Clinical trials: Eye Movement Disorder
Convergence Insufficiency
Screening for Convergence Insufficiency in School-age Children
The purpose of this study was to assess the ability of common tests of eye alignment, convergence, and accommodation to identify children with convergence insufficiency in a school screening setting.
- Trial name
- NCT00472407
- Where
- United States
- Volunteers
- 282 people, healthy volunteers welcome
- Sponsor
- Ohio State University
ADHD, Convergence Insufficiency
Study of Eyes and Attention Deficit (SEAD)
Attention-Deficit Hyperactivity Disorder (ADHD) is considered to be one of the most prevalent chronic health conditions in children. It affects between 4% and 12% of young children.
- Conditions
- ADHD, Convergence Insufficiency, Accommodative Insufficiency
- Trial name
- NCT00472511
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ohio State University
TBI (Traumatic Brain Injury), Ocular Motility Disorders
Frontoparietal Priority Maps as Biomarkers for MTBI
The purpose of this study is to determine whether there is a quantitative relationship between brain processes seen by a MRI and visual deficits caused by mild to moderate traumatic brain injuries (mTBI).
- Trial name
- NCT02251002
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Amblyopia, Strabismus
Amblyopia and Strabismus Detection Using a Pediatric Vision Scanner
The purpose of this project is to compare the performance of the Pediatric Vision Scanner (PVS) with the Gold Standard Examination to determine the effectiveness of the PVS at detecting amblyopia and strabismus.
- Trial name
- NCT01726842
- Testing
- Pediatric Vision Scanner
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Rebiscan, Inc.
Strabismus, Exotropia
A Novel Diagnostic Method for Exotropia Using Video-oculography
Thirty-four subjects with constant exotropia were included. Two independent ophthalmologists measured the angle of ocular deviation using alternate prism cover test (APCT).
- Trial name
- NCT03119311
- Testing
- Video-oculography, APCT
- Where
- South Korea
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Inje University
Alzheimer Disease, Early Onset
Epileptiform Activity During REM Sleep in Alzheimer's Disease
Recent clinical data showed that patients with Alzheimer Disease (AD) might present epilepsy at early stages of the disease (Cretin et al., 2016, Vossel et al., 2016).
- Trial name
- EREMAD (NCT03923569)
- Testing
- Overnight polysomnography, blood sample, high-resolution MRI scan
- Where
- France
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Glaucoma, Retinal Disease
The EASE Study - Human Factor and Usability Testing of a Binocular OCT System
Ophthalmology is among the most technology driven of all medical specialties, with advanced medical imaging devices - and specialised computer software - increasingly adopted for routine clinical use.
- Conditions
- Glaucoma, Retinal Disease, Strabismus, Healthy Volunteers
- Trial name
- EASE (NCT02822612)
- Testing
- Binocular OCT prototype
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University College, London
Emergence Delirium, Strabismus
The Occurrence of Emergence Agitation in Pediatric Strabismus Surgery
The present trial conducted to demonstrate the administration of sugammadex as reversal of neuromuscular blockade agent reduces the incidence of emergence agitation (EA) comparing to neostigmine
- Conditions
- Emergence Delirium, Strabismus, Pediatric ALL
- Trial name
- NCT06035757
- Testing
- Bridion 200 MG in 2 ML Injection, Pyridostigmine Bromide 5 MG/ML
- Where
- South Korea
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Konkuk University Medical Center
Mitochondrial Disorders, Mitochondrial Genetic Disorders
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)
The North American Mitochondrial Disease Consortium (NAMDC) maintains a patient contact registry and tissue biorepository for patients with mitochondrial disorders.
- Conditions
- Mitochondrial Disorders, Mitochondrial Genetic Disorders, Mitochondrial Diseases, Disorder of Mitochondrial Respiratory Chain Complexes
- Trial name
- NAMDC (NCT01694940)
- Where
- 17 sites in United States, Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Columbia University
PTSD
Clinical Assessment of the Flash - Eye Movement Desensitization and Reprocessing
To assess the Flash version of EMDR in reductions of the disturbance of upsetting memories at post-intervention, and 1-month follow up within a double-blinded, online 2-arm randomized controlled trial (RCT) with self-report…
- Trial name
- Flash-EMDR (NCT05262127)
- Testing
- Flash Version of EMDR
- Where
- 2 sites in Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- York University
Progressive Supranuclear Palsy
Quality of Life of the Patient and the Burden of the Caregiver in Progressive Supranuclear Palsy
Progressive supranuclear palsy (PSP) is a rare neurodegenerative disease from the parkinsonian syndrome group. PSP is characterised by the association of a non-doparesponsive parkinsonian syndrome with axial signs.
