Clinical trials: Follow-Up Study
Child Development
The MOM Program: 5 Year Follow-up Study of a Home Visiting Program at The Children's Hospital of Philadelphia
The purpose of the MOM Program Continuation is to promote child development by helping families become more competent in accessing and using available health, developmental and educational resources.
- Trial name
- MOM Program (NCT00231179)
- Testing
- Home visiting professional support model, Control
- Where
- United States
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Myotonic Dystrophy 1, Myotonic Dystrophy 2
Tracking the Brain in Myotonic Dystrophies: a 5-year Longitudinal Follow-up Study
The natural history of brain affection in myotonic dystrophy types 1 and 2 is still unknown. The investigators designed a 5-year longitudinal neuropsychological and neuroimaging follow-up study to address this issue.
- Trial name
- NCT02729597
- Testing
- medical history, neurological clinical examination, neuropsychological testing
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bonn
Disaster Medicine, Difficult Intravenous Access
EASI Access II --- Follow-up Study to the EASI Access Trial
Test whether Basic Life Support (BLS) providers can successfully place Enzymatically Augmented Subcutaneous Infusion (EASI) Access lines for subcutaneous infusion, and characterize intravascular absorption of EASI-administered…
- Conditions
- Disaster Medicine, Difficult Intravenous Access, Dehydration
- Trial name
- NCT00740727
- Testing
- Human recombinant hyaluronidase (HRH), Enzymatically Augmented Subcutaneous Infusion (EASI) line placement
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Deep Venous Thrombosis
Venous Thrombus Investigation With Contrast Enhanced Ultrasound Imaging
Background: During the repair process of deep venous thrombosis, capillary formation is seen from day 18 to day 25. Contrast agent investigation is well known to detect small vessels in arterial disease.
- Trial name
- NCT00677846
- Where
- Germany
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University Hospital Freiburg
Cataract, Lens Opacities
PMCF Study on EDOF (Isopure) vs Monofocal (Micropure) IOL
Multicenter, prospective, randomised, controlled, single-blind post-market clinical follow-up (PMCF) study to compare the clinical outcomes of an enhanced depth of focus (EDOF) IOL with the outcomes obtained with a monofocal…
- Trial name
- PHY2001 (NCT04249492)
- Testing
- IOL implantation experimental (Isopure 1.2.3.), IOL implantation active comparator (Micropure 1.2.3.)
- Where
- 12 sites in Austria, Czechia and 4 more
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Running, Wounds and Injuries
Effect of a Gait Retraining Intervention and a Minimalist Footwear Transition on Foot-ankle Strength, Running Economy and Injury in Endurance Runners.
The main aim is to determine whether a gait retraining intervention will improve the strength of the foot-ankle muscle, the running economy and reduce the injury incidence in a one-year follow-up study.
- Conditions
- Running, Wounds and Injuries, Oxygen Consumption
- Trial name
- NCT05499871
- Testing
- Gait retraining intervention, Transition to minimalist footwear.
- Where
- Belgium
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Liege
Fat Mass, Risk Factors Cardiovascular Disease
Follow up Study of Varapodio Trial: Effect of Longevity and Fasting Mimicking Diet on Risk Factors Age Correlated and Biomarkers of Aging
A large ongoing randomized, open-label trial aimed at evaluating the effects of two different dietary interventions, FMD and LD, on body composition and cardiovascular (CV) biomarkers in a real word population (NCT05698654) is…
- Conditions
- Fat Mass, Risk Factors Cardiovascular Disease, Epigenetic Aging, Metabolism Changes
- Trial name
- NCT07255300
- Testing
- fasting mimicking diet
- Where
- Italy
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Fondazione Valter Longo
Poverty
Comprehensive Follow-up of Low Income Families. A Cluster-randomized Study
In a cluster-randomized design, the study evaluates the effectiveness of a skill- training program for social work professionals with the aim of improving the follow-up of low income families within Norwegian labor and welfare…
- Trial name
- CRCT-HOLF (NCT03102775)
- Testing
- Comprehensive follow-up program for low-income families, local family projects
- Where
- 29 sites in Norway
- Volunteers
- 884 people, healthy volunteers welcome
- Sponsor
- Oslo Metropolitan University
Healing
Evaluation of Preferences of Consumers and Clinicians for the Management of Shave Biopsy Sites With a PolyMem Formulation Dressing or Current Standard of Care.
Shave biopsies are often uncomfortable during the healing process. This is a preliminary study to determine if patients and clinicians prefer using PolyMem formulating dressings on shave biopsy sites compared to the current…
- Trial name
- NCT00727870
- Testing
- Shapes by PolyMem dressing, Shapes by PolyMem Silver Dressing, Shapes by PolyMem on one site and Shapes by PolyMem Silver dressing on second site
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ferris Mfg. Corp.
Weight Loss, Gut Microbiome
Low Sugar Protein Pacing, Intermittent Fasting Diet in Men and Women
This study will systematically quantify the effects of protein pacing and intermittent fasting (P-IF) on total and regional (abdominal) body composition (lean mass and fat mass), blood glucose and lipids, and anti-aging…
- Conditions
- Weight Loss, Gut Microbiome, Anti-Aging
- Trial name
- NCT04327141
- Testing
- P-IF, HH
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Skidmore College
Triage, Low Acuity Patients
FOllow-up of LOW-acuity Patients After REdirection From a Swiss Emergency Department Using an Electronic TRIage Application
Emergency department (ED) overcrowding is a growing issue, affecting patient safety, healthcare quality, and hospital efficiency.
- Conditions
- Triage, Low Acuity Patients, Health Literacy Level, Non-urgent Emergencies
- Trial name
- FO-LOW-RETRI (NCT06971419)
- Testing
- intervention is the use of aTriage-Based Patient Redirection Using an Electronic Decision Support Toolin the emergency department (ED)
- Where
- Switzerland
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Hôpital Fribourgeois
Body Fat Disorder
Extended Follow-Up Study for Subjects Who Participated in 2010 Study
This study is being performed to follow up on subjects who participated in the initial study (ZA10-001) in 2010.
- Trial name
- JUNO (NCT01579487)
- Testing
- The Zeltiq System
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Zeltiq Aesthetics
Obesity, Cognitive Disorder
Emotional Regulation, Cognition, Impulsivity and Reward System in Obesity: A Prospective Study of Bariatric Surgery
This research investigates obesity and associated psychiatric symptoms and disorders in a wide range of perspectives, to demonstrate the effects of obesity on the brain.
- Trial name
- NCT03528044
- Testing
- Bariatric surgery
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Koç University
Halitosis
Evaluation of Halitosis After Treatment With Photodynamic Therapy Associated With Periodontal Treatment
The aim of this randomized, controlled clinical trial was to treat oral halitosis in healthy adults with photodynamic therapy associated with periodontal treatment and follow them up for 3 months.
- Trial name
- Halitosis (NCT03996915)
- Testing
- Pdt Photodynamic Therapy, tongue scrapper
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Male Circumcision, HIV Prevention
Follow Up Study to Evaluate a Non-Surgical Device for Adult Male Circumcision for Screen Failure Subjects
It is well known from a range of observational and epidemiological studies that the lifetime risk of acquiring HIV among males can be significantly reduced via circumcision by 53%-60% and by up to 73% in post-trial observation.
- Conditions
- Male Circumcision, HIV Prevention, Screen Failure Subjects, Narrow Foreskin
- Trial name
- RMC-05 (NCT02281435)
- Testing
- PrePex™ device
- Where
- Rwanda
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Rwanda
Colorectal Cancer
The Effects of Vitamin B-6 Status on Homocysteine, Oxidative Stress, One-carbon Metabolism and Methylation: Cross-section, Case-control, Intervention and Follow-up Studies in Colorectal Cancer
Vitamin B-6, folate and homocysteine may play a critical role in the colorectal cancer progression. This is a 4-y study and the specific aims are: 1) to compare vitamin B-6, folate and homocysteine status, oxidative stress…
- Trial name
- NCT01426490
- Testing
- Vitamin C, Vitamin B6, Folic acid
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Taichung Veterans General Hospital
Autism Spectrum Disorders
A Study of a Developmental,Individual-Difference,Relationship-Bases/Floortime Intervention for Children With Autistic
Thirty eight autistic spectrum disorder children age 2-6 years recruited into the study. The new treatment intervention is based on the DIR Model. Parents will be coached at the start and then every 3-4 months for 1 year.
- Trial name
- DIR (NCT00954213)
- Testing
- DIR/Floortime parent intervention
- Where
- Thailand
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Alcoholism, Substance-Related Disorders
Intranasal Oxytocin Effects in Alcohol Withdrawal and Dependence; Follow-up Study
This study is an assessment of the long-term effect of oxytocin nasal spray on alcohol withdrawal and dependence in adults admitted for detoxification of alcohol after 60 days and 1 year.
- Trial name
- NCT03339024
- Testing
- intranasal oxytocin spray, intranasal spray without oxytocin
- Where
- Norway
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Pulmonary Disease, Chronic Obstructive, Pulmonary Emphysema
Longitudinal Follow up to Assess Biomarkers Predictive of Emphysema Progression in Patients With COPD (Chronic Obstructive Pulmonary Disease)
The study will include 60 healthy subjects (ex-smoker without any airflow limitation), 125 COPD GOLD (global initiative for chronic obstructive lung disease) I , 125 COPD GOLD II, 125 COPD GOLD III and up to 20 patients with COPD…
- Trial name
- NCT02719184
- Where
- 51 sites in United States, Belgium and 10 more
- Volunteers
- 463 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Infant, Very Low Birth Weight
OptiMoM Grows Up: 5.5-year Follow-up of the OptiMoM Fortifier Study
In Canada, the leading cause of long-term disability in children is being born at very low birth weight (VLBW). To help improve outcomes, nutrition is a modifiable aspect of infant care.
- Trial name
- NCT04308902
- Testing
- VLBW, Term-born Comparison
- Where
- Canada
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children