Clinical trials: Facial Skin Aging
Skin Aging
A Clinical Study to Evaluate the Efficacy and Satisfaction of Ultrasound Therapy Combined With SkinCeuticals A.G.E for Improving Facial Aging
A Prospective, Single-center, Single-blind, Randomized split-face, controlled trial will be conducted. The goal of this clinical trial is to evaluate the efficacy and satisfaction of ultrasound therapy combined with SkinCeuticals…
- Trial name
- NCT05748470
- Testing
- SkinCeuticals A.G.E, standard cream
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Yes Skin Medical Group
Facial Aging, Skin Aging
Hyaluronic Acid Crosslinking Clinical Study
This prospective observational case series aims to evaluate the clinical efficacy, safety, and patient satisfaction associated with hyaluronic acid dermal fillers with different degrees of divinyl sulfone (DVS) crosslinking.
- Conditions
- Facial Aging, Skin Aging, Facial Volume Loss, Facial Rhytides
- Trial name
- HACS (NCT07744464)
- Testing
- Hyaluronic Acid Dermal Fillers
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Antony de Paula Barbosa
Facial Skin, Motion Capture
Research on the Evolution, Geometry, and Alterations of the Periorbital Region Based on Age and Deformations
The periorbital region of the face is a critical area affected by aging. Motion Capture (MoCap) allows the precise measurement of the mechanical properties of skin in this region.
- Conditions
- Facial Skin, Motion Capture, Aging, Periorbital Region
- Trial name
- REGARD (NCT07080320)
- Testing
- MoCap
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Skin Aging of Face and Hands, Facial Wrinkles - Rough Texture - Hyperpigmentation
DMAE Oleate for Facial Skin Firmness and Fine Lines in Healthy Adults
This single-arm, cosmetic study will evaluate the efficacy of topical DMAE Oleate on facial skin firmness and lines/wrinkles in healthy adults.
- Conditions
- Skin Aging of Face and Hands, Facial Wrinkles - Rough Texture - Hyperpigmentation, Skin Laxity
- Trial name
- NCT07255560
- Testing
- Topical DMAE Oleate
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bionos Biotech S.L.
Skin Aging
Evaluation of the Anti-aging Efficacy of One Face Care Cosmetic Product
The purpose of this study is to evaluate the anti-wrinkle efficacy and effect on skin epigenetic and on mitochondrial morphology of a facial cosmetic product compared to a placebo
- Trial name
- SkinBioAge (NCT06619457)
- Testing
- Mitopure (Urolithin A) Cream
- Where
- Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Amazentis SA
Skin Aging
Autologous Fibroblast Grafts in Facial Skin Regeneration
The purpose of this study is to evaluate the presence of skin changes after grafting of autologous fibroblasts by means of biophysical, histological, immunohistological, gene expression, glycosaminoglycan, and sensitivity…
- Trial name
- NCT01490554
- Testing
- autologous fibroblasts grafts
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Skin Aging
Evaluation of the Safety and Efficacy of Profhilo® Structura
Profhilo® Structura is composed of a buffered saline solution of high molecular weight (H-HA) and low molecular weight (L-HA) hyaluronic acid.
- Trial name
- NCT06719154
- Testing
- Profhilo Structura
- Where
- 3 sites in France, Poland
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- IBSA Farmaceutici Italia Srl
Healthy Adult Females
Clinical Study to Evaluate the Anti-aging Efficacy and Skin Radiance-enhancing Effect of Dermial®.
The present clinical study has been designed to evaluate the efficacy and safety of Dermial® at a daily dose of 60 mg on skin brightness, hydration, luminosity and other signs of facial skin aging in healthy women aged 35 to 65…
- Trial name
- Dermiglow (NCT07790237)
- Testing
- DERMIAL
- Where
- Spain
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Bioiberica
Skin Aging, Facial Aging
Objective Evaluation of Intradermal MSC-Derived Exosome Therapy on Facial Skin Quality
This study aims to evaluate the potential effects of mesenchymal stem cell-derived suspended exosome therapy on facial skin quality using objective imaging analysis.
- Conditions
- Skin Aging, Facial Aging, Skin Quality
- Trial name
- NCT07466953
- Testing
- Mesenchymal Stem Cell-Derived Exosome
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mert Ersan
Skin Aging
A Comparative Split-Face Study of the Effects of a Retinol Alternative Cream on Improving Facial Skin Aging
This study will evaluate the efficacy of the DIME TBT Cream in improving the appearance and hydration of aged skin in comparison to a retinol cream. This study will last for 60 days.
- Trial name
- NCT06125912
- Testing
- Dime Beauty TBT Cream, Positive Control
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Dime Beauty Co.
Skin Aging, Skin Wrinkling
Evaluation of the Safety and Performance Characteristics of Mesofiller Mesotox for the Correction of Wrinkles and Rehydration of the Face.
