Clinical trials: Eye
Strabismus, Regional Anesthesia Morbidity
Peribulbar Rocuronium in Adult Strabismus Surgery
This is a prospective randomized clinical study that will be carried on adult patients aged from 21-60 years and presented for strabismus surgery under peribulbar anesthesia.
- Conditions
- Strabismus, Regional Anesthesia Morbidity, Rocuronium
- Trial name
- NCT04821817
- Testing
- Normal saline, Rocuronium
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Tanta University
Trabeculectomy
Evaluation of Filtering Bleb After Glaucoma Surgery by AS-OCTA
When antihypertensive drugs or laser therapy can not reach the target intraocular pressure, trabeculectomy (TRAB) is still the standard surgical method for glaucoma.
- Trial name
- AS-OCTA (NCT04515017)
- Volunteers
- 50 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Keratoconus
Corneal Lenticule Implantation in Keratoconus Disease With Relex Smile Surgery
CORNEAL LENTICULE IMPLANTATION IN KERATOCONUS DISEASE WITH RELEX SMILE SURGERY
- Trial name
- NCT04591587
- Testing
- Lenticule Implantation in Keratoconus Disease with RELEX Smile Surgery
- Where
- Kosovo
- Volunteers
- 40 people
- Sponsor
- Dr. Faruk Semiz
Ocular Hypertension, Glaucoma
Safety and Efficacy of AGN 210669 Ophthalmic Solution in Patients With Ocular Hypertension or Primary Open-Angle Glaucoma
The study will evaluate the safety and efficacy of AGN-210669 ophthalmic solution in comparison with AGN-210669 vehicle and bimatoprost ophthalmic solution dosed once-daily each morning, in subjects with ocular hypertension or…
- Trial name
- NCT00809848
- Testing
- AGN-210669 ophthalmic solution, 0.075%, AGN-210669 ophthalmic solution, 0.05%, AGN-210669 ophthalmic solution, 0.025%
- Where
- United States
- Volunteers
- 172 people
- Sponsor
- Allergan
Myopia, Refractive Error
Effect of Contact Lens Wear on Immune Cell Density and Morphology of the Ocular Surface
The purpose of this study is to utilize in-vivo confocal microscopy to describe differences in corneal epithelial immune status across three lens care regimens in new contact lens wearers.
- Trial name
- NCT01250925
- Testing
- ReNu MultiPlus® MultiPurpose Solution, OPTI-FREE® RepleniSH®, Clear Care®
- Where
- 2 sites in United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
Macular Holes
Compare the Healing Process of Idiopathic Macular Hole With Different Surgical Techniques
To compare anatomic and functional results, and to evaluate postoperatively the healing process in 2 different techniques for the closure of the macular holes (MH)
- Trial name
- NCT03888625
- Testing
- Conventional ILM Peeling, Inverted ILM Peeling
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Federal University of São Paulo
Anterior Uveitis
Clinical Outcomes of Topical Ganciclovir Treatment in Cytomegalovirus Anterior Uveitis
The purpose of this study was to evaluate long term efficacy and safety of topical ganciclovir treatment in Cytomegalovirus (CMV) anterior uveitis.
- Trial name
- NCT01486693
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Diabetic Retinopathy, Diabetes Mellitus, Type 2
Longitudinal Observational Study of Diabetic Retinopathy Progression in Type 2 Diabetes Patients
The purpose of this clinical study is to explore structural and functional imaging and systemic biomarkers of diabetic retinopathy (DR) progression, in eyes from Type 2 Diabetes (T2D) patients with moderate to severe…
- Conditions
- Diabetic Retinopathy, Diabetes Mellitus, Type 2, Diabetic Complication, Retinal Disease
- Trial name
- IMPORTANT (NCT07458516)
- Where
- Portugal
- Volunteers
- 100 people
- Sponsor
- Association for Innovation and Biomedical Research on Light and Image
Retinal Vein Occlusion
Ranibizumab DosE Comparison and the Role of LAser in REtinal Vein Occlusions
The primary Objective of this study is to evaluate the safety and tolerability of intraocular injections of 0.5mg or 2.0mg of ranibizumab in patients with macular edema due to retinal vein occlusion.
- Trial name
- RELATE (NCT01003106)
- Testing
- Ranibizumab 0.5mg (monthly), Ranibizumab 2.0mg (monthly), Pro re nata (prn) ranibizumab
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Peter A Campochiaro, MD
Normal Tension Glaucoma
Effect of Netarsudil vs Brimonidine in NTG Patients on Latanoprost
A randomized, multicenter, investigator-masked prospective study of NTG patients currently on latanoprost 0.005% monotherapy, to study the effect of IOP change with the introduction of netarsudil 0.02% vs brimonidine 0.1%.
