Clinical trials: Eye--Refractive Errors
Refractive Errors
Air Optix Plus HydraGlyde Multifocal Daily/Extended Wear Contact Lenses
The purpose of this Post-Market Clinical Follow-Up (PMCF) study is to assess long term performance and safety of Air Optix plus HydraGlyde Multifocal soft contact lenses in a real-world setting when worn as daily wear or extended…
- Trial name
- NCT05886894
- Testing
- Lotrafilcon B multifocal soft contact lenses, Comfilcon A multifocal soft contact lenses
- Where
- 8 sites in United States
- Volunteers
- 351 people
- Sponsor
- Alcon Research
Presbyopia
An Evaluation of the Efficacy and Safety of CSF-1 in the Temporary Correction of Presbyopia (NEAR-2)
This is a 4-visit, multi-center, randomized, double-masked, vehicle-controlled study evaluating the safety and efficacy of CSF-1 in the temporary correction of presbyopia.
- Trial name
- NEAR-2 (NCT04599972)
- Testing
- CSF-1, Vehicle
- Where
- 18 sites in United States
- Volunteers
- 304 people
- Sponsor
- Orasis Pharmaceuticals Ltd.
Myopia
Clinical Evaluation of a Myopia Control Lens in Slowing Myopia Progression.
This is a mono-centre, prospective, one-arm, unmask clinical trial to evaluate the effectiveness of test lens in slowing myopia progression with respect to axial length elongation compared to a single vision spectacle lens from…
- Trial name
- NCT05534022
- Testing
- Test myopia control lenses (BSL)
- Where
- Singapore
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Essilor International
Hyperopia and Myopia
Eye Imaging for the Study of Childhood Myopia
Myopia (nearsightedness) is increasing worldwide and is becoming a serious public health problem. Studies estimate that by 2050, if no action is taken, almost half of the world's population will be myopic.
- Trial name
- SELENA (NCT07335146)
- Testing
- Ophtalmic measurements to estimate geometrical distances, MRI, Ophtalmic measurements to measure wavefront aberrations
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Essilor International
Myopia
Sustained Effect of Red-light Therapy for Myopia Control: A 2-Year Post-Trial Follow-up Study
To evaluate the long-term efficacy and safety of red-light therapy for myopia control over 2 years, and the potential rebound effect after treatment cessation.
- Trial name
- NCT06232161
- Testing
- Red-light therapy device, Spectacles
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Beijing Airdoc Technology Co., Ltd.
Presbyopia
LaserACE® Procedure Restore Visual Function and Range of Accommodation LaserACE® Procedure
A new minimally invasive procedure for treating presbyopia is being evaluated to determine if there is improvement in near and intermediate vision after treatment.
- Trial name
- NCT01491360
- Testing
- LaserACE(R)
- Where
- Taiwan
- Volunteers
- 8 people
- Sponsor
- ACE Vision Group, Inc.
Myopia
Clinical Evaluation of Two Daily Disposable Silicone Hydrogel Contact Lenses
The purpose of this crossover study was to evaluate the end-of-day comfort of two commercially available, daily disposable, silicone hydrogel contact lenses.
- Trial name
- NCT01561560
- Testing
- Delefilcon A contact lenses, Narafilcon A contact lenses
- Where
- United States
- Volunteers
- 123 people
- Sponsor
- Alcon Research
Myopia
WaveLight® EX500 Excimer Laser System for the Correction of Myopia Using InnovEyes™ in Conjunction With InnovEyes™ Sightmap
The purpose of this study is to evaluate the safety and effectiveness of the WaveLight EX500 excimer laser system for the correction of myopia with and without astigmatism using InnovEyes in conjunction with InnovEyes sightmap.
- Trial name
- NCT04219891
- Testing
- WaveLight EX500 excimer laser system with InnovEyes sightmap, LASIK, InnovEyes sightmap
- Where
- 9 sites in United States
- Volunteers
- 272 people
- Sponsor
- Alcon Research
Myopia
Safety and Efficacy of T10430 Eye Drops in Controlling Paediatric Myopia Progression
Axial myopia is a type of nearsightedness that happens when the eye is too long from front to back. This causes distant vision to be blurry.
- Trial name
- NCT07522242
- Testing
- T10430 lower dose, T10430 middle dose, T10430 higher dose
- Where
- 10 sites in Jordan, South Africa and 1 more
- Volunteers
- 200 people
- Sponsor
- Laboratoires Thea
Refractive Errors
Clinical Performance of Two Daily Disposable Contact Lenses - Study 1
The purpose of this study is to evaluate end of day (EOD) visual acuity (VA) at distance when wearing Precision1™ contact lenses compared to Acuvue® Moist contact lenses.
- Trial name
- NCT03969290
- Testing
- Verofilcon A contact lenses, Etafilcon A contact lenses
- Where
- Germany
- Volunteers
- 69 people
- Sponsor
- Alcon Research
Myopia
Two Week Cross-Over Study Comparing Two Daily Disposable Contact Lenses
This study seeks to evaluate and compare the clinical performance of two daily disposable soft contact lenses, Proclear 1 Day and 1-Day Acuvue Moist.
- Trial name
- NCT01155323
- Testing
- etafilcon A, omafilcon A
- Where
- Singapore
- Volunteers
- 118 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Astigmatism
Evaluation Study on Corneal Lens for Vision Correction
The objective of this study is to evaluate the fitting and visual outcomes of Nexis Lens, made of silicone commonly used in the contact lens industry, on healthy eye with or without astigmatism.
- Trial name
- NCT02053688
- Testing
- Astigmatic Correction Lens (Nexis ACCL lenses), Toric Soft Contact Lenses
- Where
- 6 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- FORSIGHT Vision3
Astigmatism
Orientation Characteristics of Daily Disposable Toric Contact Lenses
Brief summary: Approximately 30 soft toric contact lens adapted subjects will be enrolled in this feasibility, bilateral, randomized, double-masked (subject and investigator), repeated measures insertion study.
- Trial name
- NCT06069609
- Testing
- kalifilcon A Daily Disposable Toric, Acuvue Oasys 1-Day for Astigmatism
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Ametropia, Myopia
Post-market Clinical Follow-up Study of Alcon TOTAL30® Contact Lenses (Lehfilcon A)
The purpose of this Post-Market Clinical Follow-Up (PMCF) study is to continuously assess the visual performance and safety of TOTAL30 Sphere and TOTAL30 for Astigmatism contact lenses in a real-world setting across a broad…
- Conditions
- Ametropia, Myopia, Hyperopia, Astigmatism
- Trial name
- NCT06408649
- Testing
- Lehfilcon A spherical contact lenses, Lehfilcon A toric contact lenses
- Where
- United States
- Volunteers
- 129 people
- Sponsor
- Alcon Research
Astigmatism, Myopia
Effect of a Myopia Control Lens on the Astigmatism in Children
The goal of this clinical trial is to investigate over a one-year period the effect of myopia control spectacle lenses on astigmatism in children aged 6 to 13 years with myopia and astigmatism.
- Trial name
- MAC (NCT07810725)
- Testing
- Lenslet-based myopia control spectacle lens
- Volunteers
- 15 people
- Sponsor
- Essilor International
Refractive Error
Lens Wearing Experience and Biocompatibility of a Marketed Multi-Purpose Disinfecting Solution in Silicone Hydrogel and Soft Contact Lens Wearers
The purpose of this study was to describe mean differences in corneal staining (type and area) for OPTI-FREE PureMoist Multi-Purpose Disinfecting Solution (MPDS) at Day 30 compared to Baseline (Day 0).
- Trial name
- NCT01484938
- Testing
- OPTI-FREE PureMoist
- Where
- United States
- Volunteers
- 175 people
- Sponsor
- Alcon Research
Myopia, Amblyopia
Real Word Study on Myopia Control With Repeated Red Light Therapy for Ages of 3~6 Years Old
Repeated Red Light Therapy had been used as an amblyopia therapy for children as well as the myopia control in primary schools. However, ultra low lever of red light therapy with irradiance of 0.37mW and 0.60mW effectiveness and…
- Trial name
- RMC (NCT05811598)
- Testing
- repeated ultra low lever red light
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Beijing Airdoc Technology Co., Ltd.
Myopia
A Comparison of Manufacturing Processes for AIR OPTIX® COLORS Contact Lens
The purpose of this feasibility study was to compare AIR OPTIX® COLORS contact lenses manufactured using an automated process to AIR OPTIX® COLORS contact lenses manufactured using a semi-automatic process.
- Trial name
- NCT01614678
- Testing
- Lotrafilcon B contact lens with color, automated, Lotrafilcon B contact lens with color, semi-automated
- Volunteers
- 49 people
- Sponsor
- CIBA VISION
Myopia
A Contralateral Dispensing Clinical Trial of Study Test Sapphire Lens Against Enfilcon A Silicone Hydrogel Lens
This was be a randomized, contralateral, double-masked, dispensing study comparing the Study test lens against the control lens over one month of lens wear. The study results were not used for design validation of test lens.
- Trial name
- NCT02518490
- Testing
- Sapphire Lens, enfilcon A
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- CooperVision, Inc.
Presbyopia
Clinical Evaluation of Two New Silicone Hydrogel Multifocal Products
The objective of this trial is compare the visual performance, ratings, and preference of two multifocal, soft contact lenses.
- Trial name
- NCT00909792
- Testing
- Lotrafilcon B, Senofilcon A
- Volunteers
- 259 people
- Sponsor
- CIBA VISION