Clinical trials: Focus of Study
Cognitive Performance (Focus)
The Effect of a Phospholipid Drink on Cognitive Performance Under Acute Stress
The study will explore the effects of a 6-week phospholipid drink intervention on the cognitive performance and physiological and subjective stress parameters of males following a repeated psychosocial/physical stressor.
- Trial name
- NCT01879813
- Testing
- Phospholipid drink
- Where
- United Kingdom
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Cardiac Disease
A Study of Electrocardiogram and Focused Cardiac Ultrasound for Enhanced Cardiac Disease Screening
The purpose of this study is to evaluate and compare the effectiveness of active screening for SHD in asymptomatic outpatients referred for an ECG, using a combination of AI-ECG and FOCUS.
- Trial name
- SCAN (NCT06891222)
- Testing
- AI-ECG (artificial intelligence-enabled electrocardiogram), Focus Screening (focused cardiac ultrasonography)
- Where
- United States
- Volunteers
- 2,705 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Tuberous Sclerosis Complex (TSC), Focal Cortical Dysplasia
Phase 1, Open-label, Drug-drug Interaction Study to Assess Effect Between Radiprodil and the Co-administered Drugs.
This is a Phase 1, open-label, 3-period study to determine radiprodil's potential to act as a perpetrator of cytochrome P-450 (CYP) metabolic pathways and transporter pathways.
- Conditions
- Tuberous Sclerosis Complex (TSC), Focal Cortical Dysplasia, Other Neurological Disorders
- Trial name
- NCT06975605
- Testing
- Radiprodil + co-administered drugs
- Where
- Australia
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- GRIN Therapeutics, Inc.
Focus of Study: Carotenoid Absorption
Comparison of Carotenoid Bioavailability From Fresh Papaya, Tomato and Carrot
The goal of this study is to determine if papaya fruits are an exceptionally good food source for carotenoids in humans, particularly when compared more common carotenoid sources like carrots and tomatoes.
- Trial name
- NCT01748916
- Testing
- Papaya, Carrot, Tomato
- Where
- 2 sites in United States, Costa Rica
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Hairy Cell Leukemia (HCL), Chronic Lymphocytic Leukemia (CLL)
Collection of Human Samples to Study Hairy Cell and Other Leukemias, and to Develop Recombinant Immunotoxins for Cancer Treatment
Background: Researchers who are studying hairy cell leukemia, and how the disease compares with other disorders, are interested in obtaining additional samples from leukemia patients and healthy volunteers.
- Conditions
- Hairy Cell Leukemia (HCL), Chronic Lymphocytic Leukemia (CLL), Non-Hodgkins Lymphoma (NHL), Cutaneous T Cell Lymphoma (CTCL)
- Trial name
- NCT01087333
- Where
- United States
- Volunteers
- 1,263 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Visual To Compare the Visual Outcome Between AcrySof™ IQ Vivity™ and TECNIS Synergy™ Intraocular Lens (Model ZFR00V )
A Comparative Study of Visual Outcome of Two Extended Depth of Focus Intraocular Lenses After Cataract Surgery
The investigators aim to compare the visual performance of the most recently introduced extended depth of focus intraocular lenses ; AcrySofTM IQ VivityTM and TECNIS SynergyTM ( an extended depth of focus IOL ) regarding the…
- Trial name
- NCT05647421
- Testing
- IOL implantation
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Post Intensive Care Syndrome, Anxiety
Sensation Awareness Focused Training for Spouses
The purpose of the feasibility study is prevention of Post Intensive Care Syndrome in Family (PICS-F), specifically in spouses of critically ill, mechanically ventilated patients, using a nonpharmacological intervention called…
- Conditions
- Post Intensive Care Syndrome, Anxiety, Depression, Posttraumatic Stress Disorder
- Trial name
- SAF-T (NCT03129204)
- Testing
- SAF-T
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Prostate Cancer
The Efficacy and Safety of Composite Steep-pulse Treatment Apparatus Used in Prostate Cancer Focal Therapy
This trial is studying the effects and safety in treating patients with local prostate cancer with a new IRE device called Composite Steep-pulse Treatment Apparatus.
- Trial name
- NCT03315585
- Testing
- steep pulse device
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Second Military Medical University
Anatomic Stage 0 Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8
A Dietary Supplement (Resistant Potato Starch) for Reducing Musculoskeletal Symptoms in Individuals Planning to Receive Aromatase Inhibitor Therapy, AIMSS-RPS Trial
This phase II trial tests the safety and effectiveness of a dietary supplement called resistant potato starch for reducing musculoskeletal symptoms in patients with stage 0-III breast cancer or who are at high risk for breast…
- Conditions
- Anatomic Stage 0 Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8
- Trial name
- AIMSS-RPS (NCT07443943)
- Testing
- Starch, Potato
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Michigan Rogel Cancer Center
Blood Pressure
B40 Non-Invasive Blood Pressure Equivalency Study
The purpose of this study is to demonstrate equivalency of the GE Healthcare B40 Patient Monitor noninvasive blood pressure (NIBP) parameter compared to the reference device.
- Trial name
- NCT01546285
- Testing
- Blood Pressure Readings on B40 Patient Monitor
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- GE Healthcare
Treatment of Adipose Tissue in the Thighs
Treatment of Subcutaneous Adipose Tissue in the Thighs Using High Intensity Focused Ultrasound
The purpose of this study is to assess the safety and efficacy of treatment with the Liposonix System (Model 2) for the circumferential reduction of subcutaneous adipose tissue (SAT) of the thighs.
- Trial name
- NCT01823653
- Testing
- Liposonix System (Model 2)
- Where
- 4 sites in United States, Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Solta Medical
Study Focus 1:Glycaemic Index, Study Focus 2:Glycaemic Response
Blood Glucose and Insulin Responses to Snack Food Products
The purpose of this study is to assess the effects of added food ingredients, when baked into a snack food product, on glycaemic index of the product and glycaemic and insulinemic responses to the product in healthy adults.
- Conditions
- Study Focus 1:Glycaemic Index, Study Focus 2:Glycaemic Response, Study Focus 3:Insulinemic Response
- Trial name
- NCT01341769
- Testing
- Dietary Intervention
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mondelēz International, Inc.
Breast Cancer
The HIFUB Study (HIFU in Breast Cancer)
High Intensity Focused Ultrasound (HIFU) is a new method of treating solid tumours by thermally ablating them. It has been used in a number of different types of cancers but there is little information on its use in invasive…
- Trial name
- HIFUB (NCT05350059)
- Testing
- High Intensity Focused Ultrasound (HIFU) to the Breast Cancer
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Epilepsy, Focal Cortical Dysplasia
First-in-human Experience Using Novel Ultraflexible Low-impedance Electrode Arrays: an IDEAL Stage 1 Study
The goal of this first-in-human study is to evaluate a novel ultraflexible microelectrode in children undergoing neurosurgery to remove tissue that causes epilepsy (seizures) in focal cortical dysplasia (FCD) or long-term…
- Trial name
- NCT06116279
- Testing
- Insertion of electrode during planned neurosurgery for epilepsy
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Focus: Estrogen-free Oral Contraception
Efficacy Study of Two Continuous Regimens of Oral Daily 5 mg or 10 mg of Ulipristal Acetate (UPA), Versus a Dose of 5.0mg UPA for 24/4 Days
To compare the pharmacodynamic effects of 2 continuous dose regimens of ulipristal acetate 5.0 and 10.0 mg-only oral contraception, versus a 24/4 day regimen of UPA 5.0 mg.
- Trial name
- CCN013 (NCT01953679)
- Testing
- Ulipristal Acetate
- Where
- 10 sites in United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Premier Research
Focus of Study is to Determine Efficacy of Compex
Compex Use With Delayed Onset Muscle Soreness: A Comparison to Other Methods
The purpose of this research study is to determine if the application of ice, control group, or a muscle stimulation program from the Compex® series can help reduce or eliminate delayed muscle soreness from performing leg…
- Trial name
- NCT01967121
- Testing
- Compex unit's Active Recovery® program, Ice application
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Hepatitis C Virus Infection
Screening, Treatment, and Eradication of Hep C
The aim of this study is to assess the HCV screening rate in Arizona by identification of potential HCV patients/subjects through different methods of communication - text message, email, social media, radio, newspaper ads, and…
- Trial name
- NCT05071261
- Testing
- Hepatitis C Virus Screening
- Volunteers
- 112,136 people, healthy volunteers welcome
- Sponsor
- Liver Institute PLLC
Hope, Nursing
The Effect of the Solution-Focused Approach on Social Participation Skills and Hope in Children Living in Residential Care Objective: This Study Aimed to Evaluate the Effect of a Solution-focused Approach Program on the Hope Levels and Social Participation Skills of Children Living in Institutional
his study examined whether a solution-focused approach program could improve hope and social participation skills in children living in institutional care.
- Conditions
- Hope, Nursing, Social Acceptance
- Trial name
- NCT07135908
- Testing
- solution-oriented approach
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Muş Alparslan University
Liver Health
Dietary Intervention Study on Liver Health in Young Adults
This prospective randomized dietary intervention study investigates the effects of two dietary approaches on liver health in young adults over a 12-week period.
- Trial name
- NCT07786831
- Testing
- Mediterranean Diet Intervention, General Healthy Diet Intervention
- Where
- Austria
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hochschule Campus Wien (University of Applied Sciences Campus Vienna)
Focus of the Study is to Promote Healthy Hearing
Game to Improve Hearing Health Care Outcomes
The investigators are studying the educational potential of games, with the goal of developing a game to improve learning and promote healthy hearing behaviors.
- Trial name
- NoisyCity (NCT02946567)
- Testing
- Noisy City information about hearing health care, Generic Game
- Where
- United States
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Photozig, Inc.