Clinical trials: FeNO
Asthma, Allergic Rhinitis
PF and FeNO and Clinical Characteristics in Children Being Diagnosed Due to Suspicion of Allergic Diseases
The aim of this study is to assess the influence of kind of allergic disease, allergic profile, allergen exposure, treatment method on lung function parameters, fractional exhaled nitric oxide level in children suspected and…
- Conditions
- Asthma, Allergic Rhinitis, Atopic Dermatitis, Urticaria
- Trial name
- NCT01805635
- Testing
- No intervention
- Where
- Poland
- Volunteers
- 5,500 people, healthy volunteers welcome
- Sponsor
- Medical University of Lodz
Healthy
Investigation of Lungfunction Normal Values in Children and Adolescent in Germany (Spirometry, Ultrasonic Pneumography and Exhaled NO)
Synopsis: LUNOKID-Study Investigation of Lung function Normal Values in Children and Adolescent in Germany For the diagnostic work-up of childhood airway diseases lungfunction measurements play an important role.
- Trial name
- LUNOKID-Studie (NCT00723619)
- Where
- Germany
- Volunteers
- 2,007 people, healthy volunteers welcome
- Sponsor
- Marien Hospital Wesel
Acute Bronchiolitis
FeNO and Cytokines in Respiratory Syncytial Virus (RSV) and Non RSV Bronchiolitis in Relation to Future Asthma
The purpose of this study is to determine Fractional exhaled Nitric-Oxide (FeNO)levels and blood cytokines during acute bronchiolitis, and to seek for correlation between these markers and future development of asthma.
- Trial name
- NCT02093715
- Where
- Israel
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Asthma (Diagnosis), Airway Inflammation
Can Astaxanthin Help Manage Asthma in POlluted Areas?
This study will test whether astaxanthin, a naturally occurring antioxidant supplement, can improve lung function, reduce airway inflammation, and improve asthma control in adults with mild-to-moderate asthma.
- Conditions
- Asthma (Diagnosis), Airway Inflammation, Airway Hyperresponsiveness
- Trial name
- NCT07507682
- Testing
- Astaxanthin Oral Capsule
- Where
- United Kingdom
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Middlesex University
Asthma
The Effect of Single Dose Paracetamol on the Lower Airways of Asthmatic and Healthy Children
Asthma is a common inflammatory airway disease. Several researches have demonstrated a possible connection between asthma and exposure to paracetamol.
- Trial name
- NCT01073748
- Testing
- paracetamol
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Obstructive Sleep Apnea (OSA)
Fractional Exhaled Nitric Oxide as Possible Non - Invasive Biomarker to Assess Obstructive Sleep Apnea Severity
Aim of work 1. Primary aim: Asses correlation between FeNO level, OSA severity 2. Secondary aim: Clarifying FeNO's role as a biomarker to assess airway inflammation, Cut off value prediction to moderate and severe OSA and its…
- Trial name
- NCT07606898
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tanta University
Obstructive Ventilatory Disorders
Study of Chronic Exposure of the Population Living on the Atlantic Coast and on the Caribbean Coast, in Martinique, During the Stranding Period and Outside the Stranding Period of Sargassum Seaweeds
Sargassum are pelagic brown sea algae. Two species grow on the surface of the ocean and drift freely with ocean currents in the form of slicks: the pelagic Sargassum fluitans and Sargassum natans.
- Trial name
- SÉSAR (NCT05564546)
- Testing
- FeNO (fractional exhaled nitric oxide), Spirometry, Physical examination
- Where
- France
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- University Hospital Center of Martinique
Asthma
Impact of FeNO Measured With the NIOX MINO® Device in Identifying Asthma Among Patients With Prolonged Respiratory Symptoms
Overall Aim: To better understand the diagnostic process for prolonged respiratory events and determine the potential role of FeNO in assessing the possibility of asthma as the symptoms etiology.
- Trial name
- NCT01518322
- Testing
- NIOX MINO®
- Where
- 13 sites in United States
- Volunteers
- 235 people, healthy volunteers welcome
- Sponsor
- Aerocrine AB
E Cigarette Use
Circuit Breathing Exercise on Smoking Cessation Among Youth E-Cigarette Users
This study aims to investigate the acute effects of a circuit breathing intervention on nicotine withdrawal symptoms and respiratory parameters among youth who use e-cigarettes.
