Clinical trials: Febrile Illness
Malaria
Impact of Enhanced Health Facility Care in Uganda
The investigators propose to assess whether an intervention to build capacity and improve delivery of drugs and diagnostics at government-run health facilities improves the health of children and quality of care delivered, as…
- Trial name
- NCT01024426
- Testing
- Enhanced health facility-based care, Standard care
- Where
- Uganda
- Volunteers
- 25,000 people, healthy volunteers welcome
- Sponsor
- Uganda Malaria Surveillance Project
Sepsis, Primary Myopathies
Muscle Force Assessment in the Intensive Care Unit and in Primary Myopathies
The primary aim of the project is to apply the non-invasive stimulated muscle force assessment system to i) intensive care unit patients and ii) patients with primary myopathy or subclinic myopathy (e.g., Duchenne muscular…
- Trial name
- NCT00735384
- Where
- Switzerland
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Fever, Malaria
Use of Malaria Rapid Diagnostic Tests as a Decision Aid for the Management of Fever by International Travelers
This study is part of a larger prospective cohort study (JOKA), designed to study the incidence and etiological spectrum of febrile illness occurring during a travel to the tropics, as well as clinical course, care, treatment and…
- Trial name
- JOKA-I (NCT02900079)
- Testing
- rapid diagnostic test for malaria antigen
- Where
- Belgium
- Volunteers
- healthy volunteers welcome
- Sponsor
- Institute of Tropical Medicine, Belgium
Febrile Illness
Timmy3 Module Clinical Accuracy ISO 80601-2-56:2017 + A1 2018
The purpose of this document is to validate the clinical accuracy of the TIMMY3 thermometry module, integrated into host device CVSM, according to ISO 80601-2-56:2017 + A1 2018.
- Trial name
- NCT06056011
- Testing
- Connex CVSM with Timmy3 module
- Where
- 5 sites in United States
- Volunteers
- 373 people, healthy volunteers welcome
- Sponsor
- Baxter Healthcare Corporation
Fever, Febrile Illness
Fever and Febrile Support for Parents and Carers of Children 2016
To assess the suitability and user-friendliness of an information leaflet for parents on management of fever and febrile illness in children.
- Trial name
- NCT02903342
- Testing
- Leaflet
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University College Cork
Dengue Fever, Fever
Prospective Surveillance of Febrile Illness for Dengue-Endemic Areas in Asia
The purpose of this study is to detect acute febrile episodes and dengue infection in five Asian countries, to assess dengue seroprevalence, and to assess surveillance infrastructure at investigational sites in anticipation of a…
- Trial name
- NCT01218906
- Where
- 11 sites in Indonesia, Malaysia and 3 more
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Sanofi
Fever, Infection
Personalised Risk Assessment in Febrile Illness to Optimise Real-life Management Across the European Union (PERFORM)
Childhood fever is a prevalent problem. Most febrile children who visit hospital improve without treatment, but a minority require treatment, and a few will have severe disease.
- Conditions
- Fever, Infection, Inflammation
- Trial name
- PERFORM (NCT03502993)
- Testing
- Validation of biomarker
- Where
- United Kingdom
- Volunteers
- 7,247 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Dengue, Dengue Vaccines
This Study Will Describe the Burden of DENgue Fever Virus (DENV) Illness Among Household Members Aged 6 Months to 50 Years of Selected Communities in Latin America and Southeast Asia
The purpose of this study is to describe the burden of DENV illness among household members aged 6 months to 50 years of selected communities in Latin America and Southeast Asia.
- Trial name
- NCT02766088
- Testing
- Blood sample collection
- Where
- 2 sites in Mexico, Philippines
- Volunteers
- 1,750 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Acute Febrile Illness
Clinical Study of Transcriptome-based Diagnostic Biomarker for Acute Febrile Illness
Acute febrile illness is the main cause of outpatient visits，and bacterial and viral infections remains the most common cause. The diagnosis of infection is still based on symptoms and traditional techniques, resulting in overuse…
- Trial name
- NCT06552975
- Testing
- Infection
- Where
- China
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Qilu Hospital of Shandong University
Febrile Illness Acute, Inflammation
The Effects of Amino Acid Supplement During Acute Inflammation.
The purpose of the study is to investigate the metabolic effects during acute inflammation with and without the nutritional supplement of amino acids. E.
- Conditions
- Febrile Illness Acute, Inflammation, Metabolic Diseases
- Trial name
- NCT01705782
- Testing
- E. coli endotoxin, US standard
- Where
- Denmark
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Healthy, Febrile Illness
Comparison of Thermometry in Canada for Pediatrics
Compare and assess the accuracy and reliability of the InstaTemp MD® device to techniques presently in use for measuring temperature in infants and children in a Canadian clinical setting.
- Trial name
- CIT-CRCP (NCT03147534)
- Testing
- InstaTemp MD, "Welch Allyn", rectal, "Welch Allyn", oral
- Where
- 2 sites in Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- ARC Devices
Dengue
A Cohort Study to Determine the Incidence of Dengue Fever and to Build Capacity for Dengue Vaccine Trials in Dengue-endemic Regions of South Asia
The purpose of this study is to determine the incidence of dengue fever and to build capacity for dengue vaccine trials in dengue-endemic regions of South Asia.
- Trial name
- NCT02570152
- Testing
- Blood sample collection
- Where
- Sri Lanka
- Volunteers
- 2,004 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Febrile Illness
Village Malaria Worker Expansion
This project will conduct pragmatic operational research in rural communities served by approximately 12 health centres and 120 village malaria workers in Battambang/Pailin, western Cambodia.
- Trial name
- CAM-VMW (NCT05045547)
- Where
- Cambodia
- Volunteers
- 7,191 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Malaria, Non-malarial Febrile Illness
Non-malarial Febrile Illness in Children in Areas of Perennial Malaria Transmission
To evaluate the causes of non-malarial febrile illness in children living in an area of perennial malaria transmission and to determine if these children who test negative for malaria by rapid diagnostic test receive any benefit…
- Trial name
- NCT01043744
- Testing
- Artemether-Lumefantrine
- Where
- 2 sites in Tanzania
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Travel-Related Illness, Malaria
Infection Tracking in Travellers. The Project Aims to Identify Profiles of Travel-associated Illness and to Follow up on Long-term Sequelae of Arboviral Infections and Malaria
The investigators hypothesize that sex, age, area of exposure and purpose of travel are associated with different travel-related infections. The investigators also hypothesize that certain infections will have long-term sequelae.
- Conditions
- Travel-Related Illness, Malaria, Dengue, Chikungunya
- Trial name
- ITIT (NCT04672577)
- Testing
- Observational study
- Where
- Switzerland
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Patricia Schlagenhauf
Enteric Fever, Acute Febrile Illness
Transcriptomic Responses for the Identification of Pathogens
Acute undifferentiated febrile infection (AUFI) is a common presenting syndrome in low-resource settings and better diagnostics are urgently needed to improve patient management and guide disease prevention interventions.
- Conditions
- Enteric Fever, Acute Febrile Illness, Typhoid, Paratyphoid Fever
- Trial name
- TRiP (NCT04878549)
- Testing
- 5-gene transcription signature
- Where
- India
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of Sheffield
Fever
Hospital Admissions in Children Aged 3 Months to 5 Years Presenting With Fever to the Emergency Department
This study primarily aims to describe factors associated with hospitalisation of children aged 3 months to 5 years presenting with fever to an urban paediatric A\&E departments by describing and analysing characteristics both of…
- Trial name
- NCT01196793
- Where
- 2 sites in Switzerland, United Kingdom
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Imperial College Healthcare NHS Trust
Respiratory Infection
Unclogging the Pediatric Emergency Room: Impact of Rapid Viral Diagnostics
Acute respiratory tract infections are among the most common problems of childhood, particularly among infants and children younger than 3 years, and account for most antibiotic prescriptions to children.
- Trial name
- NCT00278759
- Testing
- Nasopharyngeal washing for viral antigen detection by immunofluorescence initiated early in ED visit.
- Where
- Canada
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Febrile Illness Acute, Biomarkers
Clinical Aspects, Management and Surveillance of Febrile Illnesses in DRC
The epidemiology and outcome of febrile illnesses in the Democratic Republic of Congo (DRC) is poorly documented. The FIKI² study, a prospective observational study of community-acquired febrile illnesses coordinated by ITM and…
- Conditions
- Febrile Illness Acute, Biomarkers, Surveillance
- Trial name
- FI-CARE (NCT07345286)
- Where
- Democratic Republic of the Congo
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Institute of Tropical Medicine, Belgium
Mothers
The Effect of Salutogenic Model-Based Care on Mothers of Children Suffering From Febrile Illness
This study was designed as an experimental study with pre-test-post-test comparisons and control groups, in order to investigate the effects of salutogenic model-based care on the individual integrity and coping attitudes of…
- Trial name
- NCT07265401
- Testing
- Salutogenic Care Model Training Program
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa