Clinical trials: Ferritin, open to volunteers
Iron Deficiency
Improving Iron Levels in Female Endurance, Intermittent, and Power/Strength Athletes Aged 16-35
The goal of this clinical trial is to learn if different types and doses of oral iron supplements can improve iron levels, athletic performance, and gut health in young female athletes with low iron stores.
- Trial name
- FeSc2 (NCT06942208)
- Testing
- Low-dose iron (ferrous sulfate), Yeast-bound iron (ferrous sulfate), High-dose iron (ferrous sulfate)
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Non-Anemic Iron Deficiency
Risk of Anemia and Effects of Oral Iron Therapy in Non-Anemic Iron-Deficient Women (18-55 Years)
This study investigates the risk of anemia development in women aged 18-55 years with non-anemic iron deficiency and evaluates the clinical effects of oral iron therapy.
- Trial name
- NAID-F (NCT07263529)
- Testing
- Dietary Intervention (2 months), Oral Elemental Iron (Ferrous Sulfate) 80 mg/day
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University - Cerrahpasa
Immune-related Adverse Event, Malignant Solid Tumors
The Effect of Serum Ferritin in irAE
This is a prospective clinical study to clarify serum ferritin as a biomarker for the diagnosis, differential diagnosis and prognosis of immune-related adverse event(irAE).
- Conditions
- Immune-related Adverse Event, Malignant Solid Tumors, Acute Leukemia, Serum Ferritin
- Trial name
- NCT06702566
- Testing
- PD-1 and PD-L1 inhibitor, Targeted drugs, chemotherapy drugs
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Acute Myeloid Leukemia, Non-M3 Acute Myeloid Leukemia
Prognostic Value of CAR, AFR and Ferritin in Non-M3 AML
This prospective cohort study aims to evaluate the prognostic significance of the C-reactive protein-to-albumin ratio (CAR), albumin-to-fibrinogen ratio (AFR), and serum ferritin level in newly diagnosed de novo non-M3 acute…
- Conditions
- Acute Myeloid Leukemia, Non-M3 Acute Myeloid Leukemia, De Novo Acute Myeloid Leukemia With Multilineage Dysplasia
- Trial name
- NCT07810829
- Volunteers
- 208 people
- Sponsor
- Assiut University
Diabetic Ketoacidosis
Serum Ferritin and Prognosis of DKA
the aim of this study is to: evaluate the association between serum ferritin levels and the clinical presentation and short-term prognosis of patients with DKA.
- Trial name
- NCT06748365
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Gastric Cancer, Molecular Imaging
Novel Humanized Ferritin-based NIR Fluorescent Molecular Probe for Identifying Tumor Margins in Gastric Tissue
Radical surgery remains the primary treatment for gastric cancer, but intraoperative tumor margin assessment relies on surgeons' visual inspection, limiting accuracy.
- Trial name
- NCT07276854
- Testing
- Diagnostic Test: ICG-FTn perfusion solution
- Where
- China
- Volunteers
- 32 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Iron Deficiencies, Low Ferritin
A Pilot Study to Evaluate the Ability of Lactoferrin to Modulate Iron Homeostasis and Exercise Performance in Exercising Females
This randomized, double-blind, active-controlled trial will evaluate the effects of human lactoferrin supplementation combined with low-dose iron on iron status, aerobic performance, and lactate metabolism in exercising women…
- Conditions
- Iron Deficiencies, Low Ferritin, Iron Deficiency, Exercise Performance of Fit Athletes
- Trial name
- EFF (NCT07546591)
- Testing
- Lactoferrin 100 mg, Lactoferrin 300 mg, Iron Supplementation (5 mg)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Lindenwood University
Iron-deficiency Anemia (IDA), Hemoglobin
Comparison of Ferrous Salt vs. Liposomal Iron in Adult Women With Iron-Deficiency Anemia
The goal of this study is to compare ferrous salt and liposomal iron for the treatment of iron-deficiency anemia in adult women. The study will also evaluate how well each treatment is tolerated.
- Conditions
- Iron-deficiency Anemia (IDA), Hemoglobin, Iron Deficiencies, Adverse Effect
- Trial name
- IDA (NCT07556731)
- Testing
- Oral ferrous fumarate administered every 24 hours, Ferrous fumarate administered orally every 48 hours., Liposomal iron formulation.
- Where
- Mexico
- Volunteers
- 100 people
- Sponsor
- Hospital General de Mexico
Type 2 Diabetes Mellitus, Cardiovascular Diseases
Soluble TREM-1 in Diabetes-Associated Cardiovascular Complications
Cardiovascular disease is the leading cause of illness and death among individuals with type 2 diabetes mellitus (T2DM). Chronic low-grade inflammation contributes significantly to blood vessel damage, atherosclerosis, and…
- Conditions
- Type 2 Diabetes Mellitus, Cardiovascular Diseases, Coronary Artery Disease, Heart Failure
- Trial name
- NCT07847112
- Volunteers
- 85 people
- Sponsor
- Assiut University
Iron Deficiency Without Anemia
Assessing the Immediate Increase in Serum Ferritin After Oral Iron Doses: an Experimental Study in Iron-deficient Women
Serum ferritin is a key indicator of body iron stores and is widely used in monitoring iron status. However, oral iron doses can acutely elevate SF levels, potentially biasing assessments of iron stores during supplementation.
- Trial name
- INFER 2 (NCT06851130)
- Testing
- ferrous sulfate 80 mg, ferrous sulfate 160 mg
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- Swiss Federal Institute of Technology
Iron Deficiency Anemia of Pregnancy
Adiposity and Iron Requirements in Pregnancy
This study aims to explore how body fat influences the response to either 25 or 50 mg of daily iron supplements during pregnancy.
- Trial name
- ADIPREG (NCT06425796)
- Testing
- Adiposity and Iron Requirements in Pregnancy (ADIPREG)
- Where
- 3 sites in United Kingdom
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Iron Deficiency Anemia
Donor Breast Milk 2
The goal of this clinical trial is to determine the serum ferritin level and hematocrit level in very preterm infants receiving donor breast milk(DBM) with an early iron supplementation protocol .
- Trial name
- NCT07816601
- Testing
- Ferrous Sulfate Oral Product
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- AdventHealth
Lupus Erythematosus, Systemic
Association of Inflammatory Biomarkers and Ferritin With Severity of Pediatric Systemic Lupus Erythematosus Patients
The goal of this observational study is to learn about the association of inflammatory biomarkers (SII, NLR, and PLR) and ferritin with disease severity in pediatric systemic lupus erythematosus (pSLE) patients.
- Trial name
- NCT07901634
- Volunteers
- 62 people
- Sponsor
- Desy Wulandari
EBV, Epstein-Barr Virus Infection
Epstein-Barr Virus (EBV) gH/gL/gp42-Ferritin Nanoparticle Vaccine With or Without gp350-Ferritin in Healthy Adults With or Without EBV Infection
Background: Epstein-Barr virus (EBV) is the primary cause of infectious mononucleosis, commonly known as mono. EBV infects more than 90% of the world s population.
- Conditions
- EBV, Epstein-Barr Virus Infection, Infectious Mononucleosis, Mono
- Trial name
- NCT06908096
- Testing
- EBV gp350-ferritin vaccine with ALFQ adjuvant, EBV gH/gL/gp42-ferritin nanoparticle vaccine with ALFQ adjuvant
- Where
- United States
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Critical Illness, Sepsis
Hyperinflammation and Hyperferritinemia in Critically Ill Patients
Analysing trajectory of critically ill patients with signs of hyperinflammation
- Conditions
- Critical Illness, Sepsis, Hyperferritinemia, Hyperinflammatory Syndrome
- Trial name
- HYFER (NCT06820905)
- Where
- Czechia
- Volunteers
- 1,962 people
- Sponsor
- Charles University, Czech Republic
Iron Deficiency, Latent Iron Deficiency
Reticulocyte Hemoglobin Equivalent (RET-He) in Early Detection of Iron Deficiency Among Blood Donors and Its Potential Impact on Donor Eligibility and Transfusion Safety
Blood donation is essential for healthcare, but repeated whole-blood donation can deplete the body's iron stores. Standard pre-donation screening relies on hemoglobin levels to ensure donor safety; however, a drop in hemoglobin…
- Conditions
- Iron Deficiency, Latent Iron Deficiency, Blood Donors, Iron Deficiency Anemia
- Trial name
- NCT07861607
- Volunteers
- 300 people
- Sponsor
- Assiut University
Iron Deficiency Anemia in Pregnancy
Comparing Two Intravenous Iron Treatments for Anemia in Kurdish Pregnant Women
The goal of this clinical trial is to compare two types of intravenous (IV) iron-Ferric Carboxymaltose (FCM) and Iron Sucrose (IS)-to learn which one works better to treat iron deficiency anemia in pregnant women who have a clear…
- Trial name
- NCT07721519
- Testing
- Intravenous Ferric Carboxymaltose (FCM), Iron Sucrose (IS) Infusion
- Volunteers
- 400 people
- Sponsor
- Hawler Medical University
Still's Disease, Adult-Onset, Sepsis
Glycosylated Ferritin in Macrophagic Activation Syndromes
In healthy subjects, from 50 to 80 % of the serum ferritin is glycosylated [1, 2] . A decrease in the percentage of ferritin glycosylation can be observed in inflammatory diseases, malignancies, infections, or liver disease but…
- Conditions
- Still's Disease, Adult-Onset, Sepsis, Macrophagic Activation Syndrome
- Trial name
- FERRITGLY01 (NCT02143986)
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- Brugmann University Hospital
Iron Deficiency
Effects of Iron Supplementation on Skeletal Muscle Properties in Females With Suboptimal Iron Storage
The goal of this clinical trial is to learn whether oral iron supplementation will increase skeletal muscle iron storage and its effects on exercise capacity in females with suboptimal iron status.
- Trial name
- MyoIRON (NCT07084298)
- Testing
- Oral iron supplement
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Fatigue, Acute Illness
Cohort of Repeat Donor Experiences (CORE) Study
The Plasma Protein Therapeutics Association (PPTA) sponsors the Cohort of Repeat Donor Experiences (CORE) Study. This is a prospective, observational cohort study that will follow Source Plasma donors for up to 2 years during the…
- Conditions
- Fatigue, Acute Illness, Self-rated Health, Health Effects (Ferritin Levels, CRP Levels, iGg Levels)
- Trial name
- CORE (NCT07543965)
- Testing
- Plasmapheresis Procedure
- Where
- 12 sites in United States
- Volunteers
- 2,400 people
- Sponsor
- Westat