Clinical trials: Feasibility Pilot Study
Hepatitis C
Pilot Study on the Feasibility of Systematic Hepatitis C Screening of Hospitalized Patients
The Ministry of Health has set the target of eradicating hepatitis C (HCV) in France by 2025. The goal is to validate the feasibility and value of conducting routine HCV screening in hospitalized patients.
- Trial name
- HOSPI-VHC (NCT04405024)
- Testing
- Hepatitis C testing
- Where
- 4 sites in France
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Physical Performance Parameters, Exercise Recovery
Effects of Beef-Forward Ready-to-Eat Meals on Recovery Following Simulated Fire Suppression Activities
This clinical trial aims to determine whether consuming beef-based protein before and after physically demanding simulated firefighting activities improves recovery, physical performance, and cognitive performance in healthy…
- Conditions
- Physical Performance Parameters, Exercise Recovery, Cognition, Muscle Damage
- Trial name
- FIRE-BEEF (NCT07822048)
- Testing
- Beef-Based Protein Ready-to-Eat Meals, Plant-Based Protein Ready-to-Eat Meals
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sam Houston State University
Distress, Psychological, Depression - Major Depressive Disorder
Relief From Stress Via Social Protection in Senegal
Despite the growing prevalence of mental health disorders in low- and middle-income countries, significant barriers to seeking and accessing mental health services persist.
- Conditions
- Distress, Psychological, Depression - Major Depressive Disorder, Generalized Anxiety Disorder (GAD)
- Trial name
- RESTORE (NCT06698471)
- Testing
- Community worker training, Referral to Health System
- Where
- Senegal
- Volunteers
- 748 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Cancer Survivors, African Americans
Grateful Strides Toward Physical Activity and Well-Being for Black Breast Cancer Survivors
This pilot study will assess the feasibility of a gratitude intervention to promote physical activity, and well-being and positively impact biomarkers of health among older African American breast cancer survivors.
- Conditions
- Cancer Survivors, African Americans, Women, Psychology, Positive
- Trial name
- NCT05473026
- Testing
- Gratitude Intervention
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Florida
Stress, Depression
Sinasprite: A Pilot Feasibility Study for Patients With Anxiety or Stress
The investigators are proposing a prospective one-arm cohort study testing the feasibility of a game designed to improve symptoms in adults with mild levels of stress, depression, and anxiety.
- Conditions
- Stress, Depression, Anxiety
- Trial name
- NCT02955784
- Testing
- Sinasprite Mobile App
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Madigan Army Medical Center
Delirium - Postoperative
Effectiveness of Electroencephalography Guided Anesthesia
This study will use brain wave information, known as electroencephalography (EEG), to help guide anesthesia delivery during surgery.
- Trial name
- EEG Anesthesia (NCT07567729)
- Testing
- EEG-guided anesthesia training program for anesthesia providers, EEG-Guided Intervention
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Stanford University
Neurofibromatosis 1, Noonan Syndrome
Acceptance and Commitment Therapy for Caregivers of Children With a RASopathy: An Internal Pilot Feasibility Study and Follow-up Randomized Controlled Trial
Background: RASopathies are a group of genetic diseases that affect a child s development. They cause physical, cognitive, and behavioral symptoms. Caring for a child with a RASopathy can be stressful.
- Conditions
- Neurofibromatosis 1, Noonan Syndrome, Legius Syndrome, Cardiofaciocutaneous Syndrome
- Trial name
- NCT05361811
- Testing
- Waitlist, ACT Intervention
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Malignant Female Reproductive System Neoplasm
Physiatry-Led Cancer Prehabilitation During Neoadjuvant Systemic Therapy to Improve Function in Stage III-IVA Gynecologic Cancer Patients
This clinical trial studies whether physiatry-led cancer prehabilitation can be used during systemic treatment before surgery (neoadjuvant systemic treatment [NST]) to improve function in stage III-IVA gynecologic cancer…
- Trial name
- NCT07608445
- Testing
- Educational Intervention, Goal Setting, Interview
- Where
- 2 sites in United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
HIV Infection
Text Messaging to Improve HIV Testing Among Young Women in Kenya
The purpose of this study is to determine whether regularly scheduled HIV sensitization text messages (SMS) are effective in increasing HIV testing rates among young women in Kenya.
- Trial name
- T2T (NCT02527135)
- Testing
- Weekly HIV sensitization text messages
- Where
- Kenya
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Washington
Induced; Birth, Labor Long
Stimulation Therapy for Inducing Mothers
This is a pilot feasibility and acceptability study of a randomized clinical trial of pregnant women at 36 weeks of gestation and greater randomized to one of two arms at Yale New Haven Hospital: (1) Breast stimulation by hand or…
- Conditions
- Induced; Birth, Labor Long, Labor Pain, Breast Pumping
- Trial name
- STIM (NCT04756089)
- Testing
- Electronic breast pump, Exogenous oxytocin intravenous infusion
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Yale University
Colorectal Cancer
Pilot Study in a Company in Maine-et-Loire to Evaluate the Feasibility, Acceptability, and Impact on the Participation Rate of Awareness of Colorectal Cancer Screening by Occupational Health Teams
The main objective of this pilot study is to implement an awareness campaign for colorectal cancer screening in the workplace, in partnership with the staff of the occupational health service of one of the largest companies in…
- Trial name
- NCT03458949
- Testing
- awareness campaign
- Where
- France
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Cardiovascular Diseases, Cerebral Infarction
Screening, Early Referral and Lifestyle Tailored E_prescription for Cardiovascular Prevention
We will evaluate an e_Prescription intervention can be integrated into an electronic screening program, which together exploit: (i) reach - the adult population has 100% mobile phone ownership and 92% internet national coverage…
- Conditions
- Cardiovascular Diseases, Cerebral Infarction, Type2 Diabetes Mellitus, Hypertension,Essential
- Trial name
- SELECT (NCT04082091)
- Testing
- SELECT mHealth Program
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Lung Cancer
MRI and Biomarkers for Lung Nodules Detected During Lung Cancer Screening
The primary objective of this pilot observational study is to evaluate the accrual and retention rate of a study population from a centralized lung cancer screening program to support MRI and blood-based biomarker research for…
- Trial name
- NCT05699213
- Testing
- Lung MRI, Blood Draw
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
HIV Prevention
Supporting Oral and Long-acting PrEP Decision Making Among Pregnant Women in Lilongwe, Malawi
Purpose: The overall objective of this pilot study is to evaluate the feasibility, acceptability, and appropriateness of a shared decision-making (SDM) intervention to support personally appropriate decision making about…
- Trial name
- NCT06397690
- Testing
- My Choice for HIV Prevention (MyChoice), Standard of care (control arm)
- Where
- Malawi
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Underweight, Malnutrition
Study of Effect of Microfinance on Under 5 Health in Rural India
Investigators propose a feasibility and pilot study for a cluster randomised controlled trial. The proposed trial will evaluate the effects of an economic intervention (microfinance) in self-help groups of poor and marginalised…
- Trial name
- NCT01845545
- Testing
- Early provision of microfinance
- Where
- India
- Volunteers
- 2,469 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Physical Activities, Exercise
Investigating the Feasibility and Acceptability of Co-created Intervention to Improve Women's Participation in Muscle-strengthening Exercises
This study will utilise the Randomised Controlled Trial (RCT) design. Following completion of the baseline measurements, participants will be randomly assigned to either the control group or the intervention group.
- Conditions
- Physical Activities, Exercise, Muscular Strength, Healthy Women
- Trial name
- WISH (NCT07095322)
- Testing
- Strength Education Session, Gym Membership, Group Exercise Session
- Where
- United Kingdom
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Insulin Resistance, Hyperinsulinemia
Graded Insulin Suppression Test P&F
The goal of this study is to learn about how the hormone insulin controls blood sugar in a variety of people. The main question it aims to answer is about how much insulin the body actually needs to maintain a normal blood sugar…
- Conditions
- Insulin Resistance, Hyperinsulinemia, Obesity, Healthy
- Trial name
- GIST (NCT06592261)
- Testing
- Insulin regular, 2.0-3.2 mU/m2/min (euinsulinemia), Insulin regular, 32 mU/m2/min (hyperinsulinemia), Octreotide Acetate, 6-45 ng/kg/min
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Columbia University
Healthy
Pilot Study to Assess Feasibility, Reliability and Validity of the e-SSRS-IVR
The proposed study is designed to evaluate the clinical contents of the e-SSRS-IVR with respect to 1.the intent of the instrument (assess face and content validity), 2. system validation with respect to programming integrity, 3.
- Trial name
- e-SSRS-IVR (NCT00921466)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Rogers Center for Research & Training, Inc.
Obesity
Efficacy and Feasibility of an Intermittent Weight Loss Program.
The goal of the study is to measure the effect of an approach including phases of active weight loss broken by weight stabilisation periods (named intermittent weight loss) on the metabolic profile.
- Trial name
- NCT00395356
- Testing
- calorie controlled diet
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Gynecologic Cancer, Anemia, Iron Deficiency
Ferric Derisomaltose/Iron Isomaltoside and Outcomes in the Recovery of Gynecologic Oncology ERAS
Iron deficiency has been reported in up to 35% of patients with a gynecologic malignancy. These patients often require surgical intervention to determine the stage and to treat their illness.
- Conditions
- Gynecologic Cancer, Anemia, Iron Deficiency, Surgery
- Trial name
- FORGE (NCT05467319)
- Testing
- Ferric Derisomaltose Injection, Normal saline
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Alberta Health Services, Calgary