Clinical trials: Familial Dementia
Dementia, Decision Aids
Decision Aid for Dementia Therapies
The purpose of this study is to develop a decision aid to support patients and families making decisions about medications for dementia.
- Trial name
- NCT06638632
- Testing
- Decision aid
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Dementia Caregiver
Dementia Family Caregiver Study
The proposed study will test a 3-month, community health worker (CHW) delivered home visit, culturally and language-appropriate intervention for ethnic and underserved dementia family caregivers of persons with dementia (PWD)…
- Trial name
- NCT04894006
- Testing
- Community Health Worker (CHW) Home Visit Intervention, Attention Control Group with WIoT Technology, Usual Care
- Where
- United States
- Volunteers
- 332 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Alzheimer's Disease, Dementia
iCare Stress Management e-Training for Dementia Family Caregivers
Photozig and Stanford University are creating a program to help cope with caregiving, alleviate related stress, and enhance quality of life for caregivers, with funding from the National Institute on Aging.
- Trial name
- iCare (NCT01378195)
- Testing
- CBT-based program for dementia caregivers, Educational/Resources program
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Photozig, Inc.
Undiagnosed Disease, Healthy Volunteer (Adult With Typically Developing Child)
Inherited Diseases, Caregiving, and Social Networks
Approximately 66 million informal caregivers care for someone who is ill, disabled, or aged. These caregivers experience significant distress associated with caregiving, which may be particularly salient in the context of…
- Conditions
- Undiagnosed Disease, Healthy Volunteer (Adult With Typically Developing Child), Inherited Neurodegenerative Disorders, Inherited Metabolic Disorders (Inborn Errors of Metabolism)
- Trial name
- NCT01498263
- Where
- 2 sites in United States
- Volunteers
- 682 people, healthy volunteers welcome
- Sponsor
- National Human Genome Research Institute (NHGRI)
Dementia, Alzheimer Disease
Learning Skills Together Family Caregiver Complex Intervention
Learning Skills Together (LST) is a 6-week psychoeducational intervention focused on complex care (nursing) tasks completed by family caregivers to persons living with Alzheimer's Disease and related dementias.
- Conditions
- Dementia, Alzheimer Disease, Caregiver Burden, Self Efficacy
- Trial name
- LST (NCT05846984)
- Testing
- Learning Skills Together Intervention, Caregiver Healthy Living Intervention
- Where
- United States
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Alzheimer Disease
Virtual Patient Behavioral Response Training for Family Caregivers
Our study is designed to help caregivers of someone with Alzheimer's Disease and related dementia to understand and deal with the difficult behaviors of a person with dementia.
- Trial name
- NCT04489303
- Testing
- Caring Response App, Traditional Educational/Resources Program
- Where
- United States
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Photozig, Inc.
Alzheimer Disease, Dementia
CONFIDENCE-AI Financial Education for Caregivers (CONFIDENCE-AI)
The intervention being tested, CONFIDENCE-AI is a refined version of the original CONFIDENCE intervention made to reduce psychological financial strain and improve management of out-of-pocket care costs while increasing caregiver…
- Conditions
- Alzheimer Disease, Dementia, Caregiver Burden, Financial Stress
- Trial name
- CONFIDENCE-AI (NCT06134180)
- Testing
- CONFIDENCE-AI
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Dementia, Cognitive Impairment
Functionally-tailored Oral Care Intervention for Community-dwelling Older Adults With Dementia and Their Caregivers
The specific aims of this study are: Aim 1. Develop a staged and modifiable dyadic oral care intervention to provide functionally-tailored oral care rehabilitation for community-dwelling persons with dementia (PWD) and need-based…
- Trial name
- NCT04238520
- Testing
- Functionally Tailored Oral Care Intervention, Control Intervention
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Xi Chen
Dementia, Alzheimer Disease
Care to Plan: a Tailored Resource for Family Members of Persons With Dementia
The present study will refine and conduct a preliminary efficacy evaluation of Care to Plan. Care to Plan is an online care planning tool that provides a succinct and clear overview of various types of dementia caregiver…
- Conditions
- Dementia, Alzheimer Disease, Memory Loss
- Trial name
- NCT03901456
- Testing
- Care to Plan, Usual Care
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Stress Disorders, Post-Traumatic, Depression
Resettled Refugee Families for Healing
The goal of this type I hybrid effectiveness-implementation trial is to test a family strengthening (FS) model delivered through multiple family groups (MFG) combined with a virtual peer mentoring program called TeenAge Health…
- Conditions
- Stress Disorders, Post-Traumatic, Depression, Antisocial Personality Disorder, Anxiety
- Trial name
- RRF4H (NCT06176638)
- Testing
- RRF4H Combination Intervention
- Where
- United States
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Amyotrophic Lateral Sclerosis (ALS), Familial Amyotrophic Lateral Sclerosis
Genetics of Familial and Sporadic ALS
We are collecting blood samples, clinical and family information from ALS (amyotrophic lateral sclerosis) patients and their families to identify causes of ALS and ALS/dementia.
