Clinical trials: Fasciculations
Amyotrophic Lateral Sclerosis
Quantitative Neuromuscular Ultrasonography in Amyotrophic Lateral Sclerosis (ALS)
Amyotrophic Lateral Sclerosis (ALS) is a progressive and fatal neurological disease. Nonspecific symptoms lead to a delay in the diagnosis, only confirmed by the electrophysiologic study. Objectives. 1.
- Trial name
- ALS (NCT02507713)
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Motor Neuron Disease
Surface EMG and Ultrasound in MND
Patients with motor neurone disease typically experience relentless motor decline and die within three years of symptom onset from respiratory muscle weakness.
- Trial name
- NCT05314348
- Testing
- High-density surface EMG, Ultrasound
- Where
- United Kingdom
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- King's College Hospital NHS Trust
Fasciculation
Effects of Cisatracurium on Succinylcholine-induced Fasciculations and Myalgia
The purpose of this study is to investigate the effects of different doses of cisatracurium pretreatment on succinylcholine-induced fasciculations and postoperative myalgia.
- Trial name
- NCT02481193
- Testing
- Cisatracurium
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Yangzhou No.1 People's Hospital
Intubating Conditions, Fasciculations
Muscle Relaxation for Short Procedures
Succinylcholine is commonly used for neuromuscular relaxation for short procedures such as rigid bronchoscopy. A more modern alternative is the application of low-dose rocuronium, reversed by low-dose sugammadex.
- Conditions
- Intubating Conditions, Fasciculations, Postoperative Myalgia, Patient Satisfaction
- Trial name
- NCT01902641
- Testing
- Succinylcholine, Rocuronium/Sugammadex, Rocuronium
- Where
- Germany
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Dr. Horst Schmidt Klinik GmbH
Neurologic Symptoms
Fasciculations in Healthy Adults After Consumption of Caffeine: an Ultrasound Study
Fasciculations are clinically defined as spontaneous intermittent contractions of a portion of muscles. Depending on associated symptoms they may be a sign of lower motor neuron disorder.
- Trial name
- NCT05977920
- Testing
- Caffeine
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Zurich Regional Health Center
Fasciculations
Effects of Cisatracurium on Sccinylcholine-induced Fasciculations
To investigate the effects of different doses of cisatracurium pretreatment on succinylcholine-induced fasciculations.
- Trial name
- NCT02502032
- Testing
- Cisatracurium
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Zhuan Zhang
Fasciculation, Succinylcholine
Median Effective Dose of Cisatracurium for the Prevention of Fasciculation Caused by the Injection of Succinylcholine
Succinylcholine is currently the only depolarizing neuromuscular blocker widely used in anesthesia induction and is the drug of choice for rapid sequential anesthesia induction.
- Trial name
- NCT05760976
- Testing
- Cisatracurium
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Yangzhou University