Clinical trials: Fat Metabolism
Metabolic Syndrome, Obesity
Epicardial Fat Thickness and Inflammation in People With Metabolic Syndrome and Obesity
Epicardial adipose tissue (EAT) is a type of visceral adipose tissue (VAT), functioning as a metabolically active endocrine organ and suggested to play an important role in the progression of metabolic syndrome (MetS).
- Conditions
- Metabolic Syndrome, Obesity, Inflammation
- Trial name
- NCT04437979
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Antalya Training and Research Hospital
Healthy
Screening of Healthy Adults for Genetic Variations That Control Fatty Acid Processing
The purpose of this research study is to screen healthy African American and Caucasian persons for specific differences in genes that control how fats are processed in the body.
- Trial name
- NCT01516125
- Where
- United States
- Volunteers
- 458 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Obesity & Overweight, Healthcare Worker
Personalized Nutrition Coaching for a Weight Loss Program Among Overweight and Obese Nurses
Obesity among healthcare workers has become an increasing public health concern, with potential consequences for work productivity, quality of care, and long-term health outcomes.
- Conditions
- Obesity & Overweight, Healthcare Worker, Low Physical Activity Level
- Trial name
- NCT07440979
- Testing
- Personalized Nutrition Coaching
- Where
- Indonesia
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Universitas Padjadjaran
Obesity, Gender
Work-Related Effects of Heat, Activity, and Fat in Middle Aged Men
Obesity is associated with many undesirable health effects and disease, and middle age is associated with increased risk for disease.
- Conditions
- Obesity, Gender, Problem of Aging
- Trial name
- NCT02532725
- Testing
- Cardiopulmonary Exercise Stress Test, Climatic-Controlled Cardiopulmonary Exercise Stress Test, Body Composition Evaluation
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Freeman-Sheldon Research Group, Inc.
Obesity
Effect of Whole-grape Powder on Body Composition, Fat and Bone Serum Biomarkers in Postmenopausal Women
The purpose of the study is to provide whole-grape powder or a placebo as a supplement to postmenopausal women for 12 weeks to determine the effects on body composition and bone formation.It is hypothesized that 12 weeks of…
- Trial name
- NCT01717820
- Testing
- Freeze-dried whole-grape powder
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Texas Woman's University
Satiety, Appetite
A Study of NatureU Burn on Satiety in Healthy Adults
This single-center, single-blind, non-randomized crossover exploratory study evaluated the short-term effects of NatureU Burn on postprandial satiety in healthy adults.
- Conditions
- Satiety, Appetite, Food Intake, Fat Disorder
- Trial name
- NUBURN (NCT07597382)
- Testing
- Glucose Reference Food, NatureU Burn Plus Glucose
- Where
- China
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- OmniSolutions Laboratory Holdings Limited
Healthy, Metabolic Syndrome
Effect of Cherry Juice on Fat Oxidation and Cardio-metabolic Markers
The present study examined the effect of Montmorency tart cherry juice and FATMAX (intensity eliciting maximal fat oxidation) exercise on fat oxidation rates, body composition and blood-based cardio-metabolic markers.
- Trial name
- NCT02999256
- Testing
- Montmorency Tart Cherry Juice
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Hertfordshire
Morbid Obesity, Steatosis
Very Low Calorie Liquid Diet for Pre op Patients
Despite the relative consensus on the benefits of pre-surgical weight loss, i.e., the reduction of comorbidities associated with surgical act, such as decreased visceral fat, liver volume, hemorrhage perioperative and surgical…
- Trial name
- NCT01748682
- Testing
- A very low calorie diet of two different consistencies
- Where
- Brazil
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Silvia Leite Faria
Healthy Participants, Normal Weight Adults
Blood Glucose Levels After Bread Consumption Between Participants With Normal Weight and Overweight/Obesity
Obesity and increased blood glucose peaks are risk factors for type 2 diabetes mellitus (T2DM). Few studies have explored whether increased body fat contributes to higher blood glucose peaks after food consumption.
- Conditions
- Healthy Participants, Normal Weight Adults, Overweight or Obese Adults
- Trial name
- PPGRB (NCT07158762)
- Testing
- White bread, Wholemeal bread
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- City, University of London
Obesity, Metabolic Syndrome X
Weight and Metabolic Effects of an Almond Enriched Hypocaloric, Low Fat Diet on Overweight and Obese Persons
The purpose of this trial is to study the safety, tolerability and efficacy of an almond enriched hypocaloric diet on weight loss and weight maintenance, as well as on established and emerging cardiovascular risk factors in…
- Conditions
- Obesity, Metabolic Syndrome X, Hyperlipidemia, Hypertension
- Trial name
- NCT00194428
- Testing
- Almond enriched diet, Low fat caloric diet
- Where
- United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Temple University
Insulin Resistance, Obesity
Impact of Trans Fatty Acids From Natural and Industrial Origin in the Induction of Insulin Resistance Development
The investigators' project has as for principal objective to understand the impact of trans fatty acids from dairy products and industrial origin on the development of insulin resistance in obese woman.
