Clinical trials: Extremity Injury
Wrist Injury, Hand and Upper Limb Trauma
Virtual Reality-based Rehabilitation for Traumatic Hand and Wrist Injuries
This randomized controlled trial aims to evaluate the effectiveness of immersive virtual reality (VR)-based Action Observation Therapy (AOT) as an adjunct to conventional rehabilitation in patients with traumatic wrist and hand…
- Conditions
- Wrist Injury, Hand and Upper Limb Trauma, Hand and Forearm Trauma, Muskuloskeletal Diseases
- Trial name
- AOT-VR-HAND (NCT07633769)
- Testing
- Immersive Virtual Reality Action Observation Therapy, Conventional Rehabilitation
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- University of Malaga
Nonunion Fracture
Treatment of Nonunion of Limb Fracture With Human Amniotic Epithelial Cells（hAECs）
The purpose of this study is to evaluate the efficacy and safety of human amniotic epithelial cells transplant in nonunion of limb fracture patients.
- Trial name
- NCT03031509
- Testing
- Human Amniotic Epithelial Cells, debridement
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Shanghai East Hospital
Soft Tissue Injuries
Study to Determine if Shock Wave Therapy Applied to Traumatic Wounds of the Extremity Improves Healing Time
The purpose of this study is to determine if adding shock wave therapy to standard-of-care wound treatment for traumatic extremity wounds helps them heal faster.
- Trial name
- CWI (NCT00486733)
- Testing
- DermaGold
- Where
- United States
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- Walter Reed Army Medical Center
Pain, Muscle, Pain, Acute
Arnica and the Management of Pain in Acute Musculoskeletal Extremity Injuries
In the Emergency Department, there is no standard of care for pain medication distribution for children with an acute musculoskeletal injury when there is no fracture present.
- Trial name
- NCT05283434
- Testing
- Arnica
- Where
- 2 sites in United States
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- Children's Hospitals and Clinics of Minnesota
Distal Radius Fracture
Bier's Block Versus Systemic Analgesia
Background: There are three methods for procedural sedation in upper extremity traumas; systemic, regional and local anesthesia. There is controversy in the literature regarding the method of choice for this purpose.
- Trial name
- NCT03349216
- Testing
- Intravenous Regional Anesthesia, Systemic Analgesia
- Where
- Iran
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Pain, Persistent Pain
Is Low-load Resistance Training With Blood Flow Restriction Feasible During Rehabilitation of Military Personnel With Lower Limb Injuries? Phase One RCT.
Pain can be one of the primary limiting factors to progress following musculoskeletal injury and may be caused by trauma or degenerative changes.
- Conditions
- Pain, Persistent Pain, Musculoskeletal Pain
- Trial name
- LIMITLESS (NCT06621914)
- Testing
- BFR 80, BFR40
- Where
- United Kingdom
- Volunteers
- 28 people
- Sponsor
- Defence Medical Rehabilitation Centre, UK
Lower Extremity Fracture
Suture Versus Staples for Wound Closure in Orthopaedic Trauma Surgery
This pilot study is designed to assess the feasibility of comparing skin closure methods - sutures versus staples - and subsequent rates of surgical site infection following open reduction and internal fixation surgery for…
- Trial name
- SvS (NCT06586814)
- Testing
- Suture, Staple
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Southern California
Single Chronic Wound, Lower Limb Wound
Telemonitoring of Chronic Wound Patients Using MyDerm, a Digital Solution: Feasibility Study
The aim of this study is to assess the feasibility of integrating myDerm for remote monitoring of chronic wounds into everyday practice, for patients over 18 years of age suffering from a single chronic wound of the lower limb…
- Trial name
- PIXAPROM (NCT06704087)
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Pixacare
Pain Management, Perioperative Analgesia
From Battlefield to Recovery: Continuous Regional Anaesthesia for War-Related Lower Limb Trauma
To compare the effectiveness of continuous regional anaesthesia with standard pain management strategies for the treatment of acute pain in patients with war-related lower limb trauma.
- Conditions
- Pain Management, Perioperative Analgesia, War-Related Injuries
- Trial name
- CRA-WAR-LIMB S (NCT07474506)
- Where
- Ukraine
- Volunteers
- 150 people
- Sponsor
- Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans)
Brain Injuries, Brain Injuries, Traumatic
Visual Feedback in Lower Limb Rehabilitation
Severe Acquired Brain Injury (sABI) is defined as "an encephalic impairment that occurs after birth and is not related to a congenital or degenerative disease.
- Conditions
- Brain Injuries, Brain Injuries, Traumatic, Brain Injuries, Vascular
- Trial name
- NCT05179330
- Testing
- OMEGO®
- Where
- Italy
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Spinal Cord Injuries
Assessment of a Robotic Exoskeleton for Upper Limb Rehabilitation
Rehabilitation robotics has the potential to facilitate rehabilitation at home and empower people with spinal injuries to self-manage increasing their independence and improving their quality of life.
