Clinical trials: Fetus Disorder
Labor Long, Nulliparity
HIDRATA Study: Efficacy of a Hydration Protocol in Nulliparous Women During Labor
Aim. To evaluate the efficacy of optimizing hydration during labor in nulliparous women with respect to reducing the duration of dilation and the second stage of labor, lowering the incidence of Cesarean sections and fever, and…
- Conditions
- Labor Long, Nulliparity, Premature Rupture of Membrane, Pregnancy, Prolonged
- Trial name
- HYDRATA (NCT03607929)
- Testing
- optimal, variability
- Where
- Spain
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Puerta de Hierro University Hospital
Body Composition, Obesity
Fetal Programming of Immune Response and Body Fat by Maternal Obesity
According to the Chilean National Health Survey 2009-2010, 60% of woman in reproductive age are overweight or obese with detrimental consequences on women as well as offspring´s health at long term.
- Trial name
- EpiFat (NCT04249635)
- Testing
- DHA
- Where
- Chile
- Volunteers
- 247 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Rupture of Membranes; Delayed Delivery (Following Spontaneous Rupture), Rupture of Membranes; Premature
Latency Antibiotics in Previable PPROM, 18 0/7- 22 6/7 WGA
This study is a non-blinded, prospective, randomized controlled trial designed to compare the effect of outpatient oral antibiotics (i.e., amoxicillin and azithromycin) on the length of time (days) that pregnancy continues after…
- Conditions
- Rupture of Membranes; Delayed Delivery (Following Spontaneous Rupture), Rupture of Membranes; Premature, Rupture of Membranes; Premature, Affecting Fetus, Preterm Birth
- Trial name
- NCT04047849
- Testing
- Antibiotics, oral Azithromycin and oral Amoxicillin
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Woman's
Healthy
Fetal Aortic Pulsewave Velocity: A Novel Doppler Ultrasound Method of Measuring the Biophysical Properties of the Fetal Aorta
We are interested in determining if we can measure the blood flow in the descending aorta (large blood vessel in the abdomen) of healthy fetuses and fetuses with growth restriction. An increasing number of adult diseases (e.g.
- Trial name
- NCT00359034
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of British Columbia
Covid19, Maternal-Fetal Relations
Maternal And Neonatal Outcome of Pregnant Patients With COVID-19 in Istanbul, Turkey: A Single-Center, Retrospective, Descriptive Study
Evaluation of apgar, hemogram and developmental status of babies born from covid 19 positive mothers
- Trial name
- NCT04337320
- Testing
- newborns from covid 19 positive mothers
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Pregnancy, Immune System Disorder
PRINCE Study - Cohort Study of Healthy Pregnant Women Followed by the Assessment of Children´s Health and Immunity
In the PRINCE study we recruit healthy but also diseased pregnant women into a cohort study, followed by the assessment of children´s health and immunity at birth and during the first 10 years of life.
- Trial name
- PRINCE (NCT05002023)
- Where
- Germany
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Fetal Alcohol Spectrum Disorders
The Trajectory of Fetal Alcohol Spectrum Disorders (FASD) Across the Life Span: Continuing Prevention and Longitudinal Epidemiology
Screen women of childbearing age (15 - 44 years) for high risk drinking in antenatal clinics of the established research sites in the Western Cape Province of South Africa (SA).
- Trial name
- NCT04026620
- Testing
- Informational Pamphlet, Brief Motivational Enhancement Therapy (MET) Session
- Where
- South Africa
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Preeclampsia
LMWH to Prevent Preeclampsia and Fetal Growth Restriction
The objective of this trial will be to determine whether prophylactic low-molecular weight heparin therapy in pregnant women with the heterozygous Factor V Leiden and G20210A prothrombin gene mutations thrombophilia and a history…
- Trial name
- NCT00260520
- Testing
- Dalteparin
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florence
Macrosomia, Fetal, Large for Gestational Age
Fetal Clavicular Measurement to Predict Fetal Macrosomia
Macrosomia is associated with increased risks for both the mother and the baby, including complications during delivery, injuries, and even death. The accurate diagnosis of macrosomia is often difficult before birth.
- Conditions
- Macrosomia, Fetal, Large for Gestational Age, Shoulder Dystocia
- Trial name
- NCT06283277
- Testing
- Obstetric Ultrasound
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Assiut University
Pathology of Pregnancy
Maternal Plasmatic Regulatory T Cells and Th17 as Possible Diagnosis Markers of Acute Chorioamnionitis
The purpose of this study is to evaluate if regulator T cells (Treg) and Th17 level modifications in maternal blood and placenta could be correlated to a chorioamnionitis, in women hospitalized for PPROM.
- Trial name
- ICAR (NCT01610258)
- Testing
- Blood and placenta samples
- Where
- 2 sites in France
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Nephropathy
Amniotic Biomarkers for the Prediction of Postpartum Renal Function.
