Clinical trials: Food Effect
Healthy Volunteers
Food Effect Study of AG-221 in Healthy Male Subjects
AG-221 is a first-in-class drug targeted specifically to inhibit the IDH2 enzyme. Small molecule inhibition of the IDH enzyme represents a new, targeted approach to cancer treatment.
- Trial name
- NCT02218346
- Testing
- AG221
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Agios Pharmaceuticals, Inc.
Healthy Participants
Evaluate the Effects of Food on the Pharmacokinetics of SIM0270
This is a randomized, open label, single dose, two-period, crossover trial phase I study. The purpose of this study is to evaluate the food effect on the pharmacokinetics（PK） of SIM0270 after oral administration under fasted…
- Trial name
- NCT06536036
- Testing
- SIM0270
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Jiangsu Simcere Pharmaceutical Co., Ltd.
Healthy
Safety and Tolerability Study of Multiple Doses of PF-06305591
Safety, tolerability and PK of repeated doses of PF-06305591 will be evaluated in young healthy volunteers toghether with food effect on relative bioavailability of solid formulation after single dose.
- Trial name
- NCT01776619
- Testing
- PF-06305591
- Where
- Belgium
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Pfizer
Diabete Type 2, Obesity
Effects of Plant Based Lipids on Glucose Regulation and Cognitive Variables
The overall goal is to increase the knowledge that can be used for the development of food products with anti-diabetic properties, with the purpose to facilitate healthier food choices for people.
- Trial name
- NCT05276128
- Testing
- lipids
- Where
- 2 sites in Sweden
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Lund University
Epilepsy
Bioequivalence and Food Effect of 250mg of Lamotrigine XR
This study intends to demonstrate bioequivalence and lack of food effect on 250mg lamotrigine XR in healthy male and female volunteers
- Trial name
- NCT00605371
- Testing
- Lamotrigine tablet, Lamotrigine caplet
- Where
- United States
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Heart Failure
A Clinical Study of HRS-5765 in Healthy Participants
The purpose of this phase I study is to evaluate the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of HRS-5765 in healthy participants.
- Trial name
- NCT07551167
- Testing
- HRS-5765 Tablet
- Where
- China
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Chengdu Suncadia Medicine Co., Ltd.
Physical Activity, Energy Intake
Effects of Acute Sleep Deprivation on Human Behaviours
This study will investigate whether acute sleep deprivation affects appetite, eating behavior, and physical activity in both regular exercisers and physically inactive individuals.
- Conditions
- Physical Activity, Energy Intake, Appetite, Food Choice
- Trial name
- NCT07393607
- Testing
- Normal sleep, Partial sleep deprivation
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Healthy Adult Subjects
ONO-7746 Study in Healthy Adult Subject
The primary objective of this study is to evaluate the safety and tolerability of NON-7746 in healthy adult subjects. The secondary objectives are to characterize the pharmacokinetic and pharmacodynamic profiles of ONO-7746 and…
- Trial name
- NCT01106664
- Testing
- ONO-7746
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Ono Pharmaceutical Co., Ltd.
Liver Stiffness
Effect of Thoracic Diameter and Food Intake on Fibroscan® Results
The study aims to deliver scientific data regarding the accuracy of the two different-sized Fibroscan® probes on patients with different thoracic diameter to gain more knowledge of the handling and measuring quality of the…
- Trial name
- FS (NCT03947359)
- Testing
- Fibroscan Touch 502 M probe, Fibroscan Touch 502 S probe
- Where
- Austria
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Healthy Volunteer
Study to Assess How Different Oral Formulations of Ubrogepant Move Through the Body in Healthy Adult Participants
This study will assess how different oral formulations of ubrogepant move through the body in healthy adult participants under fasting and fed conditions.
- Trial name
- NCT07680686
- Testing
- Ubrogepant
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- AbbVie
Food Habits, Food Preferences
Effects of Experiential Learning on Vegetable Intake in Preschool Children
The aim of this cluster randomized control trial is to test the efficacy of providing experience of a target novel vegetable within the context of an interactive story time to increase intake of the target novel vegetable in…
- Conditions
- Food Habits, Food Preferences, Health Behavior, Diet Habit
- Trial name
- NCT03400566
- Testing
- Narrative, Experiential
- Where
- United Kingdom
- Volunteers
- 337 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Diabetes Mellitus, Type 2, Insulin Resistance
Study of Carrageenan's Effect on Insulin Resistance in Humans
The purpose of this study is to determine whether the ingestion of the common food additive carrageenan contributes to insulin resistance and thus to the pathogenesis of type 2 diabetes in humans.
- Trial name
- NCT02629705
- Testing
- Carrageenan
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Obesity
Effects of Inulin on Satiety and Food Intake
To assess the effect of inulin on appetite profile ratings, food intake and satiety hormones.
- Trial name
- Inulin (NCT01025375)
- Testing
- inulin
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Infant Growth, Infant Body Fat
Effect of Protein From Complementary Foods on Infant Growth, Body Composition and Gut Health
Current research shows that dairy protein accelerates infant weight gain, which is a risk factor for later on obesity and metabolic syndrome. However, dietary protein from other sources haven't been studied yet.
- Conditions
- Infant Growth, Infant Body Fat, Infant Gut Microbiome
- Trial name
- NCT02142647
- Testing
- a high-protein complementary diet with meat, a high-protein complementary diet with dairy
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Iron Deficiency
Evaluation of the Effects of an Exogenous Phytase on Iron Absorption From LNS Added to Complementary Foods
Previous studies on iron absorption have focused on the effects on the addition of iron absorption enhancers like ascorbic acid and EDTA to a meal and more recently the enzymatic phytic acid removal through phytase.
- Trial name
- NCT01991626
- Testing
- micronutrient powder, micronutrient powder (containing FeSO4), phytase, Iron pyrophosphate (FePP)
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Healthy
Food Effect And Relative Bioavailability Study Of Oxycodone in Healthy Volunteers
To estimate the effects of food on oxycodone pharmacokinetics after administration of 40 mg doses of PF-00345439 Formulation K and to estimate its relative bioavailability compared to PF-00345439 Formulation X in the fasted state…
- Trial name
- NCT01924676
- Testing
- Oxycodone
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Pain Therapeutics
Healthy Volunteers
Relative Bioavailability and Effect of Food Study With AGMB-129 in Healthy Participants
This is a single-center, open-label, single-dose, randomized, 3-period cross-over, Phase 1 study in healthy adult participants to assess the BA of AGMB-129 tablet formulation relative to that of the reference capsule formulation…
- Trial name
- NCT06397508
- Testing
- AGMB-129
- Where
- Belgium
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Agomab Spain S.L.
Healthy Volunteers
A Study to Investigate the Relative Bioavailability of 2 Tablet Formulations and the Effect of Food on the Pharmacokinetics of BGB-58067 in Healthy Participants
This study is being done to understand how the body processes 2 different tablet formulations of the study drug (BGB-58067) and how food intake influences the processing of the study drug by the body.
- Trial name
- NCT07712640
- Testing
- BGB-58067 Tablet (F-01 Formulation), BGB-58067 Tablet (F-02 Formulation)
- Where
- Australia
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- BeOne Medicines
Pregnancy
Effects of Dairy Foods on Adolescent Pregnant Mothers and Their Newborns
The purpose of the study is to evaluate the effects of different dietary calcium have on the pregnant teen mother and her newborn.
- Trial name
- NCT00320125
- Testing
- Orange juice plus calcium, Dairy products
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Utah
Healthy Volunteer
A Study to Assess the Relative Bioavailability And Food Effect of a Tablet Formulation of GDC-0276 in Healthy Participants
This open-label, randomized, 4-way crossover study in healthy participants will determine the relative bioavailability of the tablet formulation relative to the capsule formulation and the effect of a high-fat and low-fat meal on…
- Trial name
- NCT02856152
- Testing
- GDC-0276 capsule, GDC-0276 tablets
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Genentech, Inc.
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