Clinical trials: Femoral Fracture
Distal Femur Fracture
Early Weight Bearing in Distal Femur Fractures
Assessment of the effect of double plating and single lateral plating on early weight bearing as a primary outcome and improving union and decreasing complications as secondary outcomes.
- Trial name
- NCT06806839
- Testing
- dual plating, single plating
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Assiut University
Hip Fractures, Gait, Unsteady
Comparison of Sliding Hip Screw to Intra Medullary Nailing in the Treatment of Intertrochanteric Hip Fracture
Shortening of the abductor lever arm is a particular concern with the SHS, and the resultant biomechanical alterations may impair gait, including decreased cadence, gait speed and increased double support time on the injured…
- Conditions
- Hip Fractures, Gait, Unsteady, Function
- Trial name
- NCT03906032
- Testing
- TFNA IM Nail, Sliding hip screw
- Where
- Ireland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital Waterford
Closed Supracondylar Fracture of Femur
Immediate Weight Bearing Versus Protected Weight Bearing in Supracondylar Distal Femur Fractures
This study is designed to examine if immediate weight bearing on a distal femur fracture fixed with a primary locking plate, either a distal condylar locking plate or a LISS (less invasive stabilization system), is safe and…
- Trial name
- WtBrFemFx (NCT03167099)
- Testing
- Full Weight Bearing
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- West Virginia University
Hemorrhage, Fracture Femur
Comparative Use of Tranexamic Acid Intravenous and Topical Application in Intertrochanteric Fractures With PFNA
An intertrochanteric (ITF) trochanteric fracture of the femur is an exclusively extra capsular fracture in which the fracture line extends from the greater trochanter to the lesser trochanter.
- Trial name
- NCT04696224
- Testing
- Tranexamic acid, Saline solution
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Universidade do Vale do Sapucai
Hip Fractures, Osteoporosis
Chinese Second Hip Fracture Evaluation
1. To Compare overall rates of second hip fractures in both genders, 2. To determine the effect of hip fracture on proximal femoral volumetric bone mineral density (vBMD), bone structure and muscle by quantitative computed…
- Trial name
- CSHFE (NCT03461237)
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Beijing Jishuitan Hospital
Hip Fractures, Acetabular Fracture
Static Balance Disorders in Patients After Surgical Treatment of Hip Acetabular Fractures
The mechanism of maintaining balance is a complex phenomenon, involving numerous systems of human body. High-energy trauma resulting in acetabular fracture damages some of the elements composing this delicate mechanism…
- Conditions
- Hip Fractures, Acetabular Fracture, Balance; Distorted, Disability Physical
- Trial name
- NCT04902209
- Testing
- postural stability measurements
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Józef Piłsudski University of Physical Education
Pseudoarthrosis of Bone, Implant Breakage
Corticalisation After Femoral Nail Dynamization in Hypertrophic Non-unions
In 12 patients with corticalization and hypertrophic pseudarthrosis were present after dynamization, the old nail was removed and nail exchange was performed with a longer and larger diameter nail to pass the region formed in the…
- Trial name
- NCT05423561
- Testing
- exchange nailing with larger, thicker nail crossing corticalization
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Proximal Femoral Fractures
Antibiotic-Loaded Cement Versus Non-Antibiotic-Loaded Cement in Hip Prosthesis Surgery for Proximal Femur Fractures
The study aims to determine if antibiotic-loaded cement reduces post-surgery infection rates compared to non-antibiotic cement. The trial involves 450 elderly patients with specific hip fractures, assessing infection incidence…
- Trial name
- NCT06200402
- Testing
- Antibiotic loaded
- Where
- Italy
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Università Vita-Salute San Raffaele
Myocardial Injury After Non-cardiac Surgery, Hypotension During Surgery
The Effects of General Versus Spinal Anesthesia on Postoperative Myocardial Injury
In this prospective, randomized, single-blind study, we aim to compare the effects of general anesthesia and spinal anesthesia on postoperative myocardial injury in elderly patients undergoing hip surgery.
- Conditions
- Myocardial Injury After Non-cardiac Surgery, Hypotension During Surgery, Anesthesia, General, Anesthesia, Spinal
- Trial name
- NCT06343259
- Testing
- General Anesthesia, Spinal Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Pertrochanteric Fracture, Intertrochanteric Fractures
Pertrochanteric Fracture Fixation In Elderly Adults Using Proximal Femoral Nail Anti-rotation (HERACLES) With a T-shaped Parallel Blade: A New Design
This is a prospective case series of elderly adult patients sustaining pertrochanteric fractures who will be treated by a proximal femoral nail with a non-helical (straight) blade.
- Conditions
- Pertrochanteric Fracture, Intertrochanteric Fractures, Pertrochanteric Fracture of Femur, Closed, Pertrochanteric Fracture of Femur, Open
- Trial name
- Heracles PFN (NCT03911180)
- Testing
- Proximal femoral nail with straight parallel blade
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ilocos Training and Regional Medical Center
Hip Fractures
Dietary Patterns and Hip Fracture Risk in the UK Biobank
Hip fracture is a common serious injury in older adults that reduces mobility, independence, and quality of life, and can lead to premature death.
- Trial name
- NCT05554549
- Testing
- Dietary pattern observed
- Where
- United Kingdom
- Volunteers
- 500,000 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Coronary Heart Disease, Stroke
Examining the Long-Term Risks of Oophorectomy
At the time of hysterectomy for benign disease, the overall health benefits of preserving ovarian function in a large population of women have not been established.
- Conditions
- Coronary Heart Disease, Stroke, Breast Cancer, Ovarian Cancer
- Trial name
- NCT00655447
- Where
- United States
- Volunteers
- 32,175 people, healthy volunteers welcome
- Sponsor
- Parker, William H., M.D.
Post Operative Pain
Dexamethasone or Dexmedetomidine as Adjunct in Fascia Iliaca Block During Positioning for Sub-arachnoid Block & Post-operative Analgesia After Femur Neck Fracture Surgery: A Randomized Control Trial
Femur fracture is a common injury occurring in the young due to trauma as well as amongst the elderly due to fall. Reduction and fixation of femur fractures pose a challenge to the anesthesiologist.
- Trial name
- NCT05484648
- Testing
- Dexamethasone, Dexmedetomidine
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aga Khan University Hospital, Pakistan
Hip Fractures (i.e. Femoral Neck or Intertrochanteric Hip Fractures)
Impact of Fascia Iliaca Block in Hip Fracture Patients
The study is a prospective randomized examining the impact of fascia iliaca block on perioperative pain control and post operative ambulation in patients with hip fractures.
- Trial name
- NCT03525977
- Testing
- Fascia iliaca block arm
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center, El Paso
Femoral Neck Fractures
Open vs Closed Reduction in Femoral Neck Fractures Using Anterolateral vs Direct Lateral Approach
Outcomes of open vs closed reduction if emoral neck fractures
- Trial name
- FNFs (NCT07299370)
- Testing
- Closed reduction of femoral neck fractures, Open reduction of femoral neck fractures
- Where
- Egypt
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Samer youssef mansour meglaa
Femur Neck Fracture, Arthroplasty Complications
Metal Ion Levels in Total Hip Arthroplasty (THA) With Modular Dual Mobility Cup Compared to Conventional THA
After total hip arthroplasty using an 'Modular Dual Mobility' acetabular cup, which is effective in reducing the risk of dislocation, one of the serious complications occurring after total hip arthroplasty, the blood metal ion…
- Trial name
- NCT05181566
- Testing
- Total hip replacement arthroplasty using modular dual mobility cup, Total hip replacement arthroplasty using conventional acetabular cup
- Where
- South Korea
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Korea University Guro Hospital
Hip Fractures, Family
Caregivers' eCourse for Recovery After Hip Fracture
In this two part study, we will seek 1. general feedback on the feasibility of an online education and skill development program for family/caregivers of older adults recovering from a surgically repaired low-trauma hip fracture.
- Trial name
- NCT03814928
- Testing
- Caregivers eCourse
- Where
- Canada
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Osteoporosis, Achlorhydria
Does Omeprazole Decrease Intestinal Calcium Absorption?
The purpose of this study is to measure the effect of omeprazole on intestinal calcium absorption in postmenopausal women.
- Conditions
- Osteoporosis, Achlorhydria, GERD, Hip Fracture
- Trial name
- NCT00582972
- Testing
- Omeprazole
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Femur Fracture
Effect of Preoperative Carbohydrate Loading in Femur Fracture
Femur fracture is very common in older people. It makes the people bedridden for long time at hospital. The fracture of femur is generally managed by the surgical procedure.
- Trial name
- NCT04838366
- Testing
- Carbohydrate loading
- Where
- Nepal
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Armed Police Force Hospital, Nepal
Healthy, Osteopenia
Clinical Study to Estimate Bone Mineral Density With the POROUS Ultrasound Device
Osteoporosis is a widespread medical condition among older people. It causes the bones to weaken and become more likely to break.
- Conditions
- Healthy, Osteopenia, Osteoporosis
- Trial name
- POROUS-BMD (NCT07187518)
- Testing
- Measurements with the POROUS R4C ultrasound device at the midshaft tibia, DXA measurement of the hip and lumbar spine
- Where
- 2 sites in Germany
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- POROUS GmbH