The discovery of antenatal bilateral renal anomaly poses an essential question: can we predict postnatal renal function? Ultrasound is insufficiently precise to predict postnatal renal function evolution.
- Trial name
- BIOMAN (NCT02675686)
- Where
- 31 sites in France
- Volunteers
- 358 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Fetal Death
Mifepristone-misoprostol vs. Misoprostol Alone for Second Trimester Fetal Death
The primary aim of this trial is to compare the efficacy of mifepristone-misoprostol versus misoprostol alone for treatment of intrauterine fetal demise between 14 and 28 weeks LMP.
- Trial name
- NCT02633761
- Testing
- Mifepristone, Misoprostol 200mcg
- Where
- 3 sites in Mexico, Vietnam
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Obesity, Lifestyle-related Condition
Lifestyle Intervention in Preparation for Pregnancy (LIPP)
Studies evaluating lifestyle intervention in obese women during pregnancy have reported limited success in decreasing excessive gestational weight gain, and have failed to achieve the key outcome of breaking the obesity cycle and…
- Conditions
- Obesity, Lifestyle-related Condition, Macrosomia, Fetal
- Trial name
- NCT03146156
- Testing
- Lifestyle Intervention
- Where
- 4 sites in United States
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Tufts Medical Center
Placenta Previa
The Placenta Previa and Fetal Weight
Placenta previa is a placenta that implants at lower uterine segment, it occurs in about 0.3-0.5% of pregnancies at term. It is a significant risk for development of maternal morbidity, as well as maternal mortality secondary to…
- Trial name
- NCT03321435
- Testing
- placenta previa patient, normal women
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Assiut University
Maternal Care Patterns, Nutrition, Healthy
The 1000 First Day of Life : Effect of Multi Micronutrients Supplementation on Pregnancy Outcomes
To monitor the effects of multi micronutrients supplementations during pregnancy towards pregnancy outcomes
- Conditions
- Maternal Care Patterns, Nutrition, Healthy, Nutritional Deficiency, Maternal-Fetal Relations
- Trial name
- NCT06035315
- Testing
- Multiple Micronutrients during pregnancy
- Where
- 2 sites in Indonesia
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Dr Cipto Mangunkusumo General Hospital
PreTerm Birth
New Tool to Predict Risk of Spontaneous Preterm Birth in Asymptomatic High-risk Women
The QUIPP tool integrates information of obstetrical history, quantitative fetal fibronectin (qfFN) and cervical length to predict the risk of sPTB in asymptomatic high-risk women.
- Trial name
- NCT03062020
- Testing
- QUIPP
- Where
- 2 sites in Spain
- Volunteers
- 258 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
Preterm Birth, Prenatal Care Late
This Study Was to Investigate the Efficacy of Fetal Right Heart Doppler Findings in Determination of Pulmonary Maturity
Objective: The aim of this study was to investigate the efficacy of fetal right heart doppler findings in determination of pulmonary maturity.
- Conditions
- Preterm Birth, Prenatal Care Late, Preterm Labor
- Trial name
- NCT04296591
- Testing
- fetal heart doppler findings
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Maternal Death, Maternal Infections Affecting Fetus or Newborn
Azithromycin-Prevention in Labor Use Study (A-PLUS)
Maternal and neonatal infections are among the most frequent causes of maternal and neonatal deaths, and current antibiotic strategies have not been effective in preventing many of these deaths.
- Conditions
- Maternal Death, Maternal Infections Affecting Fetus or Newborn, Neonatal SEPSIS, Maternal Sepsis During Labor
- Trial name
- NCT03871491
- Testing
- Azithromycin
- Where
- 8 sites in Bangladesh, Democratic Republic of the Congo and 5 more
- Volunteers
- 58,747 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Pregnancy, Pregnancy Complications
AI-POCUS for Maternal and Neonatal Health in Ethiopia
Maternal and neonatal health remains one of the most pressing global health challenges, particularly in low- and middle-income countries (LMICs).
- Conditions
- Pregnancy, Pregnancy Complications, Preterm Birth, Fetal Growth Restriction
- Trial name
- AIM-ETH (NCT07171086)
- Testing
- AI-POCUS (BabyChecker, Delft Imaging), AI-POCUS (Edan, China)
- Where
- Ethiopia
- Volunteers
- 1,059 people, healthy volunteers welcome
- Sponsor
- Tsinghua University
Preeclampsia and Intrauterine Growth Restriction
Placental Insufficiency Microcirculation Quantification by Ultrafast Doppler (MICRODOPPLER PLACENTA)
To identify fetuses small for their gestational-age who have reached their appropriate growth potential from growth-restricted fetuses due to placental insufficiency is uneasy.
- Trial name
- NCT03860103
- Where
- France
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital