Clinical trials: Eye Allergies
Myopia
Aberration-Free Refraction Correction
In the interest of improving visual quality after LASIK we have designed a multifaceted study to test the theoretical, physical, biomechanical and functional effects of commercial and independently designed aspherical ablation…
- Trial name
- NCT00172913
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Allergic Conjunctivitis
Safety Study of a Contact Lens With Ketotifen in Healthy, Normal Volunteers
The purpose of this study is to evaluate the safety of a novel contact lens in healthy normal volunteers
- Trial name
- NCT00569777
- Testing
- K-Lens (generic name not established) and Ketotifen
- Where
- 3 sites in United States
- Volunteers
- 310 people, healthy volunteers welcome
- Sponsor
- Vistakon Pharmaceuticals
Macula Hole
Macular Hole Surgery With Temporal Inverted Internal Limiting Membrane Flap (MARTIAL)
Since 1991, idiopathic macular holes (MH) can benefit from an effective treatment initially involving pars plana vitrectomy, stripping of epiretinal membranes and intraocular gas tamponade followed by facedown positioning.
- Trial name
- MARTIAL (NCT03287102)
- Testing
- Macular hole surgery
- Where
- France
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Cataract, Myopia
Evaluation of Visual Acuity in Myopic Cataract Patients Using Trifocal Intraocular Lens
The PanOptix trifocal IOL is a new trifocal intraocular lens which is proved to provide good range of vision for distance, intermediate and near and good visual quality in cataract patients with normal axial length.
- Conditions
- Cataract, Myopia, Intraocular Lens
- Trial name
- NCT04927117
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Aier School of Ophthalmology, Central South University
Excess Skin of Both Eyelids, Contrast Sensitivity
The Effect of Upper Blepharoplasty on Vision Quality in the Early Postoperative Period
Contrast sensitivity (CS) and tear film (TF) changes are noted in late postoperative period after upper blepharoplasty (UB), while the same was rarely investigated in the early postoperative period.
- Conditions
- Excess Skin of Both Eyelids, Contrast Sensitivity, Tear Film Insufficiency of Both Eyes, Corneal Topography
- Trial name
- NCT05549713
- Testing
- Upper blepharoplasty
- Where
- Croatia
- Volunteers
- 40 people
- Sponsor
- Osijek University Hospital
Dry Eye Disease
The Relationship of Residence Time and Visual Effect of Optive and Systane in Dry Eye Subjects
The benefits of artificial tears to relieve dry eye symptoms include, but are not limited to: stabilizing the tear film layer, fluid supplement action, improving visual acuity, and comfort.
- Trial name
- NCT00553579
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Southern California College of Optometry at Marshall B. Ketchum University
Allergic Conjunctivitis
AL-38583 Ophthalmic Solution for Allergic Conjunctivitis Associated Inflammation
The purpose of this study is to assess the safety and efficacy of AL-38583 in the treatment of the signs of inflammation associated with allergic conjunctivitis.
- Trial name
- NCT01001091
- Testing
- AL-38583 ophthalmic solution, AL-38583 ophthalmic solution vehicle, Dexamethasone ophthalmic suspension, 0.1%
- Volunteers
- 312 people
- Sponsor
- Alcon Research
Conjunctivitis, Allergic
Safety and Efficacy of Lastacaft® for the Prevention of Itching Associated With Allergic Conjunctivitis in Korea
This post-marketing surveillance study will assess the safety and efficacy of Lastacaft® Opthalmic Solution 0.25% (Alcaftadine) for the prevention of itching associated with Allergic Conjunctivitis as prescribed as standard of…
- Trial name
- NCT02555761
- Testing
- Alcaftadine Ophthalmic Solution 0.25%
- Where
- 81 sites in South Korea
- Volunteers
- 3,423 people
- Sponsor
- Allergan
Allergic Conjunctivitis
A Single-Center Evaluation of the Anti-Inflammatory Effects of Lastacaft as Measured by In-Vivo Confocal Microscopy
A Single-Center Evaluation of the Anti-Inflammatory Effects of Lastacaft ® as Measured by In-Vivo Confocal Microscopy
- Trial name
- NCT02308501
- Testing
- Lastacaft ®
- Volunteers
- 25 people
- Sponsor
- ORA, Inc.
Amyotrophic Lateral Sclerosis (ALS), Angina, Stable
Quest to Analyze One Thousand Humans Meditating
This study will be focused on assessing the molecular, physiological, and emotional correlates of an intensive meditation experience in the context of a retreat setting in a large 2000 plus-person cohort comprised of healthy and…
- Conditions
- Amyotrophic Lateral Sclerosis (ALS), Angina, Stable, Anxiety, Asthma
- Trial name
- QUANTUM (NCT06583395)
- Testing
- Advanced multi-component meditation practice
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Tobias Moeller-Bertram
Allergic Rhinitis
Effect of Veramyst on the Nasal and Ocular Symptoms of the Early Reaction to Nasal Challenge With Allergen
The purpose of this study is to help us to a better understanding of how nose and eye symptoms are related in patients with allergies.
- Trial name
- NCT00791973
- Testing
- fluticasone furoate
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Allergic Conjunctivitis
Sea Water in Allergic Conjunctivitis
Background and purpose: Allergic conjunctivitis has increased alarmingly in recent years. The objectives of the study are: 1) To establish the safety and efficacy of applying eyewashes in spray form as monotherapy on the symptoms…
- Trial name
- NCT04695795
- Volunteers
- 50 people
- Sponsor
- University of Valencia
Allergic Conjunctivitis
Study of Olopatadine HCl Ophthalmic Solutions Compared to Vehicle Using the Conjunctival Allergen Challenge (CAC) Model of Acute Allergic Conjunctivitis in Japanese Subjects
The purpose of the study is to demonstrate safety and efficacy of Olopatadine 0.2% compared to its vehicle in Japanese subjects in the treatment of acute allergen-mediated conjunctivitis using the conjunctival allergen challenge…
- Trial name
- NCT00987272
- Testing
- Olopatadine Hydrochloride Ophthalmic Solution, 0.2%, Olopatadine Hydrochloride Ophthalmic Solution, 0.1%, Olopatadine 0.2% Vehicle
- Volunteers
- 267 people
- Sponsor
- Alcon Research
Stevens-Johnson Syndrome, Toxic Epidermal Necrolysis (Lyell) Syndrome
Topical Infliximab in Autoimmune Eyes With Keratoprosthesis
The Boston Keratoprosthesis type I (KPro) is a prosthetic cornea used to treat several causes of corneal blindness. Some categories of patients, including those with auto-immune diseases such as Stevens-Johnson syndrome, toxic…
- Conditions
- Stevens-Johnson Syndrome, Toxic Epidermal Necrolysis (Lyell) Syndrome, Mucous Membrane Pemphigoid
- Trial name
- NCT02126020
- Testing
- topical infliximab
- Where
- 2 sites in United States, Canada
- Sponsor
- James Chodosh, MD, MPH
Cataract After, Astigmatism
Influence of Residual Astigmatism on Visual Acuity in Patients Undergoing Cataract Surgery With Trifocal Intraocular Lens Implantation
MAIN OBJECTIVE: To assess the influence of residual astigmatism on visual acuity in the different lens foci in patients operated on for cataracts with a trifocal intraocular lens implant.
- Conditions
- Cataract After, Astigmatism, IOL, Visual Acuity
- Trial name
- NCT04387721
- Testing
- Kind of trifocal IOL
- Where
- Spain
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Enrique Ordiñaga-Monreal, OD, MSc
Amblyopia
Combining Donepezil With Perceptual Learning in Normal and Amblyopic Human The Effect of Donepezil on Perceptual Learning in Adult Amblyopia
The research deals with amblyopia or lazy eye, a condition that affects about 3% of the population, and results in a variety of visual deficits.
- Trial name
- NCT03109314
- Testing
- Donepezil, Single-letter training, Uncrowd training
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Dennis Levi
Low Vision
Performance of Rigid Gas Permeable (RGP) Scleral Contact Lenses With a Passive Artificial Iris
Data from 15 healthy subjects will be recorded in two testing sessions spread on two days, using three lens designs (A, B and C).
- Trial name
- RGPIRIS_PA (NCT04040790)
- Testing
- Scleral contact lens without a passive artificial iris, Scleral contact lens with a passive artificial iris with low contrast (<1:5), Scleral contact lens with a passive artificial iris with high contrast (>1:5)
- Where
- Belgium
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Ghent
Allergic Conjunctivitis of Both Eyes
Daydrop® Triple Action for Allergic Eye Symptoms
The study is designed to evaluate the safety and efficacy of Daydrop® Triple Action for the symptomatic treatment of seasonal or perennial allergic conjunctivitis.
- Trial name
- NCT07805759
- Testing
- Eye Drops, Lubricant
- Where
- Spain
- Volunteers
- 49 people
- Sponsor
- i+Med S.Coop.
Cataract
Aqualase Versus Torsional ip. A Study on Endothelial Cells, Corneal Edema and Corneal Sensitivity
Objective of this study is the comparative assessment of the impact of torsional and liquefaction technologies on endothelial cells (ECC), corneal edema (CCT) and corneal sensitivity (CCS) in a sample of cataract patients.
- Trial name
- NCT01480557
- Testing
- liquefaction, Torsional ip
- Where
- Greece
- Volunteers
- 75 people
- Sponsor
- Democritus University of Thrace
Allergic Conjunctivitis
Effectiveness of PR013 Topical Ophthalmic Drops Compared to Vehicle for the Treatment of Allergic Conjunctivitis
To evaluate the efficacy and safety of PR013 topical ophthalmic drops (0.045% and 0.06%) compared to vehicle for the treatment of the signs and symptoms of allergic conjunctivitis using a modified Conjunctival Allergen Challenge…
- Trial name
- NCT03368339
- Testing
- PR013 (0.045%), PR013 (0.06%), Vehicle
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Realm Therapeutics, Inc.