Clinical trials: Facial Rhytides
Healthy
A Study to Assess Effect of Two Facial Sunscreens in Improving Wrinkles, Fine Lines and Melasma in Adult Participants
The purpose of this study is to evaluate the topical safety (tolerability/acceptability) and efficacy of two facial sunscreen in improving wrinkles, fine lines and melasma after 84 +/- 2 days of use under normal conditions on the…
- Trial name
- NCT05864417
- Testing
- Sunscreen Color tone 2.0, Sunscreen Color tone 3.0
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Skin Ageing, Facial Wrinkles - Rough Texture - Hyperpigmentation
Clinical Effects of Two Oral Bioactive Collagen Peptides On Skin Properties and Aging Hallmarks
This randomized, controlled clinical trial evaluated whether daily oral intake of a collagen peptides supplement improved age-associated skin beauty parameters in healthy women with visible facial wrinkles.
- Conditions
- Skin Ageing, Facial Wrinkles - Rough Texture - Hyperpigmentation, Skin Hydration in Healthy Volunteers
- Trial name
- NCT07302789
- Testing
- Dietary Supplement: Collagen Peptides Supplement, Dietary Supplement: Competitor's Collagen Supplement
- Where
- Spain
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Bionos Biotech S.L.
Nasolabial Fold
Clinical Trial to Evaluate the Efficacy and Safety in Nasolabial Fold After Rhytidectomy Using Non-absorbable Mesh
The aim of this study is to evaluate the efficacy and safety of the investigational device, RPM,non-absorbable polypropylene mesh made by D Med, in correction of Nasolabial fold.
- Trial name
- NCT01775293
- Testing
- Non-absorbable polypropylene mesh
- Where
- South Korea
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Wrinkle
A Comparative Analysis of Two Hyaluronic Acid Fillers for Nasolabial Fold Correction
This is a randomized, split-face, subject-blinded, comparative study. Subjects will receive initial treatment with Defyne on one of the NLFs and with RHA3 on the other based on the pre-determined randomization.
- Trial name
- NCT06351293
- Testing
- Defyne Treatment in Nasolabial Fold, RHA3 Treatment in Nasolabial Fold
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Facial Wrinkles - Rough Texture - Hyperpigmentation
Evaluation of Microinjected Amnion-derived Collagen by Dermapen in the Smoothing of Skin Wrinkles
The aim of this work was to assess the efficacy of irradiated amniotic collagen matrix in comparison with platelet rich plasma in facial rejuvenation.The present study included 20 patients with facial wrinkles divided into 2…
- Trial name
- NCT06054646
- Testing
- Amnion collagen, Platelet-rich plasma
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Egyptian Atomic Energy Authority
Facial Wrinkles
Safety and Effectiveness of Aquamid as Compared to Restylane for the Aesthetic Treatment of Nasolabial Folds
The purpose of this study is to compare the effectiveness of Aquamid and Restylane in aesthetically enhancing nasolabial folds 6 months after treatment and to evaluate the safety of Aquamid through 12 months after treatment.
- Trial name
- NCT00407914
- Testing
- Aquamid, Restylane
- Where
- United States
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- Contura
Temporary Correction of Wrinkles
Clinical Study to Evaluate the Correction of Facial Wrinkles and Folds and Safety of YVOIRE Volume Versus Perlane in Nasolabial Fold Injection
This study was purposed to evaluate the non-inferiority of YVOIRE volume, a hyaluronic acid product, in terms of correction of wrinkles and safety in nasolabial fold deep-dermal injection, compared to Perlane, the control…
- Trial name
- NCT03738007
- Testing
- HA IDF II, Perlane
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- LG Life Sciences
Wrinkles, Acne Scars
Epidermal Delivery of Ani-Aging Ingredients
To assess the safety and efficacy of an ablative fractional, 2940-nm laser combined with the US Impact and cosmetic -formulations for improving the appearance of wrinkles, acne scars and pigmented skin.
- Conditions
- Wrinkles, Acne Scars, Pigmentation
- Trial name
- NCT01847066
- Testing
- Erbium 2940 plus cosmetics plus Impact, Erbium 2940 plus cosmetics
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Alma Lasers Inc.
Wrinkles
Post-market Clinical Follow-up (PMCF) Study of Safety and Performance of 502-01 AnGelHA 2
Post-market clinical follow-up (PMCF) investigation to evaluate the performance and safety of AnGelHA 2 filler for the correction of moderate to severe wrinkles and folds and facial contour remodeling, in a routine clinical…
- Trial name
- NCT07495865
- Where
- Israel
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Glyance
Facial Wrinkles, Skin Aging
Anti-Wrinkle Efficacy of a Syringic Acid-Containing Emulsion
This randomized, double-blind, split-face controlled study was conducted to evaluate the anti-wrinkle efficacy and safety of a Syringic acid-containing emulsion in healthy female subjects.
- Trial name
- NCT07850817
- Testing
- Synox-containing Emulsion, Control Emulsion
- Where
- South Korea
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- BioSpectrum Inc
Skin Aging
Clinical Trial to Assess Efficacy, Safety and Tolerability of Botulinum Toxin A (Xeomin®) in Treatment of Expression Wrinkles in the Upper Third of the Face
The purpose of this study is to determinate whether Xeomin® (Botulinum toxin Type A) is safe, effective and tolerable in woman aged 30 to 50 years old for treatment of mild, moderate or severe expression lines (wrinkles) in the…
- Trial name
- XEO-001/07 (NCT00986570)
- Testing
- Botulinum Toxin A
- Where
- Brazil
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Biolab Sanus Farmaceutica
Peri-orbital Rhytides
Ablative Fractional Lasers to Treat Peri-orbital Rhytides
Ablative fractional lasers were introduced for treating facial rhytides in an attempt to achieve results comparable to traditional ablative resurfacing but with fewer side effects.
- Trial name
- NCT00990431
- Testing
- Fractional carbon dioxide laser treatment, Fractional erbium:YAG laser treatment
- Where
- Germany
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Laserklinik Karlsruhe
Aging, Botulinum Toxin
The Impact of Age on Botulinum Toxin Potency in Facial Rhytides Treatment
Botulinum toxin is approved by the FDA for the treatment of facial wrinkles. Patients are usually older than 45 years and their main demand is to treat pre-existing facial wrinkles.
- Conditions
- Aging, Botulinum Toxin, Facial Wrinkles
- Trial name
- NCT03836638
- Testing
- 30 Units of botulinum toxin, 50 Units of botulinum toxin
- Where
- Lebanon
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- St Joseph University, Beirut, Lebanon
Facial Wrinkles, Anti-Aging
Safety and Efficacy Evaluation of the Monopolar Radiofrequency Device for the Improvement of Facial Wrinkles
The goal of this clinical trial is to evaluate the safety and efficacy of the monopolar radiofrequency therapy device developed by CLASSYS Inc. for improving facial and periorbital wrinkles.
- Conditions
- Facial Wrinkles, Anti-Aging, Wrinkles and Rhytides, Wrinkles Such as Nasolabial Folds
- Trial name
- NCT06657365
- Testing
- Radiofrequency (RF) Treatment with Volnewmer, Radiofrequency (RF) Treatment with Thermage CPT
- Where
- China
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- CLASSYS Inc.
Lateral Canthal Lines
Safety and Efficacy Study of RT001 to Treat Moderate to Severe Lateral Canthal Lines
The purpose of this study is to evaluate the safety and efficacy of RT001 to treat moderate to severe lateral canthal lines in adults and duration of effect.
- Trial name
- NCT00907387
- Testing
- RT001
- Where
- 9 sites in United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Revance Therapeutics, Inc.
Skin Aging, Facial Wrinkles
Study of the Subdermal Implant "Ultracol"
Study of the effectiveness of the medical device "Intradermal implant, sterile ULTRACOL based on polydioxanone (ULTRA V Co., Ltd., Korea) in the correction of skin contour defects.
- Conditions
- Skin Aging, Facial Wrinkles, Senile Skin Atrophy, Lipodystrophy
- Trial name
- NCT07617350
- Testing
- Administration of the prepared solution - 1 time Post injection observation - 30, 60, 160 days from the date of the first injection.
- Where
- Russia
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Estelab Clinic
Facial Wrinkles
Evaluation of Safety and Efficacy of TriPollar Device for Treatment of Wrinkles
The TriPollar is intended for non invasive treatment of facial wrinkles and rhytides. This study was designed in order to evaluate the safety and efficacy of the TriPollar.
- Trial name
- NCT01858415
- Testing
- TriPollar
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Pollogen
Wrinkles
Study of BOTOX and JUVEDERM for Treatment of Moderate to Severe Facial Wrinkles and Folds
The purpose of this study is to see how well Juvederm Ultra XC or Juvederm Ultra Plus XC, and BOTOX Cosmetic, work compared to each other and when used together for the cosmetic treatment of age-associated wrinkles and folds of…
- Trial name
- JUVE_BTX (NCT01269801)
- Testing
- onabotulinumtoxinA, JUVÉDERM
- Where
- 3 sites in United States, Canada
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- AboutSkin Dermatology and DermSurgery, PC
Facial Aging, Skin Laxity
Quantified Evaluation of Noninvasive System Delivering Microwave Energy for Unwanted Fat Reduction and Skin Tightening in Asians.
The goal of this observational study is to evaluate the effectiveness and safety of microwave-assisted heating technology in facial fat reduction and skin tightening in Asians. The main questions it aims to answer are: 1.
- Conditions
- Facial Aging, Skin Laxity, Cheek Wrinkles
- Trial name
- NCT06925074
- Where
- Taiwan
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Chang Chang Cheng
Facial Skin Aging and Wrinkle Severity
Antioxidant Nutrition and Facial Exercise for Skin Aging
This randomized controlled trial will evaluate the effects of a 12-week combined antioxidant-rich nutrition and facial exercise program on skin quality and wrinkle severity in middle-aged women.
- Trial name
- NCT07792447
- Testing
- Combined Antioxidant Nutrition and Facial Exercise Program
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Zakho