- Trial name
- NCT07886099
- Testing
- Circuit breathing, Diaphragmatic Breathing, Normal Breathing Condition
- Where
- Thailand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Older Adults (60 - 85 Years Old)
Multiple Breathing Training on Pulmonary Function and Respiratory Muscle Strength in Older Adults
This study were to investigate the effects of multiple breathing training on pulmonary function, respiratory muscle strength, chest expansion, fractional exhaled nitric oxide (FeNO), aerobic capacity, and dyspnea symptoms in…
- Trial name
- NCT07459153
- Testing
- Multiple breathing training
- Where
- Thailand
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Asthma
CIVETTA: Correlating Inflammatory Values of FEno, SympToms, SpuTum and Lung Function in Asthma
Single-center, interventional, open-label, randomized phase II study aimed at describing the changes in airway inflammation at the onset of asthma symptoms that lead to the use of rapid acting bronchodilator (RABD) as a rescue…
- Trial name
- NCT06482294
- Testing
- Salbutamol, Fluticason either Beclometasone or Budesonide
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Università degli Studi di Ferrara
Air Pollution Exposure, Oxidative Stress
Savannah Environmental Nutrition Study (SENS): Nutrition Intervention to Reduce Air Pollution-Related Airway Inflammation and Oxidative Stress
This pilot clinical trial will evaluate the feasibility and potential health effects of a nutrition-based intervention among adults living in communities affected by air pollution near the Port of Savannah, Georgia.
- Conditions
- Air Pollution Exposure, Oxidative Stress, Airway Inflammation
- Trial name
- NCT07797413
- Testing
- Antioxidant- and Nutrient-Rich Food-Based Nutrition Intervention
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Georgia Southern University
Subjective Discomfort, General Mucosal Irritation
Controlled Human Exposure to Indoor Air, Dust and Ozone
The aim of the study is to provide information which may help to improve the quality of the life of persons exposed to indoor environments in Danish dwellings.
- Conditions
- Subjective Discomfort, General Mucosal Irritation, Acute Changes in Respiratory Outcomes, Acute Changes in Cardiovascular Outcomes
- Trial name
- XDOZ (NCT02017782)
- Testing
- Dust, Ozone, Dust and Ozone
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Pulse Spectrum Analysis, Pulmonary Function
Pulse Spectrum Analysis in Adult Asthmatics: Correlation With Lung Function, Asthma Control Exhaled Nitric Oxide and Metabolites in Exhaled Breath Condensate
Our hypothesis is that radial arterial pulse may reflect the severity and airway function in asthmatics. The aims of this study are to investigate the pulse spectrim of the radial artery in adult asthmatics, and evaluate its…
- Conditions
- Pulse Spectrum Analysis, Pulmonary Function, FeNO, Metabolites
- Trial name
- NCT01719393
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
OSA
Fractional Exhaled Nitric Oxide and CRP Levels in Egyptian Patients With Obstructive Sleep Apnea Syndrome
Obstructive sleep apnea syndrome (OSAS) was associated with upper and lower respiratory tract inflammation, Fractional exhaled nitric oxide (FeNO) proposed as a marker of airway inflammation, few studies were done on the impact…
- Trial name
- NCT04179942
- Testing
- Fractional exhaled nitric oxide and CRP levels
- Where
- Egypt
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Asthma
Usefulness of Exhaled Breath Condensate for Evaluation of Markers of Airway Inflammation in Children With Asthma
Exhaled breath condensate (EBC) has emerged as a novel noninvasive technique for assessment of airway inflammation, and it provides information on airway lining fluid composition.
- Trial name
- NCT00961155
- Testing
- cyklezonid, montelukast sodium, formoterol 12 mcg twice daily
- Where
- Poland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Medical University of Lodz
Asthma, Healthy
Inflammatory Markers in Exhaled Breath (Condensate) in Childhood Asthma
Background: Exhaled nitric oxide and inflammatory biomarkers in exhaled breath condensate may be useful to diagnose and monitor childhood asthma.
- Conditions
- Asthma, Healthy, Children
- Trial name
- NCT00404976
- Where
- Netherlands
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Normal Non-fluency
Measurements of Exhaled Nitric Oxide in Healthy Subjects in Thailand
The purpose of this study is to determine fractional exhaled nitric oxide (FeNO) level in healthy subjects among Thai populations.
- Trial name
- FeNO_nor (NCT02554617)
- Where
- Thailand
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Bronchial Asthma, Airway Disease
FeNO Detection in Asthma Diagnosis: A New Technology Approach
The detection of exhaled nitric oxide (FeNO) represents a non-invasive, safe, and rapid approach for assessing endogenous nitric oxide (NO) levels within the airway.
- Trial name
- NCT06852911
- Testing
- Chemiluminescent FeNO Analyzer, Electrochemical FeNO Analyzer
- Where
- 2 sites in China
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Novlead Inc.
Asthma
Achieving Control of Asthma in Children In Africa
The main aim of the study is to identify altogether 3000 children aged between 12 and 16 years old with asthma symptoms in six sub-Saharan African countries.
- Trial name
- ACACIA (NCT03990402)
- Where
- 6 sites in Ghana, Malawi and 4 more
- Volunteers
- 3,767 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London