Clinical trials: Food Intolerance
IBS, Food Intolerance
Confocal Laser Endomicroscopy in IBS Patients
This study will assess dynamic effects of two major antigens on the duodenal mucosa by confocal laser endomicroscopy (CLE). Patients will be blinded to the antigens used (wheat, yeast).
- Trial name
- NCT02313207
- Testing
- FODMAP
- Where
- Germany
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital Schleswig-Holstein
Diabetes Mellitus, Type 2, Metabolic Disease
The Effect on Metabolism, Food Intake and Preferences of a Knockout Gene Variant Involved in Carbohydrate Metabolism
Around 10% has type 2 diabetes in Greenland, despite being a practically unknown disease only six decades ago. The drastic increase is of great concern, especially considering the transition that have occurred during the same…
- Conditions
- Diabetes Mellitus, Type 2, Metabolic Disease, Sucrose Intolerance Congenital, Sucrase Isomaltase Deficiency
- Trial name
- NCT05375656
- Testing
- Cross-over study
- Where
- 2 sites in Greenland
- Volunteers
- 38 people
- Sponsor
- Steno Diabetes Center Copenhagen
Individual Difference, Food Sensitivity
Modifying Whey Protein Fortified Drinks and Foods
This study aims to investigate whether consumers differ in mouthdrying sensitivity and if mouthdrying can be modulated.
- Conditions
- Individual Difference, Food Sensitivity, Food Preferences
- Trial name
- NCT04869722
- Testing
- Liquid Model, Solid Model
- Where
- United Kingdom
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- University of Reading
Individual Difference, Food Sensitivity
Investigating the Influence of Age and Saliva Flow on the Perception of Protein Fortified Foods and Beverages
Brief Summary: This study aims to investigate whether protein fortification of foods and beverages causes mouthdrying and mucoadhesion and whether this is influenced by age and saliva flow.
- Conditions
- Individual Difference, Food Sensitivity, Food Preferences
- Trial name
- NCT04302779
- Testing
- Solid Model, Liquid Model
- Where
- United Kingdom
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Reading
Individual Difference, Food Sensitivity
Investigating Consumers Perception and Acceptance of Whey Beverages
Brief Summary: This study aims to investigate whether protein fortification of beverages causes mouthdrying and mucoadhesion and whether this is influenced by saliva flow.
- Conditions
- Individual Difference, Food Sensitivity, Food Preferences
- Trial name
- NCT04507399
- Testing
- Liquid Model
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Reading
Infections, Stool Flora
Efficacy and Safety of an Infant Formula With Milkfat and Prebiotics
The purpose of this clinical trial is to evaluate the effect of a new infant starter formula with added prebiotics (GOS) and with a fat blend rich in beta-palmitate.
- Conditions
- Infections, Stool Flora, Stool Biochemistry, Constipation
- Trial name
- NCT01603719
- Testing
- new infant formula with prebiotics and beta-palmitate
- Where
- Germany
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Waldkrankenhaus Protestant Hospital, Spandau
Appetitive Behavior, Individual Difference
The Influence of Fat Perception on Satiety From Consumption of Reduced Fat Snacks
The present study aims to investigate the effect of fat level and fat type of a snack on self-reported satiety and associated biomarkers. The relevant individual differences will also be investigated.
- Conditions
- Appetitive Behavior, Individual Difference, Food Sensitivity, Food Preferences
- Trial name
- NCT03585920
- Testing
- Expanded Corn Snack
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Reading
Individual Difference, Food Sensitivity
Investigation of the Perception of Protein Fortified Foods and Beverages
This study aims to investigate whether protein fortification of foods and beverages causes mouthdrying and mucoadhesion and whether this is influenced by age and saliva flow.
- Conditions
- Individual Difference, Food Sensitivity, Food Preferences
- Trial name
- NCT03798730
- Testing
- Solid Model, Liquid Model
- Where
- United Kingdom
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Reading
Inflammatory Bowel Diseases, Food Intolerance
Impact of Different Dietary IgGs on the Pathogenesis of IBD
Identify the association between certain food IgGs (Wheat, rice, broad beans, cow milk, eggs, chicken and beef) and the immunological response in patients with IBD
- Trial name
- NCT03885479
- Testing
- ELISA for the semi-quantitative analysis of serum food-specific IgGs against food-derived antigens
- Volunteers
- 150 people
- Sponsor
- Assiut University
Inflammatory Bowel Diseases, Irritable Bowel Syndrome
Fecal Calprotectin Collection Protocol
The primary objective is to obtain stool samples from subjects diagnosed with , and displaying signs and/or symptoms of IBD and/or IBS will be evaluated in this study.
- Conditions
- Inflammatory Bowel Diseases, Irritable Bowel Syndrome, Ulcerative Colitis, Crohn Disease
- Trial name
- CALFE (NCT03143517)
- Testing
- Stool collection
- Where
- 13 sites in United States
- Volunteers
- 240 people
- Sponsor
- DiaSorin Inc.
Food Intolerance, Celiac Disease
"Gluten Friendly" Treatment in Celiac Disease
A PROSPECTIVE, double blind, placebo-controlled trial
- Trial name
- GLUFR (NCT03137862)
- Testing
- Gluten free bread, Gluten friendly bread 3g/day, Gluten friendly bread 6g/day
- Where
- Italy
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Casa Sollievo della Sofferenza IRCCS
Food Intolerance, Histamine Intolerance
Study to Investigate the Effect of an Oral Diamine Oxidase Substitution (DAOsin) in Histamine Intolerant Patients on the Low Endogenous Diamine Oxidase Serum Activity
DAOsin is a food supplement for special medical purpose for the treatment of food intolerance provoked by histamine intake. In this uncontrolled, interventional pilot study the effect of an oral diamine oxidase substitution…
- Trial name
- NCT03298568
- Testing
- DAOsin
- Where
- Austria
- Volunteers
- 30 people
- Sponsor
- Sciotec Diagnostic Technologies GmbH
Irritable Bowel Syndrome
Irritable Bowel Syndrome and Food Sensitivity
The primary objective of the clinical trial portion of this study is to assess whether an individualized dietary plan based on a commercial food sensitivity assay provides specific benefit in a randomized controlled trial in…
- Trial name
- NCT02186743
- Testing
- Personalized Dietary Advice
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Yale University
Non-coeliac Gluten Sensitivity
Effect of AN-PEP Enzyme on Gluten Digestion in Gluten Sensitive Individuals
In this trial, the effect of a low and a high dose AN-PEP will be investigated in gluten sensitive individuals. Volunteers receive a breakfast with background (0.5 g) gluten.
- Trial name
- AN-PEP-03 (NCT02060864)
- Testing
- AN-PEP
- Where
- Sweden
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- DSM Food Specialties
Endomicroscopy, Inflammatory Bowel Syndrome
Endomicroscopy, IBS and Food Intolerance
Background: The immediate endoscopic identification and diagnosis of intraepithelial structures and immediate and delayed reactions to allergens in the mucosal surface of the gut are unmet goals in the diagnosis and management of…
- Conditions
- Endomicroscopy, Inflammatory Bowel Syndrome, Food Intolerance
- Trial name
- NCT01692613
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital Schleswig-Holstein
Irritable Bowel Disease
Effects of Fasting and Hydro Colon Therapy Plus Probiotics on GI Microbiota in Intolerances and Irritable Bowel Syndrome
Consequences of Colon Hydrotherapy plus probiotic intervention on composition of GI microbiota and well being are analysed in subjects claiming GI inconveniences due to Irritable Bowel Syndrome or food intolerances.
- Trial name
- MicFFGAH2013 (NCT02372201)
- Testing
- Hydro Colon Therapy plus probiotic
- Where
- Austria
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Vienna
Overweight and Obesity
IgG-mediated Food Test for Weight Loss
This study assessed the effect of an IgG-mediated food sensitivity test in combination with a food elimination diet on body composition and secondary outcomes in people who were overweight.
- Trial name
- NCT01592071
- Testing
- Replace reactive foods with non-reactive foods
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Miami
Milk Hypersensitivity, Food Sensitivity
Evaluation of the Efficacy of a New Formula in Infants With Cow's Milk Protein Allergy
The aim of the study is to show the efficacy, tolerance and nutritional adequacy of a newly developed hydrolyzed rice formula in infants with a proven cow's milk protein allergy.
- Conditions
- Milk Hypersensitivity, Food Sensitivity, Protein Allergy
- Trial name
- Paradice (NCT01998074)
- Testing
- extensively hydrolyzed rice protein formula
- Where
- Belgium
- Sponsor
- United Pharmaceuticals
Celiac Disease, Gluten
HLA-DQ2-gliadin Tetramer for Diagnosis of Celiac Disease
The investigators will evaluate the use of an HLA-DQ2-gliadin tetramer for staining of gluten specific T cells in the diagnostics of uncertain celiac disease.
- Trial name
- NCT01100099
- Testing
- Gluten challenge.
- Where
- Norway
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital