Clinical trials: Eye--Refractive Errors
Myopia
1 Week Crossover Study Between Two Soft Contact Lenses
The objective of this investigation is to compare the visual clinical performance of two daily disposable soft contact lenses.
- Trial name
- NCT06611410
- Testing
- Test Lenses (stenfilcon A), Control Lenses (omafilcon A)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- CooperVision, Inc.
Presbyopia
Clinical Outcomes of Femtosecond Laser Presbyopia Treatment in Monofocal IOLs
This study aimed to assess the safety and efficacy of treating presbyopia in eyes implanted with a mono focal IOL using a low-energy femtosecond laser.
- Trial name
- NCT07384182
- Testing
- Perfector
- Where
- Czechia
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Perfect Lens, LLC
Astigmatism
Clinical Performance of Atypical Contact Lens Powers on Subjects With Astigmatism
This study will evaluate the fitting characteristics and physiological response of two toric lenses manufactured by Vistakon.
- Trial name
- NCT00697190
- Testing
- senofilcon A toric, galyfilcon A toric
- Where
- United Kingdom
- Volunteers
- 39 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
Dehydration of Stenfilcon A Contact Lenses Versus Delefilcon A Contact Lenses
The study will explore in vivo lens dehydration rates across a 12hr wear period for the study lenses.
- Trial name
- NCT02366923
- Testing
- stenfilcon A, delefilcon A
- Where
- Canada
- Volunteers
- 28 people
- Sponsor
- CooperVision, Inc.
Ametropia
Safety and Efficacy of Different Add Powers With a New Presbyopic Lasik Treatment Algorithm
This is a prospective, comparative, randomized, controlled, open-label, single-surgeon, single-center PMCF clinical study whereby presbyopic patients undergoing refractive surgery will receive a SUPRACOR treatment for the…
- Trial name
- NCT04617080
- Testing
- SUPRACOR Regular, SUPRACOR Strong
- Where
- Philippines
- Volunteers
- 60 people
- Sponsor
- Bausch & Lomb Incorporated
Refractive Error, Myopia
Clinical Performance of a New Daily Disposable Contact Lens Worn in a Neophyte Population.
This study seeks to evaluate the impact of wearing a new daily disposable soft contact lens on the neophyte population.
- Trial name
- NCT00708032
- Testing
- spectacles, narafilcon A soft contact lenses
- Where
- United Kingdom
- Volunteers
- 74 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
Dual Focus Soft Contact Lens Wear Cessation Study
The purpose of this study is to investigate the effect of ceasing treatment with dual focus soft contact lenses.
- Trial name
- NCT05779072
- Testing
- Single Vision Soft Contact Lens
- Where
- 4 sites in Canada, Portugal and 2 more
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia, Astigmatism
Comparative In-Vivo Wetting Characteristics of Silicone Hydrogel Materials With Selected Lens Care Systems
The purpose of this study is to evaluate the lipid uptake, wetting characteristics, and visual performance of AIR OPTIX® AQUA and ACUVUE® OASYS® with HYDRACLEAR® contact lenses when used in conjunction with two contact lens care…
- Conditions
- Myopia, Astigmatism, Refractive Error
- Trial name
- NCT01699750
- Testing
- Lotrafilcon B contact lenses, Senofilcon A contact lenses, OPTI-FREE® PUREMOIST® MPDS
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- Alcon Research
Myopia
Influence of Rodenstock Spectacle Lenses on Myopia Progression.
The prevalence of myopia in Singapore is among the highest in the world, with 65 percent of our children being myopic by Primary 6, and 83 percent of young adults being myopic.
- Trial name
- NCT06816446
- Testing
- Myopia control spectacle lens, Single-vision lens
- Where
- Singapore
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- Rodenstock GmbH
Myopia
Vistakon Investigational Contact Lenses Worn for Daily Wear
This study compares the performance of an investigational contact lens to a currently marketed lens.
- Trial name
- NCT00717249
- Testing
- galyifilcon A control lens, galyfilcon A with a silver additive
- Where
- 20 sites in United States
- Volunteers
- 529 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Astigmatism
Non-dispensing Study to Check Prescription Equivalence of Two Daily Disposable Toric Contact Lens Types
The purpose of this study is to determine whether the prescription determined for a new daily disposable toric contact lens will be a good match to a prescription determined for an existing brand of lens.
- Trial name
- NCT01120782
- Testing
- etafilcon A toric contact lens with new wetting agent, etafilcon A toric contact lens
- Where
- 2 sites in United States
- Volunteers
- 45 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia, Hyperopia
A Prospective Safety and Effectiveness Study of the 500 Hz Technolas Perfect Vision Excimer Laser Using LASIK
This clinical study has been planned to evaluate the safety and effectiveness of a common treatment algorithms (Proscan) using 500 Hz laser repetition rate.
- Trial name
- NCT02071576
- Testing
- Proscan
- Where
- China
- Volunteers
- 42 people
- Sponsor
- Technolas Perfect Vision GmbH
Myopia
Evaluating the Efficacy and Safety of Contact Lens Lubricant in Rigid Gas Permeable Corneal Contact Lens Wearers
This trial aims to evaluate the safety and effectiveness of LACRIFRESH OCU-DRY 0.3% OSD, a contact lens lubricant produced by AVIZOR, S.A.
- Trial name
- NCT07091825
- Testing
- LACRIFRESH OCU-DRY 0.3% OSD, Rigid contact lens lubricant
- Where
- 3 sites in China
- Volunteers
- 152 people
- Sponsor
- Avizor SA
Myopia
An Evaluation of the Effectiveness of Dual Focus Soft Contact Lenses in Slowing Mypoia Progression
The purpose of this study is to determine whether a new type of soft contact lens with a unique optical design (dual focus) is effective at slowing the progression of myopia (near-sightedness) in children.
- Trial name
- NCT01729208
- Testing
- Dual Focus Soft Contact Lens, Single Vision Soft Contact Lens
- Where
- 4 sites in Canada, Portugal and 2 more
- Volunteers
- 144 people
- Sponsor
- CooperVision, Inc.
Myopia, Astigmatism
Post-approval Study of New Enrolment Patients Undergoing Bilateral Treatment With the VisuMax SMILE Procedure
The objective of the post-approval study (PAS) is to assess patient experience of visual symptoms 6 months after bilateral treatment with the VisuMax SMILE procedure as measured by a patient questionnaire.
- Trial name
- NCT05740293
- Testing
- VisuMax SMILE procedure for the reduction or elimination of myopia with astigmatism
- Where
- 7 sites in United States
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec, Inc.
Astigmatism
Quantification of the Visual Benefits of Soft Toric Contact Lenses Compared to Soft Spherical Contact Lenses
The aim of this work is to undertake a range of vision-related measures with soft toric contact lenses soft spherical contact lenses and spectacle lens correction across a range of levels of astigmatism.
- Trial name
- NCT04613882
- Testing
- Soft Toric Custom Made Contact lens, Soft Spherical Contact Lenses, Spectacle Correction
- Where
- United Kingdom
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Refractive Error, Presbyopia
Clinical Evaluation of DAILIES TOTAL 1® Multifocal Compared to 1-Day Acuvue® Moist® Multifocal in a Japanese Population
The purpose of this clinical study is to evaluate DAILIES TOTAL1® Multifocal (DT1MF) contact lenses compared to 1-DAY ACUVUE® Moist® Multifocal (AMMF) contact lenses for investigator-graded lens centration in a Japanese…
- Trial name
- NCT03341923
- Testing
- Delefilcon A multifocal contact lenses, Etafilcon A multifocal contact lenses
- Where
- 4 sites in Japan
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Myopia
Myopia Control With Novel Eye Drops
Myopia currently affects 30% of the world and by 2050, almost 50% of the world will be myopic based on conservative estimates.1 In 2050, this will equate to almost 5 billion people with myopia, and those with high myopia will…
- Trial name
- NCT04301323
- Testing
- BHVI1 eye drops, BHVI2 eye drops, BHVI3 eye drops
- Where
- Vietnam
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Hai Yen Eye Care
Myopic Astigmatism
A Study to Investigate the Safety and Effectiveness of the Technolas® TENEO 317 Model 2 Excimer Laser for Laser In Situ Keratomileusis (LASIK) Surgery to Treat Myopia or Myopic Astigmatism
This will be a multicenter, prospective, open label, non-randomized, single arm study evaluating the safety and effectiveness of the Technolas® TENEO 317 Model 2 (version 1.28 US software) Excimer Laser when used in LASIK surgery…
- Trial name
- NCT07377474
- Testing
- TENEO 317 Model 2 (1.28 US) Excimer Laser
- Volunteers
- 32 people
- Sponsor
- Bausch & Lomb Incorporated
Presbyopia
A Study to Assess Safety and Efficacy in Participants Age 40 to 55 With Presbyopia (Old Eye) Who Receive AGN-190584 in Both Eyes Twice Daily
Currently available treatments for presbyopia (old eye) include nonsurgical options (spectacles or contact lenses) and surgical options, however, each has its own risks and limitations.
- Trial name
- Virgo (NCT04983589)
- Testing
- Pilocarpine HCl, Vehicle
- Where
- 23 sites in United States
- Volunteers
- 230 people
- Sponsor
- Allergan