The investigation is a single-centre, interventional, prospective, non-randomized, open-label, uncontrolled, single-arm, un-blinded investigation for the evaluation of the safety and performance of the product mesofiller® mesotox…
- Trial name
- NCT06477432
- Testing
- mesofiller® mesotox
- Where
- Bulgaria
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Mesoestetic Pharma Group S.L.
Skin Aging
Poly-L-lactic Acid for Skin Quality
Anecdotal evidence suggests that patients' skin quality may improve as a result of poly-L-lactic acid injection. While this is not the primary goal of such treatments it is often seen and described as so called "Sculptra glow".
- Trial name
- NCT02003833
- Testing
- Poly-L-lactic acid
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sadick Research Group
Healthy
Efficacy and Tolerance Evaluation of a Topical "Revitalizing" Face Day Cream
Aim of the study was to evaluate clinically and by non-invasive instrumental evaluations the "revitalizing" activity of a face cream applied twice a day, morning and evening, for an uninterrupted period of 8 weeks, by healthy…
- Trial name
- NCT02230397
- Testing
- plantaricin a (active product)
- Where
- Italy
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Derming SRL
Skin Health, Skin Aging of Face and Hands
The Effect of Nutritional Supplementation on Actinic Purpura: A Pilot Study
Purpura is a macule or papule of blood in the skin. It is mostly seen in mature skin that is often prone to significant bruising.
- Conditions
- Skin Health, Skin Aging of Face and Hands, Healthy, Ecchymosis
- Trial name
- NCT06840574
- Testing
- Cyruta Plus: A Whole-Food Based Vitamin C supplement containing organic buckwheat (aerial parts) juice powder, organic buckwheat flour, bovine adrenal Cytosol™ extract, oat flour, honey, ascorbic acid, Low Dose Vitamin C, High Dose Vitamin C
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Standard Process Inc.
Aging
Superficial MFU-V and Diluted Calcium Hydroxyapatite for the Improvement of Lower Face Skin Quality and Wrinkles
This single-center pilot study evaluated whether one treatment session combining superficial microfocused ultrasound with visualization (MFU-V, Ultherapy, 1.5 mm transducer) and diluted calcium hydroxylapatite (CaHA, Radiesse…
- Trial name
- NCT05469516
- Testing
- Ulthera System [Ulthera, Inc.], Merz Radiesse Injectable Implant
- Where
- Singapore
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Cutis Medical Laser Clinics Pte Ltd
Skin Aging, Photoaging
Effects of Stabilized Retinaldehyde on Aging Skin: A Split-Face Study
The goal of this clinical trial is to learn if retinaldehyde cream improves the appearance of aging skin in women aged 30 to 60 years.
- Trial name
- NCT07510165
- Testing
- Stabilized retinaldehyde 0.1%, Stabilized retinaldehyde 0.05%
- Where
- Poland
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Medical University of Silesia
Seborrheic Keratosis (SK), Oxidative Stress
Relationship Between Serum Xanthine Oxidase Levels and Seborrheic Keratosis
This observational study aims to examine the relationship between serum xanthine oxidase (XO) levels and seborrheic keratosis (SK), a common benign skin tumor, especially in middle-aged and older adults.
- Conditions
- Seborrheic Keratosis (SK), Oxidative Stress, Skin Aging
- Trial name
- SK-XO (NCT07095348)
- Testing
- Serum Xanthine Oxidase Level Assessment
- Where
- Indonesia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sri Nauli Dewi Lubis
Skin Aging, Skin Hydration
Skin Hydration and Facial Aging in Women Aged 30-60: An Observational Correlational Study Using Bioimpedance Analysis
This study investigates whether skin hydration levels are related to how old the skin looks. Thirty women aged 30 to 60 years will attend a single visit at a licensed esthetic practice in Florida.
- Conditions
- Skin Aging, Skin Hydration, Facial Aging, Transepidermal Water Loss
- Trial name
- SHFA-30-60 (NCT07564869)
- Testing
- BT-Analyze Bioimpedance Measurement
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- IAS Skin Care
Facial Aging
Evaluating Facial Skin Quality Changes Post-Lipofilling
The goal of this prospective observational study is to evaluate changes in facial skin quality and identify predictive biological markers in donor adipose tissue in healthy women undergoing autologous facial fat transfer.
- Trial name
- NCT07737639
- Where
- France
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- L'Oreal
Photoaging, Skin Aging
AI-Personalized Skincare Regimen for Facial Photoaging in Women
The goal of this clinical study was to learn whether a skincare regimen personalized by an artificial intelligence (AI) skin-analysis tool improves signs of facial skin aging in women aged 35 to 65 with mild-to-moderate facial…
- Trial name
- NCT07879833
- Testing
- AI-personalized skin longevity regimen
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- MDalgorithms Inc.