Clinical trials: Facet Joint Syndrome
Low Back Pain, Recurrent, Neuropathic Pain
CRF vs WCRF or PRF-DRG in CLBP of FJ Origin and RFA Failure of MBDR: Central Sensitization and Aberrant Nerve Sprouting
The investigators will select two study groups from a population of patients with severe chronic low back pain (CLBP) of facet joint (FJ) origin already treated with conventional radiofrequency ablation (CRFA) of the medial…
- Conditions
- Low Back Pain, Recurrent, Neuropathic Pain, Facet Joint Pain, Central Sensitisation
- Trial name
- NCT04542798
- Testing
- Radiofrequency COSMAN
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Hospital General Universitario de Valencia
Lumbar Facet Joint Pain
MR Guided High Intensity Focused Ultrasound for Lumbar Back Pain
The primary purpose of this protocol is to assess the ExAblate 2100 MR guided high intensity focused ultrasound device as an intervention for treatment of facetogenic lower back pain.
- Trial name
- NCT02291978
- Testing
- ExAblate 2100
- Where
- United States
- Sponsor
- Stanford University
Back Pain
Effects of Pelvic Tilt Exercises With and Without Facet Joint Manipulation in Patients With Maigne's Syndrome
The aim of this study is to find the effectiveness of exercise therapy and manipulative therapy for patients with maigne's syndrome.
- Trial name
- NCT05052060
- Testing
- Group A, Group B
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Facet Syndrome of Lumbar Spine
Safety and Initial Feasibility of Using the Neurolyser XR Device for the Treatment of Axial Chronic Low Back Pain
Single arm pilot study to evaluate the safety and initial feasibility of the Neurolyser XR, a high intensity focused ultrasound device, for non-invasive treatment of axial chronic low back pain
- Trial name
- NCT04129034
- Testing
- Neurolyser XR
- Where
- 5 sites in Canada
- Volunteers
- 30 people
- Sponsor
- FUSMobile Inc.
Lower Back Pain, Facet Joint Pain; Low Back Pain
Bone Enhanced Ultrasound (BEUS) Data Library Development Project
A common treatment for low back pain involves fluoroscopy-guided spinal facet joint injections and/or medial branch nerve blocks.
- Conditions
- Lower Back Pain, Facet Joint Pain; Low Back Pain, Osteoarthritis (OA)
- Trial name
- NCT07036653
- Testing
- spinal ultrasound
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Queen's University
Lower Back Pain of Disc Origin, Joint Facet Syndrome
Long-Term Evaluation of the Performance and Safety of the IntraSPINE® Interlaminar Implant in the Treatment of Lumbar Degenerative Disc Disease
This is an observational study designed as an extension of a prospective study conducted between 2012 and 2017. Patients who were originally enrolled in the initial study are being recontacted for follow-up assessment, including…
- Conditions
- Lower Back Pain of Disc Origin, Joint Facet Syndrome, Lumbar Canal Stenosis, Spinal Disease
- Trial name
- IntraLT (NCT07790328)
- Testing
- IntraSPINE
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Cousin Biotech
Facet Joint Pain, Arthropathy
Effect of Post-Radiofrequency Corticosteroid Injection on the Incidence of Post-Neurotomy Neuritis
The purpose of this study is to compare the incidence of post-neurotomy neuritis (PNN) in adult patients undergoing radiofrequency neurotomy (RFN) for spine facet and sacroiliac joint pain, comparing those who receive a local…
- Conditions
- Facet Joint Pain, Arthropathy, Sacroiliac Joint Dysfunction, Post-neurotomy Neuritis
- Trial name
- PNN (NCT07839195)
- Testing
- Dexamethasone, Normal Saline, Bupivacaine
- Where
- Thailand
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Siriraj Hospital
Low Back Pain
FDG PET/MRI Evaluation of Facet Joint Pain
Chronic pain incurs over half a trillion dollars in lost productivity (healthcare, lost wages, etc) annually. The most common source is low back pain (LBP), often from facet joints.
- Trial name
- NCT02921490
- Testing
- FDG PET/MR examination.
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Mayo Clinic
Low Back Pain
A Trial of Cooled Radiofrequency Ablation of Medial Branch Nerves for theTreatment of Lumbar Facet Syndrome
This study is being done to determine whether cooled radiofrequency ablation (CRFA) on the medial branch nerves of the lumbar facet joint is effective for the treatment of low back pain.
- Trial name
- STU00097239 (NCT02478437)
- Testing
- Conventional radiofrequency ablation (RFA), Cooled Radiofrequency Ablation (CRFA)
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Northwestern University
Facet Joint Syndrome
Multifidus Muscle Twitch on the Prognosis of Lumbar Medial Branch RF
The investigators collected data and chart from the patients who were diagnosed facet joint syndrome and underwent lumbar RF medial branch neurotomy between January 2009 and June 2014.
- Trial name
- NCT02580383
- Testing
- Radiofrequency neurotomy of lumbar medial branch
- Where
- South Korea
- Volunteers
- 68 people
- Sponsor
- Severance Hospital
Chronic Lower Back Pain, Lumbar Facet Syndrome
A Trial of Intravenous Paracetamol vs. Placebo in Patients Receiving Radiofrequency Ablation of the Medial Branch Facet Nerve
A double blinded randomized controlled study comparing pre-procedural IV Paracetamol versus IV placebo (normal saline). The patients will be randomized to either receiving IV paracetamol or saline infusions before undergoing…
- Trial name
- NCT02539979
- Testing
- Paracetamol
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Facet Joint Pain; Low Back Pain
Sidekick vs Conventional Cannula in Lumbar Medial Branch Radiofrequency Ablation
Lumbar facet joint-mediated chronic low back pain is a common cause of disability. Radiofrequency ablation (RFA) of the lumbar medial branches is an established interventional pain treatment.
- Trial name
- SIDE-RFA (NCT07475689)
- Testing
- Lumbar Medial Branch Radiofrequency Ablation, Triamcinolone (20 g), bupivacain 0.5% 2ml
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Facet Joint Pain, Back Pain
Safety and Efficacy of XT-150 for Facet Joint Osteoarthritis Pain
This is a Phase 2a safety and efficacy study of XT-150 in adult participants experiencing back pain due to inflammation of the facet joint, also known as facet joint osteoarthritis (FJOA), and who are eligible for intra articular…
- Conditions
- Facet Joint Pain, Back Pain, Inflammation
- Trial name
- NCT05196919
- Testing
- XT-150
- Where
- 3 sites in United States
- Volunteers
- 75 people
- Sponsor
- Xalud Therapeutics, Inc.
Chronic Low-back Pain, Facet Joint Pain
Cryoneurolysis Outcome on Pain Experience (COPE) in Patients With Low-back Pain
This study will provide information on the effectiveness of cryoneurolysis for patients with facet joint pain syndrome, and help to establish whether cryoneurolysis should be implemented in clinical practice for this patient…
- Conditions
- Chronic Low-back Pain, Facet Joint Pain, Degeneration Lumbar Spine, Facet Joint Syndrome
- Trial name
- COPE (NCT04786145)
- Testing
- Cryoneurolysis, Radiofrequency ablation
- Where
- Denmark
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Facet Joint Pain
The Cervical Trident Study
This observational retrospective study evaluates the efficacy of RF with the three-tined expandable electrode needle compared to before treatment in the treatment of chronic cervical facet joint pain.
- Trial name
- NCT05353465
- Testing
- Radiofrequency denervation of the cervical facet joint
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Ospedale Regionale di Lugano
Neck Pain, Low Back Pain
The Effect of Radiofrequency-treatment on Patients With Facet-joint Pain in Cervical- and Lumbar-columna
There is conflicting evidence on whether radio-frequency neurotomy of the medial branch has a significant effect on pain in patients with chronic unilateral facet joint neck and back pain.
- Trial name
- NCT00476684
- Testing
- radiofrequency treatment
- Where
- Norway
- Volunteers
- 28 people
- Sponsor
- Norwegian University of Science and Technology
Chronic Low Back Pain
F-18 Sodium Fluoride PET/CT Guided Versus Ultrasound- Guided Intra-articular Injections in Chronic Low Backache
The goal of this open-label randomized controlled trial explored the efficacy of ultrasound guided versus F-18 Sodium Fluoride PET/CT guided local anesthetic and steroid injections in managing chronic low back pain caused by…
- Trial name
- PET-FACET (NCT07632508)
- Testing
- intra-articular injection
- Where
- India
- Volunteers
- 40 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Lumbar Facet Joint Pain, Lumbar Medial Branch Neurotomy
Analgesic Effect of Different Positions and Canulae on Medial Branch Radiofrequency Denervation for Lumbar Zygapophyseal Joint Pain
Prospective study to analyse pain reduction with two types of canulae and two types of placements for lumbar medial branch radiofrequency denervation.
- Trial name
- EARL (NCT03491618)
- Testing
- PAIN REDUCTION ON VAS/NRS
- Where
- Spain
- Volunteers
- 43 people
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Chronic Low-back Pain
Cooled RFA vs Conventional RFA to Manage Chronic Facetogenic Low Back Pain
This study is being conducted to assess the relative effectiveness of radiofrequency neurotomy in subjects with chronic axial low back pain originating in the lumbar facet joints using the COOLIEF* Cooled Radiofrequency Probe as…
- Trial name
- Lumbar CvS (NCT04803149)
- Testing
- Cooled Radiofrequency, Conventional Radiofrequency
- Where
- 10 sites in United States
- Volunteers
- 79 people
- Sponsor
- Avanos Medical
Low Back Pain, Mechanical, Spinal Stenosis
Investigation of Hypermobility, Biomarkers, and Pain Generators in Chronic Pain Patients
Observational study of axial spine pain and hyperflexibility. Patients will receive physical exam maneuvers (traditional straight leg raise, FABER, facet loading as well as Beighton's hypermobility score) and blood / urine /…
- Conditions
- Low Back Pain, Mechanical, Spinal Stenosis, Nerve Root Disorder, Radiculopathy, Cervical
- Trial name
- Hypermoble (NCT02761928)
- Testing
- Beighton score for hypermobility
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- The University of Texas Health Science Center, Houston