Clinical trials: Fatty Acids
Healthy
Effects of Omacor and Aspirin on Platelet Function
Omacor (now Lovaza) is a pharmaceutical omega-3 fatty acid product. Omega-3 fatty acids can affect blood clotting by altering the function of the blood platelets. Aspirin can do the same.
- Trial name
- NCT00688961
- Testing
- Aspirin, omega-3 acid ethyl esters
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Sanford Research
Infant Nutrition
Formula With Modified Content of Protein and Improved Fatty Acids and Their Impact on Infant Growth and Health
In this study, the suitability of an infant formula with a modified content of protein and fatty acid pattern (LC-PUFA) for healthy term infants will be investigated.
- Trial name
- BEMIM (NCT01094080)
- Testing
- standard infant formula, modified infant formula, breast milk
- Where
- 2 sites in Germany, Serbia
- Volunteers
- 505 people, healthy volunteers welcome
- Sponsor
- Ludwig-Maximilians - University of Munich
Parkinson Disease
Brain Small Chain Fatty Acid Metabolism in Parkinson Disease: Tributyrin Supplementation
Small exploratory open-label pilot study to assess the short-chain fatty acid (SCFA) prodrug tributyrin as a potential therapy for persons with Parkinson disease
- Trial name
- BUTTER (NCT05446168)
- Testing
- tributyrin
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Nicolaas Bohnen, MD, PhD
Lactation Induced
Effect of OMEGA 3 Fatty Acids on Lactation Period
The World Health Organization (WHO) and the United Nations Children's Fund (UNICEF) recommend that babies be exclusively breastfed for the first 6 months from birth.
- Trial name
- NCT06111378
- Testing
- fish oil, linseed oil, walnut oil
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Manisa Celal Bayar University
Fatty Acids, Omega-3
Evaluation of the Nutritional Status of Omega-3 Fatty Acids and the Possible Influences of Dietary Patterns and Different Socioeconomic Factors, in a Spanish Population Over 60 Years of Age
The long-chain polyunsaturated fatty acids (PUFA) of the n-3 or omega-3 series and, in particular, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), both derived from the essential fatty acid alpha-linolenic acid, are…
- Trial name
- OMEGAPRED (NCT06916455)
- Where
- Spain
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Cancer, Cardiovascular Disease
Vitamin D and Omega-3 Trial (VITAL)
The VITamin D and OmegA-3 TriaL (VITAL) is a randomized clinical trial in 25,871 U.S. men and women investigating whether taking daily dietary supplements of vitamin D3 (2000 IU) or omega-3 fatty acids (Omacor® fish oil, 1 gram)…
- Trial name
- VITAL (NCT01169259)
- Testing
- vitamin D3, omega-3 fatty acids (fish oil)
- Where
- United States
- Volunteers
- 25,871 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Pregnancy, Lactation
The Role of Human Milk in Development of Breast Fed Child's Intestinal Microbiota
The ideal food for normal infants is human milk. In addition, breast milk has been shown to be a continuous source of commensal, and⁄or probiotic bacteria to the infant gut where they play a key role in the initiation and…
- Trial name
- MYMILK (NCT01548313)
- Where
- Slovenia
- Volunteers
- 294 people, healthy volunteers welcome
- Sponsor
- University of Ljubljana
Iron-deficiency
Iron Isotope Study of an Iron Fatty Acid Complex
The study aims at assessing the iron (Fe) bioavailability from a newly developed iron compound - an iron fatty acid complex. The iron from the compound is hypothesized to have a higher absorption rate than commonly available…
- Trial name
- IFAC (NCT03895424)
- Testing
- IFAC, MIFAC, Control Ferrous Sulfate
- Where
- Switzerland
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Hip Pain Chronic, Knee Pain Chronic
Effect of Buglossoides Oil on Recent Chronic Non-injurious Hip and Knee Pain
The effect of Buglossoides oil emulsion on the intensity of recent chronic knee and hip pain, on plasma and mononuclear blood cells fatty acid profiles and on whole blood Eicosapentaenoic acid production will be investigated.
- Trial name
- NCT03576625
- Testing
- High Oleic Sunflower Oil, Buglossoides Oil
- Where
- Canada
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Réseau de Santé Vitalité Health Network
CVD, Cholesterol; Metabolic Disorder
Omega (n)-3 PUFA Enriched Beef & Health Outcomes.
Red meat is an integral component of the habitual diet among the UK and Irish population, with adults consuming an average of 71grams/day.
- Conditions
- CVD, Cholesterol; Metabolic Disorder, Inflammation
- Trial name
- NCT03967678
- Testing
- Three portions per week (690g beef (raw weight)) for 5 weeks
- Where
- United Kingdom
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Vitamin/Nutritional Deficiency, Neurobehavioral Manifestations
Walnuts, Long-Chain Polyunsaturated Fatty Acids and Adolescent Brain Development
Background: Adolescence is an important period for brain development as a result of increased synaptic plasticity. Omega-3 polyunsaturated fatty acids (n-3 PUFAs) are essential nutrients for brain development and protection…
- Trial name
- WALNUTs (NCT02590848)
- Testing
- Walnut intake
- Where
- Spain
- Volunteers
- 730 people, healthy volunteers welcome
- Sponsor
- Barcelona Institute for Global Health
Physical Activity, Healthy
The Effects of Dietary Intake of Cod Residual Material Meal on Lipid Regulation, Glucose Regulation and Body Composition in Physically Active Adults
A high intake of fish is associated with positive health effects, including prevention and treatment of chronic non-communicable diseases, such as cardiovascular diseases (CVDs) and type 2 diabetes.
- Trial name
- COD2016 (NCT03538834)
- Testing
- Cod meal from residual material, Control
- Where
- Norway
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Mania
Neurochemical Effects of Omega-3 Fatty Acids in Adolescents at Risk for Mania
The purpose of this study is to see if taking a substance called omega-3 fatty acids is effective, safe, and well-tolerated for treating adolescents with major depressive disorder (also called simply "depression" or "clinical…
- Trial name
- R34 (NCT00917501)
- Testing
- OMega 3
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Inflammation
Effect of Oleic Acid on Inflammation Markers and Blood Lipid Metabolites: A Randomised, Double-Blind, Crossover Study
Rationale: The effect of positional distribution of dietary fatty acids on markers of inflammation and blood lipids metabolites on diets containing fatty acids such as oleic acid that are associated with reduced risk of…
- Trial name
- NCT00715312
- Testing
- Novel Olein
- Where
- Malaysia
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Malaysia Palm Oil Board
Obesity, Abdominal, Diabete Type 2
Production of Gut Microbiota-Derived Metabolites in Response to Different Fatty Acid Profiles
The proposed project mainly aims to investigate the microbial processes leading to dietary metabolites production, independently of long-term microbiota adaptation to the diet, by measuring the microbiota-derived metabolite…
- Trial name
- METAc (NCT05917132)
- Testing
- Nutritionnal intervention
- Where
- Canada
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Laval University
Obesity, Diabetes
Role of Dietary Fatty Acids in Fatty Liver and Insulin Resistance
The purpose of this study is to investigate whether substituting saturated fats with polyunsaturated fats reduces fatty liver and improves insulin action and other metabolic variables in abdominally obese subjects
- Conditions
- Obesity, Diabetes, Insulin Resistance, Fatty Liver
- Trial name
- HEPFAT (NCT01038102)
- Testing
- PUFA Diet, SFA diet
- Where
- Sweden
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Cardiovascular Prevention
The YOU-Fish Study: Fish and Omega 3 Supplementation in Young Adults
Cardiovascular disease (CVD) is one of the major causes of mortality, however, it is estimated that approximately 75% of all cases are preventable.
- Trial name
- YOU-Fish (NCT06729229)
- Testing
- Dietary Supplement/Vitamins
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Vegetarian Diet
Effects of the Consumption of a Supplement Rich in Docosahexaenoic Acid (DHA) From Algae
Vegetarian diets are increasing worldwide. To prevent nutritional deficiencies, supplementation with nutrients that are only present in animal food can be needed.
- Trial name
- NCT04278482
- Where
- Spain
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- National Research Council, Spain
Lifestyle
Omega-3 Bioavailability From Vegetable-omega-3 Enriched Products
CSIRO's Food Program has developed a novel vegetable-based Omega-3 long-chain polyunsaturated fatty acid (Omega 3)encapsulant to be used as ingredient in various food products, however, it is unknown whether the vegetable-based…
- Trial name
- NCT04610983
- Testing
- Experimental: Control, Experimental: Treatment 1 - Semi-Solid food matrix, Treatment 2 - Solid food matrix
- Where
- 2 sites in Australia, Singapore
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Commonwealth Scientific and Industrial Research Organisation, Australia
Acute Myocardial Infarction
the Association of Intestinal Microbial Metabolites and Cardiac Function in Acute Myocardial Infarction
Recently, more and more studies have confirmed that intestinal flora is closely related to the occurrence and development of cardiovascular diseases.Bile acids (BAS), short chain fatty acids (SCFA) and trimethylamine oxide…
- Trial name
- NCT04955054
- Testing
- diagnose
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital