Clinical trials: Focus of Study
Moderate or Severe Submental Fullness
Phase 3 Study of Deoxycholic Acid Injection (ATX-101) Versus Placebo for the Reduction of Localized Subcutaneous Fat in the Submental Area
To evaluate the safety and efficacy of deoxycholic acid injection in the reduction of submental fat (fat below the chin).
- Trial name
- REFINE-1 (NCT01542034)
- Testing
- Deoxycholic acid injection
- Where
- 36 sites in United States, Canada
- Volunteers
- 506 people, healthy volunteers welcome
- Sponsor
- Kythera Biopharmaceuticals
Urinary Incontinence
In-person Focus Groups in the Management of Urinary Incontinence in Women
The purpose of this study is to investigate how a support group with other individuals who share the condition urinary incontinence (UI) impacts patients experience with management of urinary incontinence.
- Trial name
- NCT05395793
- Testing
- Support Group
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Study Focus is Healthy Contact Lens Wearers
Evaluation of an Investigational Multi-Purpose Solution (MPS)
The purpose of this study is to evaluate the safety and effectiveness of an investigational multi-purpose contact lens solution.
- Trial name
- NCT00961051
- Testing
- Investigational MPS, Opti-Free
- Where
- 9 sites in United States
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Focus of Study: Work Conditions
Evaluating the Health Benefits of Workplace Policies and Practices - Phase II
Although the prevalence of "family-friendly" policies in US workplaces has increased dramatically, few have been studied using scientifically sound designs.
- Trial name
- WFHS (NCT02050204)
- Testing
- Intervention
- Where
- United States
- Volunteers
- 2,753 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Posttraumatic Stress Disorder
The Effectiveness of CFT for Reducing Self-criticism in Patients With Complex PTSD: a Single-case Experimental Study
PTSD is a mental disorder including psychological symptoms related to severe traumatic event(s). PTSD can negatively affect people's functioning in several life domains.
- Trial name
- NCT05791760
- Testing
- Compassion-focused therapy (CFT) for complex PTSD
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Twente
Gingival Recession, Localized
Effect of Botulinum Toxin-A on Free Gingival Graft
The aim of this study was to examine the effects of Botulinum Toxin-A (BTX-A) injection to the mental muscle on the free gingival graft (FGG) operation.
- Trial name
- NCT05822323
- Testing
- BTX-A, free gingival graft
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kevser Sokmen
Adolescent Behavior, Adolescent - Emotional Problem
Family-Focused Adolescent & Lifelong Health Promotion
The aim of this study is to adapt the Parenting for Lifelong Health for Parents and Teens (PLH) with the Helping Adolescents Thrive Comics in North Macedonia and the Republic of Moldova and conduct a pilot feasibility study of…
- Conditions
- Adolescent Behavior, Adolescent - Emotional Problem, Psychological Well-Being, Parent-Child Relations
- Trial name
- FLOURISH (NCT05930535)
- Testing
- Parenting for Lifelong Health for Parents and Teens
- Where
- 2 sites in Moldova, North Macedonia
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University of Klagenfurt
Study Focus: Simulation and Proficiency Based Training
Proficiency Based Training in Surgery - Employing An Arthroscopic Bankart Repair
This study examines in a prospective, randomized and blinded study design the impact of a proficiency based training methodology on the acquisition of arthroscopic surgical skills employing both a dry shoulder simulator model…
- Trial name
- NCT01921621
- Testing
- Group B - Simulation Training, Group C - Proficiency Based Progression
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Arthroscopy Association of North America
Clinical Competence
Evaluation of a Chatbot With CALMO (Chatbot-Assisted Learning Model) to Enhance Clinical Learning in Nursing Students
The present proposed study will design and develop a chatbot to support graduating nursing students' clinical learning. The efficacy of this chatbot technology will be evaluated, using a mixed methods quasi-experimental design.
- Trial name
- CALMO (NCT06780228)
- Testing
- chatbot-assisted clinical learning
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Caritas Institute of Higher Education
Body Sculpting
A Multicenter,2-Arm,Randomized,Controlled Study Evaluate the Effectiveness of the UltraShape® Contour I VER 3.1 System for Non-Invasive Reduction in Abdominal Circumference
The primary objective of this study is to evaluate the effectiveness of the Contour I VER 3.1 System on abdominal midsection circumference reduction relative to no treatment.
- Trial name
- NCT01462201
- Testing
- Non Invasive Ultrasound
- Where
- 5 sites in United States, Israel
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- UltraShape
Focus of Study: Bicycle Helmet Wearing Compliance
Prevention of Traumatic Brain Injury in Youth and Adolescents
The hypothesis was that the implementation of a Safe Kids East Central brain injury prevention program targeting children and caregivers admitted to the Georgia Health Sciences University Children's Medical Center is feasible and…
- Trial name
- NCT01629121
- Testing
- education intervention
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Augusta University
Cardiac Arrest
Simulation-Based Study of Adding Video Communication to Dispatch Instruction
The purpose of this study is to determine whether adding interactive video communication to dispatch instruction improves the quality of bystander cardiopulmonary resuscitation in simulated cardiac arrests.
- Trial name
- NCT00564616
- Testing
- video cell phone
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Focus of Study: Usability of a Tool for Structured Assessment of and Feedback to Trainee Surgeons
Testing NOTSSdk in the Clinical Setting
The purpose of this study is to test the use of a tool (NOTSSdk)to assess and provide feedback to trainee surgeons' non-technical skills.
- Trial name
- NCT01773525
- Where
- Denmark
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Herlev Hospital
Post Intensive Care Syndrome, Anxiety
Sensation Awareness Focused Training for Spouses
The purpose of the feasibility study is prevention of Post Intensive Care Syndrome in Family (PICS-F), specifically in spouses of critically ill, mechanically ventilated patients, using a nonpharmacological intervention called…
- Conditions
- Post Intensive Care Syndrome, Anxiety, Depression, Posttraumatic Stress Disorder
- Trial name
- SAF-T (NCT03129204)
- Testing
- SAF-T
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Malaria, Vivax
Tafenoquine Thorough QTc Study in Healthy Subjects
This will be a randomized, single-blind, placebo controlled, parallel group study. Approximately 260 subjects will be enrolled in five groups.
- Trial name
- NCT01928914
- Testing
- Tafenoquine 300mg, Tafenoquine 600mg, Tafenoquine 1200mg
- Where
- 2 sites in United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Presbyopia Condition
A Randomized, Active-Controlled, Double-Masked, Crossover Study to Evaluate the Clinical Performance of Deseyne (Vifilcon C) Daily Disposable Soft Contact Lens for Presbyopia Extended Depth of Focus (EDOF)
The goal of this clinical trial is to learn if the contact lens we are testing will work to extend the range of clear focus at distance to provide an increase in clear vision at closer ranges without the additional need for…
- Trial name
- EDOF (NCT06698731)
- Testing
- Test lens, Control lens
- Where
- 3 sites in United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Bruno Vision Care
Birth, First, Experience, Life
The Effect of Focus on Vaginal Examination Experience and Pain Level: a Randomized Controlled Trial
Vaginal examination contains many negative emotions such as pain, fear, stress, and discomfort for women. When the literature was examined, no study was found in which the focus method was used to reduce or eliminate the feelings…
- Conditions
- Birth, First, Experience, Life, Pain
- Trial name
- NCT05471219
- Testing
- Primiparous pregnant women who will undergo vaginal examination by focusing on visual traces
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Dilek Yigit Vural
MSM, HIV Infections
Risk Taking Behaviour in MSM and the Denial of Sexually Transmitted Diseases and HIV
Four focus groups , each of 10-15 males, ages 20-50 years old, MSM will be conducted by a medical sociologist. Two groups will be HIV negative participants and two groups of HIV positive MSM. Every group will meet for two hours.
- Conditions
- MSM, HIV Infections, Risky Behaviors
- Trial name
- MSM HIV (NCT01279005)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Prostate Cancer
Allogeneic Human Bone Marrow Derived Mesenchymal Stem Cells in Localized Prostate Cancer
The objective of this study is to determine if systemically infused allogeneic bone marrow derived mesenchymal stem cells (MSC) home to sites of prostate cancer in men with localized adenocarcinoma of the prostate that are…
- Trial name
- MSC (NCT01983709)
- Testing
- Allogeneic Human Mesenchymal Stem Cells
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Drug Resistant Epilepsy, Focal Seizure
Safety, Tolerability, and Pharmacokinetics (PK) of Single and Multiple Ascending Oral Doses of iQ-007
This is a randomized, double-blind, placebo-controlled study conducted in healthy adult volunteers to assess the safety, tolerability and pharmacokinetics of iQ-007.
- Trial name
- NCT06899230
- Testing
- iQ-007
- Where
- Australia
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- iQure Australia Pty Ltd