Clinical trials: Feasibility Pilot Study
Depression, Anxiety Disorders
Pilot Feasibility Study of Remote Problem Management Plus for Adults Affected by COVID-19
This is a pilot feasibility study of remotely delivered Problem Management Plus, a low-intensity psychological intervention, delivered in five sessions to adults affected by crisis.
- Conditions
- Depression, Anxiety Disorders, Psychological Distress
- Trial name
- PM+ (NCT04617262)
- Testing
- Remote Problem Management Plus
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- The New School
Gastric Carcinoma
Risk Assessment Evaluation for Identifying Participants at High Risk for Stomach Cancer
This clinical trial evaluates the usefulness of various risk assessment tests, including Helicobacter pylori (H. pylori) breath testing, questionnaires, and endoscopies for identifying participants at high risk for stomach…
- Trial name
- NCT06408220
- Testing
- Biopsy, Biospecimen Collection, Breath Test
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Ulcerative Colitis
A Pilot and Feasibility Study of Fecal Microbiota Transplantation for Ulcerative Colitis
The investigators are conducting an open-label study of fecal microbiota transplantation (FMT) for adult patients with mildly-moderately active ulcerative colitis.
- Trial name
- NCT02058524
- Testing
- fecal microbiota transplantation
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Depression, Major Depressive Disorder
Feasibility and Acceptability of a Healthy Nordic Diet Intervention in Depressed and Non-depressed Adults
In the future, we plan to conduct an 8-week diet intervention to investigate whether a healthy Nordic diet improves depression symptoms.
- Trial name
- NCT04731454
- Testing
- Control Diet (CD), Healthy Nordic Diet (ND)
- Where
- Sweden
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Örebro University, Sweden
Bowel Cancer Screening
Using Patient Navigation to Promote Bowel Screening in AAA Attendees.
The goal of this single-arm, multi-centre feasibility study is to assess the efficacy, feasibility and acceptability of implementing patient navigation across Abdominal Aortic Aneurysm (AAA) screening services in England to…
- Trial name
- TET BETA (NCT07721740)
- Testing
- Patient Navigation conversation
- Where
- United Kingdom
- Volunteers
- 4,190 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Abortion, 3 Months
A Pilot of an Outpatient Regimen of Medical Abortion With Mifepristone and Sublingual Misoprostol in the 11 and 12 Weeks
A pilot study on the acceptability and feasibility with Mifepristone and 400 mg of sub-lingual Misoprostol between 71-77 and 78-84 days of gestation for 50 cases.
- Trial name
- NCT02720991
- Testing
- Mifepristone, Sublingual misoprostol
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Pain, Acute
Low Dose Methoxyflurane for Pain Relief During Minor Out-patient Urologic Procedures
The participant will be trained to self administer the drug and will be supplied with a PENTHROX commercial inhaler kit .The study nurse will train the participant and supervise its use during the procedure.Immediately following…
- Trial name
- NCT04412642
- Testing
- Methoxyflurane, MEOF
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Cognition, Aged
WhatsApp Intervention for Seniors' Digital and Cognitive Management (WISDOM)
The goal of this clinical trial is to learn if a digital health literacy program using mobile phone chat-based application called WISDOM (WhatsApp Intervention for Seniors' Digital and cOgnitive Management) can help older adults…
- Conditions
- Cognition, Aged, Digital Health Literacy
- Trial name
- NCT07161674
- Testing
- Digital health literacy program
- Where
- Singapore
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Psychological Stress
Mantra Meditation to Reduce Emotional Exhaustion in Emergency Department Staff
Work in a healthcare setting, such as in an emergency department (ED), while rewarding, can be harmful to psychological well being, as demonstrated by the high numbers of Irish hospital doctors experiencing burnout.