- Trial name
- Qual-PSP (NCT03638505)
- Testing
- PSP-QoL
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Assistance Publique Hopitaux De Marseille
Healthy, Strabismus
Development of the Eye Motor System During the First 7 Months of Life in Infants With and Without a Family History of Cross-Eye
Little is known about the development of the ocular, or eye, motor system (the parts of the brain that control how the eyes move) in children.
- Trial name
- NCT00001143
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Reflex, Abnormal, Bilateral Vestibulopathy
Covert Saccade Triggers in Bilateral Vestibular Hypofunction
Patients with chronic bilateral vestibular hypofunction may suffer from a visual instability during head movement called oscillopsia.
- Conditions
- Reflex, Abnormal, Bilateral Vestibulopathy, Healthy Volunteers
- Trial name
- CS-TRIGGER (NCT04268615)
- Testing
- Covert Saccades and Virtual Reality, Actives versus passives Head Impulses, Visually guided saccades
- Where
- France
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Alzheimer's Disease (AD), Progressive Supranuclear Palsy (PSP)
Evaluation of [18F]MNI-815 as a Potential PET Radioligand for Imaging Tau Protein in the Brain of Patients With Tauopathies
The overall goal of this imaging trial is to characterize [18F]MNI-815, a PET radioligand for imaging Tau.
- Conditions
- Alzheimer's Disease (AD), Progressive Supranuclear Palsy (PSP), Cortical Basal Syndrome (CBS), Frontal Temporal Dementia (FTD)
- Trial name
- NCT02531360
- Testing
- [18F]MNI-815 (MNI-815)
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Molecular NeuroImaging
Parkinson Disease
Quantification of Parkinson's Disease Patients as a Biomarker for Classification, Prediction and Response to Treatment
This is a three-armed open investigational study that aims to differentiate, quantify, and categorize abnormal eye movements and upper limbs movements in patients with Parkinson's disease.
- Trial name
- NCT06586320
- Testing
- 150% of their routine home dopaminergic medications dose right in the clinic, Evaluation of mathematical models
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Stardots AB
Parkinson's Disease (PD), Parkinsonism
Identifying Biomarkers of Parkinson's Disease Using Magnetic Resonance Imaging (MRI)
This study is designed to determine if magnetic resonance imaging (MRI) measures can be used to diagnose and monitor the progression of Parkinson's disease (PD) while distinguishing between PD and parkinsonisms [conditions that…
- Conditions
- Parkinson's Disease (PD), Parkinsonism, Progressive Supranuclear Palsy (PSP), Multiple System Atrophy (MSA)
- Trial name
- NCT01888185
- Where
- United States
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Corticobasal Degeneration (CBD), Corticobasal Syndrome (CBS)
4-Repeat Tauopathy Neuroimaging Initiative - Cycle 2
The goal of this study is to identify the most reliable methods of analysis for tracking CBD, PSP, and o/vPSP over time. The results from this study may be used in the future to calculate statistical power for clinical drug…
- Conditions
- Corticobasal Degeneration (CBD), Corticobasal Syndrome (CBS), Cortical-basal Ganglionic Degeneration (CBGD), Progressive Supranuclear Palsy (PSP)
- Trial name
- 4RTNI-2 (NCT02966145)
- Testing
- Observational Study
- Where
- 8 sites in United States, Canada
- Volunteers
- 293 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Cycloplegia, Refractive Errors
Cycloplegic Refraction in Pediatric Patients With Esotropia
The primary outcome of this study is to compare cyclopentolate 1% and tropicamide 1% for cycloplegic refractions in pediatric populations with esotropia.
- Conditions
- Cycloplegia, Refractive Errors, Esotropia, Vision Disorders
- Trial name
- NCT06077682
- Testing
- Cyclopentolate, Tropicamide
- Where
- 2 sites in Jordan, Qatar
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Islamic Hospital, Jordan
Primary Parkinsonism, Secondary Vascular Parkinson Disease
Application of Machine Learning Method in Validation of Screening Cognitive Test for Parkinsonisms
Based on a prospectively collected data analysis, a new tool, namely CoMDA (Cognition in Movement Disorders Assessment) is developed by merging each item of Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment…
- Conditions
- Primary Parkinsonism, Secondary Vascular Parkinson Disease, Multiple System Atrophy, Supranuclear Palsy, Progressive
- Trial name
- CoMDA-ML-P (NCT04858893)
- Testing
- CoMDA associated with Neural Net 91 classificator
- Where
- Italy
- Volunteers
- 562 people, healthy volunteers welcome
- Sponsor
- Ospedale Generale Di Zona Moriggia-Pelascini
Amblyopia, Strabismus
Screening for 3-D Visual Disorders in Preschool Children
Visual screening is necessary among pre-school children as they found themselves in a critical period of visual developement. To date, there are no national vision screening program that has been implemented nationwide.
- Conditions
- Amblyopia, Strabismus, Anisometropia
- Trial name
- VISION (NCT05204069)
- Testing
- Instillation of cyclopentolate
- Where
- France
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris