Clinical trials: Fluid Balance
Fluid Balance
Effect of Adding Glycerol to Electrolyte Beverages on Fluid Balance in Healthy Euhydrated Men and Women at Rest
The results of a prior study PEP-2311 suggested there was a positive dose-response effect of glycerol and sodium on fluid balance and fluid retention.
- Trial name
- NCT06654557
- Testing
- 0% carbohydrate electrolyte solution with glycerol beverage (Part 1 only), 0% carbohydrate electrolyte solution without glycerol beverage (Part 1 only), 1% carbohydrate electrolyte solution with glycerol beverage (Parts 1 and 2)
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Aging, Dehydration
The Effect of Fluids Consumption on Balance and Gait Function in Old Adults
Experimental design overview The proposed project is a prospective experimental RCT study design. Independent old adults(age 65 years old and older) who do not suffer from balance problems willing to participate in the study will…
- Trial name
- NCT01181180
- Testing
- water consumption
- Where
- Israel
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Obstructive Sleep Apnea-hypopnea Syndrome (OSAHS)
Study of the Effect of an Elastic Compression Medical Device, on Water Balance Change in Healthy Subjects
Obstructive sleep apnea-hypopnea syndrome (OSAHS) is characterized by the occurrence of abnormally frequent episodes of interrupted ventilation (apnea) or significant reduction of ventilation (hypopnea) during sleep.
- Trial name
- NCT04911725
- Testing
- Elastic Compression Prototype
- Where
- France
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Laboratoires Innothera
Cryotherapy Effect, Balance; Disorder, Fluid
Effect on Dynamic Postural Stability After Application of Cryotherapy to the Knee Joint
The purpose of this study will determine the effect of cryotherapy applied to the knee joint on static and dynamic standing balance.
- Trial name
- NCT03151031
- Testing
- Cryotherapy
- Where
- India
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Asir John Samuel
Healthy
"Beverage Hydration Index" of Commercial Therapeutic Beverages
The "beverage hydration index" (BHI) assesses the hydration potential of any consumable fluid relative to water. The BHI is a relatively new metric.
- Trial name
- NCT03262597
- Testing
- enterade, Pedialyte, Gatorade
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Sonoma State University
Exposure to Magnetic Field, Hypotension During Dialysis
Dermal Profile Analysis Using the NMR-MOUSE
The determination of fluid status in dialysis patients is a major clinical problem. In this study the NMR-MOUSE is used to determine if it can be used to non-invasively determine hydration status of the skin.
- Conditions
- Exposure to Magnetic Field, Hypotension During Dialysis, Disturbance; Balance, Fluid
- Trial name
- SHN (NCT02934009)
- Testing
- Dermal nuclear magnetic resonance (NMR)-profile measurement
- Where
- Germany
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- RWTH Aachen University
Nutrition, Healthy Male and Female Subjects
Influence of Food Texture on Appetite Control, Gastric Emptying, and Energy Expenditure
The aim of the study is to investigate the effect of liquid versus semi-solid meals on the regulation of energy balance in healthy young adults.The main questions it aims to answer are: Does a protein-rich liquid meal result in…
- Trial name
- NCT06853249
- Testing
- liquid meal, semi-solid meal, caloric drink + semi-solid meal
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Kiel
Fluid Retention Due to Heart Failure
A Mass Balance Study of [14C]HRS-9057 for Injection in Healthy Participants
This study is a single-center, open-label, single-dose phase I clinical trial. The trial is divided into four periods: screening, baseline, treatment, and follow-up
- Trial name
- NCT07681479
- Testing
- [14C]HRS-9057
- Where
- China
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Fujian Shengdi Pharmaceutical Co., Ltd.
Fluid Retention, Fluid Loss
The Effect of AMP Human Sodium Bicarbonate Lotion on Hydration
The purpose of this research study is to evaluate the effects of a topical sodium bicarbonate lotion on physiological and psychological responses associated with hydration status and fluid balance in humans during passive heat…
- Conditions
- Fluid Retention, Fluid Loss, Sodium Retention, Cognitive Change
- Trial name
- AMPlify (NCT04598386)
- Testing
- PR Lotion - AMP Human Performance
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Dehydration
Fluid Balance During Exercise in the Heat With Water, Flavored Placebo, or a Carbohydrate-electrolyte Beverage Intake (The APEX Study)
The purpose of the APEX study is to determine whether carbohydrate-electrolyte beverage intake promotes fluid balance during exercise in the heat compared with water or placebo intake.