- Trial name
- Exo4UL (NCT05615766)
- Testing
- Experimental: Device Intervention
- Where
- 2 sites in United Kingdom
- Volunteers
- 9 people
- Sponsor
- University of Liverpool
Distal Limbs Bones Fractures
Assessment of Distal Limbs Fractures With Cone-Beam CT Newtom 5G
ConeBeam scanner (CBCT) is a widely technique used for dental and maxillofacial imaging. Patients can be set up in a sitting or a laying position in the, Newtom 5G CBCT allowing for an analysis of the distal appendicular…
- Trial name
- FRADICOBE (NCT01796600)
- Testing
- The patients will have a conventional scanner, a reference examination, and a cone-beam scanner Newtom 5G just after the conventional scanner
- Where
- France
- Volunteers
- 43 people
- Sponsor
- Hospices Civils de Lyon
Ankle Sprains, Patellofemoral Pain Syndrome
Distinct Directional Postural Stability Deficits Across Lower Limb Musculoskeletal Disorders
Lateral ankle sprain (LAS) and patellofemoral pain syndrome (PFPS) are common musculoskeletal conditions associated with postural instability.
- Trial name
- LAS-PFPS (NCT07508163)
- Testing
- diagnosis of APSI, MLSI, OASI
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cairo University
Hip Fractures, Lower Extremity Fracture
Can Mobility Technicians Provide Value to Hospitalized Patients?
The specific aim of this study is to determine the impact of the addition of a dedicated mobility technician to the care team on specialty specific outcomes for patients recovering from surgical treatment for a hip or lower…
- Conditions
- Hip Fractures, Lower Extremity Fracture, Lung Transplant
- Trial name
- NCT03874767
- Testing
- Patient Mobility
- Where
- United States
- Sponsor
- Vanderbilt University Medical Center
Anterior Cruciate Ligament Rupture
The Effect of Subtalar Joint Antipronation Taping on the Dynamic Knee Valgus in Female Volleyball Players with Low Medial Arch
This study aims to investigate the biomechanical mechanisms of dynamic knee valgus and the impact of subtalar pronation, particularly due to decreased medial longitudinal arch, on knee injury risk, highlighting the importance of…
- Trial name
- NCT06752109
- Testing
- Antipronation Taping
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Ankara Yildirim Beyazıt University
Phantom Limb Pain, Amputation
Phantom Limb Pain in Amputees After the 2023 Türkiye Earthquake
The goal of this observational study is to investigate the prevalence and persistence of phantom limb pain (PLP) among amputees who experienced limb loss due to injuries sustained during the 2023 Türkiye earthquake.
- Conditions
- Phantom Limb Pain, Amputation, Pain Management, Earthquake
- Trial name
- NCT06617728
- Testing
- Intervention 1: Regional Analgesia, Intervention 2: Intravenous (IV) Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- Mesut Bakır
Neuropathic Pain, Amputation, Traumatic
Postamputation Pain: Peripheral Mechanisms
Stump and phantom pain after amputation are common, but the responsible mechanisms are still not clarified. It has been suggested that phantom limb pain can be reduced by regional anaesthesia and in several recent studies, pain…
- Conditions
- Neuropathic Pain, Amputation, Traumatic, Nerve Block, Phantom Limb Pain
- Trial name
- NCT03317600
- Testing
- Lidocaine
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- Danish Pain Research Center
Lower Limb; Sprain (Strain), Lower Limb Fracture
Implementation of an App-based Walking Aid Skills Training Program
Walking aids (WA), such as crutches, canes, and walkers allow individuals to move independently after lower body impairment. Improper WA use may lead to upper body discomfort, pain, or injury.
- Conditions
- Lower Limb; Sprain (Strain), Lower Limb Fracture, Stroke, Multiple Sclerosis
- Trial name
- NCT05347875
- Testing
- Walking aid skills app, Breathing skills app
- Where
- 2 sites in Canada
- Volunteers
- 52 people
- Sponsor
- University of Calgary
Fracture Arm, Fracture Closed of Lower End of Forearm, Unspecified
A Clinical Trial on the Use of Lidocaine Infusion During Surgery for Pediatric Upper Extremity Fractures and Its Impact on Total Perioperative Opioid Requirements
This study is a prospective, randomized, double-blind clinical trial evaluating whether intraoperative intravenous lidocaine infusion (IVLI) reduces opioid requirements and improves postoperative pain control in children…
- Conditions
- Fracture Arm, Fracture Closed of Lower End of Forearm, Unspecified, Fracture Elbow, Fracture Fixation
- Trial name
- NCT07552766
- Testing
- Lidocaine Infusion, Standard of Care (SOC)
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Nemours Children's Clinic
Peripheral Nerve Injury at Forearm Level (Diagnosis)
Effects of Motor Learning After Upper Limb Peripheral Nerve Injury
The outcome of peripheral nerve injury is related to age, level of injury, the injured nerve, the severity of injury, and the timing and the type of surgery interventions.
- Trial name
- NCT04087577
- Testing
- conventional physical therapy, mirror therapy
- Where
- 2 sites in Taiwan
- Volunteers
- 8 people
- Sponsor
- Chang Gung Memorial Hospital