- Trial name
- NCT06449352
- Testing
- Netarsudil, Brimonidine
- Where
- 4 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Westlake Eye Specialists
Diabetic Retinopathy, Myopia
OCTA Metrics Repeatability and Reproducibility in Different Disorders
Retinal imaging is a corner stone in diagnosis of most retinal disorders. Standard imaging techniques e.g. fluorescein angiography and color fundus photography have a lot of limitations including limited resolution, invasive…
- Conditions
- Diabetic Retinopathy, Myopia, Choroidal Neovascularization, Healthy
- Trial name
- NCT04488887
- Testing
- Optical coherence tomography angiography
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Tanta University
Retinitis Pigmentosa, Maculopathy, Age Related
High Resolution, High-speed Multimodal Ophthalmic Imaging
Knowledge of the pathogenesis of ocular conditions, a leading cause of blindness, has benefited greatly from recent advances in ophthalmic imaging.
- Conditions
- Retinitis Pigmentosa, Maculopathy, Age Related, Macular Dystrophy, Macular Edema
- Trial name
- IMA-MODE (NCT04129021)
- Testing
- High-resolution retinal imaging through adaptive optics, High-resolution retinal imaging through holographic systems
- Where
- France
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts
Trachoma, Chlamydia Trachomatis
Impact of Two Alternative Dosing Strategies for Trachoma Control in Niger
Trachoma is a disease of poverty, which in the hyperendemic areas affects all individuals by the time they are two years old. Active disease is concentrated in children and occurs sporadically in adults.
- Trial name
- NCT00618449
- Testing
- Azithromcyin, Azithromycin
- Where
- 2 sites in United States, Niger
- Volunteers
- 1,139 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Blepharoptosis
Effect of Suture Material on Eyelid Height Stability After Anterior White-Line Advancement for Aponeurotic Ptosis.
What is the diagnosis and what treatment is indicated? The diagnosis is eyelid ptosis, which means drooping of the upper eyelid.
- Trial name
- WhiteLine_S (NCT07847749)
- Testing
- Anterior white-line advancement using an ABSORBABLE suture (POLYSORB 5-0). RED CODE., Anterior white-line advancement using a NON-ABSORBABLE suture (POLYPROPYLENE 5-0). BLUE CODE.
- Where
- Spain
- Volunteers
- 58 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Intraocular Lens, Cataract
Predicting Intraocular Lens Tilt Using OCT Measurements and Partial Least Squares Regression Modelling
During cataract surgery an artificial intraocular lens (IOL) is implanted in the eye to replace the lens and to correct the refraction for distance vision. Misalignment of IOLs can cause severe loss of visual quality.
- Trial name
- Tilt (NCT06305338)
- Testing
- Optical Coherence Tomography
- Where
- Austria
- Volunteers
- 110 people
- Sponsor
- Johannes Kepler University of Linz
Optic Glioma, Pediatric Brain Tumor, Optic Nerve Glioma
Modified CV Regimen in Optic Pathway Glioma
Optic pathway glioma (OPG) can result in visual deterioration. Symptomatic patients often report deficits in visual acuity (VA), visual field, visual-evoked potentials (VEPs), strabismus, proptosis, disc swelling, and other…
- Trial name
- NCT05278715
- Testing
- Carboplatin, Vincristine, Recombinant human endostatin
- Where
- China
- Volunteers
- 75 people
- Sponsor
- Beijing Sanbo Brain Hospital
Neovascular Glaucoma
Minimally Invasive Suprachoroidal Drainage for the Treatment of Neovascular Glaucoma
To explore the efficacy and safety of minimally invasive suprachoroidal drainage for the treatment of advanced neovascular glaucoma
- Trial name
- NCT07201415
- Testing
- minimally invasive suprachoroidal drainage
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Zhongnan Hospital
Hyperopia
PiXL for Correction of Hyperopia
This clinical study aims to investigate the efficacy and safety of PiXL in the refractive correction of low hyperopia.
- Trial name
- NCT03805425
- Testing
- PiXL
- Where
- Czechia
- Volunteers
- 25 people
- Sponsor
- Gemini Eye Clinic
Dry Eye Disease
Evaluation of P-321 Ophthalmic Solution Compared to Placebo in Subjects With Dry Eye Disease
The purpose of this study is to evaluate the effect of treatment with 0.017% P-321 on Dry Eye Symptoms.
- Trial name
- NCT02831387
- Testing
- P-321 Ophthalmic Solution
- Where
- 7 sites in United States
- Volunteers
- 47 people
- Sponsor
- Parion Sciences
Vision Disorders
SPOT Vision Screening
The purpose of this protocol is to determine if the Welch-Allyn Spot Vision Screener (SPOT) is effective at detecting various risk factors for poor vision in developmentally delayed children.
- Trial name
- NCT03479021
- Testing
- Welch-Allyn Spot Vision Screener
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Children's Hospital Colorado
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