Clinical trials: Eye
Myopia, Hyperopia
A Prospective Safety and Effectiveness Study of the 500 Hz Technolas Perfect Vision Excimer Laser Using LASIK
This clinical study has been planned to evaluate the safety and effectiveness of a common treatment algorithms (Proscan) using 500 Hz laser repetition rate.
- Trial name
- NCT02071576
- Testing
- Proscan
- Where
- China
- Volunteers
- 42 people
- Sponsor
- Technolas Perfect Vision GmbH
Refractive Error
ACUVUE® OASYS® 1-DAY vs DAILIES TOTAL1®
The purpose of this study is to compare the lens fit characteristics, specifically lens centration, of ACUVUE® OASYS® 1-DAY (AO1D) contact lenses and DAILIES TOTAL1® (DT1) contact lenses.
- Trial name
- NCT02750813
- Testing
- Delefilcon A contact lenses, Senofilcon A contact lenses
- Where
- United States
- Volunteers
- 252 people
- Sponsor
- Alcon, a Novartis Company
Myopia
Development of a New Device and Method to Assess the Degree of Myopia and/or Astigmatism in Myopic People
The purpose of this clinical investigation is to check whether the new device can correctly measure a person's degree of myopia and astigmatism.
- Trial name
- MDSW_DiVA2Rx (NCT07297810)
- Testing
- Optical correction values obtained with investigational device and visual acuity, Optical correction values obtained with an autorefractometer and visual acuity, Optical correction values obtained with a phoropter and visual acuity
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Essilor International
Subfoveal Choroidal Neovascularization (CNV), Secondary to Age-related Macular Degeneration (AMD)
Safety and Tolerability of Ranibizumab in Patients With Subfoveal Choroidal Neovascularization Secondary to Age-related Macular Degeneration
This extension study will investigate the long-term safety and tolerability of multiple intravitreal injections of ranibizumab administered to patients with subfoveal choroidal neovascularization secondary to age-related macular…
- Trial name
- NCT00504959
- Testing
- ranibizumab
- Where
- 36 sites in Australia, Belgium and 8 more
- Volunteers
- 234 people
- Sponsor
- Novartis
Chronic Graft-versus-host Disease
Safety and Efficacy Study of R932348 Ophthalmic Solution in Chronic Ocular Graft Versus Host Disease Patients(DROPS-2)
To assess the efficacy of R348 Ophthalmic Solutions administered for 12 weeks to subjects evaluated by objective and subjective measures.
- Trial name
- DROPS-2 (NCT02040623)
- Testing
- R348 Ophthalmic Solution, 0.2%, R348 Ophthalmic Solution, 0.5%
- Where
- 2 sites in United States
- Volunteers
- 35 people
- Sponsor
- Rigel Pharmaceuticals
Skin Health
A Clinical Trial to Evaluate the Effects of a Skin Balm on the Appearance of the Eye Area
This virtual single-group clinical trial aims to evaluate the effects of the Sahajan Golden Glow Balm on the health and appearance of the skin in the periorbital area over a period of 6 weeks.
- Trial name
- NCT06452810
- Testing
- Experimental: Sahajan Golden Glow Balm
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Sahajan
Sjogren's Syndrome
Study to Assess Safety and Efficacy of Filgotinib, Lanraplenib and Tirabrutinib in Adults With Active Sjogren's Syndrome
The primary objective of this study is to assess the efficacy of filgotinib, lanraplenib, and tirabrutinib in adults with active Sjogren's Syndrome (SjS).
- Trial name
- NCT03100942
- Testing
- Lanraplenib, Filgotinib, Tirabrutinib
- Where
- 53 sites in United States, Poland and 2 more
- Volunteers
- 152 people
- Sponsor
- Gilead Sciences
Cataract, Presbyopia
The Visual Performances of a Progressive Multifocal Intraocular Lens With Extended Depth of Focus
The purpose of this observational, non-controlled, multicenter trial with a retrospective design is to evaluate the visual performance of one cohort of patients who received the EDOF MINI WELL® intraocular lenses following…
- Trial name
- NCT02740010
- Testing
- EDOF Mini WELL Ready IOL
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- SIFI SpA
Bacterial Infections, Eye Infections
Study of AzaSite Versus Vigamox Concentrations in the Conjunctiva and Aqueous Humor in Subjects Undergoing Routine Cataract Surgery
The purpose of this study is to evaluate the drug concentrations in the conjunctiva and aqueous humor of AzaSite™ compared to Vigamox® in subjects undergoing routine cataract surgery
- Conditions
- Bacterial Infections, Eye Infections, Cataract Extraction
- Trial name
- NCT00575380
- Testing
- AzaSite Eye Drops, Vigamox Eye Drops
- Where
- 13 sites in United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Cataract
A Study to Evaluate Efficacy and Safety of MELT-300 for Procedural Sedation in Subjects Undergoing Cataract Extraction With Lens Replacement (CELR)
The goal of this clinical trial is to learn if MELT-300 works on procedural sedation in adult participants undergoing cataract extraction with lens replacement (CELR). It will also learn about the safety of MELT-300.
