Clinical trials: Fatigue
Autonomous Nervous System, Fatigue
Exploring Physiological Responses of Virtual Reality Walking Exercise Versus Treadmill Walking in Healthy Individuals
This study aimed to systematically compare the physiological responses generated by walking exercises conducted in a VR environment versus those performed on a treadmill, with a specific focus on their impacts on the autonomic…
- Trial name
- NCT06679348
- Testing
- walking exercise on treadmill, Treadmill walking exercise using VR
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Atlas University
Multiple Sclerosis
Role of Neuromuscular Junction Function in Motor Fatigue in Multiple Sclerosis
This pilot study will evaluate for the presence of neuromuscular junction (NMJ) defect in women with motor fatigue in multiple sclerosis by Single Fiber Electromyography (SFEMG) using the concentric needle electrode.
- Trial name
- NCT02418897
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Breast Cancer Female, Anxiety
The Effect of Virtual Reality on Anxiety and Fatigue in Women With Breast Cancer Receiving Adjuvant Chemotherapy
It was aimed to determine the effect of virtual reality glasses application on anxiety and fatigue in women with breast cancer receiving adjuvant chemotherapy.
- Conditions
- Breast Cancer Female, Anxiety, Fatigue
- Trial name
- NCT05168696
- Testing
- Virtual Reality Glasses
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Exercise, Fatigue
Alterations in Gait, Strength, and Power After Ruck Marching
The purpose of this study is to determine change in injury risk and performance variables in males and females after walking unloaded and carrying a load with two different distributions (high-pack placement and mid-pack…
- Trial name
- SPARTAN (NCT05309603)
- Testing
- Loaded Walking High, Loaded Walking Mid, Walking
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Breast Neoplasm Female, Symptom Cluster
Effects of a Traditional Chinese Exercise Program on Symptom Cluster in Breast Cancer Patients
The Medical Research Council Framework for Developing and Evaluating Complex Interventions (MRC Framework) will be utilized to develop and evaluate an evidence-based tai chi intervention for managing the symptom cluster of…
- Conditions
- Breast Neoplasm Female, Symptom Cluster, Tai ji
- Trial name
- NCT04190342
- Testing
- control group, tai chi group
- Where
- 2 sites in China
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Charles Darwin University
Aging, Fatigue
Description of Physical Activity Effect on Neuromuscular Fatigue of Older People
There is a decrease in cardiovascular and neuromuscular functions, which leads to reduced performance with advancing age. Physical activity provides health benefits, prevents and treats cardiovascular and neuromuscular disease.
- Trial name
- ACTIFS-AGE (NCT05413590)
- Testing
- Questionnaires completion, Isometric forces, Energy cost
- Where
- France
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Stress, Health Knowledge, Attitudes, Practice
Mindfulness Meditation Versus Physical Exercise: Comparing Effects on Stress and Immunocompetence
The objective of this research project is to examine if including mindfulness meditation or physical exercise at lunch break improve workers' recovery from work stress.
- Trial name
- NCT03728062
- Testing
- Mindfulness meditation, Physical exercise
- Where
- Spain
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Educación a Distancia
Improves Daytime Energy Levels, Reduces Afternoon Energy Crashes and Midday Fatigue
A Clinical Trial to Evaluate the Effects of Adrenal Adapt on Sleep Quality, Daytime Energy, Stress Resilience, and Cognitive Performance.
This is a single-group, open-label, uncontrolled clinical trial designed to evaluate the effects of Adrenal Adapt, a commercially available dietary supplement, on sleep quality, daytime energy, stress resilience, and cognitive…
- Conditions
- Improves Daytime Energy Levels, Reduces Afternoon Energy Crashes and Midday Fatigue, Improves Overall Sleep Quality and Restorative Sleep, Helps People Fall Asleep Faster and Wake Less During the Night
- Trial name
- NCT07893561
- Testing
- Adrenal Adapt
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bioligent
Vitamin b12, Supplementation During Endurance Performance
Effects of Vitamin B12 and Natural Orange Extract, and Their Combination on Physical and Mental Performance
The aim of this study was to determine the effects of a new formulation of vitamin B12, natural orange extract, and their combination on physical and mental performance.
- Conditions
- Vitamin b12, Supplementation During Endurance Performance, Flavonoids, Mental Fatigue
- Trial name
- MECHEPS (NCT07341789)
- Testing
- Vitamin B 12, Natural orange extract, Vitamina B12 + natural orange extract
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Francisco Javier Martínez Noguera
Hunger, Depression
Carbohydrate Rich Drink Reduces Pre-endoscopic Discomfort for Patients Going for Elective Endoscopic Procedures
The study is a randomised controlled trial that aims to evaluate whether carbohydrate loading pre-endoscopy can improve patients' overall satisfaction and is not associated with negative impact on endoscopic quality or increased…
- Conditions
- Hunger, Depression, Anxiety, Vomiting
- Trial name
- NCT05342116
- Testing
- Nestle Preload, Water
- Where
- Singapore
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Tan Tock Seng Hospital
Healthy, Athletes
Evaluation of the Ergogenic Properties of Hesperetin on Exercise-induced Fatigue
Twenty young, healthy, physically active men and women (12~30 years) did a pre-post trial randomized into placebo or HST trials (500 mg/d for two weeks).
- Trial name
- NCT07104734
- Testing
- Hesperetin (Hesperetin trial)
- Where
- Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Lumbar Spinal Stenosis
Effect of Muscle Fatigue on Spinal Imbalance and Motion in Lumbar Spinal Stenosis
This study assesses spinal imbalance and motion in patients with sLSS and elicits fatigue via back exercises and compares spinal imbalance and motion before and after the fatigue exercise and compares these to healthy controls…
- Trial name
- MuscLSS (NCT05309447)
- Testing
- data collection
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Obesity
Effects of Kinesio Taping on Performance
This study investigated the immediate effects of Kinesio taping on muscular power, strength, endurance, and lower limb fatigue when taping is applied to rectus femoris and around the patella of obese adults based on Kinesio…
- Trial name
- NCT02840734
- Testing
- Kinesio taping
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Texas A&M University San Antonio
Muscle Soreness
The Effects of Swedish Massage and Manual Lymph Drainage on Muscle Fatigue
12 healthy men aged 18-30 will be included in the study. Participants will be selected from students who regularly train and do active sports at the Faculty of Sports Sciences. All participants will do nordic hamstring exercise.
- Trial name
- NCT06112899
- Testing
- Nordic Hamstring Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Fatigue Intensity
Myocene Sensivity to Cycling Intensities
This study aims to address this gap by assessing LFF following different efforts in cycling, aiming to identify a pattern. Also, we expect that this study helps to clarify to which efforts (prolonged vs short) are more likely to…
- Trial name
- NCT06913036
- Testing
- Low-frequency fatigue - Myocene
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Maia
Sarcopenia, Fatigue
Association Between Sarcopenia, Fatigue and Orthostatic Intolerance in Geriatric Patients: A Case Control Study
This study aims to explore the relationship between sarcopenia, fatigue, and orthostatic intolerance in older adults. It will be conducted among geriatric patients attending Ain Shams University Hospitals.
- Conditions
- Sarcopenia, Fatigue, Orthostatic Intolerance
- Trial name
- NCT07564830
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Relapsing Remitting Multiple Sclerosis, Fatigue
Correlation Between Daily Physical Activity and Disability, Fatigue, Cognition and Quality of Life in MS Patients
The main purpose of the study is to assess the fatigue, cognition, quality of life and disability correlation to MS-patients daily physical activity.
- Conditions
- Relapsing Remitting Multiple Sclerosis, Fatigue, Quality of Life, Physical Activity
- Trial name
- PAMS (NCT04115930)
- Testing
- Physical Activity measurement:
- Where
- 4 sites in Finland
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland
Neuromuscular Fatigue, Load-velocity Variables
Sensitivity of Load-Velocity Measures for Detecting Fatigue During Smith-Machine Squats
The purpose of this study is to determine whether load-velocity (L-V) relationship variables (L0, v0, and Aline) are sensitive indicators of fatigue produced by different squat fatigue protocols.
- Trial name
- SLV (NCT07307963)
- Testing
- Control Protocol (No Training), Moderate-fatigue, High-fatigue
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Istanbul Gelisim University
Dry Eye, Eye Fatigue
A Randomized Controlled Trial to Evaluate the Safety and Efficacy of an Oral Supplement in Supporting Vision and Eye Health
This is a 4-week virtual randomized, triple-blinded, placebo-controlled clinical trial evaluating the safety and efficacy of Eye Empower, an oral supplement, in adults aged 45 or older experiencing dry eyes, irritation, and…
- Trial name
- NCT07123584
- Testing
- Eye Empower
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bio Nature Health
Chronic Pain, Fatigue
Real-world Momentary Assessment of Kratom Use Accompanied by Product Assays: A Natural-history Study for Interdisciplinary Characterization of Kratom Use and Pharmacology
Background: Mitragyna speciosa, also called kratom, is a plant used in Southeast Asia for its psychoactive effects. Its use has increased in the US, and an estimated 10 million adults may take it at least semiregularly.
- Conditions
- Chronic Pain, Fatigue, Substance Use Disorders
- Trial name
- NCT05457803
- Where
- United States
- Volunteers
- 396 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
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