- Trial name
- NCT02887300
- Testing
- Mantra Meditation
- Where
- Ireland
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- St. James's Hospital, Ireland
Helminthiasis, Intestinal Worms
Co-administration of IVM and ALB in School-based Deworming in Uganda
The goal of this small-scale implementation research pilot study is to assess the feasibility and acceptability of the co-administration of ivermectin (IVM) and albendazole (ALB) compared to albendazole alone during school-based…
- Trial name
- FACE-ITpilot (NCT06497075)
- Testing
- Albendazole 400mg, Ivermectin 3 MG
- Where
- 2 sites in Uganda
- Volunteers
- 8,767 people, healthy volunteers welcome
- Sponsor
- Jennifer Keiser
Stroke, Complication
A Pilot Study on the Feasibility Study of a Novel Virtual Reality (VR)-Based Post-stroke Hemineglect Evaluation System
The normal value of the new virtual reality (VR)-based hemineglect evaluation system is obtained and its validity is checked by whether there is a difference in the evaluation results between normal people, stroke patients with…
- Trial name
- NCT05145699
- Testing
- VR-based post-stroke hemineglect evaluation system
- Where
- South Korea
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Critical Illness, Delirium in the Intensive Care Unit
Pilot Feasibility Study of a Pragmatic Mixed-Methods Randomized Controlled Trial on a Follow-Up Bundle of Care for ICU Survivors and Caregivers
~80% of ICU survivors experience profound long-term cognitive, physical, and psychiatric impairments known as post-intensive care syndrome (PICS).
- Trial name
- IMPACT-ICU (NCT06681649)
- Testing
- Intervention
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Queen's University
Gut Health
A Study to Evaluate Efficacy of Different Natural Ingredients in Improving Gut Health in Adults With Leaky Gut.
The present study is a randomized, placebo-controlled, double-blind, parallel group study to assess the gut health effects of IP as compared to a placebo in overweight individuals experiencing gut issues.
- Trial name
- NCT05952232
- Testing
- PA-GH-01, MK-GH-04, TSH-GH-03
- Where
- 2 sites in India
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Vedic Lifesciences Pvt. Ltd.
Down Syndrome, Physical Inactivity
GameSquad for Adults With Down Syndrome
The investigators are assessing acceptability, appropriateness, and feasibility of the adapted GameSquad-DS intervention using validated scales alongside qualitative data among young adults with Down Syndrome.
- Trial name
- NCT05473247
- Testing
- Ring-Fit Adventure Group
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Diabetes Mellitus, Stress, Psychological
A Mind-Body Intervention for Diabetes Management: A Pilot Study
Managing type 1 diabetes is stressful. Stress physiology influences glucose metabolism. Continuous glucose monitors allow us to track glucose variability in the real-world environment.
- Conditions
- Diabetes Mellitus, Stress, Psychological, Stress, Physiological
- Trial name
- NCT04944264
- Testing
- Stress Management and Resiliency Training (SMART) program
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Alcohol Use Disorder
Alcohol Brief Intervention Plus Personalized Mobile Chat-based Intervention to Reduce Alcohol Misuse in an Emergency Department
This project focuses on patients in AED. Objectives of this project are: 1. To examine the factors associated with alcohol drinking and alcohol use disorder 2.
- Trial name
- NCT03823599
- Testing
- Mobile chat-based instant messages, Alcohol brief intervention
- Where
- Hong Kong
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Gastric Cancer
Pilot Study of Stomach Cancer Early Detection and Prevention With Endoscopy
Screening esophagogastroduodenoscopy (EGD )provides three distinct opportunities to decrease gastric cancer (GC) morbidity and mortality.
- Trial name
- NCT05566899
- Testing
- esophagogastroduodenoscopy (EGD)
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Polypharmacy, Multiple Chronic Conditions
Protocol for a Multi-site Pilot Study of the OptiMed Clinical Trial
Background: Optimal medication management is one of the essential preconditions for polymedicated home-dwelling older adults with multiple chronic conditions to remain at home and preserve their quality of life and autonomy.
- Trial name
- OptiMed (NCT06688591)
- Testing
- Intervention programme to optimise medication management and prevent MRPs
- Volunteers
- healthy volunteers welcome
- Sponsor
- HES-SO Valais-Wallis
Clostridium Difficile
Effectiveness of Isolating Clostridium Difficile Asymptomatic Carriers on the Incidence of Infections
Background: There is an urgent need to develop new strategies to prevent Clostridium difficile infections (CDI). A recent study suggests that a novel infection control bundle (IC bundle) can lead to a significant decrease in the…
- Trial name
- EFFICACI (NCT03223415)
- Testing
- Detection and isolation of C. difficile carriers
- Where
- 5 sites in Canada
- Volunteers
- 4,138 people, healthy volunteers welcome
- Sponsor
- Yves Longtin
Lung Cancer
MRI and Biomarkers for Lung Nodules Detected During Lung Cancer Screening
The primary objective of this pilot observational study is to evaluate the accrual and retention rate of a study population from a centralized lung cancer screening program to support MRI and blood-based biomarker research for…
- Trial name
- NCT05699213
- Testing
- Lung MRI, Blood Draw
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center