- Trial name
- Trans-Insulin (NCT00617435)
- Testing
- vaccenic acid enriched diet, Elaidic acid enriched diet, control diet
- Where
- 2 sites in France
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Obesity
Diet and Body Composition
The investigators hypothesize that differential dynamics in fat depots in response to two opposing dietary strategies mediate the beneficial metabolic effects during weight loss and regain phases.
- Trial name
- CENTRAL (NCT01530724)
- Testing
- Weight-loss diet strategy (+) exercise (PA), weight loss (-) exercise (PA)
- Where
- Israel
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Ben-Gurion University of the Negev
Overweight and Obese Adults, High Intensity Interval Exercise (HIIE)
Acute Effects of Isoenergetic HIIE vs. MICE on Key Parameters of Fat Mass Loss in Young Females With Overweight or Obesity
Overweight and obesity, particularly increased total and/or abdominal fat mass (FM), are strongly linked to the development of cardiovascular diseases.
- Trial name
- COMEFIT (NCT06868862)
- Testing
- Exercise
- Where
- Brazil
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques
Diabetes Mellitus, Type 2, Overweight
Mitochondrial Dysfunction in Type 2 Diabetes Mellitus and Capacity for Fat Oxidation During Exercise
The purpose of this study is to compare the effects of an 8-week aerobic training program upon fat oxidation in vivo and markers of skeletal muscle mitochondrial content and oxidative capacity in sedentary obese subjects with and…
- Trial name
- NCT00382473
- Testing
- Aerobic exercise program - 8 weeks
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Overweight and Obesity
Fitness and Fat Oxidation in Overweight Chinese, Indian and Malay Men
South Asian men have lower cardiorespiratory fitness (CRF) than white men which is associated with a reduced capacity to oxidise fat during exercise. This is a risk factor for weight gain/regain.
- Trial name
- NCT05337111
- Testing
- Cardiorespiratory fitness test, Resting measure of fat oxidation, Maximum fat oxidation test
- Where
- Singapore
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Nanyang Technological University
Obesity, Morbid, NASH - Nonalcoholic Steatohepatitis
Investigating the Link Between Type 2 Immunity and NAFLD in Human Obesity
This study is being done to better understand the relationship between inflammation in adipose tissue (AT), abnormal deposition of fat around the liver and how this affects its appearance and function and ultimately insulin…
- Conditions
- Obesity, Morbid, NASH - Nonalcoholic Steatohepatitis, Chronic Inflammation
- Trial name
- NCT04232566
- Testing
- Bariatric surgery
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Resting Energy Expenditure
Metabolic Effects of Differential Organ Growth Rates
Young children have a high resting energy expenditure (REE) relative to their body weight and metabolically active compartment, fat-free mass (FFM).
- Trial name
- NCT03219229
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Columbia University
Type 2 Diabetes, Cold Acclimation
Chronic Cold Acclimation Stimulates the Browning of Subcutaneous White Adipose in Patients With Type 2 Diabetes Mellitus
Adipose tissues, which include white adipose tissue (WAT) and brown adipose tissue (BAT), play an essential role in regulating whole-body energy homeostasis.
- Trial name
- NCT02775253
- Testing
- Chronic cold acclimation
- Where
- China
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Xiang Guang-da
Overweight and Obesity
Dietary Treatment Study of Fat Synthesis and Risk of Cardiovascular Disease
The purpose of this study is to find out how the amount of fat or sugar in a person's diet, or the number of meals eaten each day, affect the amount of fat that people's bodies make, the types of fats in the bloodstream, and how…
- Trial name
- NCT02075710
- Testing
- High sugar/meal feed, High sugar/nibble, High fat/meal feed
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Obesity
Duration of Vitamin D Stores After Prolonged Vitamin D Substitution
Ingested or skin produced vitamin D is either hydroxylated in the liver to 25-hydroxyvitamin D (25(OH)D), metabolized and excreted in the urine, or stored in adipose and other tissues.
- Trial name
- NCT01729013
- Where
- Norway
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of Tromso