Clinical trials: Facial Pain, open to volunteers
Orofacial Pain
Safety and Efficacy of Lidocaine Versus Ketamine Infusion for Resistant Orofacial Pain
A prospective, randomized, double-blind clinical trial comparing the safety and efficacy of intravenous lidocaine, ketamine, and their combination as treatment options for patients suffering from treatment-resistant orofacial…
- Trial name
- NCT07250867
- Testing
- Lidocaine Intravenous Infusion, Ketamine intravenous infusion, Combined lidocaine and ketamine intravenous infusion
- Volunteers
- 105 people
- Sponsor
- Assiut University
Aneurysms, Arteriovenous Malformations
Neurosurgical Outcome Network
The evaluation of neurosurgical outcomes varies from center to center, and the predictive factors that determine these outcomes are not fully known or shared.
- Conditions
- Aneurysms, Arteriovenous Malformations, Cavernomas, Skull Base Tumors
- Trial name
- NEON (NCT06724029)
- Where
- 27 sites in Italy
- Volunteers
- 4,500 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Third Molar Surgery
Intraosseous Versus Submucosal Dexamethsone Injection in Third Molar Surgery
The goal of this clinical trial is to learn if intraosseous dexamethasone injection is better for pain and swelling postop 3rd molar surgery than submucosal dexamethasone injection.
- Trial name
- NCT06720051
- Testing
- Intraosseous dexamethasone injection after 3rd molar surgery, Submucosal dexamethasone injection after 3rd molar surgery
- Where
- Pakistan
- Volunteers
- 76 people
- Sponsor
- Services Institute of Medical Sciences, Pakistan
Pain, Postoperative, Pain, Chronic
fMRI and IVCM Cornea Microscopy of CXL in Keratoconus
Evaluation of neuroplasticity of pain pathways and corneal afferent nerve regeneration following corneal crosslinking (CXL) in keratoconus patients using fMRI and corneal In Vivo Confocal Microscopy (IVCM).
- Conditions
- Pain, Postoperative, Pain, Chronic, Pain, Acute, Surgical Injury
- Trial name
- NCT04439552
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Trigeminal Neuralgia
Intravenous Lacosamide for the Treatment of Acute Pain in Trigeminal Neuralgia
This prospective observational study evaluates the effectiveness and safety of intravenous lacosamide as a rescue treatment for acute pain in patients presenting to the emergency department with trigeminal neuralgia
- Trial name
- NCT06851910
- Testing
- Lacosamide
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Hospital Universitari de Bellvitge
Orofacial Pain, Sleep Bruxism
Orofacial Pain and Oral Health-Related Quality of Life in Musicians in German Amateur Orchestras
This cross-sectional online survey investigates the prevalence of orofacial pain, sleep-related problems, and oral health-related quality of life (OHRQoL) among adult musicians who play in German amateur orchestras.
- Conditions
- Orofacial Pain, Sleep Bruxism, Oral Health Related Quality of Life (OHRQoL)
- Trial name
- OSQ-MUS (NCT07714837)
- Testing
- Questionaire
- Where
- Germany
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University Medical Center Goettingen
Irreversible Pulpitis (toothache)
Garlic Oil As Root Filling Material in Primary Molars
The goal of this study is to test garlic oil mixed with zinc oxide as a potential root canal filling material of primary molars in children aged from four to eight years.
- Trial name
- NCT06755502
- Testing
- Garlic oil, Calcium Hydroxide, Iodoform, paste
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Analgesia, Emergencies
Nebulized Fentanyl in Healthy Volunteers
Pain constitutes the predominant motive prompting individuals to seek emergency medical attention, accounting for 80% of admissions to emergency departments.
- Trial name
- AEROfen (NCT06281951)
- Testing
- Fentanyl - Inhalation by facial nebulization, Fentanyl - Nebulisation
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Myofacial Pain Syndrome, Chronic Neck Pain
Focused Versus Multi-Target Trigger Point Injection for Chronic Myofascial Neck Pain
Myofascial neck pain may involve several active trigger points in the neck and shoulder muscles. In clinical practice, it is not clear whether treating only the main trigger point that best reproduces the patient's pain is…
- Trial name
- NCT07876739
- Testing
- Lidocaine 1% Trigger Point Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Mardin Artuklu University
Hemophilia, Chronic Pain
Multimodal Telerehabilitation Versus Face-to-Face Care for Adults With Hemophilia and Chronic Pain
Hemophilia is an inherited bleeding disorder that is commonly associated with chronic joint pain, reduced physical function, and decreased quality of life.
- Trial name
- HEMO-TELE (NCT07682519)
- Testing
- other, Exercise
- Where
- Chile
- Volunteers
- 24 people
- Sponsor
- University of Chile
Psychosomatic Symptoms, Temporomandibular Disorder (TMD)
Psychosomatic Symptoms in Patients With Myofascial Pain and Temporomandibular Joint Dysfunction
Temporomandibular joint disorder poses an intricate etiology. Biomechanical, neuromuscular and psychosocial factors may contribute to the disorder among which psychological and psychosocial disturbances have shown strong direct…
- Trial name
- Psychosomatic (NCT07385781)
- Testing
- Casr
- Where
- Pakistan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Bahria University
Dental Pain
A Combination of Ibuprofen With Curcumin Covered With Liquorice Root Supplementation in the Management of Postoperative Dental Pain in Adults
Dental pain, a common issue in stomatology, requires a multifaceted treatment approach. This study explores the efficacy of combining Ibuprofen with curcumin and liquorice root supplements for managing postoperative dental pain.
- Trial name
- ICLID (NCT06269406)
- Testing
- ibuprofen 400 mg in combination with Curcumin covered with liquorice root 100 mg, ibuprofen 200 mg in combination with Curcumin covered with liquorice root 100 mg
- Where
- Russia
- Volunteers
- 264 people
- Sponsor
- S.LAB (SOLOWAYS)
Cancer-related Pain, Pain Assessment
Developing a Multimodal Cancer Pain Database to Support AI-Based Automatic Pain Assessment
The goal of this observational study is to collect short video and sound recordings of people with cancer to create a secure database that can be used in future research to develop an artificial intelligence (AI) tool for pain…
- Conditions
- Cancer-related Pain, Pain Assessment, Artificial Intelligence (AI), Oncology
- Trial name
- SENSAI-DBD (NCT07262632)
- Testing
- Audiovisual and questionnaire-based data collection (once), Audiovisual and questionnaire-based data collection (consecutive)
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- Dr. Mark Mulder
Dental Anxiety, Dental Pain
Effect of Play Dough, Slime, and Plush Toys on Dental Anxiety and Pain in Children During Dental Treatment
This study aims to evaluate the effectiveness of tactile distraction materials, including play dough, slime, and plush toys, on dental anxiety, pain perception, and physiological stress responses in children undergoing dental…
- Conditions
- Dental Anxiety, Dental Pain, Behavioral Management
- Trial name
- PLAY-DENT (NCT07445594)
- Testing
- Play Dough Distraction, Slime Distraction, Plush Toy Distraction
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Afyonkarahisar Health Sciences University
Chronic Primary Orofacial Pain (CPOP), Persistent Idiopathic Facial Pain (PIFP)
An Innovative Cognitive-Behavioral Treatment For Chronic Orofacial Pain
Use these resources to provide understandable information about this study to patients, families, and health care providers: The present randomized clinical trial (RCT), conducted at the IRCCS Carlo Besta Neurological Institute…
- Trial name
- FACE-PRT (NCT07123233)
- Testing
- Pain Reprocessing Therapy, Usual Therapy
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Amyotrophic Lateral Sclerosis (ALS), Primary Lateral Sclerosis (PLS)
Investigating the Impact of Electrical Stimulation on Facial Pain, Jaw Movement and Oral Health in People With Motor Neuron Disease.
The goal of this clinical trial is to evaluate the impact of non-invasive electrical stimulation, when placed on the facial muscles can reduce facial pain and improve jaw mobility, and chewing in individuals with Amyotrophic…
- Conditions
- Amyotrophic Lateral Sclerosis (ALS), Primary Lateral Sclerosis (PLS), Motor Neuron Disease, Amyotrophic Lateral Sclerosis
- Trial name
- MND (NCT07187388)
- Testing
- Transcutaneous Electrical Nerve Stimulation to reduce facial pain and improve jaw range of motion in ALS and PLS
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Nova Southeastern University
Ankyloglossia, Tongue-tie
Healing Efficacy of Diode Laser in Lingual Frenectomy
This study aims to compare the wound healing efficacy and postoperative experiences between the 940 nm diode laser technique and the traditional electrosurgery method for treating ankyloglossia (tongue-tie) in children aged 3 to…
- Trial name
- NCT07557875
- Testing
- Lingual Frenectomy using 940nm Diode Laser, Lingual Frenectomy using High-frequency Electrosurgery
- Where
- 2 sites in Vietnam
- Volunteers
- 53 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Chronic Pain, Cancer Pain
Refining mUltiple Artificial intelliGence strateGies for Automatic Pain Assessment Investigations: RUGGI Study
This single-center, non-profit, observational-interventional study aims to develop artificial intelligence (AI) models for the automatic assessment of chronic pain (APA - Automatic Pain Assessment).
- Conditions
- Chronic Pain, Cancer Pain, Neuropathic Pain, Pain Assessment
- Trial name
- RUGGI (NCT07038434)
- Testing
- Multimodal AI-Based Pain Assessment
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Valentina Cerrone
Temporomandibular Disorders (TMDs)
Hard Splint Vs Conservative Therapy for TMJ Pain Management
The purpose of this study is to compare the efficacy of a hard occlusal splint versus conservative therapy (using topical Ibuprofen gel and counseling) in the management of patients with temporomandibular (TMJ) joint disorders.
- Trial name
- NCT07573137
- Testing
- Hard occlusal splint, Counseling and Habit Modification, Topical Ibuprofen gel
- Volunteers
- 60 people
- Sponsor
- Khyber College of dentistry
Pulp Disease, Dental, Pulpitis
Predicting Vital Pulp Treatment Outcomes in Symptomatic Pulpits Using Metabolic Biomarker
This prospective controlled clinical trial investigates whether metabolic biomarkers measured in pulpal blood at the time of carious pulp exposure can predict the 12-month outcomes of vital pulp treatment in symptomatic permanent…
- Conditions
- Pulp Disease, Dental, Pulpitis, Reversible Pulpitis, Irreversible Pulpitis (Toothache)
- Trial name
- NCT07452614
- Testing
- vital pulp treatment
- Where
- Iraq
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Abeer Ghalib Abdul-khaliq