Clinical trials: Eye--Refractive Errors
Presbyopia
A Safety, Efficacy and Pharmacokinetic Study of AGN-199201 and AGN-190584 in Patients With Presbyopia
This is a safety, efficacy and pharmacokinetics study of the fixed combination of AGN-199201 and AGN-190584 in participants with presbyopia (inability to focus on items close-up).
- Trial name
- NCT02780115
- Testing
- AGN-199201 ophthalmic solution, AGN-190584 ophthalmic solution, AGN-199201 Vehicle
- Where
- 25 sites in United States
- Volunteers
- 151 people
- Sponsor
- Allergan
Hyperopia, Myopia
A Clinical Comparison of Two Soft Contact Lenses (C24-755)
The aim of this study is to compare the short-term clinical performance of two soft contact lenses.
- Trial name
- NCT06758076
- Testing
- Lens 1 (ocufilcon D), Lens 2 (somofilcon A)
- Where
- United Kingdom
- Volunteers
- 52 people
- Sponsor
- CooperVision, Inc.
Myopia
Clinical Investigation of a Novel Spectacle Lens on Slowing Down Juvenile Myopia Progression
The goal of this exploratory clinical trial is to evaluate the efficacy and safety of a test spectacle lens (standard single vision lens (SVL) during first year, and standard myopia control lens (MCL) in second year), designed…
- Trial name
- NCT06850168
- Testing
- SVL, SVL with passive red-light emission, MCL
- Where
- Singapore
- Volunteers
- 35 people
- Sponsor
- Essilor International
Teenagers, Myopia
Visual and Postural Behavior in Myopic and Non-Myopic Teenagers
The goal of this observational study is to learn whether different types of eyeglasses prescription and different types of lenses change how close teenagers hold objects when looking at them up close.
- Trial name
- CALYPSO (NCT07440134)
- Testing
- Ophtalmic measurements, Visuo-postual measurements
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Essilor International
Presbyopia
Clinical Performance of a Phakic Intraocular Lens (IOL)
This study will evaluate the clinical performance of a phakic intraocular lens (IOL) for the improvement of Uncorrected Near Visual Acuity (UCNVA) in subjects who require between +1.00 and +2.50 Reading Add.
- Trial name
- NCT03499821
- Testing
- EDOF ICL
- Where
- 6 sites in Belgium, Spain
- Volunteers
- 41 people
- Sponsor
- Staar Surgical Company
Astigmatism
A Study to Address Precision and Refractive Predictability of Femtosecond Laser-assisted Astigmatic Keratotomy Following the Cataract Surgery
The purpose of this open, prospective study is to address the effectiveness and precision of the VICTUS™ Femtosecond Laser Platform-assisted astigmatic keratotomy after femtolaser-assisted cataract surgery.
- Trial name
- NCT01752218
- Testing
- arcuate incision
- Where
- Germany
- Volunteers
- 43 people
- Sponsor
- Technolas Perfect Vision GmbH
Accommodation Disorder, Keratoconus
Clinical Investigation for a Multifunction Ophthalmic Measurement Device
The purpose of this clinical investigation is to evaluate the clinical utility of a multifunctional measuring device for Ophtalmology.
- Conditions
- Accommodation Disorder, Keratoconus, Dry Eye, Refractive Errors
- Trial name
- NCT06565091
- Testing
- Measurements of physiological parameters of the anterior chamber, Measurements of the Axial biometry
- Where
- France
- Volunteers
- 378 people, healthy volunteers welcome
- Sponsor
- Essilor International
Presbyopia
Bifocal Contact Lens Study for Adults With Age-Related Near Vision Loss
The primary objective of this study is to evaluate the distance, intermediate and near visual performance of Clerio designed single vision and Clerio designed LIRIC modified bifocal lenses (+2.00D add) compared to commercially…
- Trial name
- NCT03653715
- Testing
- Clerio Vision LIRIC-modified Bifocal Contact Lens, Johnson & Johnson 1-Day Acuvue Moist Multifocal Contact Lens, Johnson & Johnson 1-Day Acuvue Moist Contact Lens
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Clerio Vision, Inc.
Myopia, Myopia Progression, Lag of Accommodation, Hyperopic Retinal Blur, Reduction in Contrast
Lag of Accommodation With DOT Spectacle Lenses
The objective of the study is to measure the difference in the lag of accommodation between DOT spectacle lenses and control spectacles.
- Trial name
- ASH (NCT04700111)
- Testing
- DOT Pattern, Control Spectacles
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- SightGlass Vision, Inc.
Myopia
One Month Dispensing Study Comparing the Clinical Performance of the Comfilcon A Sphere Lenses Compared to Comfilcon A Asphere Lenses.
This is a prospective, multi-center, subject-masked, bilateral wear, one month dispensing study comparing the clinical performance of the subjects' habitual comfilcon A sphere lens (control) following a refit with comfilcon A…
- Trial name
- NCT02759471
- Testing
- comfilcon A sphere lens (control), comfilcon A asphere lens (test)
- Where
- 4 sites in United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia
Evaluation of Etafilcon A Daily Disposable Lenses
To evaluate the clinical performance of daily disposable etafilcon A lenses.
- Trial name
- NCT02061592
- Testing
- etafilcon A
- Where
- 7 sites in United States
- Volunteers
- 136 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Aphakia, Cataract
A Clinical Study to Evaluate The Safety and Effectiveness of The RxSight Light Adjustable Lens (LAL) In Subjects Desiring an Extended Depth of Focus
The primary objective of this study is to evaluate, for the visual correction of aphakia and presbyopia, the safety and effectiveness of the RxSight Light Adjustable Lens (LAL) to provide an extended depth of focus (improve…
- Conditions
- Aphakia, Cataract, Presbyopia
- Trial name
- NCT04177771
- Testing
- Light Adjustable lens (LAL) and Light Delivery Device (LDD) - Pre-COVID Population, SofPort LI61AO IOL, Tecnis ZCB00 or ZTC150 IOL
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- RxSight, Inc.
Refractive Error
Corneal Staining Associated With Daily Disposable Beauty Contact Lenses
Limbal ring contact lenses enhance the look of the eye by adding pigmentation in a ring pattern to the contact lens. The purpose of this investigation is to determine if corneal staining increase is dependent upon the lens…
- Trial name
- NCT01882465
- Testing
- etafilcon A, 2-HEMA, EGDMA Non-ionic, hefilcon A
- Where
- Hong Kong
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
Phase 1 Study of SHJ002 Sterile Ophthalmic Solution in Pediatric Subjects
This is a single-center, open-label, first-in-human dose-escalation study of SHJ002 Ophthalmic Solution in children. (Part 1) Three (3) subjects will receive each concentration of SHJ002 for 3 days in an escalation design in one…
- Trial name
- NCT04928144
- Testing
- SHJ - Low concentration, SHJ - Mid concentration, SHJ - High concentration
- Where
- Taiwan
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Sunhawk Vision Biotech, Inc.
Refractive Error, Myopia
Clinical Comparison of DDT2 Contact Lens and a Daily Disposable Contact Lens - Study 2
The purpose of this study was to evaluate visual acuity at distance when wearing DDT2 contact lenses compared to Clariti contact lenses.
- Trial name
- NCT03888482
- Testing
- Verofilcon A contact lenses, Somofilcon A contact lenses
- Where
- 8 sites in United States
- Volunteers
- 154 people
- Sponsor
- Alcon Research
Presbyopia
A Clinical Trial to Evaluate a Corneal Inlay for the Improvement of Near Vision in Presbyopic Patients
This study will be a prospective, multicenter clinical trial in which a total of 400 subjects will be enrolled. All subjects will be followed over a 36 month time frame with a maximum of 15 clinical sites participating.
- Trial name
- NCT01373580
- Testing
- The Raindrop Near Vision Inlay
- Where
- 11 sites in United States
- Volunteers
- 373 people, healthy volunteers welcome
- Sponsor
- ReVision Optics, Inc.
Presbyopia, Refractive Errors
Prospective Multicenter Clinical Study on the Visual and Refractive Outcomes and Safety Outcomes Following Implantation of an AddOn Intraocular Lens in Previously Pseudophakic Eyes
The purpose of this prospective multicenter clinical study is to evaluate the visual and refractive outcomes and safety outcomes following bilateral implantation of trifocal and/or trifocal toric 1stQ AddOn (Medicontur)…
- Conditions
- Presbyopia, Refractive Errors, Residual Astigmatism
- Trial name
- NCT05596682
- Testing
- supplementary intraocular lenses
- Where
- 4 sites in Belgium, France and 2 more
- Volunteers
- 75 people
- Sponsor
- Medicontur Medical Engineering Ltd
Myopia
A Clinical Study to Evaluate the Remote Monitoring of Myopia Patients With the EyeQue Insight
The objective of this study is to determine whether the remote monitoring of myopia patients with the EyeQue Insight (visual acuity test) can replace regularly scheduled follow-up visits.
- Trial name
- NCT04693260
- Testing
- Visual Acuity with a Hand-held Device Supported by Mobile App.
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- EyeQue Corp.
Refractive Error
Fitting Children With Contact Lenses
The purpose of this three-month study is to compare the quality of life and ease of fit among children wearing investigational single-vision contact lenses, commercially marketed single-vision contact lenses, and commercially…
- Trial name
- COPPER (NCT01233089)
- Testing
- Lotrafilcon B contact lens, investigational, Lotrafilcon B contact lens, commercial (AIR OPTIX AQUA), Lotrafilcon B multifocal contact lens, commercial (AIR OPTIX AQUA MULTIFOCAL)
- Where
- Canada
- Volunteers
- 194 people
- Sponsor
- CIBA VISION
Myopia
A Two-Week Crossover Dispensing Evaluation Of Orion Daily Wear Soft Contact Lens
The primary objective of the study is to evaluate the clinical performance of test lens (Orion) in comparison with control lens (Gemini) over a period of two weeks of wear.
- Trial name
- NCT04585646
- Testing
- Orion daily disposable contact lens, Gemini daily disposable contact lens
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.