- Trial name
- NCT06383273
- Testing
- MELT-300 sublingual tablet, Midalozam sublingual tablet
- Where
- 12 sites in United States
- Volunteers
- 528 people
- Sponsor
- Melt Pharmaceuticals
Myopia, Dry Eye
Effect of Contact Lenses on Tear Osmolarity in a Controlled Low Humidity Chamber
The purpose of this study is to evaluate two different types of contact lenses and their effect on dry eyes when compared to wearing glasses in a controlled, low humidity chamber.
- Trial name
- NCT01482312
- Testing
- lotrafilcon A contact lenses, comfilcon A contact lenses, Glasses
- Where
- Canada
- Volunteers
- 29 people
- Sponsor
- CIBA VISION
Myopia
Performance Comparison Between Comfilcon A and Senofilcon C Lenses
The aim of this study is to determine the clinical performance of comfilcon A in comparison to senofilcon C.
- Trial name
- NCT02920957
- Testing
- comfilcon A, senofilcon C
- Where
- 5 sites in United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Aphakia
Clinical Evaluation of the FluidVision Accommodating Intraocular Lens (AIOL)
The purpose of this study is to evaluate the safety and effectiveness of an investigational IOL.
- Trial name
- NCT02049567
- Testing
- FluidVision AIOL, Cataract Surgery
- Where
- 8 sites in Germany, South Africa
- Volunteers
- 170 people
- Sponsor
- PowerVision
Dry Eye Syndromes
Efficacy and Safety Study for Ecabet Ophthalmic Solution for Treating Dry Eye Syndrome
The purpose of this study is to determine whether ecabet ophthalmic solution is an effective treatment for dry eye syndrome
- Trial name
- NCT00198536
- Testing
- Ecabet 2.83%, Ecabet 3.70%, Vehicle
- Where
- 3 sites in United States
- Volunteers
- 159 people
- Sponsor
- Bausch & Lomb Incorporated
Dry Eye Syndromes
3 Month Study of Alocross Versus Vismed in Adults With Dry Eye Disease Related to Keratitis or Keratoconjunctivitis
This study is a prospective, multicentre, parallel-group, active-controlled, non-inferiority study conducted in adult patients with moderate-to-severe dry eye disease (DED) related to keratitis or keratoconjunctivitis.
- Trial name
- ALHENA (NCT04685109)
- Testing
- Alocross 0.2% Unit Dose, Vismed
- Where
- 6 sites in France
- Volunteers
- 80 people
- Sponsor
- Santen SAS
Myopia, Myopia, Moderate
Software Refraction With Mobilerone Versus Retinoscopy
Software refraction in the mobilerone for myopia and astigmatism is a novel medical device for myopia adults and elder children with or without astigmatism.
- Conditions
- Myopia, Myopia, Moderate, Astigmatism
- Trial name
- SRMR (NCT06059521)
- Testing
- Software refraction with Eye Test Technology in a mobilerone, Retinoscopy
- Where
- 3 sites in China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Beijing Airdoc Technology Co., Ltd.
Allergic Conjunctivitis
Safety and Efficacy Study of AL-53817 and AL-78843 Ophthalmic Solutions for Allergic Conjunctivitis
The purpose of this study is to evaluate two investigational ophthalmic solutions for reduction in ocular redness in subjects with allergic conjunctivitis.
- Trial name
- NCT02079649
- Testing
- AL-53817 Ophthalmic Solution, 0.1%, AL-78843 Ophthalmic Solution, 0.03%, Dexamethasone Ophthalmic Suspension, 0.1%
- Volunteers
- 224 people
- Sponsor
- Alcon Research
Refractive Error
Formula Identification (FID) 114657 in Contact Lens Wearers
The purpose of this study is to evaluate the thickness of the pre-lens tear lipid layer after 2 hours of lens wear with use of FID 114657 compared to saline control.
- Trial name
- NCT02293538
- Testing
- FID 114657 eye drops (10 ml), Saline control eye drops (15 ml), Habitual contact lenses
- Volunteers
- 234 people
- Sponsor
- Alcon Research
Meibomian Gland Dysfunction
Evaluation of FID 114657 in Dry Eye Subjects
The primary objective of this study is to assess the overall Meibomian Gland Dysfunction Subject's preference for a particular product.
- Trial name
- NCT01079858
- Testing
- FID 114657 (ORB Preserved Ocular Emulsion)
- Volunteers
- 49 people
- Sponsor
- Alcon Research
Neuromyelitis Optica Spectrum Disorder, Transverse Myelitis
Central Pain Study for ABX-1431
This study will determine the safety and tolerability of ABX-1431 in patients with central pain when added on to background pain therapy.
- Conditions
- Neuromyelitis Optica Spectrum Disorder, Transverse Myelitis, Multiple Sclerosis, Longitudinally Extensive Transverse Myelitis
- Trial name
- NCT03138421
- Testing
- ABX-1431 HCl
- Where
- 2 sites in United Kingdom
- Volunteers
- 9 people
- Sponsor
- Abide Therapeutics
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.