in United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Liberating Technologies, Inc.
Neuropathic Pain
The Effect of Neuropathic Pain in Patients With Combat-related Extremity Injury
It has been suggested that veterans with chronic pain might be at increased risk for the development of depression, anxiety and post-traumatic stress disorder.
- Trial name
- NCT04674631
- Testing
- The effect of neuropathic pain on quality of life, depression and sleep quality
- Where
- Turkey (Türkiye)
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Range of Motion, Neuromuscular Signs and Symptoms
Contralateral Neurodynamic Mobilisation Improves Hamstring Flexibility.
The goal of this clinical trial is to investigate whether single limb neurodynamic mobilizations increase active knee extension (AKE) range of motion (ROM) of the contralateral limb.
- Conditions
- Range of Motion, Neuromuscular Signs and Symptoms, Wounds and Injury
- Trial name
- NCT07648732
- Testing
- Neurodynamic Hamstring Mobilisation
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Salford
Hyperthermia, Weather; Heat
Mitigating Heat-induced Physiological Strain and Discomfort in Older Adults Via Lower Limb Immersion and Neck Cooling
The incidence and severity of hot weather and extreme heat events (heat waves) is increasing. As such, there is an urgent need to develop heat-alleviation strategies that can provide targeted protection for older adults who are…
- Conditions
- Hyperthermia, Weather; Heat, Heat Stress, Heat Syncope
- Trial name
- NCT05601713
- Testing
- No cooling (control), Lower limb immersion, Lower limb immersion + neck cooling
- Where
- Canada
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Athletic Injuries, Knee Injuries
Analysis of Balance and Functional Hop Tests in Athletes With Lower Extremity Injuries by Dual Task Study
Functional Hop tests and balance measurements are frequently used to decide on returning to sports after lower extremity injuries.
- Conditions
- Athletic Injuries, Knee Injuries, Ankle Injuries, Hip Injuries
- Trial name
- NCT05484778
- Testing
- Dual tasking paradigm
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Ischemia Reperfusion Injury, Peripheral Artery Disease
Vitamin B6 on Exercise Pressor Reflex on Leg Ischemia-reperfusion
In this study, we are trying to see if vitamin B6 can minimize the amplified blood pressure response to exercise following ischemia-reperfusion injury.
- Trial name
- NCT06369350
- Testing
- Vitamin B6 25 MG, Vitamin B6 50 MG, Vitamin B6 100 MG
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Lower Limb Amputation Above Knee (Injury), Lower Limb Amputation Below Knee (Injury)
Virtual Reality Treatment for Phantom Limb Pain
Patients with limb amputations experience the sensation of the missing extremity, which is sometimes coupled with a persistent and debilitating pain in the missing limb, a condition known as phantom limb pain (PLP).
- Conditions
- Lower Limb Amputation Above Knee (Injury), Lower Limb Amputation Below Knee (Injury), Phantom Limb Pain
- Trial name
- NCT03338842
- Testing
- Distractor and Lower limb VR
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Wound Healing
Compression and CO2 Laser for Leg Wounds
The purpose of this study is to determine the efficacy and safety of compression bandaging with fractional ablative carbon dioxide laser (FACL) compared to compression and standard dressings alone for healing of post-operative…
- Trial name
- NCT04198454
- Testing
- Compression bandages, Standard wound dressings, Fractional ablative carbon dioxide laser
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Upper Limb; Injury, Superficial, Multiple
Effectiveness of Laboral Kinesiotherapy in Prevention of Upper Limb Musculoskeletal Disorders
ABSTRACT Work-related musculoskeletal disorders are seen as a public health problem, and can often lead to temporary or permanent incapacity to work.
- Trial name
- NCT04047056
- Testing
- Labor Kinesiotherapy
- Where
- Brazil
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo