Clinical trials: Eye--Refractive Errors
Refractive Errors
Clinical Performance of Two Daily Disposable Soft Contact Lenses
The purpose of this study is to compare the clinical performance of PRECISION1 contact lenses with Biotrue contact lenses.
- Trial name
- NCT05138783
- Testing
- Verofilcon A contact lenses, Nesofilcon A contact lenses
- Where
- 8 sites in United States
- Volunteers
- 129 people
- Sponsor
- Alcon Research
Myopia, Hyperopia
The Effect of Masking on Subjective Results During Daily Disposable Contact Lens Studies
The purpose of this study is to explore the effect of masking on subjective ratings for two daily disposable contact lenses.
- Trial name
- ARGON (NCT01155726)
- Testing
- Nelfilcon A contact lens, Nelfilcon A contact lens with comfort additive (DACP), unmasked, Nelfilcon A contact lens with comfort additive (DACP), masked
- Where
- Canada
- Volunteers
- 134 people
- Sponsor
- CIBA VISION
Myopia
Daily Wear Comparison of Enhanced and Non-Enhanced Silicone Hydrogel Lenses
The purpose of this study is to compare an experimental contact lens with a currently marketed contact lens.
- Trial name
- NCT00813982
- Testing
- Lotrafilcon A Experimental Contact Lens, Lotrafilcon A Commercial Contact Lens
- Volunteers
- 60 people
- Sponsor
- CIBA VISION
Refractive Errors, Myopia
Clinical Comparison of 2 Daily Disposable Contact Lenses - Pilot Study 1
The primary objective of this study is to evaluate the overall performance of PRECISION1 contact lenses when compared to Biotrue ONEday contact lenses.
- Trial name
- NCT04527978
- Testing
- Verofilcon A contact lenses, Nesofilcon A contact lenses
- Where
- 4 sites in United States
- Volunteers
- 56 people
- Sponsor
- Alcon Research
Refractive Errors, Myopia
Clinical Comparison of 2 Daily Disposable Contact Lenses - Pilot Study 2
The primary objective of this study is to evaluate the overall performance of PRECISION1 contact lenses when compared to Clariti 1-Day contact lenses.
- Trial name
- NCT04528017
- Testing
- Verofilcon A contact lenses, Somofilcon A contact lenses
- Where
- 4 sites in United States
- Volunteers
- 56 people
- Sponsor
- Alcon Research
Presbyopia
A Clinical Comparison of Two Soft Multifocal Contact Lenses
The study objective was to gather short-term clinical performance data for two soft multifocal contact lenses.
- Trial name
- NCT05794126
- Testing
- Lens 1, Lens 2
- Where
- United Kingdom
- Volunteers
- 47 people
- Sponsor
- CooperVision, Inc.
Ametropia
Performance of Toric Hydrogel Lenses Following A Refit With Toric Silicone Hydrogel Lenses for 1 Month
The aim of this prospective study is to evaluate the clinical performance of habitual wearers of methafilcon A toric lenses after a refit with fanfilcon A toric lenses for 1-month of daily wear.
- Trial name
- NCT03835221
- Testing
- methafilcon A toric contact lenses, fanfilcon A toric contact lenses
- Where
- Mexico
- Volunteers
- 43 people
- Sponsor
- CooperVision, Inc.
Ametropia
A Clinical Study of the Comfilcon A Asphere Soft Contact Lens in Users of Digital Devices
The aim of this work is to investigate the clinical performance and subjective acceptance of the comfilcon A asphere contact lens when compared to single-vision spectacles in subjects who have never worn contact lenses and who…
- Trial name
- NCT04067050
- Testing
- comfilcon A asphere, Spectacles
- Where
- United Kingdom
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Cataract, Corneal Astigmatism
ClarVista HARMONI Toric Trial With Intraoperative Exchange
The purpose of this study was to demonstrate the safety and effectiveness of the HARMONI® Modular Intraocular Lens System with a toric optic in subjects with pre-existing corneal astigmatism in need of cataract surgery.
- Conditions
- Cataract, Corneal Astigmatism, Aphakia
- Trial name
- NCT03054649
- Testing
- HARMONI® Modular Intraocular Lens System, Intraoperative optic exchange
- Where
- 2 sites in Mexico, Philippines
- Volunteers
- 44 people
- Sponsor
- ClarVista Medical
Astigmatism, Myopia
Vision Stability and Preference for Soft Toric vs. Soft Spherical Contact Lenses
The principal hypothesis is to be tested in this work is that vision stability (the primary outcome measure) with a spherical contact lens correction vs. a toric contact lens correction will be the same.
- Trial name
- NCT04536571
- Testing
- Test Contact lens, Control Contact lens
- Where
- United Kingdom
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Refractive Errors, Ametropia
Clinical Biocompatibility Evaluation of Contact Lens Coatings
The primary objective is to evaluate corneal staining observed after 2 hours of wear with contact lenses with investigational coating against PureVision™ lenses, all pre-cycled with OPTI-FREE® RepleniSH® multi-purpose…
- Trial name
- NCT03034928
- Testing
- Contact lens with investigational coating 1, Balafilcon A contact lens, OPTI-FREE® RepleniSH® MPDS
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Alcon Research
Myopia, Hyperopia
Accuracy of LASIK Flaps Created With the LenSx® Femtosecond Laser - A Pilot Study
The purpose of this study is to evaluate the thickness accuracy of Laser-assisted in situ keratomileusis (LASIK) flaps created with the LenSx® Laser.
- Trial name
- NCT02575911
- Testing
- Femtosecond Laser System, LASIK surgery
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Alcon Research
Presbyopia
Somofilcon A 1-Day Multifocal Study - Real World Subjective Acceptance Study
The objective of the study is to evaluate the performance of somofilcon A 1 day multifocal when worn on a daily disposable wear modality over a period of up to 3 weeks.
- Trial name
- NCT03519919
- Testing
- somofilcon A multifocal lens
- Where
- Canada
- Volunteers
- 51 people
- Sponsor
- CooperVision, Inc.
Presbyopia
1-Week Dispensing Evaluation of Kalifilcon A Daily Disposable Multifocal Compared to Ultra for Presbyopia
Experienced soft contact lens wearing subjects will be enrolled in this 1-week, confirmatory, randomized, bilateral, 2-way crossover, double masked (subject and investigator), repeated measures, dispensing study.
- Trial name
- NCT05325931
- Testing
- kalifilcon A Daily Disposable Multifocal, samfilcon A for Presbyopia
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Ametropia
Comparison of Two Toric Contact Lenses on Current Toric Wearers
The purpose of this study is to evaluate and compare the clinical performance of two toric contact lenses amongst 110 subjects, 2-week, single masked (subject), daily wear, randomized, bilateral, crossover study; 4 weeks…
- Trial name
- NCT00639379
- Testing
- senofilcon A toric, alphafilcon A toric
- Where
- 7 sites in United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
Evaluation of a New Silicone Hydrogel Contact Lens
The objective of this study is to determine the clinical feasibility and to evaluate the product performance of investigational contact lenses developed by Bausch + Lomb.
- Trial name
- NCT01309880
- Testing
- Test lens, Air Optix Aqua
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Myopia
Clinical Evaluation of Hydrogels vs Silicone Hydrogel Contact Lenses
The aim of this fitting study is to evaluate the clinical performance of different hydrogel and silicone hydrogel contact lenses.
- Trial name
- NCT01966770
- Testing
- Pair 1 (ocufilcon D / ocufilcon D), Pair 2 (ocufilcon D / enfilcon A), Pair 3 (ocufilcon D / comfilcon A)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- CooperVision, Inc.
Refractive Error
Tear Film Evaluation of Dailies® AquaComfort Plus® Multifocal and Toric
The purpose of this study is to evaluate the pre lens tear film characteristics of DAILIES® Aqua Comfort Plus® Multifocal (DACP MF) and Toric (DACP Toric) compared to DAILIES® Aqua Comfort Plus® Sphere (DACP) daily disposable…
- Trial name
- NCT02289742
- Testing
- Nelfilcon A multifocal contact lenses, Nelfilcon A toric contact lenses, Nelfilcon A sphere contact lenses
- Volunteers
- 48 people
- Sponsor
- Alcon Research
Presbyopia, Astigmatism
Clinical Performance Evaluation of Two Frequent Replacement Silicone Hydrogel Multifocal Toric Contact Lenses
The purpose of this study is to evaluate on-eye clinical performance of the investigational contact lenses following 30 days of wear in the intended population.
- Trial name
- NCT06461455
- Testing
- Lehfilcon A multifocal for astigmatism contact lenses, Samfilcon A multifocal for astigmatism contact lenses, CLEAR CARE® Cleaning & Disinfecting Solution
- Where
- 11 sites in United States
- Volunteers
- 95 people
- Sponsor
- Alcon Research
Astigmatism
Success of Dailies Total1 for Astigmatism Contact Lenses in Patients That Have Previously Failed With Toric Contact Lenses
The objective is to determine the percentages of past toric CL wearers (who dropped out of contact lens wear due to dissatisfaction with comfort or vision) who are satisfied with the comfort and vision of DT1fA contact lenses.
- Trial name
- NCT05886452
- Testing
- DT1fA contact lenses
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Mann Eye Institute