Clinical trials: FMT
Alzheimer Disease
Oral Fecal Microbiota Transplant Feasibility Study in Alzheimer's Disease
The goal of this study is to assess the safety and feasibility of an oral fecal microbiota transplant (FMT) intervention for Alzheimer's disease (AD).
- Trial name
- AMBITION (NCT03998423)
- Testing
- Fecal Microbiota Transplant
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Acute-graft-versus-host Disease
FMT in Gut aGVHD Treated
With the stem cell transplanting increasing, patients which effected with gut GVHD were also increased. To evaluation the safety and efficacy of FMT for gut GVHD,patients with gut GVHD were recruited.
- Trial name
- NCT03148743
- Testing
- Fecal microbiota
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Soochow University
Ulcerative Colitis
Fecal Microbiota Transplantation (FMT) for Treatment of Ulcerative Colitis in Children
Patients diagnosed with ulcerative colitis (UC), a specific type of inflammatory bowel disease, will be invited to take part in this study. The investigators do not know what causes UC.
- Trial name
- FMT (NCT01947101)
- Testing
- Fecal Microbiota Transplant
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Physical Abilities, FMT
Assessing the Potential Role of the Gut Microbiome in Modulating Physical Abilities in Humans
The intestinal microbiome is a microbial system that is influenced by host genetics and environmental exposures such as nutrition, stress and medications.
- Trial name
- NCT05024188
- Testing
- Antibiotics, Autologous Fecal Microbiota Transplantation, Cellules Pills
- Where
- Israel
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Anorexia Nervosa, Microbiome Dysbiosis
Feasibility Study of Using Fecal Microbiota Transplants in Anorexia Nervosa
The investigators hypothesize that prolonged undernutrition in anorexia nervosa alters the microbiome to a different steady-state (dysbiotic) composition that sustains the disease, even after returning to normal diet.
- Trial name
- ReBoot (NCT05834010)
- Testing
- Fecal Microbiome Transplant
- Where
- 3 sites in Denmark
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Ulcerative Colitis
Restoration of the Microbiome Through Superdonor Selection
The AIM of this study is to investigate whether the FMT success rate in active UC patients can be increased by intensive donor pre-screening, anaerobic preparation of the FMT and by repeated FMT.
- Trial name
- RESTORE-UC (NCT03110289)
- Testing
- superdonor FMT, autologous FMT
- Where
- Belgium
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Irritable Bowel Syndrome
Fecal Microbial Transplantation in Treatment of Irritable Bowel Syndrome; a Double Blinded Placebo Controlled Trial.
Fecal Microbial Transplantation in Treatment of Irritable Bowel Syndrome; a Double Blinded Placebo Controlled Trial - the REFIT project Irritable bowel syndrome (IBS) is a condition characterized by variable complaints like…
- Trial name
- REFIT (NCT02154867)
- Testing
- Fecal transplantation
- Where
- Norway
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University Hospital of North Norway
Crohn Disease
Fecal Microbiota Transplantation as the First-line Treatment in Active Pediatric Crohn's Disease
To explore the safety and effectiveness of repeated and multiple fecal microbiota transplantations (FMTs) plus partial enteral nutrition (PEN) as a first-line treatment for active Crohn's disease (CD) in children.
- Trial name
- FMT (NCT05321758)
- Testing
- Fecal Microbiota Transplantation, Immunosuppressive Agents
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tongji Hospital
Enterobacteriaceae Infections, Fecal Microbiota Transplantation
Pilot Study Using Oral Capsule FMT to Decolonize GI CRE
Carbapenem-Resistant Enterobacteriaceae (CRE) are bacteria that have become resistant to carbapenems by producing enzymes that break down carbapenems.
- Trial name
- NCT03527056
- Testing
- Fecal Microbiota Transplantation
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Biliary Atresia
Gut Microbiome in Biliary Atresia
The investigator will investigate the gut-microbiome and liver elasticity of the Biliary Atresia (BA)-patients before and after Kasai operation.
- Trial name
- NCT04260503
- Testing
- Monitoring of the gut-microbiome and ultrasound elasticity., Monitoring of the gut-microbiome, Monitoring of the gut-microbiome.
- Where
- South Korea
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Yonsei University
ADHD, ADHD - Attention Deficit Disorder With Hyperactivity
A Clinical Trial Evaluating Fecal Microbiota Transplantation (FMT) in Adolescents With ADHD
The primary goals of this phase 2 clinical trial are to determine the feasibility, safety, and tolerability of oral Fecal Microbiota Transplantation (FMT) in adolescents (aged 13-17) with Attention-Deficit/Hyperactivity Disorder…
- Conditions
- ADHD, ADHD - Attention Deficit Disorder With Hyperactivity, ADHD - Combined Type
- Trial name
- FMT-ADHD-2026 (NCT07756255)
- Testing
- Fecal Microbiota Transplant (FMT), Nitazoxanide 500mg BID, Vancomycin 250mg BID
- Where
- Canada
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Clostridium Difficile Colitis
Stool Transplant in Pediatric Patients With Recurring C. Difficile Infection
The incidence of C. difficile infection (CDI) has alarmingly increased over the past several years and the affected population has expanded to include those previously at low risk, such as children.
- Trial name
- NCT01972334
- Testing
- FMT
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- MemorialCare Health System
Diabetes Mellitus, Type 2, Obesity
Fecal Microbiota Transplantation for Diabetes Mellitus Type II in Obese Patients
The incidence of obesity has dramatically increased during the last three decades, leading to a significant increase of obesity-related morbidity, including type 2 diabetes mellitus (T2DM) that is characterized by resistance of…
- Trial name
- NCT02346669
- Testing
- gastroscopy, Fecal Microbiota Transplantation, high fat low fiber diet
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Recurrent Urinary Tract Infection
Fecal Microbiota Transplantation for the Treatment of Recurrent Urinary Tract Infections
Recurrent urinary tract infections are quickly becoming a public health obstacle in our aging population. Almost 50% of women have at least one urinary tract infection in their lifetime; following this first infection, there is a…
- Trial name
- NCT03050515
- Testing
- Fecal Microbiota Transplantation
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Diverticulitis, Uncomplicated Diverticular Disease
FMT in Uncomplicated Diverticulitis
Fecal Microbiota Transplantation (FMT) is an established treatment for Clostridium difficile (C. diff) infection refractory to medical management. As C.
- Trial name
- NCT05373784
- Testing
- Fecal Microbiota Transplantation (FMT)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Justin Maykel
Alcohol Use Disorder (AUD), Alcohol Abstinence
Investigation of the Gut-Brain Axis in Alcohol Use Disorder
A non-profit study involving patients with moderate-to-severe Alcohol Use Disorder (AUD), designed to investigate whether correcting intestinal dysbiosis through Fecal Microbiota Transplantation (FMT) from healthy abstinent…
- Trial name
- FMT-ACT (NCT07902635)
- Testing
- Fecal Microbiota Transplantation (FMT) Procedure and Cognitive Behavioral Therapy (CBT) Procedure
- Where
- Italy
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Autism Spectrum Disorder, Gastrointestinal Diseases
Fecal Microbiota Transplantation for Patients With Autism Spectrum Disorder.
This study aims to evaluate the efficacy of fecal microbiota transplantation on the gastrointestinal symptoms, autistic symptoms and emotional behavior symptoms of patients with autism spectrum disorder, and investigate the…
- Conditions
- Autism Spectrum Disorder, Gastrointestinal Diseases, Healthy
- Trial name
- NCT06290258
- Testing
- Fecal microbiota transplantation
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Pancreatic Cancer, Microbiota
Microbiota and Pancreatic Cancer Cachexia
This monocentric study aims at evaluating the effects of fecal microbiota transplantation from newly diagnosed cachectic and non-cachectic pancreatic cancer patients, and healthy volunteers on several cachexia-related parameters…
- Conditions
- Pancreatic Cancer, Microbiota, Cachexia
- Trial name
- EXTRA (NCT05606523)
- Where
- Switzerland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Genton Graf Laurence
Parkinson Disease
Fecal Microbiota Transplantation As a Potential Treatment for Parkinson's Disease
this pilot study aims to further explore the potential usage of Fecal microbiota transplantation in treating constipation and possibly also motor symptoms in Parkinson's disease (PD) patients, and to increase understanding of the…
- Trial name
- NCT03876327
- Testing
- fecal microbial transplantation
- Where
- Israel
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Obesity, Weight Loss
The Role of Microbiome in Recurrent Obesity
This past century witnessed a significant increase in the prevalence of obesity, when since 1980 worldwide obesity has more than doubled.
- Conditions
- Obesity, Weight Loss, FMT
- Trial name
- NCT05002153
- Testing
- Fecal microbiota transplantation (FMT)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Assaf Harofeh MC