- Trial name
- APEX (NCT01893853)
- Testing
- Exercise Intervention
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Endometriosis Related Pain, Overactive Bladder
A Trial to Learn How a New Liquid Form of BAY1817080 is Tolerated and Taken up by the Body of Healthy Male Participants (Part A). By Labeling BAY1817080 With a Radioactive Substance (Carbon 14) Researchers Want to Learn How the Study Drug is Processed and Excreted by the Body After Dosing (Part B)
Researchers are looking for a new way to treat people suffering either from a condition where the bladder is unable to hold urine normally (overactive bladder), or a condition in which tissue similar to the tissue that normally…
- Conditions
- Endometriosis Related Pain, Overactive Bladder, Diabetic Neuropathic Pain, Refractory or Unexplained Chronic Cough
- Trial name
- NCT04487431
- Testing
- BAY1817080, [14C]BAY1817080
- Where
- Netherlands
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Bayer
Fluid Balance Outcomes
A Comparison of Three Commercial Oral Rehydration Solutions Consumed After Extra-cellular Dehydration
Dehydration is commonplace in a number of settings, including exercise, daily living (i.e. inadequate fluid intake) and with relatively common bacterial/viral infections that induce diarrhoea and/or vomiting.
- Trial name
- NCT05775055
- Testing
- Composition of oral rehydration solutions
- Where
- United Kingdom
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Hydration
Bioimpedance In Pregnancy and Labour: A Fluid Balance Concept Study.
The purpose of our study is to find out if using a simple bed side test can tell us information about changes that occur in women's body water content.
- Trial name
- BiPAL (NCT03823820)
- Testing
- Bioimpedance Analyser
- Where
- United Kingdom
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- University Hospitals, Leicester
Education, Surgical Nursing
Digital Flashcards for Fluid and Electrolyte Education in Surgical Nursing: A Solomon Four-Group Study
This study aims to investigate the effect of the digital flashcard method, compared to traditional lecturing, on students' knowledge levels and self-efficacy perceptions regarding fluid-electrolyte balance in the surgical nursing…
- Conditions
- Education, Surgical Nursing, Teaching Methods
- Trial name
- Flashcards (NCT07869459)
- Testing
- Digital Flashcard Training & Pre-test/Post-test, Digital Flashcard Training & Post-test Only, Standard Lecture Only & Pre-test/Post-test
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Rate of Water Appearance/Delivery in the Blood, Water Balance
Effects of Drink Composition on the Appearance of Ingested Water in Body Fluids
To determine the effects of amino acids on the rate of water absorption and availability as a precursor fluid for sweat. Young and healthy (male or female) volunteers will take part in three experimental trials.
- Trial name
- NCT04509388
- Testing
- Composition of Sports Drink
- Where
- United Kingdom
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Healthy Volunteers
Adaptation of Thirst to a Single Administration of Tolvaptan (TOLVATHIRST)
Tolvaptan is a new drug that specifically antagonizes the V2-receptor of antidiuretic hormone (ADH) and leads to water diuresis: During acute administration of tolvaptan, the main fear is to induce a too fast increase in plasma…
- Trial name
- TOLVATHIRST (NCT03931369)
- Testing
- Tolvaptan 15 MG
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Colonoscopy, Bowel Preparation
Acid-base Balance in Patients Undergoing Colonoscopy
The purpose of this study is to determine whether fluid administration in patients undergoing colonoscopy should affect acid-base disorder in term of the strong ion differences.
- Trial name
- NCT01250886
- Testing
- Lactated Ringer's solution, Normal saline solution, Acetate Ringer's solution
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Healthy
Determining the Effects of Training on Nursing Students Using Two Different Methods for Maintaining Fluid and Electrolyte Balance in a Child Trapped Under a Collapse
The aim of this randomized controlled trial is to determine the effects of two different training methods on nursing students regarding the maintenance of fluid and electrolyte balance in a child trapped under rubble.
- Trial name
- NCT07491757
- Testing
- Nursing Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Water Balance Disorders, Dehydration
The Jugular Vein Ultrasonography for Hydration Assessment in Healthy Participants
The aim of this cross-sectional, descriptive analysis is to compare 3 different ultrasound-based protocols to measure the internal jugular vein pressure (uJVP) in healthy individuals.
- Conditions
- Water Balance Disorders, Dehydration, Hypervolemia
- Trial name
- NCT06706960
- Testing
- measurement of IJV-height
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Postoperative Cardiorespiratory Failure
Hypertonic Saline-hetastarch in Cardiac Surgery
Cardiopulmonary bypass(CPB) is associated with increased fluid extravasation and edema formation. A continuous infusion of a mixture of hypertonic saline/hydroxyethyl starch (HSH)during CPB reduced fluid extravasation and total…
- Trial name
- HH (NCT00469716)
- Testing
- Hypertonic saline (7.2%) hetastarch (6 %)(200/0.5)
- Where
- Norway
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital