Clinical trials: Flushing
Acute Respiratory Failure
Non-rebreather at Flush Rate Compared to Bag Valve Mask With Assist
This crossover investigation enrolls healthy volunteers and compares the exhaled oxygen content (FeO2) between the non-rebreather mask at the flush rate and a bag-valve-mask device at the flush rate, used with active positive…
- Trial name
- NCT02841592
- Testing
- Flush rate oxygen, Flush rate oxygen with assist
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Hennepin Healthcare Research Institute
Hot Flashes
Safety and Efficacy of Dr. Tagliaferri's Menopause Formula
The primary goal of this study is to evaluate the safety and efficacy of 12 weeks of treatment of 4 grams/day of Dr. Tagliaferri's Menopause Formula (administered as 2 grams PO BID) in reducing the frequency of menopausal…
- Trial name
- NCT01957306
- Testing
- Dr. Tagliaferri's Menopause Formula
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Herba Buena, Inc
Psychotic Disorders, Schizophrenia
The Topical Niacin Skin Flush Test in First Episode Psychosis
The purpose of this study is to gather normative data from healthy adults and to determine a sensitive and specific cut-off value for responders and non-responders to the Niacin Skin Flush Test in a sample of first episode…
- Trial name
- NCT01324297
- Testing
- skin test
- Where
- Canada
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Breast Cancer, Hot Flashes
Effect of Non-estrogenic Pollen Extract PCC-100 on Hot Flushes
Many postmenopausal women have vasomotor symptoms during adjuvant hormonal treatment for breast cancer. PCC-100 is a pollen extract used for alleviation of postmenopausal symptoms.
- Conditions
- Breast Cancer, Hot Flashes, Postmenopausal Symptoms
- Trial name
- NCT03684096
- Testing
- non-estrogenic pollen extract PCC-100
- Where
- Belgium
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Follicular Fluid, Granulosa Cell
Intrauterine Flushing With Follicular Fluid Plus Granulosa Cells
One hundred forty patients with male factor infertility are randomized into two groups. In the study group, flushing the endometrial cavity with 2ml of clear follicular fluid with granulose cells will be performed using an IUI…
- Conditions
- Follicular Fluid, Granulosa Cell, Embryo Implantation
- Trial name
- NCT04077970
- Testing
- Intrauterine flushing of follicular fluid with granulosa cells
- Where
- Iran
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Royan Institute
Menopause, Menopause Related Conditions
Hot Water Therapy for the Treatment of Menopause-related Hot Flashes
The purpose of this research is to determine whether hot water therapy (i.e. taking prolonged hot baths on multiple consecutive days) decreases hot flash symptoms and improves mood in women who are undergoing or who have…
- Conditions
- Menopause, Menopause Related Conditions, Menopause Syndrome
- Trial name
- NCT06192329
- Testing
- Hot water therapy, Warm water immersion
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Colorado, Colorado Springs
Clinical Pregnancy
Endometrial Follicular Fluid Flushing and IVF Outcome
Objective: In this study, our aim will be investigating the pregnancy results in unexplained infertile women undergoing ICSI, by flushing the endometrial cavity with folliculer fluid, that we maintain mature follicules inside…
- Trial name
- NCT04479059
- Testing
- follicular fluid flushing
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Zeynep Kamil Maternity and Pediatric Research and Training Hospital
Postmenopausal Symptoms, Hot Flashes
WHAT (Women, Hot-flashes, Activity, Trial) - Physical Activity for Treatment of Hot Flushes Among Postmenopausal Women
More than 60 % of women experience hot-flashes during postmenopausal and 20 % have serious symptoms. Use of combined estrogen/progesterone therapy reduces hot-flashes effectively.
- Trial name
- WHAT (NCT01282320)
- Testing
- Physical activity intervention program
- Where
- Norway
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital of North Norway
Healthy
Nicotinic Acid - Pharmacokinetics, Pharmacodynamics, Receptor Expression
The study will be a double-blind, randomized, placebo-controlled, single-center, 2 treatment, 3--way crossover. Subjects will be randomly allocated to a treatment sequence - AAB, ABA or BAA.
- Trial name
- NCT00176020
- Testing
- nicotinic acid
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Heidelberg University
Hot Flashes, Menopause
The Cardiovascular Impact of Hot Flushes
The overall objective of this study is to examine the physiological responses that occur during a hot flush in postmenopausal women. The following specific aims will be executed to reach the overall objective of this study.
- Trial name
- NCT05251324
- Testing
- Hot Flush Induction
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Facial Flushing
Treatment of Facial Flushing With Botulinum Toxin A Injections
The purpose of this study is to find out if botulinum toxin A (botox®) can be used to treat facial flushing. This study is a pilot study designed to determine feasibility of these procedures.
- Trial name
- NCT02216838
- Testing
- botulinum toxin A, Saline Control
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Infertility
Follicular Flushing Outcomes in Singles Versus Double Lumen Oocyte Retrieval Needles in Poor Responding Patients
In this study, the investigators aimed to evaluate to the efficacy of the needle type used in follicular flushing in oocyte retrieval in the poorest responders undergoing IVF.
- Trial name
- needles(opu) (NCT02391155)
- Testing
- single lumen needle in oocyte retrieval, double lumen needle in oocyte retrieval
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Baskent University
Vasomotor Symptoms
Goji Berry and Vasomotor Symptoms Pilot Study
The goal of this clinical trial is to compare two forms of goji berry powder-whole goji berry powder and goji juice powder-in peri- and postmenopausal women aged 40-65 years who experience frequent vasomotor symptoms (hot…
- Trial name
- GOJI-VMS (NCT07660315)
- Testing
- Goji Berry Juice Powder, Goji Berry Powder
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Infertility
Does Follicular Flushing Improve the Outcome in Monofollicular IVF Therapy?
Follicular aspiration as well as follicular flushing are standardized techniques and have been practiced in polyfollicular IVF (in vitro fertilization) therapy for years.
- Trial name
- Flushing (NCT02641808)
- Testing
- follicular flushing, no follicular flushing
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Schizophrenia, Cannabis Abuse
Niacin Flushing as Marker of Cannabis Effects on Arachidonic Acid Pathways in Schizophrenia
Increasing evidence suggests modulating effects of cannabinoids on time of onset, severity, and outcome of schizophrenia. Efforts to discover the underlying pathomechanism have led to the assumption of gene x environment…
- Trial name
- NCT00376233
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Jena
Vasomotor Symptoms, Menopausal Symptoms
Estetrol for the Treatment of Moderate to Severe Vasomotor Symptoms in Postmenopausal Women (E4Comfort II)
A two-part study designed to evaluate the effect of Estetrol (E4) 15 mg, 20 mg, or placebo on the severity and frequency of vasomotor symptoms (VMS) in the Efficacy Study Part and the safety of E4 20 mg in the Safety Study Part.
- Trial name
- E4Comfort II (NCT04090957)
- Testing
- Estetrol oral tablet
- Where
- 117 sites in United States, Canada
- Volunteers
- 1,015 people, healthy volunteers welcome
- Sponsor
- Estetra
Major Depressive Disorder
A Pilot Study on Effect of add-on Sulforaphane to SSRIs and Application of Niacin Skin Flush Response Test in Major Depressive Disorder
A 12-week, randomized controlled trial (RCT) will be conducted to explore the effect of add-on sulforaphane (SFN) to selective serotonin reuptake inhibitors (SSRIs) for major depressive disorder (MDD).
- Trial name
- NCT05148169
- Testing
- SSRIs, SSRI plus Sulforaphane
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Flushing, Alcohol-Related Disorders
Treatment of Asian Flushing Syndrome With Topical Alpha Agonists
Asian Flushing Syndrome (AFS) is a genetic disease affecting approximately 70% of patients of East Asian descent characterized by severe flushing with minimal ethanol consumption.
- Conditions
- Flushing, Alcohol-Related Disorders, Aldehyde Dehydrogenase Deficiency
- Trial name
- NCT03497442
- Testing
- Brimonidine Tartrate
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Menopause
The Efficacy of ACupuncture On Menopausal Symptoms (ACOM)
As a natural part of the menopause the ovaries production of sex hormones declines. This can lead to different menopausal related symptoms.
- Trial name
- ACOM (NCT02746497)
- Testing
- Acupuncture
- Where
- Denmark
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Menopause-Hot Flashes
Flushes and Sertraline Trial
The primary outcome of FAST (a randomized double-blinded, placebo controlled, trial of the effect of sertraline vs. placebo in reducing the incidence and severity of hot flushes in healthy women) is to determine if 6 weeks of…
- Trial name
- NCT00283192
- Testing
- Sertraline
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco