Clinical trials: Female Contraception
Contraception
A Multicenter, Open-Label, Non-Comparative Study of the Safety and Contraceptive Efficacy of the Woman's Condom
WHAT IS THE FEMALE CONDOM? The female condom being examined in this study is investigational (experimental) and is not yet approved by the Food and Drug Administration (FDA).
- Trial name
- NCT01223313
- Testing
- Woman's Condom
- Where
- 10 sites in United States
- Volunteers
- 511 people, healthy volunteers welcome
- Sponsor
- Premier Research
Contraception, Bone Metabolism
Bone Metabolism in Premenopausal Exercising Women
The main goal of this study is to examine how sex hormones and low energy availability affect the concentrations of bone remodelling markers at rest and after a running protocol.
- Conditions
- Contraception, Bone Metabolism, Low Energy Availability, Eumenorrhea
- Trial name
- BeWOMEN (NCT06961773)
- Testing
- Low energy availability, High energy availability
- Where
- Spain
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Universidad Politecnica de Madrid
Contraceptive Device; Complications
The Contraceptive Efficacy and Safety of an Intravaginal Acetic Acid Thermoreversible Gel on Chinese Women.
The study aims to explore the efficacy and safety of an intravaginal acetic acid thermoreversible gel in Chinese women of reproductive age, comparing it with nonoxinol gel by assessing the six-month Pearl Index and the incidence…
- Trial name
- contraception (NCT06203080)
- Testing
- ancetate gel, nonoxinol gel
- Where
- 4 sites in China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- National Research Institute for Family Planning, China
Contraception, Female Contraception
A Study of Efficacy and Safety With the Transdermal Contraceptive System.
The purpose of the study is to evaluate the contraceptive efficacy, safety, cycle control, and compliance with the transdermal contraceptive system.
- Trial name
- NCT00236769
- Testing
- norelgestromin + ethinyl estradiol
- Volunteers
- 1,751 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Contraception
Efficacy and Safety Study of an Oral Contraceptive in Healthy Females
The purpose of this study is to determine whether the study drug is safe and effective in the prevention of pregnancies in a large group of volunteers.
- Trial name
- NCT00206583
- Testing
- EV/DNG (Qlaira, BAY86-5027, SH T00658ID)
- Where
- 29 sites in United States, Canada
- Volunteers
- 499 people, healthy volunteers welcome
- Sponsor
- Bayer
Contraception
Effect of Norgestrel 75 mcg on Cervical Mucus and Ovarian Activity During Perfect Use, After One Delayed Intake and After a Missed Pill
Norgestrel 75 mcg is a progestin-only pill (POP), which is a kind of oral birth control pill. To be effective in preventing pregnancy, this kind of birth control pill is supposed to be taken every day at the same time, without…
- Trial name
- NCT03585712
- Testing
- Norgestrel 0.075 mg
- Where
- 2 sites in United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- HRA Pharma
Contraception
Efficacy and Safety of a Combined Oral Contraceptive of Estradiol Valerate and Dienogest in Healthy Female Subjects
To evaluate the efficacy and safety of a combined oral contraceptive of estradiol valerate and dienogest in healthy female subjects.
- Trial name
- NCT01638910
- Testing
- EV/DNG (Qlaira, BAY86-5027)
- Where
- 39 sites in China, Hong Kong and 3 more
- Volunteers
- 955 people, healthy volunteers welcome
- Sponsor
- Bayer
Contraception
Improving Reproductive Health for Women in Opioid Medication-Assisted Treatment (OMAT)
Recent research suggests that women with substance use disorders may be at a higher risk of unintended pregnancy. There is a paucity of interventions specifically focused on this population.
- Trial name
- NCT02794597
- Testing
- SHINE intervention group
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Denver Health and Hospital Authority
Sterilization, Female, Fallopian Tube Occlusion
Development of an Intrauterine Pressure Threshold to Confirm Tubal Occlusion
The overarching goal of this study is to find an alternative method to hysterosalpingogram (HSG) to confirm bilateral tubal occlusion after permanent contraception.
- Trial name
- NCT04071392
- Testing
- Hysterosalpingogram (HSG)
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Obesity
A Study to Evaluate the Effect of the Experimental GLP-1 Drug PF-07081532 on Blood Levels of Common Birth Control Pills, and Drugs Omeprazole and Midazolam, and Effect of GLP-1 Drug Semaglutide on Midazolam Blood Levels in Healthy Adults With Weight in the Obesity Range
Two different groups of healthy volunteers will be chronically treated with GLP-1 drugs PF-07081532 or alternatively Semaglutide.
- Trial name
- NCT05671653
- Testing
- PF-07081532, Semaglutide
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Pfizer
Contraception
FemBloc® Permanent Contraception - Early Pivotal Trial
Prospective, multi-center, international, non-randomized, two-arm study of subjects undergoing either FemBloc or laparoscopic bilateral tubal sterilization (Control).
- Trial name
- BLOC (NCT03433911)
- Testing
- FemBloc, Laparoscopic bilateral tubal sterilization
- Where
- 12 sites in United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Femasys Inc.
Pregnancy, Sexually Transmitted Disease
Performance and Safety Trial of an Innovative Female Condom (Wondaleaf®)
General objective: To assess the performance and safety profile of a novel innovative design of female condom (Wondaleaf®) among healthy married women.
- Trial name
- NCT02593214
- Testing
- Wondaleaf®
- Where
- Malaysia
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Clinical Research Centre, Malaysia
Contraception
Study to Investigate Efficacy and Safety of a New Oral Contraceptive
The purpose of this study is to evaluate the safety and effectiveness of a new 4-phasic preparation in the prevention of pregnancies in a large group of volunteers.
- Trial name
- NCT00185289
- Testing
- EV/DNG (Qlaira, BAY86-5027, SH T00658K)
- Where
- 50 sites in Austria, Germany and 1 more
- Volunteers
- 1,392 people, healthy volunteers welcome
- Sponsor
- Bayer
Unplanned Pregnancy
Use of Motivational Interviewing to Increase Contraception Use Among Young Women
Study design: This is a 2-phase study. During the first phase, the investigators developed a contraceptive counseling intervention based on the principles of Motivational Interviewing, trained counselors, and conducted a small…
- Trial name
- MI RCT (NCT01881321)
- Testing
- Counseling Intervention
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Healthy
Psychosocial and Physiological Mechanisms in the Effect of Hormonal Contraception on the Female Sexual Desire
75 heterosexual women are asked to use 3 different types of contraception (Nuvaring, low-dose combination pill, minipill), each during 3 months.
- Trial name
- NCT00374387
- Testing
- Nuvaring, low-dose combination pill, minipill
- Where
- Belgium
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Contraception, Female Contraception
A Study to Evaluate the Efficacy and Safety of DR-102 for the Prevention of Pregnancy
This is an open-label, single treatment study. All subjects will receive 12 months of oral contraceptive therapy with DR-102. Study participants will receive physical and gynecological exams, including Pap smear.
- Trial name
- NCT01178125
- Testing
- DR-102
- Where
- 62 sites in United States, Israel
- Volunteers
- 2,858 people, healthy volunteers welcome
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Contraception, Obesity
The Effect of Body Mass Index on Etonogestrel Hormone Levels in Women Using the Single-rod Contraceptive Implant
Two-thirds of young women in the United States are overweight or obese. This excess weight may affect how their body metabolizes drugs such as different birth control methods.
- Trial name
- Eto BMI (NCT01855620)
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Columbia University
Birth Control
Prostate Specific Antigen (PSA) and Acute Failure Modes Study of the PATH Woman's Condom and FC2 Female Condom
This is a comparative, open-label two-period crossover study of up to 505 couples comparing the PATH Woman's Condom to the FC2 female condom.
- Trial name
- CONRAD-108 (NCT01178840)
- Testing
- WC then FC2, FC2 then WC
- Where
- United States
- Volunteers
- 505 people, healthy volunteers welcome
- Sponsor
- CONRAD
Contraception, Sexually Transmitted Infections
Connecting Healthy Women: Examining the Effect of an Intervention From the Effect of Being Reachable
The investigators propose to test a community-developed and targeted intervention that employs community health workers (CHWs) as aides to newly Medicaid-insured women.
- Conditions
- Contraception, Sexually Transmitted Infections, Cervical Cancer
- Trial name
- NCT02157168
- Testing
- Community health worker
- Where
- United States
- Volunteers
- 2,267 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Preterm Birth, Health Care Utilization
Testing Feasibility of Care Coordination and Motivational Interviewing for Women With a Recent Preterm Birth
This study continues an adaptation of care coordination to address the needs of women after preterm birth. This is a small single arm open trial designed to test intervention implementation and refine the intervention before…
- Conditions
- Preterm Birth, Health Care Utilization, Tobacco Use, Contraceptive Usage
- Trial name
- NCT05120843
- Testing
- Care coordination and motivational interviewing
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia