Clinical trials: Fatigability
Adult, Fatigue
Recovery, Fatigability, and Proteomic Response to Aerobic Exercise Training in Healthy Individuals
The purpose of this protocol is to investigate the role of expired non-metabolic carbon dioxide in the relationship between fatigability and recovery and the response to aerobic exercise training in healthy individuals.
- Trial name
- NCT03800342
- Testing
- Aerobic Exercise Training
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- George Mason University
Frailty
Feasibility and Usability of Intrinsic Capacity Monitoring With Eforto and Its Predictive Value for Health Outcomes in Older Community-dwelling Persons
In this study, 160 community-dwelling older adults (65 years and older) will be provided with an eforto® system to self-monitor their muscle fatigability and self-perceived fatigue for 2 consecutive days per week during 12 months…
- Trial name
- FORTO 2 (NCT05368337)
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Osteoarthritis, Osteoarthritis, Knee
Reliability of Measuring Walking-related Performance Fatigability Using Six Minute Walk Test in Persons With Knee Osteoarthritis
Evidence has shown that knee osteoarthritis causes an increase in base of support and a decrease in stride length and gait velocity which results in an increase in energy expenditure during walking.
- Trial name
- NCT04530266
- Testing
- Six minute walk test
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Foundation University Islamabad
Healthy Aging, Fatigue
Neuromodulation and Fatigue
In this project, we aim to determine any potential effects of a weak electrical current applied to the neck or thoracic area on functional capacity and muscle activation.
- Trial name
- NCT05487131
- Testing
- electrical stimulation
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Aging
Fatigability of Lower Limb Muscle in Older Adults: Protective Effects of Strength Training Exercise in Old Men and Women
The proposed studies will assess 1) the mechanisms for the age-related increase in fatigability during dynamic exercise (Aims 1 and 2) and 2) the effectiveness of high-velocity resistance training coupled with blood flow…
- Trial name
- NCT03888040
- Testing
- Exercise
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Marquette University
Multiple Sclerosis, Long Covid
Fatigue Investigation Using Digital Outcomes
This study investigates objective methods to measure and monitor fatigue in patients with post-COVID-19 condition (long COVID) and multiple sclerosis (MS), and includes a group of healthy volunteers for comparison.
- Conditions
- Multiple Sclerosis, Long Covid, Healthy
- Trial name
- FIDO (NCT07783074)
- Where
- 6 sites in Switzerland
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Liliana Barrios
Multiple Sclerosis
Fatigability in Persons With Multiple Sclerosis: Inputs From Cognition, Walking and Coordination
Walking impairments occur in 93% of persons with MS (pwMS) within 10 years of diagnosis. Besides the impact of muscle weakness or hypertonia, one is increasingly aware about the symptom of fatigability.
- Trial name
- NCT05412043
- Testing
- Dance therapy, Psychometric properties (Validity, Reliability) of interlimb coordination- and cognitive-fatigability
- Where
- 2 sites in Belgium
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Fatigue
Fatigability and Cognitive Demand With Aging
This study will determine the influence of a cognitive task performed during fatiguing contractions.
- Trial name
- NCT05121272
- Testing
- cognitive task
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Muscle Spasticity, Paralysis; Cerebral
The Decline in Walking Performance in Adults With Cerebral Palsy - Influence of Performance Fatigability
Due to an early brain injury occurring in antenatal or postnatal, cerebral palsy (CP) causes alteration in motor function with posture and gait disorders.
- Trial name
- FAT-GAIT (NCT06163950)
- Testing
- Fatigability assessment
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Aging
Exercise Fatiguability in Older Adults: The Protective Effects of Dietary Nitrate Supplementation
Vascular and skeletal muscle function decline with age and are associated with decreased nitric oxide (NO) bioavailability. Dietary nitrate supplementation in the form of beet root juice increases NO bioavailability and improves…
- Trial name
- NCT05313490
- Testing
- Beetroot Juice
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Marquette University
Healthy
Tongue Protrusion Assessment in Healthy Adult (FLEPI)
This study aims to evaluate tongue protrusion motor skills in healthy adults and to assess the reliability of these measurements as well as their validity in relation to other motor functions (handgrip and respiratory muscles).
- Trial name
- NCT06169761
- Testing
- Assessment of motor skills of the tongue and others muscles, see below) and risk for sleep apnea
- Where
- Belgium
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Université Catholique de Louvain
Older Women, Older Adults, Balance
Line Dancing With Blood Flow Restriction for Balance and Gait of Older Women (In-Person vs Online)
Falls are a leading cause of injury-related hospitalization among older women. Age-related declines in gait speed and postural stability are known risk-factors for falls.
- Conditions
- Older Women, Older Adults, Balance, Older Adults, Healthy Older Adults in the Community
- Trial name
- NCT07860541
- Testing
- Wearing blood flow restriction, Online dance classes, In-person dance classes
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Concordia University, Montreal
Ankle Sprain, Ankle Instability
Auto-regulated Blood Flow Restriction in Athletes With Recurrent Ankle Sprain
Ankle injuries, especially lateral ankle sprains, are prevalent in physically active individuals. Blood Flow Restriction Training (BFRT) has emerged as a promising method, employing partial arterial occlusion and full venous…
- Trial name
- NCT06962943
- Testing
- Auto-regulated Blood Flow Restriction Training, Non-regulated Blood Flow Restriction Training, Control group
- Where
- United Arab Emirates
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Prince Sattam Bin Abdulaziz University
Frailty, Frailty Syndrome
Characterising Frailty Using Magnetic Resonance Imaging
Ageing is associated with the development of various negative conditions, such as frailty. Defined as a decreased ability to combat negative stressors (e.g.
- Conditions
- Frailty, Frailty Syndrome, Frail Elderly Syndrome
- Trial name
- PHENOFRIM (NCT04612686)
- Where
- United Kingdom
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Aging
Fatigability and Physical Performance: Effects of Resistance Training Variables Manipulation
This study evaluate whether resistance training variables modulate the fatigability (power-duration relationship) and physical performance in adults and older adults
- Trial name
- NCT03619070
- Testing
- Resistance training, LL, Resistance training, HL, Resistance training, HVHL
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Triangulo Mineiro
Muscle; Fatigue, Heart
Fatigability of the Quadriceps Muscle in Non-cooperating Subjects
As the critical care practice has improved over the last decades more patients are recovering from intensive care therapy. However, muscle atrophy and neuromuscular dysfunction are commonly observed sequelae after critical…
- Trial name
- NCT01345461
- Testing
- transcutaneous electrical muscle stimulation, (model DS7A, Digitimer, Welwyn, Garden City, Hertfordshire, UK)
- Where
- Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Fatigue
Impact of Transcranial Direct Current Stimulation on Fatigability and Fatigue Induced by a Selective Attention Task
This research project is focusing on changes in mental fatigue due to transcranial direct current stimulation (tDCS) in healthy individuals.
- Trial name
- NCT02840214
- Testing
- transcranial direct current stimulation
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
PARKINSON DISEASE (Disorder), Aged 65 Years or Older
Multidimensional Assessment of Fatigability in Older Adults Living in Southern Switzerland and Elderly With Parkinson's Disease
With our study, the investigators aim to assess the impact of the fatigue experienced during daily life activities (tiredness) and whether there is a relationship with muscle fatigue during an exercise task.
- Trial name
- LifeLike (NCT07485218)
- Where
- 5 sites in Italy, Switzerland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Applied Sciences and Arts of Southern Switzerland
HIV, HIV Infections
Skeletal Muscle Energetics and Fatiguability in Older Individuals
The investigators are studying whether metabolic abnormalities in calf (leg) muscle in older people with and others without HIV are associated with decreased abilities to exercise.
- Trial name
- NCT04142047
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Aging, Muscle Fatigue
Impacts and Mechanisms of Age and Muscle Fatigue on Postural Control and Force Control
Muscle fatigue is one of the clinical symptoms in elderly people and demonstrates task dependency and muscle dependency. Muscle fatigue has been shown to negatively impact postural control, physical activity, and quality of life.
- Trial name
- NCT07405060
- Testing
- Age, Muscle fatigue
- Where
- 2 sites in Taiwan
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital