Clinical trials: Facial Deformity
Cutis Laxa Facialis, Xeroderma
Trial Assessing the Impact on Facial Skin Quality, Hydration, and Skin Barrier of Three (3) Hydrafacial Treatments in Adults of All Skin Types.
This is a phase IV, unblinded, open-label study assessing the impact on skin quality, hydration, and barrier of three (3) Hydrafacial treatments in healthy adults of Fitzpatrick Skin Types I \& II, III, IV, V \& VI, 30 to 55…
- Trial name
- NCT05932732
- Testing
- HydraFacial Syndeo System, ReGen-GF, HydraFacial Elite MD System
- Where
- 2 sites in United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Austin Institute for Clinical Research
Hyperpigmentation
Fat Grafting an Ideal Filler For Contour Deformities With Hyperpigmentation On Face
Pigmentary changes are commonly associated with contour defects of facial region. These deformities cause cosmetic concerns. Traditionally used techniques indwelling limitations and therefore it invokes innovative techniques to…
- Trial name
- NCT06103461
- Testing
- Autologous fat grafting
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- King Edward Medical University
Skin Laxity, Wrinkle
Evaluation of Efficacy and Safety of the triLift™ System
Single center, single-arm, prospective, open Label with Before \& After Study Design.
- Trial name
- LUM-triLift (NCT05773924)
- Testing
- triLift system
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Lumenis Be Ltd.
Maxillofacial Trauma, Face Cancer
Evaluation of Using 3D Printed PEEK Facial Implants in Repairing Maxillofacial Deformities
Objective: Evaluation of using 3D printed polyether ether ketone facial implants in repairing maxillofacial deformities. Research materials and methods: The research sample consisted of 10 patients with facial deformities…
- Conditions
- Maxillofacial Trauma, Face Cancer, Mucormycosis
- Trial name
- NCT05348434
- Testing
- 3D printed polyether ether ketone facial implants in repairing maxillofacial deformities
- Where
- Syria
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Latakia University
Lymphatic Malformations
Bleomycin Intralesional Injections of Cystic Hygromas
Thirty pediatric patients with cystic hygromas participated in this study. The cystic fluid was aspirated from the cystic hygroma, and the lesion was simultaneously injected with Bleomycin.
- Trial name
- NCT07189832
- Testing
- Intralesional Injections
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Delta University for Science and Technology
X Linked Hypohidrotic Ectodermal Dysplasia
Phenotypic Properties in Individuals Affected With XLHED
The current study design incorporates two previously developed, non-invasive approaches to characterize the phenotype of individuals affected with XLHED.
- Trial name
- ECP-014 (NCT01871714)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Edimer Pharmaceuticals
Cleft Lip and Palate, Unilateral Cleft Lip
Influence of Presurgical Orthodontic Molding on the Growth of Newborns With Unilateral Cleft Lip Palate
Orofacial clefts are the second most common birth deformity and vary in etiology and phenotype, e.g. isolated cleft palate, cleft lip or cleft lip palate.
- Trial name
- NCT05081258
- Testing
- passive Alveolar Molding, Nasoalveolar Molding
- Where
- Germany
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg
Skin Laxity
Ultherapy® for Treating the Face and Neck Using Standard Versus Simulines Transducers
Up to 40 participants will be enrolled, randomized and treated. Enrolled participants will receive one, split-face Ulthera® treatment on the face and neck using a Ulthera System standard transducer on one side of the face and a…
- Trial name
- NCT02416076
- Testing
- Ulthera Treatment at EL2, Ulthera Treatment at EL4
- Where
- 3 sites in United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Ulthera, Inc
Facioscapulohumeral Muscular Dystrophy, Facioscapulohumeral Muscular Dystrophy 1
Ultrasound Detection of Early Facial Muscle Changes in FSHD: Thickness and Echo Intensity Findings
Facioscapulohumeral muscular dystrophy (FSHD) is characterized by early and significant involvement of facial muscles; however, objective imaging data focusing on facial muscles are limited.
- Conditions
- Facioscapulohumeral Muscular Dystrophy, Facioscapulohumeral Muscular Dystrophy 1, Neuromuscular Disease
- Trial name
- FACIAL-FSHD (NCT07331025)
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Koç University
Wrinkle
Study to Evaluate the Safety and Efficacy of the Cytrellis Micro-Coring Device for the Treatment of Moderate to Severe Facial Wrinkles
Study evaluating the efficacy of a micro coring device for the treatment of moderate to severe check wrinkles
- Trial name
- NCT03793348
- Testing
- MCD
- Where
- 6 sites in United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Cytrellis Biosystems, Inc.
Fine Lines, Wrinkles
A Clinical Study Evaluating the Efficacy and Tolerability of a Topical Facial Treatment For Facial Rejuvenation
This single-center clinical trial was conducted to evaluate the efficacy and tolerability of a topical facial treatment when applied by a license esthetician in clinic in a series of 3 sessions with 1 month intervals, in…
- Conditions
- Fine Lines, Wrinkles, Laxity; Skin
- Trial name
- NCT06629792
- Testing
- Gentle Cleanser, Facial Moisturizer, sunscreen SPF 30
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Photoaging, Wrinkle
Evaluating Procedure Pairing of a Post-Procedure Cream Versus a Comparator in Patients Treated With Fractional Ablative CO2 Laser for Facial Rejuvenation
This randomized, single-center, double-blinded, split-face, controlled clinical trial was conducted to investigate the tolerability, safety, and efficacy of a post-procedure cream when used immediately after fractional ablative…
- Conditions
- Photoaging, Wrinkle, Skin Laxity
- Trial name
- NCT06366503
- Testing
- Fractional Ablative CO2 Laser, Facial Cleanser, Facial Moisturizer
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Maxillofacial Deformity, Maxillofacial Abnormalities
a Comparative Analysis of Subspinal and Conventional Le Fort I Osteotomy on Nasolabial Soft Tissues
Following surgical operations, patients have aesthetic expectations as well as functional ones. To minimize undesirable aesthetic results after surgery and to increase the effectiveness of the surgery, the surgical method used…
- Conditions
- Maxillofacial Deformity, Maxillofacial Abnormalities, Maxillo-facial Surgery
- Trial name
- NCT07549659
- Testing
- conventional le fort I osteotomy type, subspinal le fort I osteotomy type
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Gilles de la Tourette's Syndrome
Facial Expression Recognition of Emotion and Categorization of Emotional Words in Gilles de la Tourette's Syndrome
Gilles de la Tourette's syndrome is a childhood onset inherited neuropsychiatric disorder characterised by the presence of both multiple motor tics and one or more vocal tics (noises), with psychiatric and/or behaviour disorders…
- Trial name
- NCT00664300
- Testing
- Facial expression recognition of emotion
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Facial Injuries and Disorders
PRP Administration in the Nasojugal Folds
The purpose of the study is to determine the efficacy of platelet-rich plasma (PRP) as a cosmetic facial injectable filler to treat tear troughs deformities secondary to volume loss and skin laxity in the infra-orbital region.
- Trial name
- PRP (NCT03255681)
- Testing
- PRP injections into nasojugal folds
- Volunteers
- healthy volunteers welcome
- Sponsor
- David Grant U.S. Air Force Medical Center
Cleft Lip, Cleft Lip and Palate
Assessing the Results of Lip Surgery in Patients With Cleft Lip and Palate
The purpose of this study is to determine whether secondary (revision) surgery to the lip in patients with cleft lip and palate is effective in improving lip function and appearance.
- Trial name
- NCT00070811
- Testing
- Lip revision surgery
- Where
- United States
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Skin Laxity
SofWave Treatment to Lift Lax Tissue in the Submental and Neck Zones and to Lift the Eyebrow
Open-label, non-randomized, prospective, multi-center, self-controlled clinical study with masked evaluation.
- Trial name
- NCT04969380
- Testing
- Sofwave
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sofwave Medical LTD
Cleft Lip and Palate
Slow Expansion and Protraction in Cleft Lip and Palate Patients
Evaluate the treatment outcome of slow maxillary expansion protocol on patients with cleft lip and palate, using a differential opening expander and face mask which will be measured and recorded by cone beam computed tomography…
- Trial name
- NCT04997083
- Testing
- Maxillary Expander with Differential Opening (EDO), Petit face mask
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Faculty of Dental Medicine for Girls
Dentofacial Deformities
Effects of Oral Melatonin on Neurosensory Recovery Following Facial Osteotomies
Orthognathic surgery is commonly performed for the treatment of dentofacial deformities. Yet, one of the most prevalent and long-term complication encountered is neurosensory disturbance thus impairing sensation to parts of the…
- Trial name
- NCT02889432
- Testing
- Oral Melatonin 10mg
- Where
- Hong Kong
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Skin Laxity, Facial Aging
RESTRUCTURING THE MANDIBULAR ANGLE IN FACIAL AGING: A NOVEL TECNIQUE USING POLY-L-LACTIC ACID
Skin laxity is a common complaint among patients seeking aesthetic dermatological interventions, affecting the facial contour, especially in the mandibular angle, due to bone aging and the loss of tissue support in the lower…
- Trial name
- NCT06948045
- Testing
- PLLA application to the mandibular angle
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Doris Hexsel