- Conditions
- Amyotrophic Lateral Sclerosis (ALS), Familial Amyotrophic Lateral Sclerosis, ALS With Frontotemporal Dementia (ALS/FTD), Lou Gehrig's Disease
- Trial name
- ALS (NCT00821132)
- Testing
- Genetic study of ALS families
- Where
- United States
- Volunteers
- 13,521 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Dementia
Brief Behavioural Treatment for Insomnia in Dementia Carers
Background: between 50-74% of dementia carers report some sleep disturbance. However, relatively few studies have looked at psychological treatment for insomnia in this group.
- Trial name
- NCT02983032
- Testing
- BBTI
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- NHS Greater Glasgow and Clyde
Dementia, Dementia Alzheimers
Persons With Dementia and Their Extended Family Caregivers
Immediate family members shoulder the majority of care responsibilities for persons living with dementia. However, due to various societal changes, elder care responsibilities have expanded to extended family members, including…
- Conditions
- Dementia, Dementia Alzheimers, Neuro-Degenerative Disease, Dementia of Alzheimer Type
- Trial name
- CareEx (NCT04863859)
- Where
- United States
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Karen Roberto
Acceptance and Commitment Therapy, Caregiver Burden
Acceptance and Commitment Therapy (ACT) Tele-Counselling
A randomized 2-group controlled trial will be conducted to explore the potential effect and potential feasibility of a new Acceptance and Commitment Therapy (ACT) tele-counselling program to improve mental health services for…
- Conditions
- Acceptance and Commitment Therapy, Caregiver Burden, Digital Health, Technology
- Trial name
- NCT05385458
- Testing
- ACT Intervention, Usual Care
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of New Brunswick
Carers, Dementia
Family Interventions iN Dementia Mental Health Environments
Study Goal: Understand carers' needs when someone with dementia is in a mental health ward and develop strategies to support carers as partners in care.
- Trial name
- FIND ME (NCT06937541)
- Where
- United Kingdom
- Volunteers
- 343 people, healthy volunteers welcome
- Sponsor
- University of West London
Elder Mistreatment, Elder Abuse
Knowledge and Interpersonal Skills to Develop Enhanced Relationships (KINDER)
The Knowledge and Interpersonal Skills to Develop Enhanced Relationships (KINDER) intervention was developed to prevent psychological elder abuse (EA) and promote high-quality caregiving by lowering relationship strain and…
- Conditions
- Elder Mistreatment, Elder Abuse, Quality of Care, Dementia
- Trial name
- KINDER (NCT07216950)
- Testing
- Knowledge and Interpersonal Skills to Develop Enhanced Relationships, Healthy Living for the Caregiver
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Dementia
Pilot Evaluation of Technology-enhanced Horticultural Activities Among the People With Dementia and Their Family Caregivers
Horticultural therapy is one of the effective interventions for the person with dementia(PWD) which could increase their time engaging in leisure activities and decrease their time doing nothing.
- Trial name
- NCT05577975
- Testing
- The Aspara @ smart grower
- Where
- Hong Kong
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Alzheimers Disease, Dementia
A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation
The purpose of this research study is to test the study drug, referred to as remternetug, to determine its effectiveness for the study treatment of asymptomatic (at risk) Alzheimer disease in individuals with AD-causing…
- Conditions
- Alzheimers Disease, Dementia, Alzheimers Disease, Familial
- Trial name
- DIAN-TU-002 (NCT06647498)
- Testing
- Remternetug
- Where
- 37 sites in United States, Argentina and 13 more
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Alzheimer Dementia, Caregiver
Telephone-delivered Mindfulness Intervention for African American Dementia Caregivers
This study is assesses the feasibility and acceptability of telephone-delivered mindfulness training designed to alleviate caregiver burden for African-American rural caregivers of individuals with moderate to severe dementia, as…
- Conditions
- Alzheimer Dementia, Caregiver, Dementia Alzheimers
- Trial name
- NCT04058886
- Testing
- Telephone-delivered Mindfulness
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Amyotrophic Lateral Sclerosis, Frontotemporal Dementia
Genetic Study of Familial and Sporadic ALS/Motor Neuron Disease, Miyoshi Myopathy and Other Neuromuscular Disorders
The investigators laboratory has been studying families with a history of ALS for more than 30 years and is continuing to use new ways to understand how genes may play a role in ALS, motor neuron disease and other neuromuscular…
- Conditions
- Amyotrophic Lateral Sclerosis, Frontotemporal Dementia, PLS, Motor Neuron Disease
- Trial name
- NCT01459302
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester