Clinical trials: Fat Loss
Obesity
FB4 (Framingham, Boston, Bloomington, Birmingham, and Baylor)
This study will evaluate the effects of dietary carbohydrate and sugar consumption, independent of energy content, on body fatness and metabolism in a rigorous feeding study.
- Trial name
- NCT03394664
- Testing
- Feeding Study
- Where
- United States
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Obesity, Diabetes
Effect of Pomegranate Extract Intake on Body Composition and Blood Pressure.
Pomegranate has gained widespread popularity since the health effects of the whole fruit, as well as its juices and extracts, have been studied in relation to a variety of chronic conditions such as hypertension, diabetes…
- Conditions
- Obesity, Diabetes, Cardiovascular Disease
- Trial name
- NCT02017132
- Testing
- Pomegranate extract
- Where
- United Kingdom
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Queen Margaret University
Obesity
B195: Effect of Diet-Induced Energy Deficit and Body Fat Reduction on Inflammatory Markers in Obese Subjects
Aim: To dissociate the effects on plasma concentrations of the inflammatory marker c-reactive protein of a negative energy balance and a reduction in body fat stores.
- Trial name
- NCT00302926
- Testing
- energy restriction and maintenance
- Where
- Denmark
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Hair Disease
AGA Biocellular Stem/Stromal Hair Regenerative Study
Purpose The primary objective of this study is to evaluate the safety and efficacy of the use of a biocellular mixture of emulsified adipose-derived tissue stromal vascular fraction (AD-tSVF) and high density platelet-rich plasma…
- Trial name
- STRAAND (NCT02849470)
- Testing
- Intradermal Injection in hair loss, Platelet Rich Plasma, Adipose Derived Stem/Stromal Cells
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Healeon Medical Inc
Gastrointestinal Hormones
Impact of Macronutrient Composition of Energy-restricted Diet and Exercise on Body Composition and Appetite Hormones.
The main aim of this study is to investigate the effect of energy-restricted low and high-carbohydrate diet combined with exercise training on appetite regulatory hormones, subjective appetite and energy intake in overweight and…
- Trial name
- NCT06022315
- Testing
- caloric restrction high carbohydrate low fat diet with exercise training program, caloric restrction high fat low carbohydrate diet with exercise training program
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Obesity, Inflammation
Gene Expression and Inflammation in Overweight Subjects
This study will look at gene expression (whether particular sets of genes are activated ["turned on"] or deactivated ["turned off"]) in overweight people as compared to non-overweight individuals.
- Conditions
- Obesity, Inflammation, Nutrition Therapy
- Trial name
- NCT00344266
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Obesity
Protein and Resistance Exercise to Stop Sarcopenic Obesity Now
The purpose of this study is to examine the separate and combined effects of a high-protein (HP) diet and resistance training (RT) on body composition and potential biological moderators of body weight in women and men >50y.
- Trial name
- PRESS ON (NCT04014296)
- Testing
- High Protein Diet Counseling, Resistance Training Counseling, Intensify Initial Intervention
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Overweight, Obesity
Efficacy of a Tea Catechin Sports Drink for Enhancing Exercise-Induced Fat Loss
The primary objective of this trial is to evaluate the influence of consuming a tea catechin containing sports beverage on body fat mass during exercise-induced weight loss among overweight and obese men and women.
- Trial name
- NCT00692731
- Testing
- 500 mL/day of a beverage providing approximately 625 mg catechins, Control beverage matched for energy and caffeine content
- Where
- 2 sites in United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Provident Clinical Research
Obesity, Visceral Obesity
Nutrition and Energy Restriction for Cancer Prevention
This study evaluates the effect of intermittent calorie restriction versus continued calorie restriction on weight loss, gene expression profile of subcutaneous adipose tissue and abdominal fat distribution.
- Conditions
- Obesity, Visceral Obesity, Weight Loss, Metabolic Diseases
- Trial name
- HELENA (NCT02449148)
- Testing
- Calorie Restriction
- Where
- Germany
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- German Cancer Research Center
Overweight and Obesity, T2DM (Type 2 Diabetes Mellitus)
Effect of Viscous Soluble Fibres on Body Weight
Abstract: Background: Obesity is a global pandemic affects all age groups and is independent risk factors for most chronic diseases. Dietary intervention is an essential component of obesity management.
- Conditions
- Overweight and Obesity, T2DM (Type 2 Diabetes Mellitus), General Population
- Trial name
- NCT03257449
- Testing
- Viscous Fibre
- Where
- Canada
- Volunteers
- 1,268 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Cachexia, Neoplasms
Cancer-associated Muscle Mass - Molecular Factors and Exercise Mechanisms
Muscle mass loss is a common adverse effect of cancer. Muscle mass loss occurs with or without reduction in body weight. Cancer cachexia (CC) is the involuntary loss of body weight of >5% within 6 months and it occurs in 50-80%…
- Conditions
- Cachexia, Neoplasms, Exercise, Metabolism
- Trial name
- PANACEA (NCT05307367)
- Testing
- Exercise training
- Where
- Denmark
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Overweight and Obese Women
Impact of Beta-glucan Supplementation During Calorie and Carbohydrate-restricted Diet on Body Weight and Body Fat Loss, Appetite, and Gastrointestinal Appetite Hormones.
This study will investigate whether beta-glucan supplementation, when added to an energy and carbohydrate-restricted diet, facilitates body weight and body fat loss, and leads to less detrimental changes in subjective appetite…
- Trial name
- NCT07299942
- Testing
- Beta-glucan addition to a restricted calorie of meal replacements and carbohydrate diet.
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Fat Loss
Safety and Efficacy of Cryolipolysis Clinical Protocols
A single-arm, multicenter interventional clinical study will be conducted. The objective is to evaluate the safety and efficacy of the cryolipolysis technique. Approximately 372 participants will be included.
- Trial name
- NCT06541899
- Testing
- Polarys Cryolipolysis
- Where
- 3 sites in Brazil
- Volunteers
- 395 people, healthy volunteers welcome
- Sponsor
- Indústria Brasileira Equipamentos Médicos - IBRAMED
Blood Sugar; High, Overweight and Obesity
Glucagon Like Peptide 1 (GLP-1) Booster™ RCT Study
BACKGROUND GLP1 booster (GB) was designed to stimulate the endogenous production of GLP1, which in turn releases insulin, controls blood glucose level, suppresses appetite and thus helps people lose weight.
- Conditions
- Blood Sugar; High, Overweight and Obesity, Fat Loss, GLP-1
- Trial name
- RCT (NCT07141472)
- Testing
- GB
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Lawry Han
Weight Change, Body, Weight Loss
Study of Human Adipose Tissue (LOSHAT)
The investigators will study the influence of initial fat cell size/number and adipose function (in particular lipolysis) on weight development over very long time periods (years).
- Conditions
- Weight Change, Body, Weight Loss, Weight Gain, Lipolysis
- Trial name
- LOSHAT (NCT03675464)
- Where
- Sweden
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Karolinska University Hospital
Overweight, Obesity
Effect of Chili Pepper Extract on Weight and Fat Loss and Metabolism Increase
The purpose of this study is to test the safety and effectiveness of a purified extract of CH-19 Sweet, containing capsinoids.
- Trial name
- NCT00825838
- Testing
- Chronic consumption of chili pepper extract
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ajinomoto USA, INC.
Overweight and Obese Adults, High Intensity Interval Exercise (HIIE)
Acute Effects of Isoenergetic HIIE vs. MICE on Key Parameters of Fat Mass Loss in Young Females With Overweight or Obesity
Overweight and obesity, particularly increased total and/or abdominal fat mass (FM), are strongly linked to the development of cardiovascular diseases.
- Trial name
- COMEFIT (NCT06868862)
- Testing
- Exercise
- Where
- Brazil
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques
Obesity
Reduction in Cardiovascular Risk Factors and Visceral Adipose Tissue in Men: Separate Effects of Diet- and Exercise-Induced Weight Loss
The purpose of the trial was to examine the independent effects of equivalent diet- or exercise-induced weight loss on obesity and related cardiovascular health risk factors.
- Trial name
- NCT00664547
- Testing
- Diet Weight Loss, Exercise Weight Loss, Exercise Without Weight Loss
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Queen's University
Overweight and Obesity
Is Strength Training a Viable Exercise Modality for Fat Loss?
The purpose of this study is to determine whether strength training can be used as a viable exercise modality for the purpose of inducing fat loss.
- Trial name
- NCT05622149
- Testing
- Diet Only, Training Only, Diet plus Training
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- George Washington University
Physical Activity, Fat Burn
High Intensity Interval Training vs Moderate Continuous Endurance Exercise Training on Program Adherence
This study examines whether high intensity interval training (HIIT) or moderate, continuous endurance exercise training (MCEET) results in greater program adherence when matched for session time.
- Trial name
- NCT03357601
- Testing
- HIIT, MCEET
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Western University, Canada