Clinical trials: Eye--Refractive Errors
Aphakia, Presbyopia
Post Market Clinical Evaluation of Clareon PanOptix Pro and Clareon PanOptix Pro Toric IOLs
The purpose of this study is to collect safety and performance data on two approved intraocular lenses (IOLs). This study will be conducted in participants who require cataract surgery in both eyes.
- Trial name
- NCT07161635
- Testing
- Clareon PanOptix Pro/Pro Toric Trifocal IOL, Phacoemulsification
- Where
- 5 sites in United States
- Volunteers
- 110 people
- Sponsor
- Alcon Research
Refractive Errors
Clinical Characterization of an Investigational Frequent Replacement Daily Wear Silicone Hydrogel Sphere Contact Lens
The primary objective of this study is to evaluate the overall clinical performance of an investigational silicone hydrogel contact lens over 7 days of daily wear.
- Trial name
- NCT04702984
- Testing
- LID021201 contact lenses, OPTI-FREE multipurpose solution
- Where
- 3 sites in United States
- Volunteers
- 39 people
- Sponsor
- Alcon Research
Presbyopia
Comparison of a Multifocal Contact Lens to a Traditional Multifocal Contact Lens
The purpose of the trial is to compare the performance of two multifocal contact lens systems/products in established presbyopic subjects.
- Trial name
- NCT00886119
- Testing
- Lotrafilcon B multifocal contact lens, Omafilcon A multifocal contact lens
- Volunteers
- 48 people
- Sponsor
- CIBA VISION
Refractive Error
Performance and Acceptability of iDesign
The results of this trial will demonstrate that the iDesign System performs as intended and is acceptable in a clinical setting.
- Trial name
- NCT01220466
- Testing
- STAR S4IR LASIK with iDesign Aberrometer
- Where
- 4 sites in Canada
- Volunteers
- 77 people
- Sponsor
- Abbott Medical Optics
Astigmatism
Comparison of Senofilcon A Toric Lenses to Balafilcon A Toric Lenses Over Extended Wear Period
To evaluate two toric contact lenses on the ocular physiology of existing contact lens wearers when used in an extended wear modality of days/six nights.
- Trial name
- NCT00762502
- Testing
- senofilcon A toric contact lens, balafilcon A toric contact lens
- Where
- 8 sites in United States, Australia
- Volunteers
- 112 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
Evaluation of Daytime Corneal Swelling During Wear of Galyfilcon A Lenses
The purpose of this study is to evaluate corneal swelling, limbal redness, and endothelial bleb response to wearing galyfilcon A lenses in asian eyes.
- Trial name
- NCT01482819
- Testing
- galyfilcon A, galyfilcon A plus, lotrafilcon A
- Where
- Australia
- Volunteers
- 21 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Refractive Error
Evaluation of a Johnson & Johnson Vision Care Investigational Contact Lens Compared to a Marketed Monthly Replacement Contact Lens
Randomized, double-masked, controlled, 2-arm parallel group, multi-site, 3-month dispensing study of Johnson \& Johnson Vision Care, Inc.
- Trial name
- NCT02515994
- Testing
- senofilcon C, comfilcon A
- Where
- 10 sites in United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Presbyopia
Compare Visual Outcomes Using a New Diagnostic Device
Evaluation of preoperative corrected distance visual acuity (CDVA) obtained with VirtIOL device compared to postoperative CDVA.
- Trial name
- NCT04037631
- Testing
- Diagnostic device
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- Carl Zeiss Meditec AG
Myopic Astigmatism
Efficacy and Safety of CLEAR in Myopia and Astigmatism in Chinese Population
In this multicenter, prospective, interventional, single-arm clinical trial, the aim is to determine safety and efficacy of CLEAR using the FEMTO LDV Z8 in Chinese patients in China.
- Trial name
- NCT05229133
- Testing
- CLEAR
- Where
- 4 sites in China
- Volunteers
- 215 people
- Sponsor
- Ziemer Ophthalmic Systems AG
Myopia
Safety and Efficacy of a Contact Lens for Daily Disposable Use
This study is to evaluate the safety and efficacy of a new hydrogel daily disposable contact lens compared to the Bausch + Lomb SofLens® daily disposable contact lens when worn by current soft contact lens wearers on a daily…
- Trial name
- NCT01365039
- Testing
- Test, daily disposable contact lens, SofLens daily disposable contact lens
- Where
- United States
- Volunteers
- 173 people
- Sponsor
- Bausch & Lomb Incorporated
Myopia
Lens Wear Schedules and End-of-Day Comfort
The purpose of this study was to assess the impact of lens-free (recovery) intervals of varying lengths on end-of-day comfort and tear film changes with daily contact lens wear.
- Trial name
- INVERMERE (NCT01433549)
- Testing
- Lotrafilcon B, Senofilcon A
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- CIBA VISION
Cataract, Myopia
Effect of TrueTear Corneal Surface Imaging
This study will evaluate the utility of TrueTear™ to improve anterior corneal surface imaging quality before cataract surgery, refractive lens exchange, or laser refractive surgery.
- Trial name
- NCT03637348
- Testing
- TrueTear
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Price Vision Group
Refractive Error
DAILIES TOTAL1® Lubricity Post Wear
The primary objective of the study is to demonstrate that the lubricity of DAILIES TOTAL1® (DT1) lenses after 16 hours of wear is equivalent to the lubricity of unworn DT1 lenses.
- Trial name
- NCT02072980
- Testing
- Delefilcon A contact lenses
- Volunteers
- 15 people
- Sponsor
- Alcon Research
Ametropia, Myopia; Refractive Error
The Objective of This Study is to Evaluate the Perfomance of a Photorefraction Device for Screening Ametropia in Children. Eligible Participants Will Undergo Multiple Refractive Error Measurements, Visual Acuity and Strabismus Assessments During a Single Evaluation Visit.
The goal of this clinical trial is to evaluate the performance of a photorefraction screener in terms of sensibility, sensitivity and accuracy on children aged 3 to 8 y.o.
- Conditions
- Ametropia, Myopia; Refractive Error, Myopia; Astigmatism
- Trial name
- NCT06882408
- Testing
- Photorefraction device under investigation, Comparator device, Tabletop auto-refractometer, Comparator device, portable photorefraction device
- Where
- 2 sites in France
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- Essilor International
Astigmatism
Clinical Evaluation of Invigor Toric 1-Day Contact Lenses
An evaluation of the clinical performance of the 1-day toric test contact lens compared to the 1-day toric control contact lens over one hour of lens wear.
- Trial name
- NCT04016623
- Testing
- 1-day toric test contact lens, 1-day toric control contact lens
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- CooperVision, Inc.
Hyperopia
Safety and Effectiveness of the TENEO 317 Model 2 (1.28 US) Excimer Laser for Laser In Situ Keratomileusis (LASIK) Surgery to Treat Hyperopia With or Without Astigmatism
This will be a multicenter, prospective, open label, non-randomized, single arm 12 month study, evaluating the safety and effectiveness of the TECHNOLAS TENEO 317 Model 2 (Software version "1.28 US") excimer laser when used in…
- Trial name
- NCT05264623
- Testing
- TENEO 317 Model 2 excimer laser
- Where
- 9 sites in United States
- Volunteers
- 140 people
- Sponsor
- Bausch & Lomb Incorporated
Astigmatism
Effect of Eye Movement on Toric Lens Orientation and Visual Acuity
The relative performance of a new toric soft contact lens against toric contact lenses currently available in market, specifically for visual acuity and lens orientation.
- Trial name
- NCT00584831
- Testing
- senofilcon A, balafilcon A, omafilcon A
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia, Astigmatism
CLEAR Procedure in Myopia and Astigmatism - Registry Study
Multicenter, prospective, single-arm, observational, non-interventional post market clinical investigation (registry study) with the overall objective to assess safety and performance of CLEAR in a real world setting.
- Trial name
- NCT05484531
- Testing
- CLEAR
- Volunteers
- 150 people
- Sponsor
- Ziemer Ophthalmic Systems AG
Presbyopia
A Dose-ranging Study to Evaluate the Safety and Efficacy of UNR844 in Subjects With Presbyopia.
Study of safety and efficacy of UNR844 in subjects with presbyopia.
- Trial name
- READER (NCT04806503)
- Testing
- UNR844
- Where
- 20 sites in United States, Australia and 2 more
- Volunteers
- 234 people
- Sponsor
- Novartis Pharmaceuticals
Presbyopia
A Dispensing Clinical Trial of Comfilcon A Extended Range Multifocal Lenses
The aim of this study is to validate the clinical of comfilcon A extended range high add center near (CN) multifocal lenses in existing contact lens wearers against the current comfilcon A high add multifocal lenses.
- Trial name
- NCT02719366
- Testing
- comfilcon A Extended Range test lens, comfilcon A control lens
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.