Clinical trials: Fertility Issues
Childhood Cancer, Fertility Issues
Addressing Fertility Information Needs and Distress
The purpose of this study is to develop and refine a behavioral intervention to address fertility-related information needs and fertility-related distress among female adult survivors of childhood cancer.
- Trial name
- NCT06834945
- Testing
- AYA SPARK
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Duke University
Fertility Issues
Lifestyle Care for Fertility Outcome Evaluation
An observational outcome evaluation of the Lifestyle Care for Fertility program.
- Trial name
- PROWESS (NCT06297070)
- Testing
- Whole Health Lifestyle Care for Reproductive Well-being pilot program
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Christine Kaiser, LAc, DACM
Fertility Issues
Continuous Double Ovarian Stimulation.
To evaluate the efficacy of the weekly use of corifollitropin alfa in double ovarian stimulation process and to compare it to the conventional protocol with daily medication administration.
- Trial name
- NCT05815719
- Testing
- Corifollitropin Alfa, Follitropin Alfa, Follitropin Alfa Biosimilar
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Instituto Bernabeu
Anti-Müllerian Hormone, Polycystic Ovarian Syndrome
Clinical Application of Serum Anti-Müllerian Hormone (AMH) Measurements
This study aims to assess the association of Anti-Müllerian hormone (AMH) with polycystic ovarian syndrome, premature ovarian insufficiency and fertility. The main objectives include the following: 1.
- Conditions
- Anti-Müllerian Hormone, Polycystic Ovarian Syndrome, Premature Ovarian Insufficiency, Fertility Issues
- Trial name
- NCT05858307
- Where
- Hong Kong
- Volunteers
- 300 people
- Sponsor
- Chinese University of Hong Kong
Fertility Issues, Stress, Psychological
Effects of Trying to Conceive Using an Home- or Hospital-based Ovulation Monitoring on Stress
The goal of this observational study is to compare the difference of stress level and anxiety and depression between couples under home ovulation monitoring and hospital ultrasound monitoring.And whether it has a negative effect…
- Trial name
- NCT06127875
- Where
- China
- Volunteers
- 311 people, healthy volunteers welcome
- Sponsor
- The First Hospital of Jilin University
Fertility Issues
PLR and NLR as Predictor Factors for Semen Abnormality
The aim of this study was to evaluate the relationship of seminal parameters with the neutrophil-to-lymphocyte ratio (NLR) and the platelet-to-lymphocyte ratio (PLR), which are inflammatory markers, in men with an abnormal semen…
- Trial name
- NCT06478199
- Testing
- semen analysis
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Ovarian Function Insufficiency, Fertility Issues
Impact of FSH Dosage During Ovarian Stimulation for IVF/ICSI in Granulosa Cells
To study the influence of different daily rec-FSH dosages (150 IU versus 300 IU), performed in the same patient in consecutive cycles, on the relation between FSH- and LH-receptors of the granulosa cells of the growing follicle.
- Conditions
- Ovarian Function Insufficiency, Fertility Issues, Infertility,Female, Infertility
- Trial name
- NCT05330130
- Testing
- Follitropin beta injection 150 IU, Follitropin beta injection 300 IU
- Where
- United Arab Emirates
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Atypical Endometrial Hyperplasia, Obese
Liraglutide Plus Megestrol Acetate in Endometrial Atypical Hyperplasia
To investigate the efficacy of liraglutide plus megestrol acetate in obesity patients with atypical endometrial hyperplasia (AEH)
- Conditions
- Atypical Endometrial Hyperplasia, Obese, Fertility Issues
- Trial name
- NCT04683237
- Testing
- Liraglutide Injection, Megestrol Acetate 160 MG
- Sponsor
- Xiaojun Chen
Transgender, Gender Incongruence
The Effect of Tucking on Semen Quality of Adult Trans Women
Because gender-affirming hormone therapy (GAHT) can lead to fertility impairment, current guidelines and treatment recommendations require that patients be informed about the possibility of fertility preservation prior to…
- Conditions
- Transgender, Gender Incongruence, Fertility Issues
- Trial name
- NCT06530992
- Testing
- tucking break
- Where
- Austria
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medical University Innsbruck
IVF, Fertility Issues
Comparison of Progestin Primed Ovarian Stimulation (PPOS) vs.GnRH Antagonist Methods on IVF Outcomes
The goal of this randomized clinical trial is to compare the effects of two different ovarian stimulation methods: Progestin Primed Ovarian Stimulation (PPOS) vs. GnRH Antagonist in embryologic outcomes of IVF Patients.
- Conditions
- IVF, Fertility Issues, Infertility
- Trial name
- NCT06396390
- Testing
- Progestin, GnRH antagonist
- Where
- Turkey (Türkiye)
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Nesta Clinic
Fertility Issues
Correlation of Urinary and Serum Hormone Levels in Natural Cycle Frozen Embryo Transfer Cycles
To evaluate whether the measurement of urinary estrone glucuronide and luteinizing hormone (LH) concentrations with an at-home device is correlated with serum hormone levels within a natural cycle frozen embryo transfer protocol.
- Trial name
- MIRA (NCT06410170)
- Testing
- MIRA Device
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ottawa Fertility Centre
Hysteroscopy, Hysteroscopy Technique
UTERINE EVALUATION FOR THE IDENTIFICATION OF PATHOLOGY. This Study Will Compare the Intrauterine Pathology Detection Rate Between Standard of Care Hydrosonography, and a New Visual Saline Infusion Device Providing Direct Visualization of the Uterus.
This is a prospective, single center, multiple arm cohort study intended to compare the diagnostic accuracy of a Visual Saline Infusion Device (VSI) device, vs standard of care Hydrosonography in reproductive aged women to…
- Conditions
- Hysteroscopy, Hysteroscopy Technique, Fertility Issues, Uterus Abnormal
- Trial name
- NCT06394752
- Testing
- Visual Saline Infusion, Hydrosonography
- Where
- 2 sites in United States, Mexico
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Center for Reproductive Health & Gynecology
Fertility Issues
Assisted Reproductive Techniques (ART) With Sperm Donation : an Inclusive Model of ART for All Women
This is a monocentric, retrospective, non-interventional study. The main objective is to describe the populations requesting assisted reproductive techniques (ART) with sperm donation ; and compare them between groups depending…
- Trial name
- PMAPT (NCT06163079)
- Testing
- No intervention
- Where
- France
- Volunteers
- 675 people
- Sponsor
- Central Hospital, Nancy, France
Fertility Issues, Cancer
Fertility Preservation and Pregnancy and Offspring Health Outcomes in Female Cancer
To explore whether there is a significant difference in the cumulative live birth rate and maternal and child health outcomes between cancer patients who undergo or do not undergo fertility preservation before receiving…
- Trial name
- NCT06360471
- Testing
- fertility preservation
- Where
- China
- Volunteers
- 2,800 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Fertility Issues
The Effectiveness of Advanced Decision Support Tool (OPT-IVF) for IVF Treatment
This prospective study is subject to approval of institutional medical research ethics committee. Patient undergoing second cycle IVF will be enrolled into the intervention group.
- Trial name
- NCT06179420
- Testing
- total cumulative gonadotrophin usage
- Where
- Malaysia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Fertility Issues
Survival and Reproductive Outcomes of Malignant Ovarian Germ Cell Tumors
Malignant ovarian germ cell tumor patients conducted fertility-sparing surgery and adjuvant chemotherapy in Kasr El-Aini Hospital - Faculty of Medicine - Cairo University from January 2012 to December 2016 will be retrospectively…
- Trial name
- NCT05905289
- Testing
- observational study
- Where
- Egypt
- Volunteers
- 27 people
- Sponsor
- Cairo University
Transgenderism, Fertility Issues
Transgender Caregivers' and Patients' Representations of Parenthood as Part of a Fertility Preservation Pathway
This research aims to understand the impact of fertility preservation consultation on transgender patients' projection and how the possibility of preserving gametes influences transgender people's transition paths, parenthood…
- Trial name
- TransFert (NCT06218446)
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Fertility Issues, Disclosure
Feasibility Trial of the TELL Tool Intervention
A radical paradigm shift is taking place where technology, notably the explosion in easy accessible direct-to-consumer genetic testing (e.g., 23andMe) and a high consumer interest in genealogy (e.g., Ancestry.com), has hijacked…
- Conditions
- Fertility Issues, Disclosure, Parenting
- Trial name
- NCT04841967
- Testing
- TELL Tool Intervention, eBook Attention Control
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Chicago
Fertility Issues
Assessing the Fertility Status of Men With Spinal Muscular Atrophy (SMA)
This study will aim to assess the fertility status of men with Spinal Muscular Atrophy (SMA) not on disease-modifying therapies. Participants will: 1.
- Trial name
- NCT06194539
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Bar-Chama, Natan, M.D.
Fertility Issues
The Combination of Sperm Selection by IMSI and Hyaluronic Acid Binding Assay May Improve ICSI Outcome.
In this prospective randomized sibling-oocytes blinded study, investigators examine the combination of two sperm selection methods that logically seem to complete each other, and potentially may improve ICSI outcomes.
- Trial name
- NCT06156722
- Testing
- Sperm selection by IMSI, Sperm selection by IMSI and spermslow
- Where
- Israel
- Volunteers
- 189 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center