Clinical trials: Fetus Disorder
Hereditary Diseases
Development of New Prenatal Diagnostic Tests From Maternal Blood
After extraction of the cell-free DNA circulating in maternal plasma, we aim at developing new techniques for fetal DNA enrichment to perform fetal gender determination, and indirect diagnosis of inherited diseases like Cystic…
- Trial name
- NCT00314691
- Testing
- Blood samples
- Where
- France
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Depression
Effectiveness of Group Interpersonal Psychotherapy in Treating Women With Prenatal Depression
This study will evaluate the effectiveness of group interpersonal psychotherapy for preventing postpartum depression in pregnant women with depression and for improving healthy outcomes in their babies.
- Trial name
- NCT00633178
- Testing
- Group interpersonal therapy (IPT), Treatment as usual (TAU)
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Pregnancy, Helicobacter Pylori Infection
Effects of Dietary Heme/Non-heme Iron and Helicobacter Pylori (Hp) Infection on Maternal Iron-deficiency Anemia and Fetal Growth Outcomes
Iron deficiency is considered one of the main nutritional deficiency disorders despite the apparent availability of a high-quality diet even in developed countries, and Iron deficiency anemia (IDA) is the most common form of…
- Conditions
- Pregnancy, Helicobacter Pylori Infection, Iron-Deficiency Anemia
- Trial name
- NCT01071759
- Where
- Taiwan
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- E-DA Hospital
Fetal Alcohol Spectrum Disorders
Improving Self Regulation in Children With Fetal Alcohol Syndrome Spectrum Disorders: A Neuroplastic Intervention
This study on children with fetal alcohol spectrum disorder (FASD) aims to (i) characterize their self-regulation deficits, a process important for controlling emotions and behavior, (ii) describe brain structure and function…
- Trial name
- NCT02457676
- Testing
- Alert Program for Self-Regulation
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Meconium Aspiration Syndrome
Interleukin-6 in the Development of Meconium Aspiration Syndrome in Newborn
This trial is intended to assess the serum levels of interleukin-6 as a predictive factor for the occurrence of meconium aspiration syndrome in infants born with MSAF.
- Trial name
- NCT07394322
- Testing
- serum interleukin 6
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Benha University
Fetal Weight, Obesity, Morbid
Comparison of Three Methods for Fetal Weight Estimation
The aim of this study was to compare maternal, clinical and ultrasound estimations of fetal weight in women with severe (BMI>35) and morbid (BMI>40) obesity and to determine the effect of maternal body mass index (BMI) on these…
- Conditions
- Fetal Weight, Obesity, Morbid, Pregnancy Related
- Trial name
- NCT05478798
- Testing
- ultrasonographic fetal weight estimation, clinical fetal weight estimation, maternal subjective fetal weight estimation
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Prenatal Care
Group Antenatal Care: The Power of Peers for Increasing Skilled Birth Attendance in Achham, Nepal
In rural Nepal, the major drivers of underutilization of skilled birth attendance are poverty, poor social support and inadequate birth planning.
- Trial name
- NCT02330887
- Testing
- Group Antenatal Care, Individual Antenatal Care
- Where
- Nepal
- Volunteers
- 2,184 people, healthy volunteers welcome
- Sponsor
- Possible
External Causes of Morbidity and Mortality, Stillbirth
Linking Facility-based Mortality Audits With Community Engagement in Gilgit-Baltistan, Pakistan
Pakistan is one of the countries in South Asia where neonatal mortality rates remain stagnant. Babies born in Pakistan encounter the highest risk of dying; of every 1,000 babies born, 46 die before the end of their first month…
- Conditions
- External Causes of Morbidity and Mortality, Stillbirth, Neonatal Death
- Trial name
- NCT03904706
- Testing
- Audits only, Audits with community feedback
- Where
- Pakistan
- Volunteers
- 1,871 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Maternal Distress in Labor, Persistent Occipitoposterior or Occipitoanterior Position
Maternal Positioning and Occipitoposterior Fetal Position
The aim of the study is to evaluate the efficacy of a specific maternal position to correct fetal position in occipito-posterior during the labor.
- Conditions
- Maternal Distress in Labor, Persistent Occipitoposterior or Occipitoanterior Position, Dystocia, Fetal Position and Presentation Abnormalities
- Trial name
- NCT01291355
- Testing
- Specific maternal position during the labor
- Where
- 2 sites in Switzerland
- Volunteers
- 438 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Inflammation, Obesity
Omega-3 Supplementation Decreases Inflammation and Fetal Obesity in Pregnancy
Randomized, double-blind placebo controlled trial of fish oil to decrease inflammation in pregnancy.
- Conditions
- Inflammation, Obesity, Pregnancy, Fetal Growth
- Trial name
- NCT00957476
- Testing
- Omega-3 Fish Oil
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- MetroHealth Medical Center
Prenatal Anxiety, Prenatal Attachment
The Effects of Angel Sounds and Guided Imagery Technique Played to Expectant Couples
The study sample consisted of 177 pregnant women and their partners who met the inclusion criteria and participated in a prenatal education class.
- Conditions
- Prenatal Anxiety, Prenatal Attachment, Sleep Quality
- Trial name
- NCT05441033
- Testing
- Fetal Heart Sounds (FHS) Listening Intervention, Guided Imagery Technique (GIT) Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 354 people, healthy volunteers welcome
- Sponsor
- Inonu University
Alcoholism, Pregnancy
Prevention of Fetal Alcohol Spectrum Disorder (FASD) by the Use of Technology
The Institute of Health Economics is conducting a study to determine how a breathalyzer linked to a cloud based alcohol monitoring system changes alcohol consumption during pregnancy in women with alcohol dependency issues.
- Trial name
- NCT02759874
- Testing
- specialized breathalyzer w face recognition technology
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Institute of Health Economics, Canada
Monogenic Diseases
NIPD of CFTC by WGA Coupled to Mini-exome Sequencing
The purprose of this study is to develop a single test based on circulating fetal trophoblastic cells (CFTC) analysis from maternal blood, searching for the familial mutation for a wide range of monogenic diseases.
- Trial name
- DIAFEXOME (NCT03743948)
- Testing
- Non invasive prenatal diagnosis
- Where
- France
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Fetal Anomaly
Validation of a Test for Fetal Malformations
The investigators have developed a diagnostic test for the evaluation of the presence of fetal malformations through metabolomic analysis of maternal peripheral blood serum by chromatographic techniques and mass spectrometry, and…
- Trial name
- NCT02965287
- Testing
- Serum metabolomics profiling
- Where
- Italy
- Volunteers
- 1,943 people, healthy volunteers welcome
- Sponsor
- Theoreo Srl
Trisomy 13, Trisomy 18
Multiple Gestation Study
The objectives of the clinical study are to demonstrate the accuracy of our new NATUS diagnostic method to determine the genetic health of the developing fetuses in a multiple gestation pregnancy from a maternal blood sample.
- Conditions
- Trisomy 13, Trisomy 18, Trisomy 21, Sex Chromosome Abnormalities
- Trial name
- NCT02278536
- Where
- 8 sites in United States, India and 1 more
- Volunteers
- 354 people, healthy volunteers welcome
- Sponsor
- Natera, Inc.
Mindfulness Breath Awareness Meditation, Preeclampsia
Mindfulness Breath Awareness Meditation and Preeclampsia
The effect of mindfulness breath awareness meditation on health profile, vital signs, and fetal heart rate in pregnant women with preeclampsia
- Trial name
- NCT06065709
- Testing
- Mindfulness breath awareness meditation
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Aysegul Kilicli
Congenital Heart Disease
Fetal Heart Ultrasound Suspicious Radiographic Finding Identification - Reader Study
Clinical performance of the device will be evaluated in a fully-crossed, multiple-reader multiple-case (MRMC) study. This study will be used to determine the impact of the device on reader performance in identifying suspicious…
- Trial name
- NCT06392555
- Testing
- Device-Aided performances, Device-Unaided performances
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- BrightHeart
Rupture of Membranes; Premature
Urea and Creatinine Level in Vaginal Fluid as a Predicator for Length of Latency Period in Prelabour Membranes Rupture
This study aims to investigate the relation between the concentration of urea and creatinine in vaginal fluid and length of latency period in women with PROM between 32 and 35 weeks gestation.
- Trial name
- NCT03213535
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
IUGR
HMGB1 Levels at Fetal Growth Restriction
The primary aim of this study is to evaluate HMGB1 levels in cases of intrauterine growth restriction (IUGR). The secondary aim is to determine whether the cerebroplacental ratio interacts with these levels.
- Trial name
- NCT07857525
- Testing
- hmgb1
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Preterm Labor (24 GA - 32 GA)
Identification of Spontaneous Delivery Markers
The investigators project aims to identify, in pregnant women, discriminating molecules to allow an early detection of women who will spontaneously deliver prematurely, suitable in routine clinical practice.
- Trial name
- TrophY2 (NCT02225717)
- Testing
- Cervicovaginal swab
- Where
- France
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris