Clinical trials: Faeces
Bipolar Disorder, Major Depressive Disorder
The Gut Microbiota of Bipolar and Depression
Background: The gut microbiome is emerging as an important factor in regulating mental health yet it remains unclear what the target should be for psychiatric treatment.
- Trial name
- NCT03062332
- Testing
- Faecal genome
- Where
- China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Colon Adenoma
Usefulness of Calprotectin for Colon Adenoma Screening
The fecal calprotectin assay is used widely for inflammatory bowel disease diagnosis and the assessment of the disease activity.
- Trial name
- NCT01719198
- Where
- South Korea
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Konkuk University Medical Center
Dementia With Lewy Bodies, Alzheimer Disease
DIagnostic Biomarkers and Symptoms in Patients With Alzheimer's Disease and Lewy bodY Dementia
This a study to improve diagnosis of dementia with Lewy bodies with RT-QuIC in different biospecimens.
- Conditions
- Dementia With Lewy Bodies, Alzheimer Disease, Mild Cognitive Impairment
- Trial name
- DISPLAY (NCT05768425)
- Testing
- Real-time quaking-induced conversion (RT-QuIC), Cognitive test, Motor examination
- Where
- Denmark
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Danish Dementia Research Centre
Non-Alcoholic Fatty Liver Disease, Obesity
Effects of Dietary Fructose on Gut Microbiota and Fecal Metabolites in Obese Men and Postmenopausal Women: A Pilot Study
Non alcoholic fatty liver disease (NAFLD) is the most common cause of abnormal liver function tests in the U.S. (Browning, et al., 2004), ranging from steatosis to end-stage liver disease.
- Trial name
- NCT03339245
- Testing
- Fructose Solution (75 Grams), Glucose Solution (75 grams)
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Rockefeller University
CMV Colitis
Stool and Serum CMV-PCR in Diagnosing CMV Colitis
CMV viral load detected by real-time polymerase chain reaction (PCR) in either serum or stool may be beneficial in diagnosing CMV colitis, but the data is limited.
- Trial name
- NCT05522283
- Testing
- Stool and blood CMV PCR
- Where
- Thailand
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Healthy
SwissGut - The Healthy Swiss Microbiome
Objective: This study is designed to address the complex interplay between the gut microbiome, environmental factors, and inflammatory diseases, with a specific emphasis on serving as a healthy cohort for several related…
- Trial name
- SwissGut (NCT06191224)
- Where
- Switzerland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Benjamin Misselwitz
Attention-deficit/Hyperactivity Disorder
Washed Microbiota Transplantation for Attention-deficit/Hyperactivity Disorder
Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disorder characterized by inattention and hyperactivity-impulsivity.
- Trial name
- WMT for ADHD (NCT06376331)
- Testing
- washed microbiota transplantation
- Where
- 2 sites in China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Nanjing Medical University
Constipation
Impact of a Synbiotic Containing Fructo-oligosaccharides and Bifidobacteria in Middle-aged Adults
The aim of the study is to evaluate the impact of a synbiotic containing fructo-oligosaccharides (FOS) and Bifidobacteria (VES002 LMG P-28149) on intestinal transit in middle-aged subjects characterized by a low number of…
- Trial name
- NCT04283266
- Testing
- Synbiotic
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Vesale Pharmaceutica
Constipation, Gastrointestinal Dysfunction
Effect of Polydextrose on Fecal Bulk and Bowel Function in Mildly Constipated Subjects
Polydextrose (PDX) (8-30g/day) has been reported to increase faecal bulk and consistency, leading to easier stool passage in healthy subjects.
- Trial name
- NCT05309837
- Testing
- Polydextrose
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Tate & Lyle
Healthy Volunteer
Assess Gastrointestinal Blood Loss After Receiving Aspirin or Aspirin Plus Rivaroxaban in Healthy Adult Participants
The primary objective of the study is to determine whether aspirin alone or aspirin combined with various doses of rivaroxaban causes subclinical GI blood loss as determined by the HemoQuant assay.
- Trial name
- NCT05546957
- Testing
- Aspirin, rivaroxaban low dose, rivaroxaban high dose
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Regeneron Pharmaceuticals
Diabetes Mellitus, Type 2, Obesity
Fecal Microbiota Transplantation for Diabetes Mellitus Type II in Obese Patients
The incidence of obesity has dramatically increased during the last three decades, leading to a significant increase of obesity-related morbidity, including type 2 diabetes mellitus (T2DM) that is characterized by resistance of…
- Trial name
- NCT02346669
- Testing
- gastroscopy, Fecal Microbiota Transplantation, high fat low fiber diet
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Microbial Composition
Optimization of Collection Methods for Studies of the Human Microbiota
Background: The human microbiota is the bacteria and other microbes found in and on the human body. Scientists study the microbiota because it is related to many health conditions.
- Trial name
- NCT03731702
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Parkinson Disease
Effects of Resistant Starch on Bowel Habits, Fecal Short Chain Fatty Acids and Gut Microbiota in Parkinson Disease
The investigators will investigate the effects of an 8-week resistant starch (RS) supplementation (5 g twice a day) in patients with Parkinson Disease and matched controls on: 1.
- Trial name
- RESISTA-PD (NCT02784145)
- Testing
- Resistant starch, Recommendation with regard to nutrition
- Where
- Germany
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Universität des Saarlandes
Colorectal Cancer
Innovative Tools to Improve Colorectal Cancer Screening Rates in Manitoba
The primary purpose of the study is to investigate the efficacy and effectiveness of a community-based nurse managed telephone support line (Provincial Health Contact Center; PHCC) and Colorectal Cancer Information and Screening…
- Trial name
- NCT01026753
- Testing
- Refrigerator Magnet
- Where
- Canada
- Volunteers
- 2,395 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Microbial Colonization
Collection of Microbiome Samples of Healthy Western Donors for Fundamental and Functional Microbiome Research
Large numbers of micro-organisms (especially bacteria) live in and on human bodies and have a very important function for the health. These microorganisms are called 'the microbiota'.
- Trial name
- NCT06466707
- Testing
- Collection of microbiome samples
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Ghent
Recurrent C. Difficile Associated Diarrhea
Fresh, Frozen or Lyophilized Fecal Microbiota Transplantation for Multiple Recurrent C. Difficile Associated Diarrhea
The objective of the study is to investigate the efficacy of fresh, frozen or lyophilized fecal microbiota transplantation (FMT) via colonoscopy in patients with recurrent C. difficile associated diarrhea (RCDAD).
- Trial name
- NCT02318992
- Testing
- Fecal Microbiota
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Colorectal Cancer
Comparison of Fecal Ribonucleic Acid (RNA) Test With Fecal Occult Blood Test (FOBT) for Detecting Colorectal Cancer and Adenoma
Colorectal cancer (CRC) is the second common cause of death in the Western world, and is very increasing in Japan. Fecal occult blood test (FOBT) is used routinely for CRC screening, which has been shown to reduce the incidence…
- Trial name
- NCT00197405
- Where
- Japan
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Hamamatsu University
Digestibility
Effects of Time-restricted Eating on Nutrient Absorption in Healthy Adults
This 2-period, crossover, controlled-feeding trial will investigate the effects of early time-restricted eating (8am-2pm), compared to a control eating timeframe (8am-8pm), on energy and macronutrient digestibility, the thermic…
- Trial name
- NCT04877262
- Testing
- weight maintenance diet (WMD)
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Florida State University
Food Allergy in Infants
The Tolerance of Organic Formula Milk and Its Fecal Microbiome Characteristic in Infants
This interventional study aims to investigate the tolerance of organic formula milk on infants supplemented with organic formula milk.
- Trial name
- TOFeM (NCT05215080)
- Testing
- Organic Formula Milk
- Where
- Indonesia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hasanuddin University
Ulcerative Colitis
Impact of Fecal Microbiota Transplantation in Ulcerative Colitis
Ulcerative colitis (UC) is a chronic relapsing inflammatory bowel disease. UC pathogenesis remains poorly understood but involves an inappropriate immune response toward an unbalanced gut microbiota (called dysbiosis) in…
- Trial name
- REBALANCE-UC (NCT03483246)
- Testing
- Fecal Microbiota Transplantation (FMT)
- Where
- France
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris