Clinical trials: Eye Manifestations
Overactive Bladder
Specified Drug Use-results Survey of Betanis Tablets
To investigate the effects of mirabegron on the symptoms of glaucoma in overactive bladder (OAB) patients with coexisting glaucoma.
- Trial name
- NCT01898624
- Testing
- mirabegron
- Where
- 7 sites in Japan
- Volunteers
- 300 people
- Sponsor
- Astellas Pharma Inc
Vision Impairment
Providing Access to the Visual Environment
Providing Access to the Visual Environment is a pediatric low vision grant which has the ability to provide comprehensive, interdisciplinary low vision rehabilitation services to every child in Tennessee with a vision impairment.
- Trial name
- NCT00341744
- Where
- United States
- Volunteers
- 795 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Visual Snow Syndrome, Migraine
Investigating Brain Function in People With and Without Visual Snow Syndrome Using Adaptation to Visual Stimuli
The goal of this study is to learn more about the brain pathways and activity involved in creating Visual Snow Syndrome (VSS). The main questions it aims to answer are: Does VSS arise from spontaneous activity in brain pathways?…
- Conditions
- Visual Snow Syndrome, Migraine, Healthy
- Trial name
- VPVSS (NCT06961864)
- Testing
- Visual Adaptation, Assessments and Questionnaires, Functional Magnetic Resonance Imaging (fMRI)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Amblyopia, Anisometropia
A Randomized Controlled Trial of Gabor-Based Perceptual Learning for Adult Amblyopia
This study is initiated and conducted by the Shanghai Eye Disease Prevention and Treatment Center / Shanghai Eye Hospital. Many people once believed that amblyopia (commonly known as "lazy eye") could only be treated during…
- Trial name
- NCT07764198
- Testing
- Gabor training
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Jiannan Huang
Anesthesia and Analgesia, Anesthesia, Endotracheal
Opioid Free Versus Opioid Balanced Anesthesia in Ophthalmic Surgery
Anesthesia without the use of opioid (Opioid free anesthesia) is an alternative to conventional opioid balanced anesthesia, with less post operative nausea and vomiting, and comparable analgesia.
- Trial name
- NCT06382831
- Testing
- Dexmedetomidine, Fentanyl
- Volunteers
- 104 people
- Sponsor
- Universitas Indonesia
Binocular Vision Disorder, Visual Impairment
Evaluation of Tests Performance on a New Digital Orthoptic Platform
This clinical trials aims to evaluate Tests Performance on a New Digital Orthoptic Platform.
- Trial name
- ESPPADON (NCT02651389)
- Where
- France
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Amblyopia, Anisometropic, Amblyopia Strabismic
Validation of New Virtual Reality Treatment for Children With Lazy Eye Using the Vedea Amblyopia Therapy (VAT)
The purpose of this clinical study is to validate the effectiveness of the Vedea Amblyopia Therapy (VAT) as a treatment for children with lazy eye.
- Conditions
- Amblyopia, Anisometropic, Amblyopia Strabismic, Amblyopia
- Trial name
- VAT (NCT05620173)
- Testing
- Vedea Amblyopia Therapy (VAT), Occlusion therapy
- Where
- 2 sites in Netherlands
- Volunteers
- 74 people
- Sponsor
- Vedea Healthware BV
Idiopathic Intracranial Hypertension
Surgical Idiopathic Intracranial Hypertension Treatment Trial
Randomized trial of adults (≥18 years old) with idiopathic intracranial hypertension and moderate to severe visual loss without substantial recent treatment who are randomly assigned to (1) medical therapy, (2) medical therapy…
- Trial name
- SIGHT (NCT03501966)
- Testing
- Acetazolamide, Optic Nerve Sheath Fenestration, Ventriculoperitoneal CSF Shunting
- Where
- 36 sites in United States, Canada and 1 more
- Volunteers
- 7 people
- Sponsor
- Jaeb Center for Health Research
Stroke, Ischemic, Quadrantanopia
Visual Rehabilitation After Occipital Stroke
This research aims to examine changes in plastic potential of the visual system with time from stroke affecting primary visual cortex.
- Conditions
- Stroke, Ischemic, Quadrantanopia, Vision Loss Partial, Visual Field Defect, Peripheral
- Trial name
- NCT04798924
- Testing
- Subacute Training in the intact field, Subacute Training in the blind field, Chronic Training in the blind field
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Rochester
Language Development Disorders
Memorisation of Phonologic Information Among Children With Oral Language Developement Disorder
The disorder of oral language development is defined by the delay in language acquisition in children who possess efficient auditory acuity and normal non verbal intellect.
- Trial name
- MEMENTO (NCT02609542)
- Testing
- Eye Tracking
- Where
- France
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Lille Catholic University
Cataracts, Alzheimer's Disease
Cataract Removal and Alzheimer's Disease
Two very common aging-related diseases in older adults are Alzheimer's disease (AD) and cataracts. In elderly adults, these two diseases frequently occur in the same person.
- Trial name
- NCT00921297
- Testing
- Immediate Cataract Surgery
- Where
- 2 sites in United States
- Volunteers
- 122 people
- Sponsor
- University Hospitals Cleveland Medical Center
Postoperative Pain, Cataract
Midazolam Additive to Local Anesthetic in Peribulbar Block
Regional eye blocks are usually preferred for ophthalmic procedures. Peribulbar block (PBB) is a safe alternative for patients undergoing cataract surgery.
- Conditions
- Postoperative Pain, Cataract, Local Anaesthetic Complication, Midazolam
- Trial name
- NCT03397069
- Testing
- Peribulbar block (control), Peribulbar block(M1), Peribulbar block(M2)
- Where
- Saudi Arabia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Al Jedaani Hospital
Parkinson Disease, Parkinsonism
Misfolded Proteins in the Skin of People With Parkinson's Disease and Other Parkinsonism
The purpose of this study is to determine whether identification of misfolded proteins in the skin will help to determine what sort of parkinsonism someone has.
- Conditions
- Parkinson Disease, Parkinsonism, Dementia With Lewy Bodies, Multiple System Atrophy
- Trial name
- NCT04518059
- Testing
- punch skin biopsy
- Where
- 2 sites in United States
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Postoperative Pain
Postoperative Pain in Orbital Disease and Ocular Tumor
The purpose of this study is to evaluate the postoperative pain after general anesthesia of orbital diseases and ocular tumor patients.
- Trial name
- NCT02704715
- Testing
- general anesthesia,orbital operation
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Sun Yat-sen University
Amblyopia
Augmenting Patching Treatment for Amblyopia With Physical Exercise
Researches are trying to establish whether moderate exercise enhances the treatment benefit of patching 2 hours a day for residual amblyopia in children.
- Trial name
- NCT03822806
- Testing
- Physical Exercise in addition to Patching
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Mayo Clinic
Spinal Cord Injury Cervical, Tetraplegia
Epidural Stimulation for Upper Extremity Function
Restoring upper extremity function in patients with cervical spinal cord injury is extremely important for patients' independence and quality of life.
- Trial name
- NCT06437548
- Testing
- Percutaneous spinal cord stimulation
- Volunteers
- 20 people
- Sponsor
- Brigham and Women's Hospital
Progressive Supranuclear Palsy (PSP), Healthy Participants
First-in-Human Study for the Safety and Evaluation of Two 4R Tau Ligands as Potential PET Radioligands for Imaging Tau Protein in the Brain
This clinical study is being conducted to learn more about two new imaging drugs, called [18F]ABBV-964i and [18F]ABBV-965i, which are designed to help doctors see changes in the brain related to a condition called Progressive…
- Trial name
- NCT07348276
- Testing
- [18F]ABBV-964i, [18F]ABBV-965i, Lead Candidate
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Invicro
Migraine Disorders, Photophobia
How Can we Treat Photophobia in Migraine
Photophobia, the aberrantly increased sensitivity to light, is a common symptom in migraine patients and light discomfort is frequently found as a trigger for migraine attacks.
- Trial name
- NCT05369910
- Testing
- Light exposure (Flash), Light deprivation (Dark)
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Age Related Macular Degeneration
Second Line Therapy to Treat Age-related Macular Degeneration (AMD) for Patients Not Responding Well to Lucentis Therapy by Itself
The purpose of this study is to demonstrate that Visudyne-Lucentis-dexamethasone (V-L-D) triple therapy will give similar efficacy and safety results as Lucentis monotherapy.
- Trial name
- NCT00457678
- Testing
- Visudyne, Lucentis, Dexamethasone
- Sponsor
- Vitreous -Retina- Macula Consultants of New York
Brain and Central Nervous System Tumors, Chordoma
Polyvinylpyrrolidone-Sodium Hyaluronate Gel in Reducing Pain From Oral Mucositis in Young Patients With Cancer
RATIONALE: Polyvinylpyrrolidone-sodium hyaluronate gel may lessen the pain of oral mucositis, or mouth sores, in patients undergoing treatment for cancer.
- Conditions
- Brain and Central Nervous System Tumors, Chordoma, Kidney Cancer, Leukemia
- Trial name
- NCT00349024
- Testing
- polyvinylpyrrolidone-sodium hyaluronate gel
- Where
- 21 sites in Ireland, United Kingdom
- Volunteers
- 50 people
- Sponsor
- Children's Cancer and Leukaemia Group
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